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Current Osteoporosis Reports
Volumn 9, Issue 4, 2011, Pages 196-201
Events in articular chondrocytes with aging
Author keywords

Aging; Chondrocytes; Osteoarthritis; Senescence
Indexed keywords

OSTEOGENIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;
EID: 81255161464     PISSN: 15441873     EISSN: 15442241     Source Type: Journal    
DOI: 10.1007/s11914-011-0070-3     Document Type: Article
Times cited : (34)
References (71)
  • 1
    • 77957953600 scopus 로고    scopus 로고
    • Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation-United States, 2007-2009
    • HJ Cheng JM Hootman LB Murphy GA Langmaid CG Helmick 2010 Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation-United States, 2007-2009 MMWR Morb Mortal Wkly Rep 59 1261 5
    • (2010) MMWR Morb Mortal Wkly Rep , vol.59 , pp. 1261-5
    • Cheng, H.J.1    Hootman, J.M.2    Murphy, L.B.3    Langmaid, G.A.4    Helmick, C.G.5
  • 2
    • 0036398455 scopus 로고    scopus 로고
    • Aging, articular cartilage chondrocyte senescence and osteoarthritis
    • DOI 10.1023/A:1020185404126
    • JA Martin JA Buckwalter 2002 Aging, articular cartilage chondrocyte senescence and osteoarthritis Biogerontology 3 257 64 12237562 10.1023/A:1020185404126 1:CAS:528:DC%2BD38XmvVKhs7c%3D (Pubitemid 35174238)
    • (2002) Biogerontology , vol.3 , Issue.5 , pp. 257-264
    • Martin, J.A.1    Buckwalter, J.A.2
  • 3
    • 0038753871 scopus 로고    scopus 로고
    • The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair
    • JA Martin JA Buckwalter 2003 The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair J Bone Joint Surg Am 85-A Suppl 2 106 10 12721352 (Pubitemid 36535052)
    • (2003) Journal of Bone and Joint Surgery - Series A , vol.85 , Issue.SUPPL. 1 , pp. 106-110
    • Martin, J.A.1    Buckwalter, J.A.2
  • 4
    • 0028222637 scopus 로고
    • Age-related changes in cartilage proteoglycans: Quantitative electron microscopic studies
    • DOI 10.1002/jemt.1070280506
    • JA Buckwalter PJ Roughley LC Rosenberg 1994 Age-related changes in cartilage proteoglycans: quantitative electron microscopic studies Microsc Res Tech 28 398 408 7919527 10.1002/jemt.1070280506 1:CAS:528:DyaK2MXhtVWku7Y%3D (Pubitemid 24222671)
    • (1994) Microscopy Research and Technique , vol.28 , Issue.5 , pp. 398-408
    • Buckwalter, J.A.1    Roughley, P.J.2    Rosenberg, L.C.3
  • 5
    • 0032907148 scopus 로고    scopus 로고
    • Age-related changes in the synthesis of link protein and aggrecan in human articular cartilage: Implications for aggregate stability
    • DOI 10.1042/0264-6021:3370077
    • MC Bolton J Dudhia MT Bayliss 1999 Age-related changes in the synthesis of link protein and aggrecan in human articular cartilage: implications for aggregate stability Biochem J 337 Pt 1 77 82 9854027 10.1042/0264-6021:3370077 1:CAS:528:DyaK1MXjslaksg%3D%3D (Pubitemid 29039085)
    • (1999) Biochemical Journal , vol.337 , Issue.1 , pp. 77-82
    • Bolton, M.C.1    Dudhia, J.2    Bayliss, M.T.3
  • 7
    • 0033680154 scopus 로고    scopus 로고
    • Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: Studies in a non-human primate model of naturally occurring disease
    • 11014363 10.1002/1529-0131(200009)43:9<2110::AID-ANR23>3.0.CO;2-U 1:CAS:528:DC%2BD3cXnt1KnsLY%3D
    • RF Loeser G Shanker CS Carlson, et al. 2000 Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease Arthritis Rheum 43 2110 20 11014363 10.1002/1529-0131(200009)43:9<2110::AID-ANR23>3.0.CO;2-U 1:CAS:528:DC%2BD3cXnt1KnsLY%3D
    • (2000) Arthritis Rheum , vol.43 , pp. 2110-20
    • Loeser, R.F.1    Shanker, G.2    Carlson, C.S.3
  • 8
    • 0031193785 scopus 로고    scopus 로고
    • Age-related decline in chondrocyte response to insulin-like growth factor-I: The role of growth factor binding proteins
    • DOI 10.1002/jor.1100150403
    • JA Martin SM Ellerbroek JA Buckwalter 1997 Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins J Orthop Res 15 491 8 9379257 10.1002/jor.1100150403 1:CAS:528:DyaK2sXntVClu70%3D (Pubitemid 27433361)
    • (1997) Journal of Orthopaedic Research , vol.15 , Issue.4 , pp. 491-498
    • Martin, J.A.1    Ellerbroek, S.M.2    Buckwalter, J.A.3
  • 10
    • 33144481368 scopus 로고    scopus 로고
    • Reduced transforming growth factor-beta signaling in cartilage of old mice: Role in impaired repair capacity
