Polarized osteoclasts put marks of tartrate-resistant acid phosphatase on dentin slices - A simple method for identifying polarized osteoclasts

Bone

Volumn 49, Issue 6, 2011, Pages 1331-1339

  Nakayama, Takahiro ^a   Mizoguchi, Toshihide ^a   Uehara, Shunsuke ^a   Yamashita, Teruhito ^a   Kawahara, Ichiro ^a   Kobayashi, Yasuhiro ^a   Moriyama, Yoshinori ^b   Kurihara, Saburo ^a   Sahara, Noriyuki ^a   Ozawa, Hidehiro ^c   Udagawa, Nobuyuki ^a   Takahashi, Naoyuki ^a  

^a MATSUMOTO DENTAL UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c NIIGATA UNIVERSITY   (Japan)

Author keywords

Actin rings; Cathepsin K; Osteoclasts; TRAP marks; V ATPase

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACTIN; ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CATHEPSIN K; HEMATOXYLIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CELL VIABILITY; CONTROLLED STUDY; DENTIN; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OSTEOCLAST; POLARIZATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION;

ACID PHOSPHATASE; ACTINS; ALENDRONATE; ANIMALS; BONE RESORPTION; CALCITONIN; CATHEPSIN K; CELL POLARITY; CYTOLOGICAL TECHNIQUES; DENTIN; ISOENZYMES; MALE; MICE; OSTEOCLASTS; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 81355127348     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.09.045     Document Type: Article

References (56)

