Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks

Neurobiology of Aging

Volumn 33, Issue 1, 2012, Pages 205.e1-205.e18

  Gleichmann, Marc ^a   Zhang, Yongqing ^a   Wood, William H ^a   Becker, Kevin G ^a   Mughal, Mohamed R ^a   Pazin, Michael J ^a   van Praag, Henriette ^a   Kobilo, Tali ^a   Zonderman, Alan B ^a   Troncoso, Juan C ^b   Markesbery, William R ^c   Mattson, Mark P ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Activity; Aging; Alzheimer's disease; Calcium; GABA; Homeostatic disinhibition; Interneuron; Synaptic scaling

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SOMATOSTATIN;

AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CALCIUM SIGNALING; CONTROLLED STUDY; DOWN REGULATION; ELECTRIC SHOCK; ENERGY CONSERVATION; ENVIRONMENTAL ENRICHMENT; GABAERGIC TRANSMISSION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LIPID METABOLISM; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 81355135326     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.08.012     Document Type: Article

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