메뉴 건너뛰기




Volumn 164, Issue 7, 2011, Pages 1793-1801

The SLC23 family of ascorbate transporters: Ensuring that you get and keep your daily dose of vitamin C

Author keywords

anion transport; oxidative stress; SVCT1; SVCT2

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ASCORBIC ACID; CARRIER PROTEIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN KINASE C; SODIUM DEPENDENT ASCORBIC ACID TRANSPORTER; SODIUM DEPENDENT ASCORBIC ACID TRANSPORTER 1; SODIUM DEPENDENT ASCORBIC ACID TRANSPORTER 2; UNCLASSIFIED DRUG;

EID: 81355134502     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01350.x     Document Type: Review
Times cited : (85)

References (104)
  • 2
    • 77950460185 scopus 로고    scopus 로고
    • Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice
    • Amano A, Aigaki T, Maruyama N, Ishigami A, (2010). Ascorbic acid depletion enhances expression of the sodium-dependent vitamin C transporters, SVCT1 and SVCT2, and uptake of ascorbic acid in livers of SMP30/GNL knockout mice. Arch Biochem Biophys 496: 38-44.
    • (2010) Arch Biochem Biophys , vol.496 , pp. 38-44
    • Amano, A.1    Aigaki, T.2    Maruyama, N.3    Ishigami, A.4
  • 3
    • 0142074875 scopus 로고    scopus 로고
    • Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells
    • DOI 10.1016/S0006-8993(03)03350-X
    • Angelow S, Haselbach M, Galla HJ, (2003). Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells. Brain Res 988: 105-113. (Pubitemid 37289499)
    • (2003) Brain Research , vol.988 , Issue.1-2 , pp. 105-113
    • Angelow, S.1    Haselbach, M.2    Galla, H.-J.3
  • 5
    • 0034658572 scopus 로고    scopus 로고
    • The vitamin C transporter SVCT2 is expressed by astrocytes in culture but not in situ
    • Berger UV, Hediger MA, (2000). The vitamin C transporter SVCT2 is expressed by astrocytes in culture but not in situ. Neuroreport 11: 1395-1399. (Pubitemid 30365474)
    • (2000) NeuroReport , vol.11 , Issue.7 , pp. 1395-1399
    • Berger, U.V.1    Hediger, M.A.2
  • 6
    • 0042731692 scopus 로고    scopus 로고
    • Effect of middle cerebral artery occlusion on mRNA expression for the sodium-coupled vitamin C transporter SVCT2 in rat brain
    • DOI 10.1046/j.1471-4159.2003.01891.x
    • Berger UV, Lu XC, Liu W, Tang Z, Slusher BS, Hediger MA, (2003). Effect of middle cerebral artery occlusion on mRNA expression for the sodium-coupled vitamin C transporter SVCT2 in rat brain. J Neurochem 86: 896-906. (Pubitemid 36988802)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.4 , pp. 896-906
    • Berger, U.V.1    Lu, X.-C.M.2    Liu, W.3    Tang, Z.4    Slusher, B.S.5    Hediger, M.A.6
  • 8
    • 33845626164 scopus 로고    scopus 로고
    • Expression and characterization of vitamin C transporter in the human trophoblast cell line HTR-8/SVneo: Effect of steroids, flavonoids and NSAIDs
    • DOI 10.1093/molehr/gal092
    • Biondi C, Pavan B, Dalpiaz A, Medici S, Lunghi L, Vesce F, (2007). Expression and characterization of vitamin C transporter in the human trophoblast cell line HTR-8/SVneo: effect of steroids, flavonoids and NSAIDs. Mol Hum Reprod 13: 77-83. (Pubitemid 44942727)
    • (2007) Molecular Human Reproduction , vol.13 , Issue.1 , pp. 77-83
    • Biondi, C.1    Pavan, B.2    Dalpiaz, A.3    Medici, S.4    Lunghi, L.5    Vesce, F.6
  • 10
    • 0025944599 scopus 로고
    • The pharmacological profile of glutamate-evoked ascorbic acid efflux measured by in vivo electrochemistry
    • Cammack J, Ghasemzadeh B, Adams RN, (1991). The pharmacological profile of glutamate-evoked ascorbic acid efflux measured by in vivo electrochemistry. Brain Res 565: 17-22.
    • (1991) Brain Res , vol.565 , pp. 17-22
    • Cammack, J.1    Ghasemzadeh, B.2    Adams, R.N.3
  • 11
    • 58149349823 scopus 로고    scopus 로고
    • The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids
    • Caprile T, Salazar K, Astuya A, Cisternas P, Silva-Alvarez C, Montecinos H, et al,. (2009). The Na+-dependent L-ascorbic acid transporter SVCT2 expressed in brainstem cells, neurons, and neuroblastoma cells is inhibited by flavonoids. J Neurochem 108: 563-577.
