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Volumn 568, Issue 2, 2004, Pages 275-282

Clinicopathologic features in colorectal cancer patients with microsatellite instability

Author keywords

Colorectal cancer; DNA hypermethylation; Hereditary non polyposis colorectal cancer; Microsatellite instability; Mismatch repair; Sporadic colorectal cancer

Indexed keywords

FLUOROURACIL;

EID: 8144224215     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2004.05.025     Document Type: Article
Times cited : (85)

References (80)
  • 1
    • 0037260139 scopus 로고    scopus 로고
    • Cancer statistics
    • A. Jemal Cancer statistics CA Cancer J. Clin. 53 1 2003 5 26
    • (2003) CA Cancer J. Clin. , vol.53 , Issue.1 , pp. 5-26
    • Jemal, A.1
  • 2
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • L.A. Loeb Mutator phenotype may be required for multistage carcinogenesis Cancer Res. 51 12 1991 3075 3079
    • (1991) Cancer Res. , vol.51 , Issue.12 , pp. 3075-3079
    • Loeb, L.A.1
  • 3
    • 0016176530 scopus 로고
    • Errors in DNA replication as a basis of malignant changes
    • L.A. Loeb, C.F. Springgate, and N. Battula Errors in DNA replication as a basis of malignant changes Cancer Res. 34 9 1974 2311 2321
    • (1974) Cancer Res. , vol.34 , Issue.9 , pp. 2311-2321
    • Loeb, L.A.1    Springgate, C.F.2    Battula, N.3
  • 4
    • 0033941821 scopus 로고    scopus 로고
    • Pathology of hereditary nonpolyposis colorectal cancer
    • J.R. Jass Pathology of hereditary nonpolyposis colorectal cancer Ann. NY Acad. Sci. 910 2000 62 73 (discussion 73-4)
    • (2000) Ann. NY Acad. Sci. , vol.910 , pp. 62-73
    • Jass, J.R.1
  • 5
    • 0028877437 scopus 로고
    • Pathways of chromosome alteration in human epithelial cancers
    • B. Dutrillaux Pathways of chromosome alteration in human epithelial cancers Adv. Cancer Res. 67 1995 59 82
    • (1995) Adv. Cancer Res. , vol.67 , pp. 59-82
    • Dutrillaux, B.1
  • 6
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • C. Lengauer, K.W. Kinzler, and B. Vogelstein Genetic instability in colorectal cancers Nature 386 6625 1997 623 627
    • (1997) Nature , vol.386 , Issue.6625 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 7
    • 0028071904 scopus 로고
    • Multiple pathways leading to genomic instability and tumorigenesis
    • M.A. Sweezy, and R. Fishel Multiple pathways leading to genomic instability and tumorigenesis Ann. NY Acad. Sci. 726 1994 165 177
    • (1994) Ann. NY Acad. Sci. , vol.726 , pp. 165-177
    • Sweezy, M.A.1    Fishel, R.2
  • 8
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • E.R. Fearon, and B. Vogelstein A genetic model for colorectal tumorigenesis Cell 61 5 1990 759 767
    • (1990) Cell , vol.61 , Issue.5 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 9
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • B. Vogelstein Genetic alterations during colorectal-tumor development New Engl. J. Med. 319 9 1988 525 532
    • (1988) New Engl. J. Med. , vol.319 , Issue.9 , pp. 525-532
    • Vogelstein, B.1
  • 10
    • 0029549813 scopus 로고
    • Molecular genetics of colorectal cancer
    • E.R. Fearon Molecular genetics of colorectal cancer Ann. NY Acad. Sci. 768 1995 101 110
    • (1995) Ann. NY Acad. Sci. , vol.768 , pp. 101-110
    • Fearon, E.R.1
  • 11
    • 0029062884 scopus 로고
    • The deleted in colorectal cancer (DCC) gene: A candidate tumour suppressor gene encoding a cell surface protein with similarity to neural cell adhesion molecules
    • E.R. Fearon, and W.E. Pierceall The deleted in colorectal cancer (DCC) gene: a candidate tumour suppressor gene encoding a cell surface protein with similarity to neural cell adhesion molecules Cancer Surv. 24 1995 3 17