    • 16277687 10.1186/ar1833 1:STN:280:DC%2BD2MrpvVChug%3D%3D
    • EN Blaney Davidson A Scharstuhl EL Vitters, et al. 2005 Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity Arthritis Res Ther 7 R1338 47 16277687 10.1186/ar1833 1:STN:280:DC%2BD2MrpvVChug%3D%3D
    • (2005) Arthritis Res Ther , vol.7 , pp. 1338-47
    • Blaney Davidson, E.N.1    Scharstuhl, A.2    Vitters, E.L.3
  • 11
    • 0036893256 scopus 로고    scopus 로고
    • Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice
    • DOI 10.1136/ard.61.12.1095
    • A Scharstuhl HM van Beuningen EL Vitters, et al. 2002 Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice Ann Rheum Dis 61 1095 8 12429542 10.1136/ard.61.12.1095 1:CAS:528:DC%2BD38Xps1KltLk%3D (Pubitemid 35397358)
    • (2002) Annals of the Rheumatic Diseases , vol.61 , Issue.12 , pp. 1095-1098
    • Scharstuhl, A.1    Van Beuningen, H.M.2    Vitters, E.L.3    Van Der Kraan, P.M.4    Van Den Berg, W.B.5
  • 12
    • 0028169834 scopus 로고
    • Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint
    • 8078307
    • HM van Beuningen PM van der Kraan OJ Arntz, et al. 1994 Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint Lab Invest 71 279 90 8078307
    • (1994) Lab Invest , vol.71 , pp. 279-90
    • Van Beuningen, H.M.1    Van Der Kraan, P.M.2    Arntz, O.J.3
  • 13
    • 77955497148 scopus 로고    scopus 로고
    • A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis
    • 20156325 10.1186/ar3173
    • PM van der Kraan EN Blaney Davidson WB van den Berg 2010 A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis Arthritis Res Ther 12 201 20156325 10.1186/ar3173
    • (2010) Arthritis Res Ther , vol.12 , pp. 201
    • Van Der Kraan, P.M.1    Blaney Davidson, E.N.2    Van Den Berg, W.B.3
  • 15
    • 77953061313 scopus 로고    scopus 로고
    • Advanced glycation end products in foods and a practical guide to their reduction in the diet
    • 20497781 10.1016/j.jada.2010.03.018 This is a database of how various food preparation methods affect levels of AGE formation in food e12
    • J Uribarri S Woodruff S Goodman, et al. 2010 Advanced glycation end products in foods and a practical guide to their reduction in the diet J Am Diet Assoc 110 911 16 e12 20497781 10.1016/j.jada.2010.03.018 This is a database of how various food preparation methods affect levels of AGE formation in food
    • (2010) J Am Diet Assoc , vol.110 , pp. 911-16
    • Uribarri, J.1    Woodruff, S.2    Goodman, S.3
  • 16
    • 0035787070 scopus 로고    scopus 로고
    • Protein glycation, diabetes, and aging
    • DOI 10.1210/rp.56.1.1
    • P Ulrich A Cerami 2001 Protein glycation, diabetes, and aging Recent Prog Horm Res 56 1 21 11237208 10.1210/rp.56.1.1 1:CAS:528:DC%2BD3MXitV2lurg%3D (Pubitemid 36068052)
    • (2001) Recent Progress in Hormone Research , vol.56 , pp. 1-21
    • Ulrich, P.1    Cerami, A.2
  • 17
    • 43049162900 scopus 로고    scopus 로고
    • Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes
    • 10.1093/rheumatology/kem376 1:CAS:528:DC%2BD1cXmslKht7o%3D This is a study determining the proinflammatory mechanisms of AGEs on chondrocytes
    • SS Nah IY Choi CK Lee, et al. 2008 Effects of advanced glycation end products on the expression of COX-2, PGE2 and NO in human osteoarthritic chondrocytes Rheumatology (Oxford) 47 425 31 10.1093/rheumatology/kem376 1:CAS:528:DC%2BD1cXmslKht7o%3D This is a study determining the proinflammatory mechanisms of AGEs on chondrocytes
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 425-31
    • Nah, S.S.1    Choi, I.Y.2    Lee, C.K.3
  • 18
    • 34247373125 scopus 로고    scopus 로고
    • Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-α in human osteoarthritic chondrocytes
    • DOI 10.1016/j.febslet.2007.03.090, PII S0014579307003687
    • SS Nah IY Choi B Yoo, et al. 2007 Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-alpha in human osteoarthritic chondrocytes FEBS Lett 581 1928 32 17434489 10.1016/j.febslet. 2007.03.090 1:CAS:528:DC%2BD2sXksV2rtLs%3D (Pubitemid 46628804)
    • (2007) FEBS Letters , vol.581 , Issue.9 , pp. 1928-1932
    • Nah, S.-S.1    Choi, I.-Y.2    Yoo, B.3    Kim, Y.G.4    Moon, H.-B.5    Lee, C.-K.6
  • 19
    • 84862833509 scopus 로고    scopus 로고
    • Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes
    • Huang CY, Lai KY, Hung LF et al. Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes. Rheumatology (Oxford) 2011.