1. Boyle W.J., Simonet W.S., Lacey D.L. Osteoclast differentiation and activation. Nature 2003, 423:337-342.
2. Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 1999, 20:345-357.
3. Hall T.J., Chambers T.J. Molecular aspects of osteoclast function. Inflamm Res 1996, 45:1-9.
4. Vaananen H.K., Zhao H., Mulari M., Halleen J.M. The cell biology of osteoclast function. J Cell Sci 2000, 113(Pt 3):377-381.
5. Nakamura I., Duong le T., Rodan S.B., Rodan G.A. Involvement of αv β3 integrins in osteoclast function. J Bone Miner Metab 2007, 25:337-344.
6. Zou W., Teitelbaum S.L. Integrins, growth factors, and the osteoclast cytoskeleton. Ann N Y Acad Sci 2010, 1192:27-31.
7. Jurdic P., Saltel F., Chabadel A., Destaing O. Podosome and sealing zone: specificity of the osteoclast model. Eur J Cell Biol 2006, 85:195-202.
8. Vaananen H.K., Horton M. The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure. J Cell Sci 1995, 108(Pt 8):2729-2732.
9. Takahashi N., Ejiri S., Yanagisawa S., Ozawa H. Regulation of osteoclast polarization. Odontology 2007, 95:1-9.
10. Nesbitt S.A., Horton M.A. Trafficking of matrix collagens through bone-resorbing osteoclasts. Science 1997, 276:266-269.
11. Salo J., Lehenkari P., Mulari M., Metsikko K., Vaananen H.K. Removal of osteoclast bone resorption products by transcytosis. Science 1997, 276:270-273.
12. Mulari M.T., Zhao H., Lakkakorpi P.T., Vaananen H.K. Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake. Traffic 2003, 4:113-125.
13. Vaananen H.K., Laitala-Leinonen T. Osteoclast lineage and function. Arch Biochem Biophys 2008, 473:132-138.
14. Bune A.J., Hayman A.R., Evans M.J., Cox T.M. Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disordered macrophage inflammatory responses and reduced clearance of the pathogen, Staphylococcus aureus. Immunology 2001, 102:103-113.
15. Halleen J.M., Tiitinen S.L., Ylipahkala H., Fagerlund K.M., Vaananen H.K. Tartrate-resistant acid phosphatase 5b (TRACP 5b) as a marker of bone resorption. Clin Lab 2006, 52:499-509.
16. Gay C.V., Mueller W.J. Carbonic anhydrase and osteoclasts: localization by labeled inhibitor autoradiography. Science 1974, 183:432-434.
17. Margolis D.S., Szivek J.A., Lai L.W., Lien Y.H. Phenotypic characteristics of bone in carbonic anhydrase II-deficient mice. Calcif Tissue Int 2008, 82:66-76.
18. Reponen P., Sahlberg C., Munaut C., Thesleff I., Tryggvason K. High expression of 92-kDa type IV collagenase (gelatinase) in the osteoclast lineage during mouse development. Ann N Y Acad Sci 1994, 732:472-475.
19. Tezuka K., Nemoto K., Tezuka Y., Sato T., Ikeda Y., Kobori M., et al. Identification of matrix metalloproteinase 9 in rabbit osteoclasts. J Biol Chem 1994, 269:15006-15009.
20. Saftig P., Hunziker E., Wehmeyer O., Jones S., Boyde A., Rommerskirch W., et al. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice. Proc Natl Acad Sci U S A 1998, 95:13453-13458.
21. Tezuka K., Tezuka Y., Maejima A., Sato T., Nemoto K., Kamioka H., et al. Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts. J Biol Chem 1994, 269:1106-1109.
22. Blair H.C., Teitelbaum S.L., Ghiselli R., Gluck S. Osteoclastic bone resorption by a polarized vacuolar proton pump. Science 1989, 245:855-857.
23. +-ATPase type in the ruffled borders of osteoclasts. J Cell Biol 1990, 111:1305-1311.
24. Minkin C. Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function. Calcif Tissue Int 1982, 34:285-290.
25. Sahara N. Cellular events at the onset of physiological root resorption in rabbit deciduous teeth. Anat Rec 2001, 264:387-396.
26. Takahashi N., Udagawa N., Kobayashi Y., Suda T. Generation of osteoclasts in vitro, and assay of osteoclast activity. Methods Mol Med 2007, 135:285-301.
27. Hayman A.R., Jones S.J., Boyde A., Foster D., Colledge W.H., Carlton M.B., et al. Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis. Development 1996, 122:3151-3162.
28. Angel N.Z., Walsh N., Forwood M.R., Ostrowski M.C., Cassady A.I., Hume D.A. Transgenic mice overexpressing tartrate-resistant acid phosphatase exhibit an increased rate of bone turnover. J Bone Miner Res 2000, 15:103-110.
29. Briggs T.A., Rice G.I., Daly S., Urquhart J., Gornall H., Bader-Meunier B., et al. Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature. Nat Genet 2011, 43:127-131.
30. Lausch E., Janecke A., Bros M., Trojandt S., Alanay Y., De Laet C., et al. Genetic deficiency of tartrate-resistant acid phosphatase associated with skeletal dysplasia, cerebral calcifications and autoimmunity. Nat Genet 2011, 43:132-137.
