-
1
-
-
0031456158
-
Wnt signaling: A common theme in animal development
-
Cadigan KM, Nusse R. Wnt signaling: a common theme in animal development. Genes Dev. 1997; 11: 3286-3305.
-
(1997)
Genes Dev.
, vol.11
, pp. 3286-3305
-
-
Cadigan, K.M.1
Nusse, R.2
-
2
-
-
33745065756
-
Common critical pathways in embryogenesis and cancer
-
Kelleher FC, Fennelly D, Rafferty M. Common critical pathways in embryogenesis and cancer. Acta Oncol. 2006; 45: 375-388.
-
(2006)
Acta Oncol.
, vol.45
, pp. 375-388
-
-
Kelleher, F.C.1
Fennelly, D.2
Rafferty, M.3
-
3
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A. 1999; 96: 5522-5527.
-
(1999)
Proc Natl Acad Sci U S A.
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
-
4
-
-
0038498213
-
Survivin and molecular pathogenesis of colorectal cancer
-
Kim PJ, Plescia J, Clevers H, et al. Survivin and molecular pathogenesis of colorectal cancer. Lancet. 2003; 362: 205-209.
-
(2003)
Lancet.
, vol.362
, pp. 205-209
-
-
Kim, P.J.1
Plescia, J.2
Clevers, H.3
-
5
-
-
68549106083
-
E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer
-
Schmalhofer O, Brabletz S, Brabletz T. E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev. 2009; 28: 151-166.
-
(2009)
Cancer Metastasis Rev.
, vol.28
, pp. 151-166
-
-
Schmalhofer, O.1
Brabletz, S.2
Brabletz, T.3
-
6
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol. 2007; 19: 150-158.
-
(2007)
Curr Opin Cell Biol.
, vol.19
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
7
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
Barker N, Clevers H. Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov. 2006; 5: 997-1014.
-
(2006)
Nat Rev Drug Discov.
, vol.5
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
9
-
-
77950822827
-
Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer
-
Valle J, Wasan H, Palmer DH, et al. Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer. N Engl J Med. 2010; 362: 1273-1281.
-
(2010)
N Engl J Med.
, vol.362
, pp. 1273-1281
-
-
Valle, J.1
Wasan, H.2
Palmer, D.H.3
-
10
-
-
78650465341
-
Advances in photodynamic therapy for the treatment of hilar biliary tract cancer
-
Kiesslich T, Neureiter D, Wolkersdorfer GW, et al. Advances in photodynamic therapy for the treatment of hilar biliary tract cancer. Future Oncol. 2010; 6: 1925-1936.
-
(2010)
Future Oncol.
, vol.6
, pp. 1925-1936
-
-
Kiesslich, T.1
Neureiter, D.2
Wolkersdorfer, G.W.3
-
11
-
-
63449126671
-
Targeted medical therapy of biliary tract cancer: Recent advances and future perspectives
-
Hopfner M, Schuppan D, Scherubl H. Targeted medical therapy of biliary tract cancer: recent advances and future perspectives. World J Gastroenterol. 2008; 14: 7021-7032.
-
(2008)
World J Gastroenterol.
, vol.14
, pp. 7021-7032
-
-
Hopfner, M.1
Schuppan, D.2
Scherubl, H.3
-
12
-
-
0037778008
-
The Wnt signaling pathway and its role in tumor development
-
Lustig B, Behrens J. The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol. 2003; 129: 199-221.
-
(2003)
J Cancer Res Clin Oncol.
, vol.129
, pp. 199-221
-
-
Lustig, B.1
Behrens, J.2
-
13
-
-
33747339465
-
Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
-
Gordon MD, Nusse R. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem. 2006; 281: 22429-22433.
-
(2006)
J Biol Chem.
, vol.281
, pp. 22429-22433
-
-
Gordon, M.D.1
Nusse, R.2
-
14
-
-
74549225756
-
Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition
-
Kiesslich T, Alinger B, Wolkersdorfer GW, et al. Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. Int J Oncol. 2010; 36: 49-58.
-
(2010)
Int J Oncol.
, vol.36
, pp. 49-58
-
-
Kiesslich, T.1
Alinger, B.2
Wolkersdorfer, G.W.3
-
15
-
-
0031948695
-
Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: An immunohistochemical study
-
Ashida K, Terada T, Kitamura Y, et al. Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study. Hepatology. 1998; 27: 974-982.
-
(1998)
Hepatology.
, vol.27
, pp. 974-982
-
-
Ashida, K.1
Terada, T.2
Kitamura, Y.3
-
16
-
-
0034835564
-
Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma
-
Sugimachi K, Taguchi K, Aishima S, et al. Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma. Mod Pathol. 2001; 14: 900-905.
