EBR1, a novel Zn2Cys6 transcription factor, affects virulence and apical dominance of the hyphal tip in Fusarium graminearum

Molecular Plant-Microbe Interactions

Volumn 24, Issue 12, 2011, Pages 1407-1418

  Zhao, Chunzhao ^a,b,c   Waalwijk, Cees ^c   De Wit, Pierre J G M ^c,d   Van Der Lee, Theo ^c   Tang, Dingzhong ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c WAGENINGEN UNIVERSITY   (Netherlands)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; GREEN FLUORESCENT PROTEIN; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS; FUNGUS HYPHAE; FUNGUS SPORE; FUSARIUM; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC COMPLEMENTATION; GENETIC TRANSFORMATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; INFLORESCENCE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PATHOGENICITY; PHENOTYPE; PHYLOGENY; PLANT DISEASE; SEQUENCE ALIGNMENT; VIRULENCE; WHEAT;

AMINO ACID SEQUENCE; CELL NUCLEUS; FUNGAL PROTEINS; FUSARIUM; GENE EXPRESSION REGULATION, FUNGAL; GENE KNOCKOUT TECHNIQUES; GENETIC COMPLEMENTATION TEST; GREEN FLUORESCENT PROTEINS; HYPHAE; INFLORESCENCE; MOLECULAR SEQUENCE DATA; PHENOTYPE; PHYLOGENY; PLANT DISEASES; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SPORES, FUNGAL; TRANSCRIPTION FACTORS; TRANSFORMATION, GENETIC; TRITICUM; VIRULENCE; ZINC FINGERS;

FUNGI; GIBBERELLA ZEAE; TRITICUM AESTIVUM;

EID: 81255144863     PISSN: 08940282     EISSN: None     Source Type: Journal    
DOI: 10.1094/MPMI-06-11-0158     Document Type: Article

References (47)