    • (2011) Rheumatology (Oxford)
    • Huang, C.Y.1    Lai, K.Y.2    Hung, L.F.3
  • 21
    • 0036901116 scopus 로고    scopus 로고
    • Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage
    • DOI 10.1002/art.10627
    • AC Chen MM Temple DM Ng, et al. 2002 Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage Arthritis Rheum 46 3212 7 12483725 10.1002/art.10627 1:CAS:528: DC%2BD3sXjslGitg%3D%3D (Pubitemid 35453530)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.12 , pp. 3212-3217
    • Chen, A.C.1    Temple, M.M.2    Ng, D.M.3    Verzijl, N.4    DeGroot, J.5    TeKoppele, J.M.6    Sah, R.L.7
  • 22
    • 0032519990 scopus 로고    scopus 로고
    • Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage
    • 9461529 1:CAS:528:DyaK1cXhs12jsrY%3D
    • RA Bank MT Bayliss FP Lafeber, et al. 1998 Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage Biochem J 330 Pt 1 345 51 9461529 1:CAS:528: DyaK1cXhs12jsrY%3D
    • (1998) Biochem J , vol.330 , Issue.PART 1 , pp. 345-51
    • Bank, R.A.1    Bayliss, M.T.2    Lafeber, F.P.3
  • 23
    • 77249116145 scopus 로고    scopus 로고
    • Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells
    • 20133001 10.1016/j.jhep.2009.12.007 1:CAS:528:DC%2BC3cXisFejtrs%3D
    • EL Guimaraes C Empsen A Geerts, et al. 2010 Advanced glycation end products induce production of reactive oxygen species via the activation of NADPH oxidase in murine hepatic stellate cells J Hepatol 52 389 97 20133001 10.1016/j.jhep.2009.12.007 1:CAS:528:DC%2BC3cXisFejtrs%3D
    • (2010) J Hepatol , vol.52 , pp. 389-97
    • Guimaraes, E.L.1    Empsen, C.2    Geerts, A.3
  • 24
    • 77958026890 scopus 로고    scopus 로고
    • Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells
    • 20969783 10.1186/1475-2840-9-66
    • K Yang XQ Wang YS He, et al. 2010 Advanced glycation end products induce chemokine/cytokine production via activation of p38 pathway and inhibit proliferation and migration of bone marrow mesenchymal stem cells Cardiovasc Diabetol 9 66 20969783 10.1186/1475-2840-9-66
    • (2010) Cardiovasc Diabetol , vol.9 , pp. 66
    • Yang, K.1    Wang, X.Q.2    He, Y.S.3
  • 26
    • 79951518607 scopus 로고    scopus 로고
    • Molecular targets of oxidative stress
    • 21309749 10.1042/BJ20101695 1:CAS:528:DC%2BC3MXhvVCnsL4%3D
    • SV Avery 2011 Molecular targets of oxidative stress Biochem J 434 201 10 21309749 10.1042/BJ20101695 1:CAS:528:DC%2BC3MXhvVCnsL4%3D
    • (2011) Biochem J , vol.434 , pp. 201-10
    • Avery, S.V.1
  • 27
    • 71049194727 scopus 로고    scopus 로고
    • Nitrative and oxidative stress in toxicology and disease
    • 19656995 10.1093/toxsci/kfp179 1:CAS:528:DC%2BD1MXhtlGitL3K
    • RA Roberts DL Laskin CV Smith, et al. 2009 Nitrative and oxidative stress in toxicology and disease Toxicol Sci 112 4 16 19656995 10.1093/toxsci/kfp179 1:CAS:528:DC%2BD1MXhtlGitL3K
    • (2009) Toxicol Sci , vol.112 , pp. 4-16
    • Roberts, R.A.1    Laskin, D.L.2    Smith, C.V.3
  • 29
    • 0030612396 scopus 로고    scopus 로고
    • Detection of superoxide and NAPDH oxidase in porcine articular chondrocytes
    • DOI 10.1016/S0891-5849(97)00054-3, PII S0891584997000543
    • TS Hiran PJ Moulton JT Hancock 1997 Detection of superoxide and NADPH oxidase in porcine articular chondrocytes Free Radic Biol Med 23 736 43 9296450 10.1016/S0891-5849(97)00054-3 1:CAS:528:DyaK2sXls1ylur8%3D (Pubitemid 27364867)
    • (1997) Free Radical Biology and Medicine , vol.23 , Issue.5 , pp. 736-743
    • Hiran, T.S.1    Moulton, P.J.2    Hancock, J.T.3
  • 30
    • 0034733622 scopus 로고    scopus 로고
    • Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation: Possible role in cartilage aging and the pathogenesis of osteoarthritis
    • DOI 10.1074/jbc.M907604199
    • ML Tiku R Shah GT Allison 2000 Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation. Possible role in cartilage aging and the pathogenesis of osteoarthritis J Biol Chem 275 20069 76 10867027 10.1074/jbc.M907604199 1:CAS:528:DC%2BD3cXkslahu7Y%3D (Pubitemid 30441616)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.26 , pp. 20069-20076
