-
1
-
-
0028145753
-
Organization of the human genome
-
Craig, I.W. Organization of the human genome. J. Inherit. Metab. Dis. 17, 391-402 (1994)
-
(1994)
J. Inherit. Metab. Dis.
, vol.17
, pp. 391-402
-
-
Craig, I.W.1
-
2
-
-
0032076941
-
Centromeres take flight: α satellite and the quest for the human centromere
-
Murphy, T.D. & Karpen, G.H. Centromeres take flight: α satellite and the quest for the human centromere. Cell 93, 317-320 (1998).
-
(1998)
Cell
, vol.93
, pp. 317-320
-
-
Murphy, T.D.1
Karpen, G.H.2
-
3
-
-
0032076461
-
Beyond the nucleosome: Epigenetic aspects of position-effect variegation in Drosophila
-
Wakimoto, B.T. Beyond the nucleosome: epigenetic aspects of position-effect variegation in Drosophila. Cell 93, 321-324 (1998).
-
(1998)
Cell
, vol.93
, pp. 321-324
-
-
Wakimoto, B.T.1
-
4
-
-
0032076121
-
Yeast heterochromatin: Regulation of its assembly and inheritance by histones
-
Grunstein, M. Yeast heterochromatin: regulation of its assembly and inheritance by histones. Cell 93, 325-328 (1998).
-
(1998)
Cell
, vol.93
, pp. 325-328
-
-
Grunstein, M.1
-
5
-
-
0023340731
-
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae
-
Rine, J. & Herskowitz, I. Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116, 9-22 (1987).
-
(1987)
Genetics
, vol.116
, pp. 9-22
-
-
Rine, J.1
Herskowitz, I.2
-
6
-
-
0030951007
-
Silent information regulator protein complexes in S. cerevisiae: A Sir2/Sir4 complex and evidence for a regulatory domain in Sir4 that inhibits its interaction with Sir3
-
Moazed, D., Kistler, A., Axelrod. A., Rine, J. & Johnson, A.D. Silent information regulator protein complexes in S. cerevisiae: a Sir2/Sir4 complex and evidence for a regulatory domain in Sir4 that inhibits its interaction with Sir3. Proc. Natl Acad. Sci. USA 94, 2186-2191 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 2186-2191
-
-
Moazed, D.1
Kistler, A.2
Axelrod, A.3
Rine, J.4
Johnson, A.D.5
-
7
-
-
0028919756
-
Histone H3 and H4 N-termini interact with Sir3 and Sir4 proteins: A molecular model for the formation of heterochromatin in yeast
-
Hecht, A., Laroche, T., Strahl-Bolsinger, S., Gasser, S. & Grunstein, M. Histone H3 and H4 N-termini interact with Sir3 and Sir4 proteins: a molecular model for the formation of heterochromatin in yeast. Cell 80, 583-592 (1995).
-
(1995)
Cell
, vol.80
, pp. 583-592
-
-
Hecht, A.1
Laroche, T.2
Strahl-Bolsinger, S.3
Gasser, S.4
Grunstein, M.5
-
8
-
-
0027192267
-
Transcriptional silencing in yeast is associated with reduced nucleosomal acetylation
-
Braunstein, M., Rose, A., Holmes, S., Allis, C.D. & Broach, J. Transcriptional silencing in yeast is associated with reduced nucleosomal acetylation. Genes Dev. 7, 592-604 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 592-604
-
-
Braunstein, M.1
Rose, A.2
Holmes, S.3
Allis, C.D.4
Broach, J.5
-
9
-
-
0028304836
-
Silencers and domains of generalized repression
-
Loo, S. & Rine, J. Silencers and domains of generalized repression. Science 264, 1768-1771 (1994).
-
(1994)
Science
, vol.264
, pp. 1768-1771
-
-
Loo, S.1
Rine, J.2
-
10
-
-
0030719974
-
DNA in transcriptionally silenced chromatin assumes a distinct topology that is sensitive to cell cycle progression
-
Bi, X. & Broach, J. DNA in transcriptionally silenced chromatin assumes a distinct topology that is sensitive to cell cycle progression. Mol. Cell. Biol. 17, 7077-7087 (1997).
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7077-7087
-
-
Bi, X.1
Broach, J.2
-
11
-
-
0025201982
-
Position effect at s. Cerevisiae telomeres: Reversible repression of pol 11 transcription
-
Gottschling, D.E. et al. Position effect at S. cerevisiae telomeres: reversible repression of pol 11 transcription. Cell 63, 751-762 (1990).