    • (2009) J Neurochem , vol.108 , pp. 563-577
    • Caprile, T.1    Salazar, K.2    Astuya, A.3    Cisternas, P.4    Silva-Alvarez, C.5    Montecinos, H.6
  • 14
    • 77951167788 scopus 로고    scopus 로고
    • Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice
    • Corpe CP, Tu H, Eck P, Wang J, Faulhaber-Walter R, Schnermann J, et al,. (2010). Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. J Clin Invest 120: 1069-1083.
    • (2010) J Clin Invest , vol.120 , pp. 1069-1083
    • Corpe, C.P.1    Tu, H.2    Eck, P.3    Wang, J.4    Faulhaber-Walter, R.5    Schnermann, J.6
  • 16
    • 0018672517 scopus 로고
    • Kinetics of 3-O-methyl-D-glucose transport in isolated rat hepatocytes
    • Craik JD, Elliott KRF, (1979). Kinetics of 3-O-methylglucose transport in isolated rat hepatocytes. Biochem J 182: 503-508. (Pubitemid 10224856)
    • (1979) Biochemical Journal , vol.182 , Issue.2 , pp. 503-508
    • Craik, J.D.1    Elliott, K.R.F.2
  • 19
    • 0032705918 scopus 로고    scopus 로고
    • Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2
    • DOI 10.1016/S0014-5793(99)01393-9, PII S0014579399013939
    • Daruwala R, Song J, Koh WS, Rumsey SC, Levine M, (1999). Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2. FEBS Lett 460: 480-484. (Pubitemid 29518424)
    • (1999) FEBS Letters , vol.460 , Issue.3 , pp. 480-484
    • Daruwala, R.1    Song, J.2    Koh, W.S.3    Rumsey, S.C.4    Levine, M.5
  • 20
    • 0035983275 scopus 로고    scopus 로고
    • Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol
    • DOI 10.1002/glia.10099
    • Daskalopoulos R, Korcok J, Tao L, Wilson JX, (2002). Accumulation of intracellular ascorbate from dehydroascorbic acid by astrocytes is decreased after oxidative stress and restored by propofol. Glia 39: 124-132. (Pubitemid 34817053)
    • (2002) GLIA , vol.39 , Issue.2 , pp. 124-132
    • Daskalopoulos, R.1    Korcok, J.2    Tao, L.3    Wilson, J.X.4
  • 22
    • 0034282217 scopus 로고    scopus 로고
    • Hemiketal formation of dehydroascorbic acid drives ascorbyl radical anion disproportionation
    • DiLabio GA, Wright JS, (2000). Hemiketal formation of dehydroascorbic acid drives ascorbyl radical anion disproportionation. Free Radic Biol Med 29: 480-485.
    • (2000) Free Radic Biol Med , vol.29 , pp. 480-485
    • Dilabio, G.A.1    Wright, J.S.2
  • 23
  • 24
    • 4544281382 scopus 로고    scopus 로고
    • Comparison of the genomic structure and variation in the two human sodium-dependent Vitamin C transporters, SLC23A1 and SLC23A2
    • DOI 10.1007/s00439-004-1167-x
    • Eck P, Erichsen HC, Taylor JG, Yeager M, Hughes AL, Levine M, et al,. (2004). Comparison of the genomic structure and variation in the two human sodium-dependent vitamin C transporters, SLC23A1 and SLC23A2. Hum Genet 115: 285-294. (Pubitemid 39247869)
    • (2004) Human Genetics , vol.115 , Issue.4 , pp. 285-294
    • Eck, P.1    Erichsen, H.C.2    Taylor, J.G.3    Yeager, M.4    Hughes, A.L.5    Levine, M.6    Chanock, S.J.7
  • 25
    • 38149035238 scopus 로고    scopus 로고
    • Genomic and functional analysis of the sodium-dependent vitamin C transporter SLC23A1-SVCT1
    • Eck P, Erichsen HC, Taylor JG, Corpe C, Chanock SJ, Levine M, (2007). Genomic and functional analysis of the sodium-dependent vitamin C transporter SLC23A1-SVCT1. Genes Nutr 2: 143-145.
    • (2007) Genes Nutr , vol.2 , pp. 143-145
    • Eck, P.1    Erichsen, H.C.2    Taylor, J.G.3    Corpe, C.4    Chanock, S.J.5    Levine, M.6
  • 27
    • 51849117309 scopus 로고    scopus 로고
    • Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma
    • Erichsen HC, Peters U, Eck P, Welch R, Schoen RE, Yeager M, et al,. (2008). Genetic variation in sodium-dependent vitamin C transporters SLC23A1 and SLC23A2 and risk of advanced colorectal adenoma. Nutr Cancer 60: 652-659.