    • Tiku, M.L.1    Shah, R.2    Allison, G.T.3
  • 31
    • 20944433514 scopus 로고    scopus 로고
    • Vulnerability to ROS-induced cell death in ageing articular cartilage: The role of antioxidant enzyme activity
    • DOI 10.1016/j.joca.2005.02.011, PII S1063458405000592
    • N Jallali H Ridha C Thrasivoulou, et al. 2005 Vulnerability to ROS-induced cell death in ageing articular cartilage: the role of antioxidant enzyme activity Osteoarthritis Cartilage 13 614 22 15979014 10.1016/j.joca.2005. 02.011 1:STN:280:DC%2BD2MzjtVahtQ%3D%3D (Pubitemid 40867861)
    • (2005) Osteoarthritis and Cartilage , vol.13 , Issue.7 , pp. 614-622
    • Jallali, N.1    Ridha, H.2    Thrasivoulou, C.3    Underwood, C.4    Butler, P.E.M.5    Cowen, T.6
  • 32
    • 79952451523 scopus 로고    scopus 로고
    • The role of mitochondria in osteoarthritis
    • 21200395 10.1038/nrrheum.2010.213 1:CAS:528:DC%2BC3MXislOktbw%3D This is a review on the role mitochondrial dysfunction plays in the pathogenesis of OA
    • FJ Blanco I Rego C Ruiz-Romero 2011 The role of mitochondria in osteoarthritis Nat Rev Rheumatol 7 161 9 21200395 10.1038/nrrheum.2010.213 1:CAS:528:DC%2BC3MXislOktbw%3D This is a review on the role mitochondrial dysfunction plays in the pathogenesis of OA
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 161-9
    • Blanco, F.J.1    Rego, I.2    Ruiz-Romero, C.3
  • 33
    • 42149126726 scopus 로고    scopus 로고
    • Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis
    • DOI 10.1016/j.joca.2007.09.012, PII S1063458407002993
    • CM Davies F Guilak JB Weinberg, et al. 2008 Reactive nitrogen and oxygen species in interleukin-1-mediated DNA damage associated with osteoarthritis Osteoarthritis Cartilage 16 624 30 17945515 10.1016/j.joca.2007.09.012 1:STN:280:DC%2BD1c3mvF2ksw%3D%3D (Pubitemid 351524696)
    • (2008) Osteoarthritis and Cartilage , vol.16 , Issue.5 , pp. 624-630
    • Davies, C.M.1    Guilak, F.2    Weinberg, J.B.3    Fermor, B.4
  • 34
    • 26444473434 scopus 로고    scopus 로고
    • Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: Oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function
    • 15743486 10.1186/ar1499 1:CAS:528:DC%2BD2MXhsleltbw%3D
    • K Yudoh T Nguyen H Nakamura, et al. 2005 Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function Arthritis Res Ther 7 R380 91 15743486 10.1186/ar1499 1:CAS:528:DC%2BD2MXhsleltbw%3D
    • (2005) Arthritis Res Ther , vol.7 , pp. 380-91
    • Yudoh, K.1    Nguyen, T.2    Nakamura, H.3
  • 35
    • 73849152727 scopus 로고    scopus 로고
    • N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis
    • 19725096 1:CAS:528:DC%2BC3cXhsFCmsbk%3D
    • S Nakagawa Y Arai O Mazda, et al. 2010 N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis J Orthop Res 28 156 63 19725096 1:CAS:528:DC%2BC3cXhsFCmsbk%3D
    • (2010) J Orthop Res , vol.28 , pp. 156-63
    • Nakagawa, S.1    Arai, Y.2    Mazda, O.3
  • 36
    • 4043161974 scopus 로고    scopus 로고
    • Mitochondrial redox control of matrix metalloproteinases
    • DOI 10.1016/j.freeradbiomed.2004.06.008, PII S0891584904004617
    • KK Nelson JA Melendez 2004 Mitochondrial redox control of matrix metalloproteinases Free Radic Biol Med 37 768 84 15304253 10.1016/j. freeradbiomed.2004.06.008 1:CAS:528:DC%2BD2cXmsVGgsLc%3D (Pubitemid 39078549)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.6 , pp. 768-784
    • Nelson, K.K.1    Melendez, J.A.2
  • 37
    • 79952296675 scopus 로고    scopus 로고
    • Extrinsic mechanisms involved in age-related defective bone formation
    • 21209032 10.1210/jc.2010-2113 1:CAS:528:DC%2BC3MXjvFahsLo%3D
    • PJ Marie M Kassem 2011 Extrinsic mechanisms involved in age-related defective bone formation J Clin Endocrinol Metab 96 600 9 21209032 10.1210/jc.2010-2113 1:CAS:528:DC%2BC3MXjvFahsLo%3D
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. 600-9