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
-
12
-
-
0028004378
-
Evidence that a complex of Sir proteins interacts with a silencer and telomere-binding protein RAP1
-
Moretti, P., Freeman, K., Coodly, L. & Shore, D. Evidence that a complex of Sir proteins interacts with a silencer and telomere-binding protein RAP1. Genes Dev. 8, 2257-2269 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 2257-2269
-
-
Moretti, P.1
Freeman, K.2
Coodly, L.3
Shore, D.4
-
13
-
-
0027423154
-
SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres
-
Palladino, F. et al. SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres. Cell 75, 543-555 (1993).
-
(1993)
Cell
, vol.75
, pp. 543-555
-
-
Palladino, F.1
-
15
-
-
0032076127
-
Yeast Ku as a regulator of chromosomal DNA end structure
-
Gravel, S., Larrivee, M., Labrecque, P. & Wellinger, R.J. Yeast Ku as a regulator of chromosomal DNA end structure. Science 280, 741-744 (1998).
-
(1998)
Science
, vol.280
, pp. 741-744
-
-
Gravel, S.1
Larrivee, M.2
Labrecque, P.3
Wellinger, R.J.4
-
16
-
-
0032554793
-
Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres
-
Laroche, T. et al. Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr. Biol. 8, 653-656 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 653-656
-
-
Laroche, T.1
-
17
-
-
0024536650
-
A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA
-
Gottlieb, S. & Esposito, R.E. A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA. Cell 56, 771-776 (1989).
-
(1989)
Cell
, vol.56
, pp. 771-776
-
-
Gottlieb, S.1
Esposito, R.E.2
-
18
-
-
0031044789
-
Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast
-
Bryk, M. et al. Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast. Genes Dev. 11, 255-269 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 255-269
-
-
Bryk, M.1
-
19
-
-
0031056907
-
An unusual form of transcriptional silencing in yeast ribosomal DNA
-
Smith, J.S. & Boeke, J.D. An unusual form of transcriptional silencing in yeast ribosomal DNA. Genes Dev. 11, 241-254 (1997).
-
(1997)
Genes Dev.
, vol.11
, pp. 241-254
-
-
Smith, J.S.1
Boeke, J.D.2
-
20
-
-
0030831573
-
Direct evidence for Sir2 modulation of chromatin structure in yeast rDNA
-
Fritze, C. & Esposito, R. Direct evidence for Sir2 modulation of chromatin structure in yeast rDNA. EMBO J. 16, 6495-6509 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 6495-6509
-
-
Fritze, C.1
Esposito, R.2
-
21
-
-
0028841317
-
The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability
-
Brachmann, C.B. et al. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev. 9, 2888-2902 (1995)
-
(1995)
Genes Dev.
, vol.9
, pp. 2888-2902
-
-
Brachmann, C.B.1
-
22
-
-
0030964526
-
Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
-
Tsukamoto, Y., Kato, J. & Ikeda, H. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388, 900-903 (1997).
-
(1997)
Nature
, vol.388
, pp. 900-903
-
-
Tsukamoto, Y.1
Kato, J.2
Ikeda, H.3
-
23
-
-
0033611465
-
Yeast cell-type regulation of DNA repair
-
Astrom, S.U., Okamura, S.M. & Rine, J. Yeast cell-type regulation of DNA repair. Nature 397, 310 (1999).
-
(1999)
Nature
, vol.397
, pp. 310
-
-
Astrom, S.U.1
Okamura, S.M.2
Rine, J.3
-
24
-
-
0033612189
-
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks
-
Mills, K.D., Sinclair, D.A. & Guarente, L. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. Cell 97, 609-620 (1999).
-
(1999)
Cell
, vol.97
, pp. 609-620
-
-
Mills, K.D.1
Sinclair, D.A.2
Guarente, L.3
-
25
-
-
0033565609
-
Role of yeast SIR genes and mating type in directing DNA double strand breaks to homologous and non-homologous repair paths
-
Lee, H.E., Paques, F., Sylvan, J. & Haber, J. Role of yeast SIR genes and mating type in directing DNA double strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9, 767-770 (1999).
-
(1999)
Curr. Biol.
, vol.9
, pp. 767-770
-
-
Lee, H.E.1
Paques, F.2
Sylvan, J.3
Haber, J.4
-
26
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin, S.G., Laroche, T., Suka, N., Grunstein, M. & Gasser, S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621-633 (1999).