    • (2008) Nutr Cancer , vol.60 , pp. 652-659
    • Erichsen, H.C.1    Peters, U.2    Eck, P.3    Welch, R.4    Schoen, R.E.5    Yeager, M.6
  • 28
    • 0019945384 scopus 로고
    • The distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration
    • DOI 10.1079/BJN19820059
    • Evans RM, Currie L, Campbell A, (1982). The distribution of ascorbic acid between various cellular components of blood, in normal individuals, and its relation to the plasma concentration. Br J Nutr 47: 473-482. (Pubitemid 12016758)
    • (1982) British Journal of Nutrition , vol.47 , Issue.3 , pp. 473-482
    • Evans, R.M.1    Currie, L.2    Campbell, A.3
  • 30
    • 0034888127 scopus 로고    scopus 로고
    • Dexamethasone induces sodium-dependant vitamin C transporter in a mouse osteoblastic cell line MC3T3-E1
    • Fujita I, Hirano J, Itoh N, Nakanishi T, Tanaka K, (2001). Dexamethasone induces sodium-dependant vitamin C transporter in a mouse osteoblastic cell line MC3T3-E1. Br J Nutr 86: 145-149. (Pubitemid 32780618)
    • (2001) British Journal of Nutrition , vol.86 , Issue.2 , pp. 145-149
    • Fujita, I.1    Hirano, J.2    Itoh, N.3    Nakanishi, T.4    Tanaka, K.5
  • 31
    • 0030773936 scopus 로고    scopus 로고
    • Enhanced protection against peroxidation-induced mortality of aortic endothelial cells by ascorbic Acid-2-O-phosphate abundantly accumulated in the cell as the dephosphorylated form
    • Fujiwara M, Nagao N, Monden K, Misumi M, Kageyama K, Yamamoto K, et al,. (1997). Enhanced protection against peroxidation-induced mortality of aortic endothelial cells by ascorbic acid-2-O-phosphate abundantly accumulated in the cell as the dephosphorylated form. Free Radic Res 27: 97-104. (Pubitemid 27390252)
    • (1997) Free Radical Research , vol.27 , Issue.1 , pp. 97-104
    • Fujiwara, M.1    Nagao, N.2    Monden, K.3    Misumi, M.4    Kageyama, K.5    Yamamoto, K.6    Miwa, N.7
  • 34
    • 60449102448 scopus 로고    scopus 로고
    • Vitamin C function in the brain: Vital role of the ascorbate transporter (SVCT2)
    • Harrison FE, May JM, (2009). Vitamin C function in the brain: vital role of the ascorbate transporter (SVCT2). Free Radic Biol Med 45: 719-730.
    • (2009) Free Radic Biol Med , vol.45 , pp. 719-730
    • Harrison, F.E.1    May, J.M.2
  • 35
    • 77955092602 scopus 로고    scopus 로고
    • Low vitamin C and increased oxidative stress cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2
    • Harrison FE, Dawes SM, Meredith ME, Babaev VR, Li L, May JM, (2010). Low vitamin C and increased oxidative stress cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2. Free Radic Biol Med 49: 821-829.
    • (2010) Free Radic Biol Med , vol.49 , pp. 821-829
    • Harrison, F.E.1    Dawes, S.M.2    Meredith, M.E.3    Babaev, V.R.4    Li, L.5    May, J.M.6
  • 36
    • 0027029575 scopus 로고
    • Increase in the activity of alkaline phosphatase by L-ascorbic acid 2-phosphate in a human osteoblast cell line, HuO-3N1
    • Hitomi K, Torii Y, Tsukagoshi N, (1992). Increase in the activity of alkaline phosphatase by L-ascorbic acid 2-phosphate in a human osteoblast cell line, HuO-3N1. J Nutr Sci Vitaminol (Tokyo) 38: 535-544.
    • (1992) J Nutr Sci Vitaminol (Tokyo) , vol.38 , pp. 535-544
    • Hitomi, K.1    Torii, Y.2    Tsukagoshi, N.3
  • 37
    • 0033166148 scopus 로고    scopus 로고
    • A human nucleobase transporter-like cDNA (SLC23A1): Member of a transporter family conserved from bacteria to mammals
    • DOI 10.1006/geno.1999.5847
    • Hogue DL, Ling V, (1999). A human nucleobase transporter-like cDNA (SLC23A1): member of a transporter family conserved from bacteria to mammals. Genomics 59: 18-23. (Pubitemid 29339868)
    • (1999) Genomics , vol.59 , Issue.1 , pp. 18-23
    • Hogue, D.L.1    Ling, V.2
  • 39
    • 0018827418 scopus 로고
    • Subcellular distribution of ascorbate in bovine adrenal medulla. Evidence for accumulation in chromaffin granules against a concentration gradient
    • Ingebretsen OC, Terland O, Flatmark T, (1980). Subcellular distribution of ascorbate in bovine adrenal medulla. Evidence for accumulation in chromaffin granules against a concentration gradient. Biochim Biophys Acta 628: 182-189. (Pubitemid 10097242)
    • (1980) Biochimica et Biophysica Acta , vol.628 , Issue.2 , pp. 182-189
    • Ingebretsen, O.C.1    Terland, O.2    Flatmark, T.3
  • 41
    • 33847066356 scopus 로고    scopus 로고
    • Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane
    • Kang JS, Kim HN, Jung DJ, Kim JE, Mun GH, Kim YS, et al,. (2007). Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. J Invest Dermatol 127: 698-706.
