Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways

Neurochemistry International

Volumn 59, Issue 8, 2011, Pages 1109-1122

  Szegedi, Viktor ^a   Juhász, Gábor ^b   Zhang, Xiaoqun ^c   Barkóczi, Balázs ^a   Qi, Hongshi ^c   Madeira, Alexandra ^c   Kapus, Gábor ^d   Svenningsson, Per ^c   Spedding, Michael ^e   Penke, Botond ^a,b  

^a BAY ZOLTÁN NONPROFIT LTD FOR APPLIED RESEARCH   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c KAROLINSKA INSTITUTE   (Sweden)

^d EGIS PHARMACEUTICALS LTD   (Hungary)

^e INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Antidepressant; Glutamate receptors; NMDA; Phosphorylation; Signaling pathway; Synaptic plasticity

Indexed keywords

AMPA RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TIANEPTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; IN VIVO STUDY; MALE; MOUSE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROPHYSIOLOGICAL PHENOMENA; GLUTAMIC ACID; HIPPOCAMPUS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LONG-TERM POTENTIATION; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RECEPTORS, AMPA; RECEPTORS, GLUTAMATE; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; THIAZEPINES;

MURINAE;

EID: 81255166086     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.10.008     Document Type: Article

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