    • Marie, P.J.1    Kassem, M.2
  • 38
    • 70350621347 scopus 로고    scopus 로고
    • Computational biomechanics of articular cartilage of human knee joint: Effect of osteochondral defects
    • 19660759 10.1016/j.jbiomech.2009.07.022 1:STN:280:DC%2BD1Mjislyktw%3D%3D
    • R Shirazi A Shirazi-Adl 2009 Computational biomechanics of articular cartilage of human knee joint: effect of osteochondral defects J Biomech 42 2458 65 19660759 10.1016/j.jbiomech.2009.07.022 1:STN:280:DC%2BD1Mjislyktw%3D%3D
    • (2009) J Biomech , vol.42 , pp. 2458-65
    • Shirazi, R.1    Shirazi-Adl, A.2
  • 40
    • 78349291080 scopus 로고    scopus 로고
    • Mechanical loading, cartilage degradation, and arthritis
    • 21062294 10.1111/j.1749-6632.2010.05808.x 1:CAS:528: DC%2BC3MXltlCjtA%3D%3D
    • HB Sun 2010 Mechanical loading, cartilage degradation, and arthritis Ann N Y Acad Sci 1211 37 50 21062294 10.1111/j.1749-6632.2010.05808.x 1:CAS:528:DC%2BC3MXltlCjtA%3D%3D
    • (2010) Ann N y Acad Sci , vol.1211 , pp. 37-50
    • Sun, H.B.1
  • 41
    • 0034689774 scopus 로고    scopus 로고
    • P21(Waf1/Cip1/Sdi1)-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells
    • BD Chang EV Broude J Fang, et al. 2000 p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells Oncogene 19 2165 70 10815808 10.1038/sj.onc.1203573 1:CAS:528:DC%2BD3cXjsVymurg%3D (Pubitemid 30251382)
    • (2000) Oncogene , vol.19 , Issue.17 , pp. 2165-2170
    • Chang, B.-D.1    Broude, E.V.2    Fang, J.3    Kalinichenko, T.V.4    Abdryashitov, R.5    Poole, J.C.6    Roninson, I.B.7
  • 42
    • 79955143892 scopus 로고    scopus 로고
    • Senescence of chondrocytes in aging articular cartilage: GADD45beta mediates p21 expression in association with C/EBPbeta in senescence-accelerated mice
    • 21353395 10.1016/j.prp.2011.01.007 1:CAS:528:DC%2BC3MXltFyjt7s%3D This is an in vivo model of aging used to elucidate mechanisms of chondrocyte senescence
    • H Shimada H Sakakima K Tsuchimochi, et al. 2011 Senescence of chondrocytes in aging articular cartilage: GADD45beta mediates p21 expression in association with C/EBPbeta in senescence-accelerated mice Pathol Res Pract 207 225 31 21353395 10.1016/j.prp.2011.01.007 1:CAS:528:DC%2BC3MXltFyjt7s%3D This is an in vivo model of aging used to elucidate mechanisms of chondrocyte senescence
    • (2011) Pathol Res Pract , vol.207 , pp. 225-31
    • Shimada, H.1    Sakakima, H.2    Tsuchimochi, K.3
  • 43
    • 58149145316 scopus 로고    scopus 로고
    • Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells
    • 18780287 10.1002/jcp.21582 1:CAS:528:DC%2BD1cXhsFahsbnF
    • B Hoffman DA Liebermann 2009 Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells J Cell Physiol 218 26 31 18780287 10.1002/jcp.21582 1:CAS:528:DC%2BD1cXhsFahsbnF
    • (2009) J Cell Physiol , vol.218 , pp. 26-31
    • Hoffman, B.1    Liebermann, D.A.2
  • 45
    • 58849150874 scopus 로고    scopus 로고
    • The telosome/shelterin complex and its functions
    • 18828880 10.1186/gb-2008-9-9-232
    • H Xin D Liu Z Songyang 2008 The telosome/shelterin complex and its functions Genome Biol 9 232 18828880 10.1186/gb-2008-9-9-232
    • (2008) Genome Biol , vol.9 , pp. 232
    • Xin, H.1    Liu, D.2    Songyang, Z.3
  • 46
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • 18680434 10.1146/annurev.genet.41.110306.130350 1:CAS:528: DC%2BD1cXhsFemtbrI
    • W Palm T de Lange 2008 How shelterin protects mammalian telomeres Annu Rev Genet 42 301 34 18680434 10.1146/annurev.genet.41.110306.130350 1:CAS:528:DC%2BD1cXhsFemtbrI
    • (2008) Annu Rev Genet , vol.42 , pp. 301-34
    • Palm, W.1    De Lange, T.2
  • 47
    • 3242881692 scopus 로고    scopus 로고
    • The XRCC genes: Expanding roles in DNA double-strand break repair
    • DOI 10.1016/j.dnarep.2004.04.012, PII S1568786404001430
    • J Thacker MZ Zdzienicka 2004 The XRCC genes: expanding roles in DNA double-strand break repair DNA Repair (Amst) 3 1081 90 10.1016/j.dnarep.2004.04. 012 1:CAS:528:DC%2BD2cXmtVeqtL4%3D (Pubitemid 38997951)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 1081-1090