    • (2007) J Invest Dermatol , vol.127 , pp. 698-706
    • Kang, J.S.1    Kim, H.N.2    Jung, D.J.3    Kim, J.E.4    Mun, G.H.5    Kim, Y.S.6
  • 42
    • 0142075332 scopus 로고    scopus 로고
    • Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells
    • DOI 10.1016/S0891-5849(03)00326-5
    • Kashino G, Kodama S, Nakayama Y, Suzuki K, Fukase K, Goto M, et al,. (2003). Relief of oxidative stress by ascorbic acid delays cellular senescence of normal human and Werner syndrome fibroblast cells. Free Radic Biol Med 35: 438-443. (Pubitemid 37289173)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.4 , pp. 438-443
    • Kashino, G.1    Kodama, S.2    Nakayama, Y.3    Suzuki, K.4    Fukase, K.5    Goto, M.6    Watanabe, M.7
  • 43
    • 70350719350 scopus 로고    scopus 로고
    • 6-Deoxy-6-[131I]iodo-L-ascorbic acid for the in vivo study of ascorbate: Autoradiography, biodistribution in normal and hypolipidemic rats, and in tumor-bearing nude mice
    • Kim J, Yamamoto F, Gondo S, Yanase T, Mukai T, Maeda M, (2009). 6-Deoxy-6-[131I]iodo-L-ascorbic acid for the in vivo study of ascorbate: autoradiography, biodistribution in normal and hypolipidemic rats, and in tumor-bearing nude mice. Biol Pharm Bull 32: 1906-1911.
    • (2009) Biol Pharm Bull , vol.32 , pp. 1906-1911
    • Kim, J.1    Yamamoto, F.2    Gondo, S.3    Yanase, T.4    Mukai, T.5    Maeda, M.6
  • 44
    • 0034722124 scopus 로고    scopus 로고
    • Sodium-ascorbate cotransport controls intracellular ascorbate concentration in primary astrocyte cultures expressing the SVCT2 transporter
    • Korcok J, Yan R, Siushansian R, Dixon SJ, Wilson JX, (2000). Sodium-ascorbate cotransport controls intracellular ascorbate concentration in primary astrocyte cultures expressing the SVCT2 transporter. Brain Res 881: 144-151.
    • (2000) Brain Res , vol.881 , pp. 144-151
    • Korcok, J.1    Yan, R.2    Siushansian, R.3    Dixon, S.J.4    Wilson, J.X.5
  • 45
    • 0013852562 scopus 로고
    • Inhibition by phloretin and phlorizin derivatives of sugar transport in different cells
    • Kotyk A, Kolinska J, Veres K, Szammer J, (1965). Inhibition by phloretin and phlorizin derivatives of sugar transport in different cells. Biochem Z 342: 129-138.
    • (1965) Biochem Z , vol.342 , pp. 129-138
    • Kotyk, A.1    Kolinska, J.2    Veres, K.3    Szammer, J.4
  • 46
    • 0020434998 scopus 로고
    • Tissue levels of ascorbic acid during rat gestation
    • Kratzing CC, Kelly JD, (1982). Tissue levels of ascorbic acid during rat gestation. Int J Vitam Nutr Res 52: 326-332.
    • (1982) Int J Vitam Nutr Res , vol.52 , pp. 326-332
    • Kratzing, C.C.1    Kelly, J.D.2
  • 47
    • 0002383467 scopus 로고
    • Sugar transport in the red blood cell: Structure-activity relationships in substrates and antagonists
    • LeFevre PG, (1961). Sugar transport in the red blood cell: structure-activity relationships in substrates and antagonists. Pharmacol Rev 13: 39-70.
    • (1961) Pharmacol Rev , vol.13 , pp. 39-70
    • Lefevre, P.G.1
  • 48
    • 0038578532 scopus 로고    scopus 로고
    • Ascorbic acid spares α-tocopherol and decreases lipid peroxidation in neuronal cells
    • DOI 10.1016/S0006-291X(03)00836-2
    • Li X, Huang J, May JM, (2003). Ascorbic acid spares alpha-tocopherol and decreases lipid peroxidation in neuronal cells. Biochem Biophys Res Commun 305: 656-661. (Pubitemid 36579281)
    • (2003) Biochemical and Biophysical Research Communications , vol.305 , Issue.3 , pp. 656-661
    • Li, X.1    Huang, J.2    May, J.M.3
  • 51
    • 1842453111 scopus 로고    scopus 로고
    • A Human Sodium-Dependent Vitamin C Transporter 2 Isoform Acts as a Dominant-Negative Inhibitor of Ascorbic Acid Transport
    • DOI 10.1128/MCB.24.8.3150-3156.2004
    • Lutsenko EA, Carcamo JM, Golde DW, (2004). A human sodium-dependent vitamin C transporter 2 isoform acts as a dominant-negative inhibitor of ascorbic acid transport. Mol Cell Biol 24: 3150-3156. (Pubitemid 38452061)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.8 , pp. 3150-3156
    • Lutsenko, E.A.1    Carcamo, J.M.2    Golde, D.W.3
  • 54
    • 0034190373 scopus 로고    scopus 로고
    • How does ascorbic acid prevent endothelial dysfunction?
