Vitamin C crosses the blood-brain barrier in the oxidized form through the glucose transporters

Journal of Clinical Investigation

Volumn 100, Issue 11, 1997, Pages 2842-2848

  Agus, David B ^a   Gambhir, Sanjiv Sam ^b   Pardridge, William M ^c   Spielholz, Charles ^a   Baselga, José ^d   Vera, Juan Carlos ^a   Golde, David W ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Antioxidants; Ascorbic acid; Dehydroascorbic acid; GLUT1; Neurodegenerative disease

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; DEHYDROASCORBIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; ENDOTHELIUM CELL; GASTROINTESTINAL ABSORPTION; GLUCOSE TRANSPORT; HEMATOPOIESIS; HYDROLYSIS; LEUKOCYTE FUNCTION; MOUSE; NERVE DEGENERATION; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; VITAMIN METABOLISM;

EID: 0031469362     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119832     Document Type: Article

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