    • Thacker, J.1    Zdzienicka, M.Z.2
  • 48
    • 0032750220 scopus 로고    scopus 로고
    • Diverse and dynamic functions of the Sir silencing complex
    • DOI 10.1038/15458
    • L Guarente 1999 Diverse and dynamic functions of the Sir silencing complex Nat Genet 23 281 5 10545947 10.1038/15458 1:CAS:528:DyaK1MXnt1Gnsrk%3D (Pubitemid 29526424)
    • (1999) Nature Genetics , vol.23 , Issue.3 , pp. 281-285
    • Guarente, L.1
  • 49
    • 79955893457 scopus 로고    scopus 로고
    • Oxidative stress induces senescence in chondrocytes
    • 21284033 10.1002/jor.21348 1:CAS:528:DC%2BC3MXlvFWjuro%3D This paper shows molecular mechanisms mediating the effects of oxidative stress on chondrocyte senescence
    • A Brandl A Hartmann V Bechmann, et al. 2011 Oxidative stress induces senescence in chondrocytes J Orthop Res 29 1114 20 21284033 10.1002/jor.21348 1:CAS:528:DC%2BC3MXlvFWjuro%3D This paper shows molecular mechanisms mediating the effects of oxidative stress on chondrocyte senescence
    • (2011) J Orthop Res , vol.29 , pp. 1114-20
    • Brandl, A.1    Hartmann, A.2    Bechmann, V.3
  • 50
    • 0034617210 scopus 로고    scopus 로고
    • Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells
    • DOI 10.1074/jbc.M908162199
    • WY Park JS Park KA Cho, et al. 2000 Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells J Biol Chem 275 20847 52 10781609 10.1074/jbc.M908162199 1:CAS:528:DC%2BD3cXkvVyhtLw%3D (Pubitemid 30457678)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.27 , pp. 20847-20852
    • Park, W.-Y.1    Park, J.-S.2    Cho, K.-A.3    Kim, D.-I.4    Ko, Y.-G.5    Seo, J.-S.6    Park, S.C.7
  • 51
    • 33644899652 scopus 로고    scopus 로고
    • Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: Possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis
    • 16508959 10.1002/art.21639 1:CAS:528:DC%2BD28XjtV2lsL8%3D
    • SM Dai ZZ Shan H Nakamura, et al. 2006 Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis Arthritis Rheum 54 818 31 16508959 10.1002/art.21639 1:CAS:528:DC%2BD28XjtV2lsL8%3D
    • (2006) Arthritis Rheum , vol.54 , pp. 818-31
    • Dai, S.M.1    Shan, Z.Z.2    Nakamura, H.3
  • 52
    • 67749086596 scopus 로고    scopus 로고
    • Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: Potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing
    • 20374325 10.1111/j.1756-185X.2009.01390.x
    • K Yudoh Y Shi R Karasawa 2009 Angiogenic growth factors inhibit chondrocyte ageing in osteoarthritis: potential involvement of catabolic stress-induced overexpression of caveolin-1 in cellular ageing Int J Rheum Dis 12 90 9 20374325 10.1111/j.1756-185X.2009.01390.x
    • (2009) Int J Rheum Dis , vol.12 , pp. 90-9
    • Yudoh, K.1    Shi, Y.2    Karasawa, R.3
  • 53
    • 0034966785 scopus 로고    scopus 로고
    • Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritic human articular knee cartilage: A study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage
    • DOI 10.1002/1529-0131(200106)44:6<1304::AID-ART222>3.0.CO;2-T
    • T Aigner M Hemmel D Neureiter, et al. 2001 Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage Arthritis Rheum 44 1304 12 11407689 10.1002/1529-0131(200106)44:6<1304::AID- ART222>3.0.CO;2-T 1:STN:280:DC%2BD3MzksVOgtA%3D%3D (Pubitemid 32537528)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.6 , pp. 1304-1312
    • Aigner, T.1    Hemmel, M.2    Neureiter, D.3    Gebhard, P.M.4    Zeiler, G.5    Kirchner, T.6    McKenna, L.7
  • 54
    • 13144261687 scopus 로고    scopus 로고
    • Chondrocyte apoptosis in development, aging and disease
    • DOI 10.1016/S0945-053X(98)90024-5
    • WE Horton Jr L Feng C Adams 1998 Chondrocyte apoptosis in development, aging and disease Matrix Biol 17 107 15 9694591 10.1016/S0945-053X(98)90024-5 1:CAS:528:DyaK1cXkt1Ontbc%3D (Pubitemid 28310245)
    • (1998) Matrix Biology , vol.17 , Issue.2 , pp. 107-115