    • (1995) Cancer Surv. , vol.24 , pp. 3-17
    • Fearon, E.R.1    Pierceall, W.E.2
  • 12
    • 0032546360 scopus 로고    scopus 로고
    • Mutations of mitotic checkpoint genes in human cancers
    • D.P. Cahill Mutations of mitotic checkpoint genes in human cancers Nature 392 6673 1998 300 303
    • (1998) Nature , vol.392 , Issue.6673 , pp. 300-303
    • Cahill, D.P.1
  • 13
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • S.N. Thibodeau, G. Bren, and D. Schaid Microsatellite instability in cancer of the proximal colon Science 260 5109 1993 816 819
    • (1993) Science , vol.260 , Issue.5109 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 14
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Y. Ionov Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Nature 363 6429 1993 558 561
    • (1993) Nature , vol.363 , Issue.6429 , pp. 558-561
    • Ionov, Y.1
  • 15
    • 0027158031 scopus 로고
    • Clues to the pathogenesis of familial colorectal cancer
    • L.A. Aaltonen Clues to the pathogenesis of familial colorectal cancer Science 260 5109 1993 812 816
    • (1993) Science , vol.260 , Issue.5109 , pp. 812-816
    • Aaltonen, L.A.1
  • 16
    • 0032534069 scopus 로고    scopus 로고
    • Proceedings of the National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer
    • C.R. Boland, Proceedings of the National Cancer Institute Workshop on Microsatellite Instability for Cancer Detection and Familial Predisposition: Development of International Criteria for the Determination of Microsatellite Instability in Colorectal Cancer, Cancer Res. 58 (22) (1998) 5248-5257.
    • (1998) Cancer Res. , vol.58 , Issue.22 , pp. 5248-5257
    • Boland, C.R.1
  • 17
    • 0034642605 scopus 로고    scopus 로고
    • Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
    • R. Gryfe Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer New Engl. J. Med. 342 2 2000 69 77
    • (2000) New Engl. J. Med. , vol.342 , Issue.2 , pp. 69-77
    • Gryfe, R.1
  • 18
    • 0037408402 scopus 로고    scopus 로고
    • Phenotype of microsatellite unstable colorectal carcinomas: Well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instability
    • J.K. Greenson Phenotype of microsatellite unstable colorectal carcinomas: well-differentiated and focally mucinous tumors and the absence of dirty necrosis correlate with microsatellite instability Am. J. Surg. Pathol. 27 5 2003 563 570
    • (2003) Am. J. Surg. Pathol. , vol.27 , Issue.5 , pp. 563-570
    • Greenson, J.K.1
  • 19
    • 0034997971 scopus 로고    scopus 로고
    • Microsatellite instability and the clinicopathological features of sporadic colorectal cancer
    • R. Ward Microsatellite instability and the clinicopathological features of sporadic colorectal cancer Gut 48 6 2001 821 829
    • (2001) Gut , vol.48 , Issue.6 , pp. 821-829
    • Ward, R.1
  • 20
    • 0006171447 scopus 로고    scopus 로고
    • Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum
    • J.R. Jass Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum Gut 47 1 2000 43 49
    • (2000) Gut , vol.47 , Issue.1 , pp. 43-49
    • Jass, J.R.1
  • 21
    • 0036227426 scopus 로고    scopus 로고
    • Evolution of colorectal cancer: Change of pace and change of direction
    • J.R. Jass, J. Young, and B.A. Leggett Evolution of colorectal cancer: change of pace and change of direction J. Gastroenterol. Hepatol. 17 1 2002 17 26
    • (2002) J. Gastroenterol. Hepatol. , vol.17 , Issue.1 , pp. 17-26
    • Jass, J.R.1    Young, J.2    Leggett, B.A.3
  • 24
    • 0033405321 scopus 로고    scopus 로고
    • Towards a molecular classification of colorectal cancer