    • DOI 10.1016/S0891-5849(00)00269-0, PII S0891584900002690
    • May JM, (2000). How does ascorbic acid prevent endothelial dysfunction? Free Radic Biol Med 28: 1421-1429. (Pubitemid 30621484)
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.9 , pp. 1421-1429
    • May, J.M.1
  • 55
    • 15844414782 scopus 로고    scopus 로고
    • Ascorbate recycling
    • Asard H. May J.M. Smirnoff N. (eds). Bios Scientific Publishers: London
    • May JM, Asard H, (2004). Ascorbate recycling. In:, Asard H, May JM, Smirnoff N, (eds). Vitamin C. Functions and Biochemistry in Animals and Plants. Bios Scientific Publishers: London, pp. 139-158.
    • (2004) Vitamin C. Functions and Biochemistry in Animals and Plants , pp. 139-158
    • May, J.M.1    Asard, H.2
  • 56
    • 33645193994 scopus 로고    scopus 로고
    • Redox regulation of ascorbic acid transport: Role of transporter and intracellular sulfhydryls
    • May JM, Qu ZC, (2004). Redox regulation of ascorbic acid transport: role of transporter and intracellular sulfhydryls. Biofactors 20: 199-211.
    • (2004) Biofactors , vol.20 , pp. 199-211
    • May, J.M.1    Qu, Z.C.2
  • 57
    • 27544469136 scopus 로고    scopus 로고
    • Macrophage uptake and recycling of ascorbic acid: Response to activation by lipopolysaccharide
    • DOI 10.1016/j.freeradbiomed.2005.07.006, PII S089158490500393X
    • May JM, Huang J, Qu ZC, (2005). Macrophage uptake and recycling of ascorbic acid: response to activation by lipopolysaccharide. Free Radic Biol Med 39: 1449-1459. (Pubitemid 41547225)
    • (2005) Free Radical Biology and Medicine , vol.39 , Issue.11 , pp. 1449-1459
    • May, J.M.1    Huang, J.2    Qu, Z.-C.3
  • 59
    • 67650077095 scopus 로고    scopus 로고
    • Transfer of ascorbic acid across the vascular endothelium: Mechanism and self-regulation
    • May JM, Qu ZC, Qiao H, (2009). Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation. Am J Physiol Cell Physiol 297: C169-C178.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • May, J.M.1    Qu, Z.C.2    Qiao, H.3
  • 60
    • 0037330979 scopus 로고    scopus 로고
    • Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes
    • DOI 10.1016/S0003-9861(02)00678-1, PII S0003986102006781
    • Michels AJ, Joisher N, Hagen TM, (2003). Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes. Arch Biochem Biophys 410: 112-120. (Pubitemid 36268802)
    • (2003) Archives of Biochemistry and Biophysics , vol.410 , Issue.1 , pp. 112-120
    • Michels, A.J.1    Joisher, N.2    Hagen, T.M.3
  • 61
    • 0030098278 scopus 로고    scopus 로고
    • Inhibitory action of palytoxin on ascorbic acid transport into cultured bovine adrenal chromaffin cells
    • Morita K, Teraoka K, Oka M, Levine M, (1996). Inhibitory action of palytoxin on ascorbic acid transport into cultured bovine adrenal chromaffin cells. J Pharmacol Exp Ther 276: 996-1001. (Pubitemid 126660574)
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.276 , Issue.3 , pp. 996-1001
    • Morita, K.1    Teraoka, K.2    Oka, M.3    Levine, M.4
  • 62
    • 33645302927 scopus 로고    scopus 로고
    • Immunohistochemical study of the distribution of sodium-dependent vitamin C transporters in adult rat brain
    • Mun GH, Kim MJ, Lee JH, Kim HJ, Chung YH, Chung YB, et al,. (2006). Immunohistochemical study of the distribution of sodium-dependent vitamin C transporters in adult rat brain. J Neurosci Res 83: 919-928.
    • (2006) J Neurosci Res , vol.83 , pp. 919-928
    • Mun, G.H.1    Kim, M.J.2    Lee, J.H.3    Kim, H.J.4    Chung, Y.H.5    Chung, Y.B.6
  • 65
    • 0030463882 scopus 로고    scopus 로고
    • L-ascorbic acid regulates growth and metabolism of renal cells: Improvements in cell culture
    • Nowak G, Schnellmann RG, (1996). L-ascorbic acid regulates growth and metabolism of renal cells: improvements in cell culture. Am J Physiol 271: C2072-C2080.