    • Horton Jr., W.E.1    Feng, L.2    Adams, C.3
  • 55
    • 0041571728 scopus 로고    scopus 로고
    • The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes
    • DOI 10.1002/art.11209
    • RF Loeser CA Pacione S Chubinskaya 2003 The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytes Arthritis Rheum 48 2188 96 12905472 10.1002/art.11209 1:CAS:528: DC%2BD3sXntVWgsb0%3D (Pubitemid 36959199)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.8 , pp. 2188-2196
    • Loeser, R.F.1    Pacione, C.A.2    Chubinskaya, S.3
  • 56
    • 0028909420 scopus 로고
    • Protein kinases. 4. Protein kinase CK2: An enzyme with multiple substrates and a puzzling regulation
    • 7896000 1:CAS:528:DyaK2MXks12ntrw%3D
    • JE Allende CC Allende 1995 Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation FASEB J 9 313 23 7896000 1:CAS:528:DyaK2MXks12ntrw%3D
    • (1995) FASEB J , vol.9 , pp. 313-23
    • Allende, J.E.1    Allende, C.C.2
  • 57
    • 79955740493 scopus 로고    scopus 로고
    • Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-alpha-mediated chondrocyte death through apoptosis and autophagy
    • 21559479 10.1371/journal.pone.0019163 1:CAS:528:DC%2BC3MXlslGgt7k%3D
    • SW Lee YS Song SY Lee, et al. 2011 Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-alpha-mediated chondrocyte death through apoptosis and autophagy PLoS One 6 e19163 21559479 10.1371/journal.pone. 0019163 1:CAS:528:DC%2BC3MXlslGgt7k%3D
    • (2011) PLoS One , vol.6 , pp. 19163
    • Lee, S.W.1    Song, Y.S.2    Lee, S.Y.3
  • 58
    • 59049100910 scopus 로고    scopus 로고
    • Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis
    • 19139395 10.1073/pnas.0806062106 1:CAS:528:DC%2BD1MXhsFyisr8%3D
    • N Taniguchi B Carames L Ronfani, et al. 2009 Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis Proc Natl Acad Sci U S A 106 1181 6 19139395 10.1073/pnas.0806062106 1:CAS:528:DC%2BD1MXhsFyisr8%3D
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1181-6
    • Taniguchi, N.1    Carames, B.2    Ronfani, L.3
  • 59
    • 78349235475 scopus 로고    scopus 로고
    • Tendon-derived stem/progenitor cell aging: Defective self-renewal and altered fate
    • 20569237 10.1111/j.1474-9726.2010.00598.x 1:CAS:528:DC%2BC3cXht1Oju7bJ
    • Z Zhou T Akinbiyi L Xu, et al. 2010 Tendon-derived stem/progenitor cell aging: defective self-renewal and altered fate Aging Cell 9 911 5 20569237 10.1111/j.1474-9726.2010.00598.x 1:CAS:528:DC%2BC3cXht1Oju7bJ
    • (2010) Aging Cell , vol.9 , pp. 911-5
    • Zhou, Z.1    Akinbiyi, T.2    Xu, L.3
  • 60
    • 79251578611 scopus 로고    scopus 로고
    • Physiological loading of joints prevents cartilage degradation through CITED2
    • 20826544 10.1096/fj.10-164277 1:CAS:528:DC%2BC3MXls1Gmtg%3D%3D
    • DJ Leong YH Li XI Gu, et al. 2011 Physiological loading of joints prevents cartilage degradation through CITED2 FASEB J 25 182 91 20826544 10.1096/fj.10-164277 1:CAS:528:DC%2BC3MXls1Gmtg%3D%3D
    • (2011) FASEB J , vol.25 , pp. 182-91
    • Leong, D.J.1    Li, Y.H.2    Gu, X.I.3
  • 61
    • 0344012451 scopus 로고    scopus 로고
    • CITED2-mediated Regulation of MMP-1 and MMP-13 in Human Chondrocytes under Flow Shear
    • DOI 10.1074/jbc.M304652200
    • H Yokota MB Goldring HB Sun 2003 CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear J Biol Chem 278 47275 80 12960175 10.1074/jbc.M304652200 1:CAS:528:DC%2BD3sXovFKkur8%3D (Pubitemid 37452316)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.47 , pp. 47275-47280
    • Yokota, H.1    Goldring, M.B.2    Sun, H.B.3
  • 62
    • 0033775218 scopus 로고    scopus 로고
    • Osteoarthritis: New insights. Part 1: The disease and its risk factors
    • 11033593 1:STN:280:DC%2BD3M%2Fht1SitA%3D%3D
    • DT Felson RC Lawrence PA Dieppe, et al. 2000 Osteoarthritis: new insights. Part 1: the disease and its risk factors Ann Intern Med 133 635 46 11033593 1:STN:280:DC%2BD3M%2Fht1SitA%3D%3D
    • (2000) Ann Intern Med , vol.133 , pp. 635-46