    • J.R. Jass Towards a molecular classification of colorectal cancer Int. J. Colorectal Dis. 14 4/5 1999 194 200
    • (1999) Int. J. Colorectal Dis. , vol.14 , Issue.45 , pp. 194-200
    • Jass, J.R.1
  • 25
    • 0029915034 scopus 로고    scopus 로고
    • Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome)
    • H.T. Lynch, T. Smyrk, and J.F. Lynch Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch Syndrome) Int. J. Cancer 69 1 1996 38 43
    • (1996) Int. J. Cancer , vol.69 , Issue.1 , pp. 38-43
    • Lynch, H.T.1    Smyrk, T.2    Lynch, J.F.3
  • 26
    • 0027263363 scopus 로고
    • Genetic mapping of a locus predisposing to human colorectal cancer
    • P. Peltomaki Genetic mapping of a locus predisposing to human colorectal cancer Science 260 5109 1993 810 812
    • (1993) Science , vol.260 , Issue.5109 , pp. 810-812
    • Peltomaki, P.1
  • 27
    • 16144368515 scopus 로고    scopus 로고
    • Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours
    • R.F. Souza Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours Nat. Genet. 14 3 1996 255 257
    • (1996) Nat. Genet. , vol.14 , Issue.3 , pp. 255-257
    • Souza, R.F.1
  • 28
    • 0028785603 scopus 로고
    • Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer
    • R. Parsons Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer Cancer Res. 55 23 1995 5548 5550
    • (1995) Cancer Res. , vol.55 , Issue.23 , pp. 5548-5550
    • Parsons, R.1
  • 29
    • 0029741089 scopus 로고    scopus 로고
    • Frameshift mutator mutations
    • S. Malkhosyan Frameshift mutator mutations Nature 382 6591 1996 499 500
    • (1996) Nature , vol.382 , Issue.6591 , pp. 499-500
    • Malkhosyan, S.1
  • 30
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • N. Rampino Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype Science 275 5302 1997 967 969
    • (1997) Science , vol.275 , Issue.5302 , pp. 967-969
    • Rampino, N.1
  • 31
    • 0028224645 scopus 로고
    • Mutator phenotypes in human colorectal carcinoma cell lines
    • N.P. Bhattacharyya Mutator phenotypes in human colorectal carcinoma cell lines Proc. Natl. Acad. Sci. U.S.A. 91 14 1994 6319 6323
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , Issue.14 , pp. 6319-6323
    • Bhattacharyya, N.P.1
  • 32
    • 0028887597 scopus 로고
    • Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer
    • J.R. Eshleman Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer Oncogene 10 1 1995 33 37
    • (1995) Oncogene , vol.10 , Issue.1 , pp. 33-37
    • Eshleman, J.R.1
  • 33
    • 18844464796 scopus 로고    scopus 로고
    • Colorectal cancer survival in hereditary nonpolyposis colorectal cancer
    • P. Watson Colorectal cancer survival in hereditary nonpolyposis colorectal cancer Cancer 83 1998 259 266
    • (1998) Cancer , vol.83 , pp. 259-266
    • Watson, P.1
  • 34
    • 0033063711 scopus 로고    scopus 로고
    • New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC Lynch syndrome) proposed by the International Collaborative Group on HNPCC
    • H.F. Vasen New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC Lynch syndrome) proposed by the International Collaborative Group on HNPCC Gastroenterology 116 6 1999 1453 1456
    • (1999) Gastroenterology , vol.116 , Issue.6 , pp. 1453-1456
    • Vasen, H.F.1
  • 35
    • 0032974189 scopus 로고    scopus 로고
    • Family history characteristics, tumor microsatellite instability and germline MSH2 and MLHl mutations in hereditary colorectal cancer
    • B.V. Bapat Family history characteristics, tumor microsatellite instability and germline MSH2 and MLHl mutations in hereditary colorectal cancer Hum. Genet. 104 2 1999 167 176