1. 6 binuclear cluster that binds the URS1 DNA sequence in a zinc-dependent manner. Prot. Sci. 4:1832-1843.
2. Bai, G. H., and Shaner, G. 1996. Variation in Fusarium graminearum and cultivar resistance to wheat scab. Plant Dis. 80:975-979.
3. Bai, G. H., Desjardins, A. E., and Plattner, R. D. 2002. Deoxynivalenolnonproducing Fusarium graminearum causes initial infection, but does not cause disease spread in wheat spikes. Mycopathologia 153:91-98. (Pubitemid 34276145)
4. Baldwin, T. K., Urban, M., Brown, N., and Hammond-Kosack, K. E. 2010. A role for topoisomerase I in Fusarium graminearum and F culmorum pathogenesis and sporulation. Mol. Plant-Microbe Interact. 23:566-577.
5. Bluhm, B. H., Zhao, X., Flaherty, J. E., Xu, J. R., and Dunkle, L. D. 2007. RAS2 regulates growth and pathogenesis in Fusarium graminearum. Mol. Plant-Microbe Interact. 20:627-636. (Pubitemid 47011018)
6. Brown, D. W., Butchko, R. A., Busman, M., and Proctor, R. H. 2007. The Fusarium verticillioides FUM gene cluster encodes a Zn (II) 2Cys6 protein that affects FUM gene expression and fumonisin production. Eukaryot. Cell 6:1210-1218. (Pubitemid 47077172)
7. Burger, G., Strauss, J., Scazzocchio, C., and Lang, B. F. 1991. nirA, the pathway-specific regulatory gene of nitrate assimilation in Aspergillus nidulans encodes a putative GAL4-type zinc finger protein and contains four introns in highly conserved regions. Mol. Cell Biol. 11:5746-5755. (Pubitemid 21895342)
8. Chang, P. K., Ehrlich, K. C., Yu, J., Bhatnagar, D., and Cleveland, T. E. 1995. Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis. Appl. Environ. Microbiol. 61:2372-2377.
9. Chenna, R., Sugawara, H., Koike, T., Lopez, R., Gibson, T. J., Higgins, D. G., and Thompson, J. D. 2003. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31:3497-3500. (Pubitemid 37442184)
10. Cuomo, C. A., Guldener, U., Xu, J. R., Trail, F., Turgeon, B. G., Di Pietro, A., Walton, J. D., Ma, L. J., Baker, S. E., Rep, M., Adam, G., Antoniw, J., Baldwin, T., Calvo, S., Chang, Y. L., Decaprio, D., Gale, L. R., Gnerre, S., Goswami, R. S., Hammond-Kosack, K., Harris, L. J., Hilburn, K., Kennell, J. C., Kroken, S., Magnuson, J. K., Mannhaupt, G., Mauceli, E., Mewes, H. W., Mitterbauer, R., Muehlbauer, G., Munsterkotter, M., Nelson, D., O'Donnell, K., Ouellet, T., Qi, W., Quesneville, H., Roncero, M. I., Seong, K. Y., Tetko, I. V., Urban, M., Waalwijk, C., Ward, T. J., Yao, J., Birren, B. W., and Kistler, H. C. 2007. The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization. Science 317:1400-1402. (Pubitemid 47417482)
11. Desjardins, A. E., Hohn, T. M., and McCormick, S. P. 1993. Trichothecene biosynthesis in Fusarium species: Chemistry, genetics, and significance. Microbiol. Rev. 57:595-604. (Pubitemid 23262510)
12. Desjardins, A. E., Proctor, R. H., Bai, G., McCormick, S. P., Shaner, G., Beuchley, G., Hohn, T. M. 1996. Reduced virulence of trichothecenes antibiotic-nonproducing mutants of Gibberella zeae in wheat field tests. Mol. Plant-Microbe Interact. 9:775-781. (Pubitemid 27015799)
13. Desjardins, A. E., Bai, G., Plattner, R. D., and Proctor, R. H. 2000. Analysis of aberrant virulence of Gibberella zeae following transformationmediated complementation of a trichothecene-deficient (Tri5) mutant. Microbiology 146:2059-2068. (Pubitemid 30639281)
14. Dufresne, M., Hua-Van, A., El Wahab, H. A., Ben M'Barek, S., Vasnier, C., Teysset, L., Kema, G. H., and Daboussi, M. J. 2007. Transposition of a fungal miniature inverted-repeat transposable element through the action of a Tc1-like transposase. Genetics 175:441-452. (Pubitemid 46168584)
15. Dufresne, M., van der Lee, T., Ben M'barek, S., Xu, X., Zhang, X., Liu, T., Waalwijk, C., Zhang, W., Kema, G. H., and Daboussi, M. J. 2008. Transposon-tagging identifies novel pathogenicity genes in Fusarium graminearum. Fungal Genet. Biol. 45:1552-1561.
16. Flaherty, J. E., and Woloshuk, C. P. 2004. Regulation of fumonisin biosynthesis in Fusarium verticillioides by a zinc binuclear cluster-type gene, ZFR1. Appl. Environ. Microbiol. 70:2653-2659. (Pubitemid 38657775)
17. Hou, Z., Xue, C., Peng, Y., Katan, T., Kistler, H. C, and Xu, J. R. 2002. A mitogen-activated protein kinase gene (MGV1) in Fusarium graminearum is required for female fertility, heterokaryon formation, and plant infection. Mol. Plant-Microbe Interact. 15:1119-1127. (Pubitemid 36737951)
18. Imazaki, I., Kurahashi, M., Iida, Y., and Tsuge, T. 2007. Fow2, a Zn (II) 2Cys6-type transcription regulator, controls plant infection of the vascular wilt fungus Fusarium oxysporum. Mol. Microbiol. 63:737-753. (Pubitemid 46105899)
19. Jansen, C, von Wettstein, D., Schafer, W, Kogel, K. H., Felk, A., and Maier, F. J. 1005. Infection patterns in barley and wheat spikes inoculated with wild-type and trichodiene synthase gene disrupted Fusarium graminearum. Proc. Natl. Acad. Sci. U. S. A. 102:16892-16897.
20. Jenczmionka, N. J., Maier, F. J., Losch, A. P., and Schafer, W. 2003. Mating, conidiation and pathogenicity of Fusarium graminearum, the main causal agent of the head-blight disease of wheat, are regulated by the MAP kinase gpmk1. Curr. Genet. 43:87-95. (Pubitemid 36748546)
21. Johnston, M. 1987. A model fungal gene regulatory mechanism: The GAL genes of Saccharomyces cerevisiae. Microbiol. Rev. 51:458-476.