    • (1996) Am J Physiol , vol.271
    • Nowak, G.1    Schnellmann, R.G.2
  • 67
    • 0018716601 scopus 로고
    • Uptake of L-ascorbic acid and L-dehydroascorbic acid by human erythrocytes and HeLa cells
    • Okamura M, (1979). Uptake of L-ascorbic acid and L-dehydroascorbic acid by human erythrocytes and HeLa cells. J Nutr Sci Vitaminol (Tokyo) 25: 269-279. (Pubitemid 10217868)
    • (1979) Journal of Nutritional Science and Vitaminology , vol.25 , Issue.4 , pp. 269-279
    • Okamura, M.1
  • 68
    • 0021689258 scopus 로고
    • Voltammetrically monitored brain ascorbate as an index of excitatory amino acid release in the unrestrained rat
    • DOI 10.1016/0304-3940(84)90166-6
    • O'Neill RD, Fillenz M, Sundstrom L, Rawlins JN, (1984). Voltammetrically monitored brain ascorbate as an index of excitatory amino acid release in the unrestrained rat. Neurosci Lett 52: 227-233. (Pubitemid 15186490)
    • (1984) Neuroscience Letters , vol.52 , Issue.3 , pp. 227-233
    • O'Neill, R.D.1    Fillenz, M.2    Sundstrom, L.3    Rawlins, J.N.P.4
  • 71
    • 18744409322 scopus 로고    scopus 로고
    • Ascorbyl-6-palmitate is not ascorbic acid
    • DOI 10.1046/j.1523-1747.2002.19530.x
    • Pinnell SR, (2002). Ascorbyl-6-palmitate is not ascorbic acid. J Invest Dermatol 119: 991. (Pubitemid 35430475)
    • (2002) Journal of Investigative Dermatology , vol.119 , Issue.5 , pp. 991
    • Pinnell, S.R.1
  • 72
    • 43049086976 scopus 로고    scopus 로고
    • Development of ascorbate transport in brain capillary endothelial cells in culture
    • Qiao H, May JM, (2008). Development of ascorbate transport in brain capillary endothelial cells in culture. Brain Res 1208: 79-86.
    • (2008) Brain Res , vol.1208 , pp. 79-86
    • Qiao, H.1    May, J.M.2
  • 73
    • 63049084833 scopus 로고    scopus 로고
    • Macrophage differentiation increases expression of the ascorbate transporter (SVCT2)
    • Qiao H, May JM, (2009). Macrophage differentiation increases expression of the ascorbate transporter (SVCT2). Free Radic Biol Med 46: 1221-1232.
    • (2009) Free Radic Biol Med , vol.46 , pp. 1221-1232
    • Qiao, H.1    May, J.M.2
  • 74
    • 34147223962 scopus 로고    scopus 로고
    • Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity
    • DOI 10.1002/jnr.21204
    • Qiu S, Li L, Weeber EJ, May JM, (2007). Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity. J Neurosci Res 85: 1046-1056. (Pubitemid 46580345)
    • (2007) Journal of Neuroscience Research , vol.85 , Issue.5 , pp. 1046-1056
    • Qiu, S.1    Li, Y.2    Weeber, E.J.3    May, J.M.4
  • 77
    • 0028142763 scopus 로고
    • A vitamin as neuromodulator: Ascorbate release into the extracellular fluid of the brain regulates dopaminergic and glutamatergic transmission
    • DOI 10.1016/0301-0082(94)90052-3
    • Rebec GV, Pierce RC, (1994). A vitamin as neuromodulator: ascorbate release into the extracellular fluid of the brain regulates dopaminergic and glutamatergic transmission. Prog Neurobiol 43: 537-565. (Pubitemid 24274418)
    • (1994) Progress in Neurobiology , vol.43 , Issue.6 , pp. 537-565
    • Rebec, G.V.1    Pierce, R.C.2
  • 78
    • 0343131929 scopus 로고    scopus 로고
    • Differential compartmentalization of brain ascorbate and glutathione between neurons and glia
    • DOI 10.1016/S0306-4522(97)00347-3, PII S0306452297003473
    • Rice ME, Russo-Menna I, (1998). Differential compartmentalization of brain ascorbate and glutathione between neurons and glia. Neuroscience 82: 1213-1223. (Pubitemid 27502062)
    • (1998) Neuroscience , vol.82 , Issue.4 , pp. 1213-1223
    • Rice, M.E.1    Russo-Menna, I.2
  • 79
    • 0023878633 scopus 로고
    • Transport of ascorbic acid and other water-soluble vitamins
    • Rose RC, (1988). Transport of ascorbic acid and other water-soluble vitamins. Biochim Biophys Acta 947: 335-366.
    • (1988) Biochim Biophys Acta , vol.947 , pp. 335-366
    • Rose, R.C.1
  • 80
    • 0012369987 scopus 로고    scopus 로고
    • Ascorbate 6-palmitate protects human erythrocytes from oxidative damage
    • Ross D, Mendiratta S, Qu ZC, Cobb CE, May JM, (1999). Ascorbate 6-palmitate protects human erythrocytes from oxidative damage. Free Radic Biol Med 26: 81-89.