    • (1999) Hum. Genet. , vol.104 , Issue.2 , pp. 167-176
    • Bapat, B.V.1
  • 36
    • 2942569549 scopus 로고    scopus 로고
    • Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients
    • B. Liu Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients Nat. Med. 2 2 1996 169 174
    • (1996) Nat. Med. , vol.2 , Issue.2 , pp. 169-174
    • Liu, B.1
  • 37
    • 0035101436 scopus 로고    scopus 로고
    • DNA mismatch repair and cancer
    • P. Peltomaki DNA mismatch repair and cancer Mut. Res. 488 1 2001 77 85
    • (2001) Mut. Res. , vol.488 , Issue.1 , pp. 77-85
    • Peltomaki, P.1
  • 38
    • 0030948865 scopus 로고    scopus 로고
    • Mutations predisposing to hereditary nonpolyposis colorectal cancer
    • P. Peltomaki, and A. de la Chapelle Mutations predisposing to hereditary nonpolyposis colorectal cancer Adv. Cancer Res. 71 1997 93 119
    • (1997) Adv. Cancer Res. , vol.71 , pp. 93-119
    • Peltomaki, P.1    De La Chapelle, A.2
  • 39
    • 0030882381 scopus 로고    scopus 로고
    • Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study the International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer
    • P. Peltomaki, and H.F. Vasen Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer Gastroenterology 113 4 1997 1146 1158
    • (1997) Gastroenterology , vol.113 , Issue.4 , pp. 1146-1158
    • Peltomaki, P.1    Vasen, H.F.2
  • 40
    • 0032941343 scopus 로고    scopus 로고
    • Cancer risk in mutation carriers of DNA-mismatch-repair genes
    • M. Aarnio Cancer risk in mutation carriers of DNA-mismatch-repair genes Int. J. Cancer 81 2 1999 214 218
    • (1999) Int. J. Cancer , vol.81 , Issue.2 , pp. 214-218
    • Aarnio, M.1
  • 41
    • 0042563281 scopus 로고    scopus 로고
    • Genetic alterations and MSI status in primary, synchronous, and metachronous tumors in a family with hereditary nonpolysis colorectal cancer (HNPCC)
    • J.J. Gonzalez-Aguilera Genetic alterations and MSI status in primary, synchronous, and metachronous tumors in a family with hereditary nonpolysis colorectal cancer (HNPCC) Am. J. Clin. Oncol. 26 4 2003 386 391
    • (2003) Am. J. Clin. Oncol. , vol.26 , Issue.4 , pp. 386-391
    • Gonzalez-Aguilera, J.J.1
  • 42
    • 0027140481 scopus 로고
    • Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome
    • P. Peltomaki Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome Cancer Res. 53 24 1993 5853 5855
    • (1993) Cancer Res. , vol.53 , Issue.24 , pp. 5853-5855
    • Peltomaki, P.1
  • 43
    • 0034692454 scopus 로고    scopus 로고
    • Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases
    • D.J. Peel Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases J. Natl. Cancer Inst. 92 2000 1517 1522
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1517-1522
    • Peel, D.J.1
  • 44
    • 13144307115 scopus 로고    scopus 로고
    • Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
    • M.L. Veigl Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers Proc. Natl. Acad. Sci. U.S.A. 95 15 1998 8698 8702
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.15 , pp. 8698-8702
    • Veigl, M.L.1
  • 45
    • 0032146118 scopus 로고    scopus 로고
    • Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability
    • J.M. Cunningham Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability Cancer Res. 58 15 1998 3455 3460
    • (1998) Cancer Res. , vol.58 , Issue.15 , pp. 3455-3460
    • Cunningham, J.M.1
  • 46
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • M.F. Kane Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines Cancer Res. 57 5 1997 808 811
    • (1997) Cancer Res. , vol.57 , Issue.5 , pp. 808-811
    • Kane, M.F.1
  • 47
    • 13144266670 scopus 로고    scopus 로고
    • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
    • J.G. Herman Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Proc. Natl. Acad. Sci. U.S.A. 95 12 1998 6870 6875
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , Issue.12 , pp. 6870-6875
    • Herman, J.G.1
  • 48
    • 0032522658 scopus 로고    scopus 로고
    • Microsatellite instability in colorectal cancer: Different mutator phenotypes and the principal involvement of hMLH1
    • S.N. Thibodeau Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1 Cancer Res. 58 8 1998 1713 1718
    • (1998) Cancer Res. , vol.58 , Issue.8 , pp. 1713-1718
    • Thibodeau, S.N.1
  • 49
    • 12644274663 scopus 로고    scopus 로고
    • Alternative genetic pathways in colorectal carcinogenesis
    • S. Olschwang Alternative genetic pathways in colorectal carcinogenesis Proc. Natl. Acad. Sci. U.S.A. 94 22 1997 12122 12127
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , Issue.22 , pp. 12122-12127
    • Olschwang, S.1
  • 50
    • 0027136828 scopus 로고
    • Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
    • R.A. Lothe Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history Cancer Res. 53 24 1993 5849 5852
    • (1993) Cancer Res. , vol.53 , Issue.24 , pp. 5849-5852
    • Lothe, R.A.1
  • 51
    • 0032514366 scopus 로고    scopus 로고
    • Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53
    • J.R. Eshleman Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53 Oncogene 17 6 1998 719 725
    • (1998) Oncogene , vol.17 , Issue.6 , pp. 719-725
    • Eshleman, J.R.1
  • 52
    • 0034852772 scopus 로고    scopus 로고
    • Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level
    • W.S. Samowitz Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level Cancer Epidemiol. Biomark. Prev. 10 9 2001 917 923
    • (2001) Cancer Epidemiol. Biomark. Prev. , vol.10 , Issue.9 , pp. 917-923
    • Samowitz, W.S.1
  • 53
    • 0038002279 scopus 로고    scopus 로고
    • Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer
    • C.M. Ribic Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer New Engl. J. Med. 349 3 2003 247 257
    • (2003) New Engl. J. Med. , vol.349 , Issue.3 , pp. 247-257
    • Ribic, C.M.1
  • 54
    • 0041527133 scopus 로고    scopus 로고
    • Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers
    • S.Y. Jeong Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers Dis. Colon Rectum 46 8 2003 1069 1077
    • (2003) Dis. Colon Rectum , vol.46 , Issue.8 , pp. 1069-1077
    • Jeong, S.Y.1
  • 55
    • 0033831989 scopus 로고    scopus 로고
    • Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer
    • C.M. Wright Prognostic significance of extensive microsatellite instability in sporadic clinicopathological stage C colorectal cancer Br. J. Surg. 87 9 2000 1197 1202
    • (2000) Br. J. Surg. , vol.87 , Issue.9 , pp. 1197-1202
    • Wright, C.M.1
  • 56
    • 0035185894 scopus 로고    scopus 로고
    • Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings
    • J. Young Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings Am. J. Pathol. 159 6 2001 2107 2116
    • (2001) Am. J. Pathol. , vol.159 , Issue.6 , pp. 2107-2116
    • Young, J.1
  • 57
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • H. Kim Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences Am. J. Pathol. 145 1 1994 148 156
    • (1994) Am. J. Pathol. , vol.145 , Issue.1 , pp. 148-156
    • Kim, H.1
  • 58
    • 0343962992 scopus 로고    scopus 로고
    • Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis
    • A.E. Biemer-Huttmann Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis Clin. Cancer Res. 6 2000 1909 1916
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1909-1916