-
(2001)
Mod Pathol.
, vol.14
, pp. 900-905
-
-
Sugimachi, K.1
Taguchi, K.2
Aishima, S.3
-
17
-
-
33644831221
-
Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas
-
Tokumoto N, Ikeda S, Ishizaki Y, et al. Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas. Int J Oncol. 2005; 27: 973-980.
-
(2005)
Int J Oncol.
, vol.27
, pp. 973-980
-
-
Tokumoto, N.1
Ikeda, S.2
Ishizaki, Y.3
-
18
-
-
3843114402
-
2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: A novel powerful and selective inhibitor of protein kinase CK2
-
Pagano MA, Meggio F, Ruzzene M, et al. 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2. Biochem Biophys Res Commun. 2004; 321: 1040-1044.
-
(2004)
Biochem Biophys Res Commun.
, vol.321
, pp. 1040-1044
-
-
Pagano, M.A.1
Meggio, F.2
Ruzzene, M.3
-
19
-
-
41649098360
-
A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities
-
Handeli S, Simon JA. A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities. Mol Cancer Ther. 2008; 7: 521-529.
-
(2008)
Mol Cancer Ther.
, vol.7
, pp. 521-529
-
-
Handeli, S.1
Simon, J.A.2
-
20
-
-
33745865489
-
Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling
-
Gao Y, Wang HY. Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling. J Biol Chem. 2006; 281: 18394-18400.
-
(2006)
J Biol Chem.
, vol.281
, pp. 18394-18400
-
-
Gao, Y.1
Wang, H.Y.2
-
21
-
-
22344440218
-
CK2 as a positive regulator of Wnt signalling and tumourigenesis
-
Seldin DC, Landesman-Bollag E, Farago M, et al. CK2 as a positive regulator of Wnt signalling and tumourigenesis. Mol Cell Biochem. 2005; 274: 63-67.
-
(2005)
Mol Cell Biochem.
, vol.274
, pp. 63-67
-
-
Seldin, D.C.1
Landesman-Bollag, E.2
Farago, M.3
-
22
-
-
12844274417
-
Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells
-
Park CH, Chang JY, Hahm ER, et al. Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells. Biochem Biophys Res Commun. 2005; 328: 227-234.
-
(2005)
Biochem Biophys Res Commun.
, vol.328
, pp. 227-234
-
-
Park, C.H.1
Chang, J.Y.2
Hahm, E.R.3
-
23
-
-
58149382600
-
Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma
-
Gelebart P, Anand M, Armanious H, et al. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood. 2008; 112: 5171-5179.
-
(2008)
Blood.
, vol.112
, pp. 5171-5179
-
-
Gelebart, P.1
Anand, M.2
Armanious, H.3
-
24
-
-
67649946192
-
Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway
-
Shan BE, Wang MX, Li RQ. Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway. Cancer Invest. 2009; 27: 604-612.
-
(2009)
Cancer Invest.
, vol.27
, pp. 604-612
-
-
Shan, B.E.1
Wang, M.X.2
Li, R.Q.3
-
25
-
-
77951945986
-
Uptake and phototoxicity of meso-tetrahydroxyphenyl chlorine are highly variable in human biliary tract cancer cell lines and correlate with markers of differentiation and proliferation
-
Kiesslich T, Neureiter D, Alinger B, et al. Uptake and phototoxicity of meso-tetrahydroxyphenyl chlorine are highly variable in human biliary tract cancer cell lines and correlate with markers of differentiation and proliferation. Photochem Photobiol Sci. 2010; 9: 734-743.
-
(2010)
Photochem Photobiol Sci.
, vol.9
, pp. 734-743
-
-
Kiesslich, T.1
Neureiter, D.2
Alinger, B.3
-
26
-
-
79960128382
-
Assessment of cell proliferation with resazurin-based fluorescent dye
-
Czekanska EM. Assessment of cell proliferation with resazurin-based fluorescent dye. Methods Mol Biol. 2011; 740: 27-32.
-
(2011)
Methods Mol Biol.
, vol.740
, pp. 27-32
-
-
Czekanska, E.M.1
-
27
-
-
80052271274
-
Nef from SIV(mac239) decreases proliferation and migration of adenoid-cystic carcinoma cells and inhibits angiogenesis
-
Cai C, Rodepeter FR, Rossmann A, et al. Nef from SIV(mac239) decreases proliferation and migration of adenoid-cystic carcinoma cells and inhibits angiogenesis. Oral Oncol. 2011; 47: 847-854.
-
(2011)
Oral Oncol.