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
27
-
-
0032404350
-
Splitting the ATM: Distinct repair and checkpoint defects in ataxia-telangiectasia
-
Jeggo, P.A., Carr, A.M. & Lehman, A.R. Splitting the ATM: distinct repair and checkpoint defects in ataxia-telangiectasia. Trends Genet. 14, 312-316 (1998).
-
(1998)
Trends Genet.
, vol.14
, pp. 312-316
-
-
Jeggo, P.A.1
Carr, A.M.2
Lehman, A.R.3
-
28
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K. et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749-1784 (1995).
-
(1995)
Science
, vol.268
, pp. 1749-1784
-
-
Savitsky, K.1
-
29
-
-
0029741576
-
Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap1 protein
-
Marcand, S. et al. Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap1 protein. Genes Dev. 10, 1297-1309 (1996).
-
(1996)
Genes Dev.
, vol.10
, pp. 1297-1309
-
-
Marcand, S.1
-
30
-
-
0033574603
-
Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity
-
Straight A.F. et al. Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell 97, 245-256 (1999).
-
(1999)
Cell
, vol.97
, pp. 245-256
-
-
Straight, A.F.1
-
31
-
-
0030738748
-
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
-
Schwab, M., Lutum, A.S. & Seufert, W. Yeast Hct1 is a regulator of Clb2 cyclin proteolysis. Cell 90, 683-693 (1997).
-
(1997)
Cell
, vol.90
, pp. 683-693
-
-
Schwab, M.1
Lutum, A.S.2
Seufert, W.3
-
32
-
-
0030693087
-
CDC20 and CDH1: A family of substrate-specific activators of APC-dependent proteolysis
-
Visintin, R., Prinz, S. & Amon, A CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis. Science 278, 460-463 (1997).
-
(1997)
Science
, vol.278
, pp. 460-463
-
-
Visintin, R.1
Prinz, S.2
Amon, A.3
-
33
-
-
0033614303
-
Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus
-
Visintin, R., Hwang, E. & Amon, A. Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus. Nature 398, 818-823 (1999).
-
(1999)
Nature
, vol.398
, pp. 818-823
-
-
Visintin, R.1
Hwang, E.2
Amon, A.3
-
34
-
-
0033574594
-
Exit from mitosis is triggered by tem1-dependent release of the protein phosphatase Cdc14 from Nucleolar RENT Complex
-
Shou, W. et al. Exit from mitosis is triggered by tem1-dependent release of the protein phosphatase Cdc14 from Nucleolar RENT Complex. Cell 97, 233-244 (1999).
-
(1999)
Cell
, vol.97
, pp. 233-244
-
-
Shou, W.1
-
35
-
-
0033130010
-
Nucleolar Arf sequesters Mdm2 and activates p53
-
Weber, J.D. et al. Nucleolar Arf sequesters Mdm2 and activates p53. Nature Cell Biol. 1, 20-26 (1999).
-
(1999)
Nature Cell Biol.
, vol.1
, pp. 20-26
-
-
Weber, J.D.1
-
36
-
-
0033000482
-
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
-
Zhang, Y. & Xiong, Y. Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53. Mol. Cell 3, 579-591 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 579-591
-
-
Zhang, Y.1
Xiong, Y.2
-
37
-
-
0033617290
-
Pch2 links chromatin silencing to meiotic checkpoint control
-
San-Segundo, P.A. & Roeder, G.S. Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97, 313-324 (1999).
-
(1999)
Cell
, vol.97
, pp. 313-324
-
-
San-Segundo, P.A.1
Roeder, G.S.2
-
38
-
-
0027502061
-
ZIP1 is a synaptonenmal complex protein required for meiotic chromosome synapsis
-
Sym, M., Engebrecht, J. & Roeder, G.S. ZIP1 is a synaptonenmal complex protein required for meiotic chromosome synapsis. Cell 72, 365-378 (1993).
-
(1993)
Cell
, vol.72
, pp. 365-378
-
-
Sym, M.1
Engebrecht, J.2
Roeder, G.S.3
-
39
-
-
0004760134
-
Life span of individual yeast cells
-
Mortimer, R.K. & Johnston, J.R. Life span of individual yeast cells. Nature 183, 1751-1752 (1959).
-
(1959)
Nature
, vol.183
, pp. 1751-1752
-
-
Mortimer, R.K.1
Johnston, J.R.2
-
40
-
-
0031970254
-
Molecular mechanisms of yeast aging
-
Sinclair, D.A., Mills, K. & Guarente, L. Molecular mechanisms of yeast aging. Trends Biol. Sci. 23, 131-134 (1998).
-
(1998)
Trends Biol. Sci.
