Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation

Oncogene

Volumn 30, Issue 46, 2011, Pages 4645-4655

  Sriram, G ^a   Reichman, C ^a   Tunceroglu, A ^a   Kaushal, N ^a   Saleh, T ^b   MacHida, K ^c   Mayer, B ^c   Ge, Q ^d   Li, J ^d   Hornbeck, P ^d   Kalodimos, C G ^b   Birge, R B ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^d CELL SIGNALING TECHNOLOGY   (United States)

Author keywords

Abl transactivation; Crk tyrosine phosphorylation; SH2 domains

Indexed keywords

ABELSON KINASE; BIOTIN; CRK LIKE PROTEIN; EPIDERMAL GROWTH FACTOR; PHOSPHOPEPTIDE; PROTEIN SH3; PROTEIN Y251; STREPTAVIDIN; TYROSINE; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHRONIC MYELOID LEUKEMIA; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION;

CELL LINE, TUMOR; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MUTATION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-ABL; PROTO-ONCOGENE PROTEINS C-CRK; SRC HOMOLOGY DOMAINS; TRANSCRIPTIONAL ACTIVATION; TYROSINE;

EID: 81255171678     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.170     Document Type: Article

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