Ascorbate 6-palmitate protects human erythrocytes from oxidative damage

Free Radical Biology and Medicine

Volumn 26, Issue 1-2, 1999, Pages 81-89

  Ross, Daniel ^a   Mendiratta, Shalu ^a   Qu, Zhi Chao ^a   Cobb, Charles E ^a   May, James M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ascorbate 6 palmitate; Cis Parinaric acid; Ferricyanide; Free radical; Oxidant stress; Tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ASCORBATE 6 PALMITATE; ASCORBIC ACID; ASCORBIC ACID DERIVATIVE; DEHYDROASCORBIC ACID; FERRICYANIDE; FREE RADICAL; PARINARIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL PROTECTION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ERYTHROCYTE; ERYTHROCYTE GHOST; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0012369987     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(98)00198-1     Document Type: Article

References (29)

1. Van Dyke B.R., Saltman P. Hemoglobin A mechanism for the generation of hydroxyl radicals . Free Radic. Biol. Med. 20:1996;985-989.
2. Lynch R.E., Fridovich I. Permeation of the erythrocyte stroma by superoxide radical. J. Biol. Chem. 253:1978;4697-4699.
3. Diaz M.N., Frei B., Vita J.A., Keaney J.F. Jr. Mechanisms of disease - Antioxidants and atherosclerotic heart disease. N. Engl. J. Med. 337:1997;408-416.
4. Niki E. Antioxidants in relation to lipid peroxidation. Chem. Phys. Lipids. 44:1987;227-253.
5. Buettner G.R. The pecking order of free radicals and antioxidants lipid peroxidation, α-tocopherol, and ascorbate . Arch. Biochem. Biophys. 300:1993;535-543.
6. Kamal-Eldin A., Appelqvist L.A. The chemistry and antioxidant properties of tocopherols and tocotrienols. Lipids. 31:1996;671-701.
7. Bowry V.W., Mohr D., Cleary J., Stocker R. Prevention of tocopherol-mediated peroxidation in ubiquinol-10-free human low density lipoprotein. J. Biol. Chem. 270:1995;5756-5763.
8. Santanam N., Parthasarathy S. Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases. J. Clin. Invest. 95:1995;2594-2600.
9. Niki E., Kawakami A., Yamamoto Y., Kamiya Y. Oxidation of lipids. VIII. Synergistic inhibition of oxidation of phosphatidylcholine liposome in aqueous dispersion by vitamin E and vitamin C. Bull. Chem. Soc. Jpn. 58:1985;1971-1975.
10. Scarpa M., Rigo A., Maiorino M., Ursini F., Gregolin C. Formation of α-tocopherol radical and recycling of α-tocopherol by ascorbate during peroxidation of phosphatidylcholine liposomes. An electron paramagnetic resonance study. Biochim. Biophys. Acta. 801:1984;215-219.
11. Constantinescu A., Han D., Packer L. Vitamin E recycling in human erythrocyte membranes. J. Biol. Chem. 268:1993;10906-10913.
12. May J.M., Qu Z.-C., Mendiratta S. Protection and recycling of α-tocopherol in human erythrocytes by intracellular ascorbic acid. Arch. Biochem. Biophys. 349:1998;281-289.
13. Zhang Y., Fung L.W.M. The roles of ascorbic acid and other antioxidants in the erythrocyte in reducing membrane nitroxide radicals. Free Radic. Biol. Med. 16:1994;215-222.
14. May J.M., Qu Z.C., Cobb C.E. Accessibility and reactivity of ascorbate 6-palmitate bound to erythrocyte membranes. Free Radic. Biol. Med. 21:1996;471-480.
15. Washko P.W., Wang Y., Levine M. Ascorbic acid recycling in human neutrophils. J. Biol. Chem. 268:1993;15531-15535.
16. Avron M., Shavit N. A sensitive and simple method for determination of ferrocyanide. Anal. Biochem. 6:1963;549-554.
17. Thorstensen K., Aisen P. Release of iron from diferric transferrin in the presence of rat liver plasma membranes no evidence of a plasma membrane diferric transferrin reductase . Biochim. Biophys. Acta. 1052:1990;29-35.
18. Lang J.K., Gohil K., Packer L. Simultaneous determination of tocopherols, ubiquinols, and ubiquinones in blood, plasma, tissue homogenates, and subcellular fractions. Anal. Biochem. 157:1986;106-116.
19. May J.M., Qu Z.C., Morrow J.D. Interaction of ascorbate and α-tocopherol in resealed human erythrocyte ghosts - Transmembrane electron transfer and protection from lipid peroxidation. J. Biol. Chem. 271:1996;10577-10582.
20. Steck T.L., Kant J.A. Preparation of impermeable ghosts and inside-out vesicles from human erythrocyte membranes. Methods Enzymol. 31:1974;172-180.
21. Yu J., Fischman D.A., Steck T.L. Selective solubilization of protein and phospholipids from red blood cell membranes by nonionic detergents. J. Supramol. Struct. 1:1973;233-238.
22. May J.M., Qu Z.C., Whitesell R.R., Cobb C.E. Ascorbate recycling in human erythrocytes Role of GSH in reducing dehydroascorbate . Free Radic. Biol. Med. 20:1996;543-551.
23. Schweinzer E., Goldenberg H. Monodehydroascorbate reductase activity in the surface membrane of leukemic cells. Characterization by a ferricyanide-driven redox cycle. Eur. J. Biochem. 218:1993;1057-1062.
24. Grebing C., Crane F.L., Löw H., Hall K. A transmembranous NADH-dehydrogenase in human erythrocyte membranes. J. Bioenerg. Biomembr. 16:1984;517-533.
25. Crane F.L., Löw H., Clark M.G. Plasma membrane redox enzymes. Martonosi A.N. The enzymes of biological membranes. 2nd Ed. 1985;465-510 Plenum Press, New York.
26. May J.M., Qu Z.-C., Whitesell R.R. Ascorbate is the major electron donor for a transmembrane oxidoreductase of human erythrocytes. Biochim. Biophys. Acta. 1238:1995;127-136.
27. De Ritter E., Cohen N., Rubin S.H. Physiological availability of dehydro-L-ascorbic acid and palmitoyl-L-ascorbic acid. Science. 113:1951;628-631.
28. Bergsten P., Amitai G., Kehrl J., Dhariwal K.R., Klein H.G., Levine M. Millimolar concentrations of ascorbic acid in purified human mononuclear leukocytes. Depletion and reaccumulation. J. Biol. Chem. 265:1990;2584-2587.
29. Phillips C.L., Combs S.B., Pinnell S.R. Effects of ascorbic acid on proliferation and collagen synthesis in relation to the donor age of human dermal fibroblasts. J. Invest. Dermatol. 103:1994;228-232.