, vol.23
, pp. 131-134
-
-
Sinclair, D.A.1
Mills, K.2
Guarente, L.3
-
41
-
-
0033214237
-
The Sir2/3/4 complex and Sir2 alone promote longevity in S. cerevisiae by two different mechanisms
-
Kaeberlein, M., McVey, M. & Guarente, L. The Sir2/3/4 complex and Sir2 alone promote longevity in S. cerevisiae by two different mechanisms. Genes Dev. 13, 2570-2580 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 2570-2580
-
-
Kaeberlein, M.1
McVey, M.2
Guarente, L.3
-
42
-
-
0031459980
-
Extrachromosomal rDNA circles - A cause of aging in yeast
-
Sinclair, D.A. & Guarente, L. Extrachromosomal rDNA circles - a cause of aging in yeast. Cell 91, 1033-1042 (1997).
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
43
-
-
0032911048
-
Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae
-
Park, P.U., Defossez, P.A. & Guarente, L. Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae. Mol. Cell. Biol. 19, 3848-3856 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3848-3856
-
-
Park, P.U.1
Defossez, P.A.2
Guarente, L.3
-
44
-
-
0033120871
-
Elimination of replication block protein Fob1 extends the life span of yeast mother cells
-
Defossez, P.A. et al. Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol. Cell 3, 447-455 (1999).
-
(1999)
Mol. Cell
, vol.3
, pp. 447-455
-
-
Defossez, P.A.1
-
45
-
-
0032958799
-
The shuffling of a mortal coil
-
Rothstein, R. & Gangloff, S. The shuffling of a mortal coil. Nature Genet. 22, 4-6 (1999).
-
(1999)
Nature Genet.
, vol.22
, pp. 4-6
-
-
Rothstein, R.1
Gangloff, S.2
-
46
-
-
0030133624
-
A yeast gene product, Fob1 protein, required for both replication fork blocking and recombination hotspot activities
-
Kobayashi, T. & Horiuchi, T. A yeast gene product, Fob1 protein, required for both replication fork blocking and recombination hotspot activities. Genes Cells 1, 465-474 (1996).
-
(1996)
Genes Cells
, vol.1
, pp. 465-474
-
-
Kobayashi, T.1
Horiuchi, T.2
-
47
-
-
0024291357
-
A replication fork barrier at the 3′ end of yeast ribosomal RNA genes
-
Brewer, B.J. & Fangman, W.L. A replication fork barrier at the 3′ end of yeast ribosomal RNA genes. Cell 55, 637-643 (1988).
-
(1988)
Cell
, vol.55
, pp. 637-643
-
-
Brewer, B.J.1
Fangman, W.L.2
-
48
-
-
0033600176
-
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (Sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
-
Frye, R.A. Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (Sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Biochem. Biophy. Res. Commun. 260, 273-279 (1999).
-
(1999)
Biochem. Biophy. Res. Commun.
, vol.260
, pp. 273-279
-
-
Frye, R.A.1
-
49
-
-
0032509302
-
Genome sequence of the nematode C. elegans: A platform for investigating biology
-
C. elegans sequencing consortium. Genome sequence of the nematode C. elegans: a platform for investigating biology Science 282, 2012-2018 (1998).
-
(1998)
Science
, vol.282
, pp. 2012-2018
-
-
-
50
-
-
0032823749
-
The conserved core of a human SIR2 homolog functions in yeast silencing
-
Sherman, J.M. et al. The conserved core of a human SIR2 homolog functions in yeast silencing. Mol. Biol. Cell 10, 3045-3059 (1999).
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3045-3059
-
-
Sherman, J.M.1
-
51
-
-
0343199707
-
Phenotypic switching in Candida Albicans is controlled by a SIR2 gene
-
Perez-Martin, J., Uria, J.A. & Johnson, A.D. Phenotypic switching in Candida Albicans is controlled by a SIR2 gene. EMBO J. 18, 2580-2592 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 2580-2592
-
-
Perez-Martin, J.1
Uria, J.A.2
Johnson, A.D.3
-
52
-
-
0029830552
-
CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required for the lack of nicotinate mononucleotide: 5, 6-Dimethylbenzimidazole phophoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2
-
Tsang, A.W. & Escalante-Semerena, J.C. CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required for the lack of nicotinate mononucleotide: 5, 6-dimethylbenzimidazole phophoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2. J. Bacteriol. 178, 7016-7019 (1996).
-
(1996)
J. Bacteriol.
, vol.178
, pp. 7016-7019
-
-
Tsang, A.W.1
Escalante-Semerena, J.C.2
|