    • Biemer-Huttmann, A.E.1
  • 59
    • 0036224279 scopus 로고    scopus 로고
    • Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability
    • J.R. Jass Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability Eur. J. Cancer. 38 7 2002 858 866
    • (2002) Eur. J. Cancer. , vol.38 , Issue.7 , pp. 858-866
    • Jass, J.R.1
  • 60
    • 0000441155 scopus 로고    scopus 로고
    • DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutator pathway for colorectal cancer
    • H. Iino DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer J. Clin. Pathol. 52 1 1999 5 9
    • (1999) J. Clin. Pathol. , vol.52 , Issue.1 , pp. 5-9
    • Iino, H.1
  • 61
    • 0029991682 scopus 로고    scopus 로고
    • Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer
    • V.J. Bubb Microsatellite instability and the role of hMSH2 in sporadic colorectal cancer Oncogene 12 1996 2641 2649
    • (1996) Oncogene , vol.12 , pp. 2641-2649
    • Bubb, V.J.1
  • 62
    • 0033523204 scopus 로고    scopus 로고
    • Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers
    • K.C. Hailing Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers J. Natl. Cancer Inst. 91 15 1999 1295 1303
    • (1999) J. Natl. Cancer Inst. , vol.91 , Issue.15 , pp. 1295-1303
    • Hailing, K.C.1
  • 63
    • 0031891134 scopus 로고    scopus 로고
    • Prognostic significance of DNA replication errors in young patients with colorectal cancer
    • J.R. Lukish Prognostic significance of DNA replication errors in young patients with colorectal cancer Ann. Surg. 227 1 1998 51 56
    • (1998) Ann. Surg. , vol.227 , Issue.1 , pp. 51-56
    • Lukish, J.R.1
  • 64
    • 0032805226 scopus 로고    scopus 로고
    • Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma
    • J.M. Ko Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma Int. J. Cancer 84 4 1999 404 409
    • (1999) Int. J. Cancer , vol.84 , Issue.4 , pp. 404-409
    • Ko, J.M.1
  • 65
    • 0032815220 scopus 로고    scopus 로고
    • Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variables
    • J.T. Johannsdottir Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables Anticancer Res. 19 3A 1999 1821 1826
    • (1999) Anticancer Res. , vol.19 , Issue.3 , pp. 1821-1826
    • Johannsdottir, J.T.1
  • 66
    • 0033036918 scopus 로고    scopus 로고
    • Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers
    • L. Messerini Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers Hum. Pathol. 30 6 1999 629 634
    • (1999) Hum. Pathol. , vol.30 , Issue.6 , pp. 629-634
    • Messerini, L.1
  • 67
    • 0032867362 scopus 로고    scopus 로고
    • Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor
    • S. Salahshor Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor Br. J. Cancer 81 2 1999 190 193
    • (1999) Br. J. Cancer , vol.81 , Issue.2 , pp. 190-193
    • Salahshor, S.1
  • 68
    • 0034690610 scopus 로고    scopus 로고
    • Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer
    • H. Elsaleh Association of tumour site and sex with survival benefit from adjuvant chemotherapy in colorectal cancer Lancet 355 2000 1745 1750
    • (2000) Lancet , vol.355 , pp. 1745-1750
    • Elsaleh, H.1
  • 69
    • 0034895979 scopus 로고    scopus 로고
    • P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
    • H. Elsaleh P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma Clin. Cancer Res. 7 2001 1343 1349
    • (2001) Clin. Cancer Res. , vol.7 , pp. 1343-1349
    • Elsaleh, H.1
  • 70
    • 0033778049 scopus 로고    scopus 로고
    • Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy
    • A. Hemminki Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy Gastroenterology 119 2000 921 928