    • (1999) Free Radic Biol Med , vol.26 , pp. 81-89
    • Ross, D.1    Mendiratta, S.2    Qu, Z.C.3    Cobb, C.E.4    May, J.M.5
  • 81
    • 33144455402 scopus 로고    scopus 로고
    • +-dependent vitamin C transporter 2, SLC23A2, in human vascular smooth muscle cells
    • DOI 10.1016/j.bbaexp.2005.11.002, PII S0167478105002733
    • Rubin SA, Dey S, Reidling JC, (2005). Functional analysis of two regulatory regions of the human Na+ -dependent vitamin C transporter 2, SLC23A2, in human vascular smooth muscle cells. Biochim Biophys Acta 1732: 76-81. (Pubitemid 43267307)
    • (2005) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1732 , Issue.1-3 , pp. 76-81
    • Rubin, S.A.1    Dey, S.2    Reidling, J.C.3
  • 85
    • 42449122220 scopus 로고    scopus 로고
    • SVCT1 and SVCT2: Key proteins for vitamin C uptake
    • DOI 10.1007/s00726-007-0555-7
    • Savini I, Rossi A, Pierro C, Avigliano L, Catani MV, (2008). SVCT1 and SVCT2: key proteins for vitamin C uptake. Amino Acids 34: 347-355. (Pubitemid 351569766)
    • (2008) Amino Acids , vol.34 , Issue.3 , pp. 347-355
    • Savini, I.1    Rossi, A.2    Pierro, C.3    Avigliano, L.4    Catani, M.V.5
  • 86
    • 0030929914 scopus 로고    scopus 로고
    • Cerebral astrocytes transport ascorbic acid and dehydroascorbic acid through distinct mechanisms regulated by cyclic AMP
    • Siushansian R, Tao L, Dixon SJ, Wilson JX, (1997). Cerebral astrocytes transport ascorbic acid and dehydroascorbic acid through distinct mechanisms regulated by cyclic AMP. J Neurochem 68: 2378-2385. (Pubitemid 27218158)
    • (1997) Journal of Neurochemistry , vol.68 , Issue.6 , pp. 2378-2385
    • Siushansian, R.1    Tao, L.2    Dixon, S.J.3    Wilson, J.X.4
  • 87
    • 0037013196 scopus 로고    scopus 로고
    • Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose
    • DOI 10.1074/jbc.M110496200
    • Song J, Kwon O, Chen SL, Daruwala R, Eck P, Park JB, et al,. (2002). Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and glucose. J Biol Chem 277: 15252-15260. (Pubitemid 34967785)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.18 , pp. 15252-15260
    • Song, J.1    Kwon, O.2    Chen, S.3    Daruwala, R.4    Eck, P.5    Park, J.B.6    Levine, M.7
  • 89
    • 0015831449 scopus 로고
    • Ascorbic acid homeostasis in the central nervous system
    • Spector R, Lorenzo AV, (1973). Ascorbic acid homeostasis in the central nervous system. Am J Physiol 225: 757-763.
    • (1973) Am J Physiol , vol.225 , pp. 757-763
    • Spector, R.1    Lorenzo, A.V.2
  • 90
    • 0034265993 scopus 로고    scopus 로고
    • Mapping of the human genes (SLC23A2 and SLC23A1) coding for vitamin C transporters 1 and 2 (SVCT1 and SVCT2) to 5q23 and 20p12, respectively
    • Stratakis CA, Taymans SE, Daruwala R, Song J, Levine M, (2000). Mapping of the human genes (SLC23A2 and SLC23A1) coding for vitamin C transporters 1 and 2 (SVCT1 and SVCT2) to 5q23 and 20p12, respectively. J Med Genet 37: E20.
    • (2000) J Med Genet , vol.37
    • Stratakis, C.A.1    Taymans, S.E.2    Daruwala, R.3    Song, J.4    Levine, M.5
  • 91
    • 1242317668 scopus 로고    scopus 로고
    • Sodium-dependent ascorbic acid transporter family SLC23
    • DOI 10.1007/s00424-003-1104-1, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
    • Takanaga H, Mackenzie B, Hediger MA, (2004). Sodium-dependent ascorbic acid transporter family SLC23. Pflugers Arch 447: 677-682. (Pubitemid 38241453)
    • (2004) Pflugers Archiv European Journal of Physiology , vol.447 , Issue.5 , pp. 677-682
    • Takanaga, H.1    Mackenzie, B.2    Hediger, M.A.3
  • 93
    • 0033567402 scopus 로고    scopus 로고
    • Efflux of hepatic ascorbate: A potential contributor to the maintenance of plasma vitamin C
    • DOI 10.1042/0264-6021:3420049
    • Upston JM, Karjalainen A, Bygrave FL, Stocker R, (1999). Efflux of hepatic ascorbate: a potential contributor to the maintenance of plasma vitamin C. Biochem J 342: 49-56. (Pubitemid 29410848)
    • (1999) Biochemical Journal , vol.342 , Issue.1 , pp. 49-56
    • Upston, J.M.1    Karjalainen, A.2    Bygrave, F.L.3    Stocker, R.4
  • 94
    • 0027302594 scopus 로고
    • Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid
    • DOI 10.1038/364079a0
    • Vera JC, Rivas CI, Fischbarg J, Golde DW, (1993). Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Nature 364: 79-82. (Pubitemid 23233461)
    • (1993) Nature , vol.364 , Issue.6432 , pp. 79-82
    • Vera, J.C.1    Rivas, C.I.2    Fischbarg, J.3    Golde, D.W.4
  • 97
    • 0025082330 scopus 로고
    • Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity
    • Wells WW, Xu DP, Yang YF, Rocque PA, (1990). Mammalian thioltransferase (glutaredoxin) and protein disulfide isomerase have dehydroascorbate reductase activity. J Biol Chem 265: 15361-15364.