22. Kim, J. E., Jin, J., Kim, H., Kim, J. C., Yun, S. H., and Lee, Y. W. 2006. GIP2, a putative transcription factor that regulates the aurofusarin biosynthetic gene cluster in Gibberella zeae. Appl. Environ. Microbiol. 72:1645-1652. (Pubitemid 43271281)
23. Leach, J., Lang, B. R., and Yoder, O. C. 1982. Methods for selection of mutants and in vitro culture of Cochliobolus heterostrophus. J. Gen. Microbiol. 128:1719-1729. (Pubitemid 12001906)
24. Lee, T., Oh, D. W., Kim, H. S., Lee, J., Kim, Y. H., Yun, S. H., and Lee, Y. W. 2001. Identification of deoxynivalenol-and nivalenol-producing chemotypes of Gibberella zeae by using PCR. Appl. Environ. Microbiol. 67:2966-2972. (Pubitemid 33644760)
25. Leslie J., and Summerell B. 2006. The Fusarium Laboratory Manual. Blackwell Publishing, Ames, IA, U. S. A.
26. Makita, T., Katsuyama, Y., Tani, S., Suzuki, H., Kato, N., Todd, R. B., Hynes, M. J., Tsukagoshi, N., Kato, M., and Kobayashi, T. 2009. Inducer-dependent nuclear localization of a Zn (II) (2) Cys (6) transcriptional activator, AmyR, in Aspergillus nidulans. Biosci. Biotechnol. Biochem. 73:391-399.
27. McMullen, M., Jones, R., Gallenberg, D. 1997. Scab of wheat and barley: A re-emerging disease of devastating impact. Plant Dis. 81:1340-1348.
28. Nicholas, K. B., Nicholas, H. B. J., and Deerfield, D. W. I. 1997. Gene-Doc: Analysis and visualization of genetic variation. EMBNEW News 4:14.
29. Oide, S., Moeder, W., Krasnoff, S., Gibson, D., Haas, H., Yoshioka, K., and Turgeon, B. G. 2006. NPS6, encoding a nonribosomal peptide synthetase involved in siderophore-mediated iron metabolism, is a conserved virulence determinant of plant pathogenic ascomycetes. Plant Cell 18:2836-2853. (Pubitemid 44749907)
30. Pan, T., and Coleman, J. E. 1990. GAL4 transcription factor is not a "zinc finger" but forms a Zn (II) 2Cys6 binuclear cluster. Proc. Natl. Acad. Sci. U. S. A. 87:2077-2081.
31. Proctor, R. H., Hohn, T. M., and McCormick, S. P. 1995. Reduced virulence of Gibberella zeae caused by disruption of a trichothecene toxin biosynthetic gene. Mol. Plant-Microbe Interact. 8:593-601.
32. Ramamoorthy, V., X. Zhao, A. K. Snyder, J.-R. Xu, and D. M. Shah. 2007. Two mitogen-activated protein kinase signalling cascades mediate basal resistance to antifungal plant defensins in Fusarium graminearum. Cell Microbiol. 9:1491-1506. (Pubitemid 46774020)
33. Saghai-Maroof, M. A., Soliman, K. M., Jorgensen, R. A., and Allard, R. W. 1984. Ribosomal DNA spacer-length polymorphisms in barley: Mendelian inheritance, chromosomal location, and population dynamics. Proc. Natl. Acad. Sci. U. S. A. 81:8014-8018.
34. Schmid, J., and Harold, F. M. 1988. Dual roles for calcium ions in apical growth of Neurospora crassa. J. Gen. Microbiol. 134:2623-2631.
35. Schultz, J., Milpetz, F., Bork, P., and Ponting, C. P. 1998. SMART, a simple modular architecture research tool: Identification of signaling domains. Proc. Natl. Acad. Sci. U. S. A. 95:5857-5864. (Pubitemid 28248931)
36. Semighini, C. P., and Harris, S. D. 2008. Regulation of apical dominance in Aspergillus nidulans hyphae by reactive oxygen species. Genetics 179:1919-1932.
37. Shim, W.-B., Sagaram, U. S., Choi, Y.-E, So, J., Wilkinson, H. H., and Lee, Y.-W. 2006. FSR1 is essential for virulence and female fertility in Fusarium verticillioides and F graminearum. Mol. Plant-Microbe Interact. 19:725-733.
38. Shimizu, K., Hicks, J. K., Huang, T. P., and Keller, N. P. 2003. Pka, Ras and RGS protein interactions regulate activity of AflR, a Zn (II) 2Cys6 transcription factor in Aspergillus nidulans. Genetics 165:1095-1104. (Pubitemid 38020234)
39. 2+ channel regulates fungal tip growth. J. Cell. Sci. 115:5013-5025. (Pubitemid 36054651)
40. Silverman-Gavrila, L. B., and Lew, R. R. 2003. Calcium gradient dependence of Neurospora crassa hyphal growth. Microbiology 149:2475-2485. (Pubitemid 37160723)
41. Thompson, J. D., Higgins, D. G., and Gibson, T. J. 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673-4680. (Pubitemid 24354800)
42. Turgeon, B. G., Garber, R. C, and Yoder, O. C. 1987. Development of a fungal transformation system based on selection of sequences with promoter activity. Mol. Cell Biol. 7:3297-3305.
43. Vienken, K., Scherer, M., and Fischer, R. 2005. The Zn (II) 2Cys6 putative Aspergillus nidulans transcription factor repressor of sexual development inhibits sexual development under low-carbon conditions and in submersed culture. Genetics 169:619-630. (Pubitemid 40404299)
44. Voigt, C. A., Schafer, W., and Salomon, S. 2005. A secreted lipase of Fusarium graminearum is a virulence factor required for infection of cereals. Plant J. 42:364-375. (Pubitemid 40689557)
45. Wang, Y., Liu, W., Hou, Z., Wang, C., Zhou, X., Jonkers, W., Ding, S., Kistler, H. C, and Xu, J. R. 2011. A novel transcriptional factor important for pathogenesis and ascosporogenesis in Fusarium graminearum. Mol. Plant-Microbe Interact. 24:118-128.
46. Woloshuk, C. P., Foutz, K. R., Brewer, J. F., Bhatnagar, D., Cleveland, T. E., and Payne, G. A. 1994. Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis. Appl. Environ. Microbiol. 60:2408-2414. (Pubitemid 24205740)
47. Yu, J. H., Butchko, R. A., Fernandes, M., Keller, N. P., Leonard, T. J., and Adams, T. H. 1996. Conservation of structure and function of the aflatoxin regulatory gene aflR from Aspergillus nidulans and A. flavus. Curr. Genet. 29:549-555. (Pubitemid 26166756)