31. Alatalo S.L., Ivaska K.K., Waguespack S.G., Econs M.J., Vaananen H.K., Halleen J.M. Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis). Clin Chem 2004, 50:883-890.
32. Kirstein B., Chambers T.J., Fuller K. Secretion of tartrate-resistant acid phosphatase by osteoclasts correlates with resorptive behavior. J Cell Biochem 2006, 98:1085-1094.
33. Fuller K., Ross J.L., Szewczyk K.A., Moss R., Chambers T.J. Bone is not essential for osteoclast activation. PLoS One 2010, 5.
34. Findlay D.M., Martin T.J. Receptors of calciotropic hormones. Horm Metab Res 1997, 29:128-134.
35. Suzuki H., Nakamura I., Takahashi N., Ikuhara T., Matsuzaki K., Isogai Y., et al. Calcitonin-induced changes in the cytoskeleton are mediated by a signal pathway associated with protein kinase A in osteoclasts. Endocrinology 1996, 137:4685-4690.
36. Rodan G.A., Fleisch H.A. Bisphosphonates: mechanisms of action. J Clin Invest 1996, 97:2692-2696.
37. Russell R.G., Watts N.B., Ebetino F.H., Rogers M.J. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int 2008, 19:733-759.
38. +-ATPase in incorporation of risedronate into osteoclasts. Bone 2003, 32:341-349.
39. Burgess T.L., Qian Y., Kaufman S., Ring B.D., Van G., Capparelli C., et al. The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 1999, 145:527-538.
40. Jimi E., Akiyama S., Tsurukai T., Okahashi N., Kobayashi K., Udagawa N., et al. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J Immunol 1999, 163:434-442.
41. Roelofs A.J., Coxon F.P., Ebetino F.H., Lundy M.W., Henneman Z.J., Nancollas G.H., et al. Fluorescent risedronate analogues reveal bisphosphonate uptake by bone marrow monocytes and localization around osteocytes in vivo. J Bone Miner Res 2010, 25:606-616.
42. Sato M., Grasser W., Endo N., Akins R., Simmons H., Thompson D.D., et al. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J Clin Invest 1991, 88:2095-2105.
43. Murakami H., Takahashi N., Tanaka S., Nakamura I., Udagawa N., Nakajo S., et al. Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts. Bone 1997, 20:399-404.
44. Tamura T., Takahashi N., Akatsu T., Sasaki T., Udagawa N., Tanaka S., et al. New resorption assay with mouse osteoclast-like multinucleated cells formed in vitro. J Bone Miner Res 1993, 8:953-960.
45. 3 in osteoclast differentiation and function. Methods Enzymol 1997, 282:223-235.
46. Akatsu T., Tamura T., Takahashi N., Udagawa N., Tanaka S., Sasaki T., et al. Preparation and characterization of a mouse osteoclast-like multinucleated cell population. J Bone Miner Res 1992, 7:1297-1306.
47. Okumura S., Mizoguchi T., Sato N., Yamaki M., Kobayashi Y., Yamauchi H., et al. Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks. Bone 2006, 39:684-693.
48. Reinholt F.P., Widholm S.M., Ek-Rylander B., Andersson G. Ultrastructural localization of a tartrate-resistant acid ATPase in bone. J Bone Miner Res 1990, 5:1055-1061.
49. McNiven M.A. Dynamin: a molecular motor with pinchase action. Cell 1998, 94:151-154.
50. Pucadyil T.J., Schmid S.L. Conserved functions of membrane active GTPases in coated vesicle formation. Science 2009, 325:1217-1220.
51. Ochoa G.C., Slepnev V.I., Neff L., Ringstad N., Takei K., Daniell L., et al. A functional link between dynamin and the actin cytoskeleton at podosomes. J Cell Biol 2000, 150:377-389.
52. 402 phosphorylation and SRC binding in osteoclasts. Mol Cell Biol 2009, 29:3644-3656.
53. Kaija H., Alatalo S.L., Halleen J.M., Lindqvist Y., Schneider G., Vaananen H.K., et al. Phosphatase and oxygen radical-generating activities of mammalian purple acid phosphatase are functionally independent. Biochem Biophys Res Commun 2002, 292:128-132.
54. Janckila A.J., Woodford T.A., Lam K.W., Li C.Y., Yam L.T. Protein-tyrosine phosphatase activity of hairy cell tartrate-resistant acid phosphatase. Leukemia 1992, 6:199-203.
55. Ek-Rylander B., Flores M., Wendel M., Heinegard D., Andersson G. Dephosphorylation of osteopontin and bone sialoprotein by osteoclastic tartrate-resistant acid phosphatase. Modulation of osteoclast adhesion in vitro. J Biol Chem 1994, 269:14853-14856.
56. Vaaraniemi J., Halleen J.M., Kaarlonen K., Ylipahkala H., Alatalo S.L., Andersson G., et al. Intracellular machinery for matrix degradation in bone-resorbing osteoclasts. J Bone Miner Res 2004, 19:1432-1440.