    • (1990) J Biol Chem , vol.265 , pp. 15361-15364
    • Wells, W.W.1    Xu, D.P.2    Yang, Y.F.3    Rocque, P.A.4
  • 98
    • 0024462487 scopus 로고
    • Ascorbic acid uptake by a high-affinity sodium-dependent mechanism in cultured rat astrocytes
    • Wilson JX, (1989). Ascorbic acid uptake by a high-affinity sodium-dependent mechanism in cultured rat astrocytes. J Neurochem 53: 1064-1071. (Pubitemid 19238470)
    • (1989) Journal of Neurochemistry , vol.53 , Issue.4 , pp. 1064-1071
    • Wilson, J.X.1
  • 99
    • 23944482400 scopus 로고    scopus 로고
    • Regulation of vitamin C transport
    • DOI 10.1146/annurev.nutr.25.050304.092647
    • Wilson JX, (2005). Regulation of vitamin C transport. Annu Rev Nutr 25: 105-125. (Pubitemid 41208996)
    • (2005) Annual Review of Nutrition , vol.25 , pp. 105-125
    • Wilson, J.X.1
  • 100
    • 25144503255 scopus 로고    scopus 로고
    • Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes
    • DOI 10.1016/j.freeradbiomed.2005.05.020, PII S0891584905003035
    • Wilson JX, Dragan M, (2005). Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes. Free Radic Biol Med 39: 990-998. (Pubitemid 41356591)
    • (2005) Free Radical Biology and Medicine , vol.39 , Issue.8 , pp. 990-998
    • Wilson, J.X.1    Dragan, M.2
  • 101
    • 0038697965 scopus 로고    scopus 로고
    • Requirement of calcium and phosphate ions in expression of sodium-dependent vitamin C transporter 2 and osteopontin in MC3T3-E1 osteoblastic cells
    • DOI 10.1016/S0167-4889(03)00065-X
    • Wu X, Itoh N, Taniguchi T, Nakanishi T, Tanaka K, (2003a). Requirement of calcium and phosphate ions in expression of sodium-dependent vitamin C transporter 2 and osteopontin in MC3T3-E1 osteoblastic cells. Biochim Biophys Acta 1641: 65-70. (Pubitemid 36638710)
    • (2003) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1641 , Issue.1 , pp. 65-70
    • Wu, X.1    Itoh, N.2    Taniguchi, T.3    Nakanishi, T.4    Tanaka, K.5
  • 102
    • 0242610816 scopus 로고    scopus 로고
    • Zinc-induced sodium-dependent vitamin C transporter 2 expression: Potent roles in osteoblast differentiation
    • DOI 10.1016/j.abb.2003.09.013
    • Wu X, Itoh N, Taniguchi T, Nakanishi T, Tatsu Y, Yumoto N, et al,. (2003b). Zinc-induced sodium-dependent vitamin C transporter 2 expression: potent roles in osteoblast differentiation. Arch Biochem Biophys 420: 114-120. (Pubitemid 37406663)
    • (2003) Archives of Biochemistry and Biophysics , vol.420 , Issue.1 , pp. 114-120
    • Wu, X.1    Itoh, N.2    Taniguchi, T.3    Nakanishi, T.4    Tatsu, Y.5    Yumoto, N.6    Tanaka, K.7
  • 103
    • 1942420158 scopus 로고    scopus 로고
    • Stimulation of differentiation in sodium-dependent vitamin C transporter 2 overexpressing MC3T3-E1 osteoblasts
    • DOI 10.1016/j.bbrc.2004.03.158, PII S0006291X04006643
    • Wu XM, Itoh N, Taniguchi T, Hirano J, Nakanishi T, Tanaka K, (2004). Stimulation of differentiation in sodium-dependent vitamin C transporter 2 overexpressing MC3T3-E1 osteoblasts. Biochem Biophys Res Commun 317: 1159-1164. (Pubitemid 38496432)
    • (2004) Biochemical and Biophysical Research Communications , vol.317 , Issue.4 , pp. 1159-1164
    • Wu, X.1    Itoh, N.2    Taniguchi, T.3    Hirano, J.4    Nakanishi, T.5    Tanaka, K.6
  • 104
    • 34548801436 scopus 로고    scopus 로고
    • Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells
    • DOI 10.1038/sj.cdd.4402190, PII 4402190
    • Wu X, Zeng LH, Taniguchi T, Xie QM, (2007). Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. Cell Death Differ 14: 1792-1801. (Pubitemid 47423646)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.10 , pp. 1792-1801
    • Wu, X.1    Zeng, L.-H.2    Taniguchi, T.3    Xie, Q.-M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.