    • Felson, D.T.1    Lawrence, R.C.2    Dieppe, P.A.3
  • 64
    • 0041735145 scopus 로고    scopus 로고
    • Osteoarthritis: Understanding the pathophysiology, genetics, and treatments
    • V Sinkov T Cymet 2003 Osteoarthritis: understanding the pathophysiology, genetics, and treatments J Natl Med Assoc 95 475 82 12856913 (Pubitemid 37101948)
    • (2003) Journal of the National Medical Association , vol.95 , Issue.6 , pp. 475-482
    • Sinkov, V.1    Cymet, T.2
  • 65
    • 0034749242 scopus 로고    scopus 로고
    • Clinical assessment of the osteoarthritis patient
    • DOI 10.1053/berh.2001.0171
    • G Peat P Croft E Hay 2001 Clinical assessment of the osteoarthritis patient Best Pract Res Clin Rheumatol 15 527 44 11567537 10.1053/berh.2001.0171 1:STN:280:DC%2BD3MritFOhsw%3D%3D (Pubitemid 33026118)
    • (2001) Best Practice and Research in Clinical Rheumatology , vol.15 , Issue.4 , pp. 527-544
    • Peat, G.1    Croft, P.2    Hay, E.3
  • 66
    • 0035076295 scopus 로고    scopus 로고
    • Articular cartilage and changes in arthritis An introduction: Cell biology of osteoarthritis
    • DOI 10.1186/ar148
    • LJ Sandell T Aigner 2001 Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis Arthritis Res 3 107 13 11178118 10.1186/ar148 1:CAS:528:DC%2BD3MXhsValtLw%3D (Pubitemid 32237037)
    • (2001) Arthritis Research , vol.3 , Issue.2 , pp. 107-113
    • Sandell, L.J.1    Aigner, T.2
  • 67
    • 38149051545 scopus 로고    scopus 로고
    • Regional differences in chondrocyte metabolism in osteoarthritis: A detailed analysis by laser capture microdissection
    • 18163492 10.1002/art.23175 1:CAS:528:DC%2BD1cXhslOjtrc%3D
    • N Fukui Y Ikeda T Ohnuki, et al. 2008 Regional differences in chondrocyte metabolism in osteoarthritis: a detailed analysis by laser capture microdissection Arthritis Rheum 58 154 63 18163492 10.1002/art.23175 1:CAS:528:DC%2BD1cXhslOjtrc%3D
    • (2008) Arthritis Rheum , vol.58 , pp. 154-63
    • Fukui, N.1    Ikeda, Y.2    Ohnuki, T.3
  • 68
    • 0027451811 scopus 로고
    • Immunohistochemical analysis of 3-B-3(-) and 7-D-4 epitope expression in canine osteoarthritis
    • DOI 10.1002/art.1780361211
    • DM Visco B Johnstone MA Hill, et al. 1993 Immunohistochemical analysis of 3-B-(-) and 7-D-4 epitope expression in canine osteoarthritis Arthritis Rheum 36 1718 25 7504489 10.1002/art.1780361211 1:CAS:528:DyaK2cXivFGru7c%3D (Pubitemid 23360012)
    • (1993) Arthritis and Rheumatism , vol.36 , Issue.12 , pp. 1718-1725
    • Visco, D.M.1    Johnstone, B.2    Hill, M.A.3    Jolly, G.A.4    Caterson, B.5
  • 69
    • 77955491633 scopus 로고    scopus 로고
    • Age-related changes in the musculoskeletal system and the development of osteoarthritis
    • 20699160 10.1016/j.cger.2010.03.002 This is a review on the effect of aging joint tissues on the development of OA
    • RF Loeser 2010 Age-related changes in the musculoskeletal system and the development of osteoarthritis Clin Geriatr Med 26 371 86 20699160 10.1016/j.cger.2010.03.002 This is a review on the effect of aging joint tissues on the development of OA
    • (2010) Clin Geriatr Med , vol.26 , pp. 371-86
    • Loeser, R.F.1
  • 70
    • 84880570618 scopus 로고    scopus 로고
    • Oxidative stress in older adults: Effects of physical fitness
    • Traustadottir T, Davies SS, Su Y, et al. Oxidative stress in older adults: effects of physical fitness. Age (Dordr) 2011.
    • (2011) Age (Dordr)
    • Traustadottir, T.1    Davies, S.S.2    Su, Y.3
  • 71
    • 70449704575 scopus 로고    scopus 로고
    • Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats
    • 19608208 10.1016/j.metabol.2009.05.025 1:CAS:528:DC%2BD1MXht1OnsrnM
    • P Boor P Celec M Behuliak, et al. 2009 Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats Metabolism 58 1669 77 19608208 10.1016/j.metabol.2009.05.025 1:CAS:528:DC%2BD1MXht1OnsrnM
    • (2009) Metabolism , vol.58 , pp. 1669-77
    • Boor, P.1    Celec, P.2    Behuliak, M.3

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