    • (2000) Gastroenterology , vol.119 , pp. 921-928
    • Hemminki, A.1
  • 71
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • T. Watanabe Molecular predictors of survival after adjuvant chemotherapy for colon cancer New Engl. J. Med. 344 16 2001 1196 1206
    • (2001) New Engl. J. Med. , vol.344 , Issue.16 , pp. 1196-1206
    • Watanabe, T.1
  • 72
    • 0032993145 scopus 로고    scopus 로고
    • Mismatch repair proficiency and in vitro response to 5-fluorouracil
    • J.M. Carethers Mismatch repair proficiency and in vitro response to 5-fluorouracil Gastroenterology 117 1 1999 123 131
    • (1999) Gastroenterology , vol.117 , Issue.1 , pp. 123-131
    • Carethers, J.M.1
  • 73
    • 0032956375 scopus 로고    scopus 로고
    • Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents
    • G. Colella Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents Br. J. Cancer 80 3/4 1999 338 343
    • (1999) Br. J. Cancer , vol.80 , Issue.34 , pp. 338-343
    • Colella, G.1
  • 74
    • 0031906084 scopus 로고    scopus 로고
    • The role of DNA mismatch repair in drug resistance
    • D. Fink, S. Aebi, and S.B. Howell The role of DNA mismatch repair in drug resistance Clin. Cancer Res. 4 1 1998 1 6
    • (1998) Clin. Cancer Res. , vol.4 , Issue.1 , pp. 1-6
    • Fink, D.1    Aebi, S.2    Howell, S.B.3
  • 75
    • 5544242524 scopus 로고    scopus 로고
    • Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis
    • M. Guidoboni Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis Am. J. Pathol. 159 1 2001 297 304
    • (2001) Am. J. Pathol. , vol.159 , Issue.1 , pp. 297-304
    • Guidoboni, M.1
  • 76
    • 0034622670 scopus 로고    scopus 로고
    • The effect of O-6-methylguanine DNA adducts on the adenosine nucleotide switch functions of hMSH2-hMSH6 and hMSH2-hMSH3
    • M. Berardini, A. Mazurek, and R. Fishel The effect of O-6-methylguanine DNA adducts on the adenosine nucleotide switch functions of hMSH2-hMSH6 and hMSH2-hMSH3 J. Biol. Chem. 275 2000 27851 27857
    • (2000) J. Biol. Chem. , vol.275 , pp. 27851-27857
    • Berardini, M.1    Mazurek, A.2    Fishel, R.3
  • 77
    • 0035117307 scopus 로고    scopus 로고
    • Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
    • V.L. Whitehall Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability Cancer Res. 61 3 2001 827 830
    • (2001) Cancer Res. , vol.61 , Issue.3 , pp. 827-830
    • Whitehall, V.L.1
  • 78
    • 0142232032 scopus 로고    scopus 로고
    • Value of histopathology in predicting microsatellite instability in hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer
    • J. Shia Value of histopathology in predicting microsatellite instability in hereditary nonpolyposis colorectal cancer and sporadic colorectal cancer Am. J. Surg. Pathol. 27 11 2003 1407 1417
    • (2003) Am. J. Surg. Pathol. , vol.27 , Issue.11 , pp. 1407-1417
    • Shia, J.1
  • 79
    • 0037168207 scopus 로고    scopus 로고
    • Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers
    • S.T. Yuen Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers Oncogene 21 49 2002 7585 7592
    • (2002) Oncogene , vol.21 , Issue.49 , pp. 7585-7592
    • Yuen, S.T.1
  • 80
    • 17144441735 scopus 로고    scopus 로고
    • Causes of microsatellite instability in colorectal tumors: Implications for hereditary non-polyposis colorectal cancer screening
    • U. Potocnik Causes of microsatellite instability in colorectal tumors: implications for hereditary non-polyposis colorectal cancer screening Cancer Genet Cytogenet. 126 2 2001 85 96
    • (2001) Cancer Genet Cytogenet. , vol.126 , Issue.2 , pp. 85-96
    • Potocnik, U.1


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