, vol.47
, pp. 847-854
-
-
Cai, C.1
Rodepeter, F.R.2
Rossmann, A.3
-
28
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman DM, Karhadkar SS, Maitra A, et al. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature. 2003; 425: 846-851.
-
(2003)
Nature.
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
-
29
-
-
41549115361
-
Wnt/beta-catenin signaling: New (and old) players and new insights
-
Huang H, He X. Wnt/beta-catenin signaling: new (and old) players and new insights. Curr Opin Cell Biol. 2008; 20: 119-125.
-
(2008)
Curr Opin Cell Biol.
, vol.20
, pp. 119-125
-
-
Huang, H.1
He, X.2
-
30
-
-
33646790670
-
-
[Internet]
-
[Internet] Nusse R. The Wnt Homepage http://www.stanford.edu/group/nusselab/cgi-bin/wnt/
-
The Wnt Homepage
-
-
Nusse, R.1
-
31
-
-
5444265502
-
The Wnt connection to tumorigenesis
-
Behrens J, Lustig B. The Wnt connection to tumorigenesis. Int J Dev Biol. 2004; 48: 477-487.
-
(2004)
Int J Dev Biol.
, vol.48
, pp. 477-487
-
-
Behrens, J.1
Lustig, B.2
-
32
-
-
56549112554
-
A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors
-
Miranda-Carboni GA, Krum SA, Yee K, et al. A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev. 2008; 22: 3121-3134.
-
(2008)
Genes Dev.
, vol.22
, pp. 3121-3134
-
-
Miranda-Carboni, G.A.1
Krum, S.A.2
Yee, K.3
-
33
-
-
34548668897
-
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT
-
Yde CW, Frogne T, Lykkesfeldt AE, et al. Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT. Cancer Lett. 2007; 256: 229-237.
-
(2007)
Cancer Lett.
, vol.256
, pp. 229-237
-
-
Yde, C.W.1
Frogne, T.2
Lykkesfeldt, A.E.3
-
34
-
-
70449519966
-
Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation
-
Chiu WT, Shen SC, Chow JM, et al. Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. Neurobiol Dis. 2010; 37: 118-129.
-
(2010)
Neurobiol Dis.
, vol.37
, pp. 118-129
-
-
Chiu, W.T.1
Shen, S.C.2
Chow, J.M.3
-
35
-
-
79952033433
-
Quercetin inhibits a large panel of kinases implicated in cancer cell biology
-
Boly R, Gras T, Lamkami T, et al. Quercetin inhibits a large panel of kinases implicated in cancer cell biology. Int J Oncol. 2011; 38: 833-842.
-
(2011)
Int J Oncol.
, vol.38
, pp. 833-842
-
-
Boly, R.1
Gras, T.2
Lamkami, T.3
-
36
-
-
38349116517
-
Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
-
Duncan JS, Litchfield DW. Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta. 2008; 1784: 33-47.
-
(2008)
Biochim Biophys Acta.
, vol.1784
, pp. 33-47
-
-
Duncan, J.S.1
Litchfield, D.W.2
-
37
-
-
66149132324
-
Myricetin suppresses invasion and migration of human lung adenocarcinoma A549 cells: Possible mediation by blocking the ERK signaling pathway
-
Shih YW, Wu PF, Lee YC, et al. Myricetin suppresses invasion and migration of human lung adenocarcinoma A549 cells: possible mediation by blocking the ERK signaling pathway. J Agric Food Chem. 2009; 57: 3490-3499.
-
(2009)
J Agric Food Chem.
, vol.57
, pp. 3490-3499
-
-
Shih, Y.W.1
Wu, P.F.2
Lee, Y.C.3
-
38
-
-
69849092498
-
Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2
-
Siegelin MD, Gaiser T, Habel A, et al. Myricetin sensitizes malignant glioma cells to TRAIL-mediated apoptosis by down-regulation of the short isoform of FLIP and bcl-2. Cancer Lett. 2009; 283: 230-238.
-
(2009)
Cancer Lett.
, vol.283
, pp. 230-238
-
-
Siegelin, M.D.1
Gaiser, T.2
Habel, A.3
-
39
-
-
70450286260
-
Akt is a direct target for myricetin to inhibit cell transformation
-
Kumamoto T, Fujii M, Hou DX. Akt is a direct target for myricetin to inhibit cell transformation. Mol Cell Biochem. 2009; 332: 33-41.
-
(2009)
Mol Cell Biochem.
, vol.332
, pp. 33-41
-
-
Kumamoto, T.1
Fujii, M.2
Hou, D.X.3
-
40
-
-
74649084195
-
The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cells
-
Lopez-Lazaro M, Willmore E, Austin CA. The dietary flavonoids myricetin and fisetin act as dual inhibitors of DNA topoisomerases I and II in cells. Mutat Res. 2010; 696: 41-47.
-
(2010)
Mutat Res.
, vol.696
, pp. 41-47
-
-
Lopez-Lazaro, M.1
Willmore, E.2
Austin, C.A.3
-
41
-
-
58549107213
-
Myricetin directly targets JAK1 to inhibit cell transformation
-
Kumamoto T, Fujii M, Hou DX. Myricetin directly targets JAK1 to inhibit cell transformation. Cancer Lett. 2009; 275: 17-26.
-
(2009)
Cancer Lett.
, vol.275
, pp. 17-26
-
-
Kumamoto, T.1
Fujii, M.2
Hou, D.X.3
-
42
-
-
79960885211
-
Silymarin targets beta-catenin signaling in blocking migration/invasion of human melanoma cells
-
Vaid M, Prasad R, Sun Q, et al. Silymarin targets beta-catenin signaling in blocking migration/invasion of human melanoma cells. PLoS One. 2011; 6:e23000.
-
(2011)
PLoS One.
, vol.6
-
-
Vaid, M.1
Prasad, R.2
Sun, Q.3
-
43
-
-
33750053855
-
Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription
-
Tapia JC, Torres VA, Rodriguez DA, et al. Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. Proc Natl Acad Sci U S A. 2006; 103: 15079-15084.
-
(2006)
Proc Natl Acad Sci U S A.
, vol.103
, pp. 15079-15084
-
-
Tapia, J.C.1
Torres, V.A.2
Rodriguez, D.A.3
-
44
-
-
0036524672
-
Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT
-
Plaetzer K, Kiesslich T, Krammer B, et al. Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT. Photochem Photobiol Sci. 2002; 1: 172-177.
-
(2002)
Photochem Photobiol Sci.
, vol.1
, pp. 172-177
-
-
Plaetzer, K.1
Kiesslich, T.2
Krammer, B.3
-
45
-
-
34848916118
-
Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1
-
Lee KW, Kang NJ, Rogozin EA, et al. Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1. Carcinogenesis. 2007; 28: 1918-1927.
-
(2007)
Carcinogenesis.
, vol.28
, pp. 1918-1927
-
-
Lee, K.W.1
Kang, N.J.2
Rogozin, E.A.3
-
46
-
-
70449585521
-
Efficacy and mechanism of anti-tumor action of new potential CK2 inhibitors toward glioblastoma cells
-
Kaminska B, Ellert-Miklaszewska A, Oberbek A, et al. Efficacy and mechanism of anti-tumor action of new potential CK2 inhibitors toward glioblastoma cells. Int J Oncol. 2009; 35: 1091-1100.
-
(2009)
Int J Oncol.
, vol.35
, pp. 1091-1100
-
-
Kaminska, B.1
Ellert-Miklaszewska, A.2
Oberbek, A.3
-
47
-
-
77953229921
-
Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro
-
Lawnicka H, Kowalewicz-Kulbat M, Sicinska P, et al. Anti-neoplastic effect of protein kinase CK2 inhibitor, 2-dimethylamino-4,5,6,7-tetrabromobenzimidazole (DMAT), on growth and hormonal activity of human adrenocortical carcinoma cell line (H295R) in vitro. Cell Tissue Res. 2010; 340: 371-379.
-
(2010)
Cell Tissue Res.
, vol.340
, pp. 371-379
-
-
Lawnicka, H.1
Kowalewicz-Kulbat, M.2
Sicinska, P.3
-
48
-
-
79960013995
-
Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT
-
Sass G, Klinger N, Sirma H, et al. Inhibition of experimental HCC growth in mice by use of the kinase inhibitor DMAT. Int J Oncol. 2011; 39: 433-442.
-
(2011)
Int J Oncol.
, vol.39
, pp. 433-442
-
-
Sass, G.1
Klinger, N.2
Sirma, H.3
-
49
-
-
78650321320
-
CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy
-
Siddiqui-Jain A, Drygin D, Streiner N, et al. CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy. Cancer Res. 2010; 70: 10288-10298.
-
(2010)
Cancer Res.
, vol.70
, pp. 10288-10298
-
-
Siddiqui-Jain, A.1
Drygin, D.2
Streiner, N.3
-
50
-
-
81255130623
-
Current Status of Therapeutic Targeting of Developmental Signalling Pathways in Oncology
-
epub
-
Kiesslich T, Berr F, Alinger B, et al. Current Status of Therapeutic Targeting of Developmental Signalling Pathways in Oncology. Curr Pharm Biotechnol. 2011; epub.
-
(2011)
Curr Pharm Biotechnol.
-
-
Kiesslich, T.1
Berr, F.2
Alinger, B.3
|