Inducer-dependent nuclear localization of a zn(ii)2cys6 transcriptional activator, amyr, in aspergillus nidulans

Bioscience, Biotechnology and Biochemistry

Volumn 73, Issue 2, 2009, Pages 391-399

  Makita, Tomohiro ^a   Katsuyama, Yoko ^a   Tani, Shuji ^a   Suzuki, Hayato ^a   Kato, Naoki ^a   Todd, Richard B ^b   Hynes, Michael J ^b   Tsukagoshi, Norihiro ^a   Kato, Masashi ^a   Kobayashi, Tetsuo ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Amylase; AmyR; Aspergillus; Induction; Nuclear localization

Indexed keywords

AMYLASE; AMYR; ASPERGILLUS; INDUCTION; NUCLEAR LOCALIZATION;

CHEMICAL ACTIVATION; NUCLEIC ACIDS; PHYSIOLOGICAL MODELS; ZINC; ZINC COMPOUNDS;

GENES;

ASPERGILLUS; EMERICELLA NIDULANS;

AMYR PROTEIN, ASPERGILLUS; CYSTEINE; FUNGAL DNA; FUNGAL PROTEIN; HYBRID PROTEIN; ISOMALTOSE; TRANSACTIVATOR PROTEIN; ZINC;

AMINO ACID SEQUENCE; ARTICLE; ASPERGILLUS NIDULANS; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; FUNGAL GENE; GENE DELETION; GENETICS; INTRACELLULAR SPACE; METABOLISM; MOLECULAR GENETICS; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION INITIATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; CELL NUCLEUS; CYSTEINE; DNA, FUNGAL; FUNGAL PROTEINS; GENE DELETION; GENES, FUNGAL; INTRACELLULAR SPACE; ISOMALTOSE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTIONAL ACTIVATION; ZINC;

EID: 65249168752     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.80654     Document Type: Article

References (47)

1. Kaffman, A., and O'Shea, E. K., Regulation of nuclear localization: a key to a door. Annu. Rev. Cell Dev. Biol., 15, 291-339 (1999).
2. O'Neill, E. M., Kaffman, A., Jolly, E. R., and O'Shea, E. K., Regulation of PH04 nuclear localization by the PHO80-PHO85 cyclin-CDK complex. Science, 271, 209-212 (1996).
3. Kaffman, A., Rank, N. M., and O'Shea, E. K., Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Psel/Kapl21. Genes Dev., 12, 2673-2683 (1998).
4. Beg, A. A., Finco, T. S., Nantemet, P. V., and Baldwin, A. S., Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I?Bα: a mechanism for NF?B activation. Mol. Cell. Biol., 13, 3301-3310(1993).
5. Malek, S., Huxford, T., and Ghosh, G., I?Bα functions through direct contact with the nucelar localization signals and the DNA binding sequences of NF-?B. J. Biol. Chem., 273, 25427-25435 (1998).
6. Struhl, G., and Adachi, A., Nuclear access and action of Notch in vivo. Cell, 93, 649-660 (1998).
7. 6 binuclear cluster DNA binding motif. Fungal Genet. Biol., 21, 388-405 (1997).
8. Selleck, S. B., and Majors, J. E., In vivo DNA-binding properties of a yeast transcription activator protein. Mol. Cell. Biol, 7, 3260-3267 (1987).
9. Delahodde, A., Pandjaitan, R., Corral-Debrinski, M., and Jacq, C, Psel/Kapl21-dependent nuclear localization of the major yeast multidrug resistance (MDR) transcription factor Pdrl. Mol. Microbiol, 39, 304-312 (2001).
10. Siddiqui, A. H., and Brandriss, M. C, The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences. Mol. Cell. Biol, 9, 4706-4712 (1989).
11. Kirkpatrick, C. R., and Schimmel, P., Detection of leucine-independent DNA site occupancy of the yeast Leu3p transcriptional activator in vivo. Mol. Cell. Biol, 15, 4021-4030 (1995).
12. Alami, M. E., Feller, A., Pierard, A., and Dubois, E., Characterisation of a tripartite nuclear localisation sequence in the regulatory protein Lysl4 of Saccharomyces cerevisiae. Curr. Genet., 38, 78-86 (2000).
13. Zhang, L., and Guarente, L., HAP1 is nuclear but is bound to a cellular factor in the absence of heme. J. Biol. Chem., 269, 14643-14647 (1994).
14. Pokorska, A., Drevet, C, and Scazzocchio, C, The analysis of the transcriptional activator PrnA reveals a tripartite nuclear localisation sequence. J. Mol. Biol, 298, 585-596 (2000).
15. Nikolaev, I., Cochet, M.-F., and Felenbok, B., Nuclear import of zinc binuclear cluster proteins proceeds through multiple, overlapping transport pathways. Eukaryot. Cell, 2, 209-221 (2003).
16. Hon, T., Hach, A., Tamalis, D., Zhu, Y., and Zhang, L., The yeast heme-responsive transcriptional activator Hapl is a preexisting dimer in the absence of heme. J. Biol. Chem., 274, 22770-22774 (1999).
17. 6 activator with a unique DNA recognition mode, requires inducer for in vitro binding. Mol. Microbiol, 44, 585-597 (2002).
18. Bhat, J. P., and Murthy, T. V. S., Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction. Mol. Microbiol, 40, 1059-1066 (2001).
19. Wang, D., Zheng, F., Holmberg, S., and Kohlhaw, G. B., Yeast transcriptional regulator Leu3: self-masking, specificity of masking, and evidence for regulation by the intracellular level of Leu3p. J. Biol. Chem., 274, 19017-19024 (1999).
20. 6 transcription factor in Aspergillus nidulans. Genetics, 165, 1095-1104 (2003).
21. Berger, H., Pachlinger, R., Morozov, I., Goller, S., Narendja, F., Caddick, M., and Strauss, J., The GATA factor AreA regulates localization and in vivo binding site occupancy of the nitrate activator NirA. Mol. Microbiol, 59, 433-436 (2006).
22. Tsukagoshi, N., Kobayashi, T., and Kato, M., Regulation of the amylolytic and (hemi-)cellulolytic genes in aspergilli. J. Gen. Appl. Microbiol, 47, 1-19 (2001).
23. Kato, N., Suyama, S., Shirokane, M., Kato, M., Kobayashi, T., and Tsukagoshi, N., Novel α-glucosidase from Aspergillus nidulans with strong transglycosylation activity. Appl. Environ. Microbiol, 68, 1250-1256 (2002).
24. Kato, N., Murakoshi, Y., Kato, M., Kobayashi, T., and Tsukagoshi, N., Isomaltose formed by α-glucosidases triggers amylase induction in Aspergillus nidulans. Curr. Genet., 42, 43-50 (2002).
25. Petersen, K. L., Lehmbeck, J., and Christensen, J., A new transcriptional activator for amylase genes in Aspergillus. Mol. Gen. Genet., 262, 668-676 (1999).
26. Gomi, K., Akeno, T., Minetoki, T., Ozeki, K., Kumagai, C, and Iimura, Y., Molecular cloning and characterization of a transcriptional activator gene, amyR, involved in the amylolytic gene expression in Aspergillus oryzae. Biosci. Biotechnol Biochem., 64, 816-827 (2000).
27. Tani, S., Katsuyama, Y., Hayashi, T., Suzuki, H., Kato, M., Gomi, K., Kobayashi, T., and Tsukagoshi, N., Characterization of the amyR gene encoding a transcriptional activator for the amylase genes in Aspergillus nidulans. Curr. Genet., 39, 10-15 (2001).
28. Tani, S., Itoh, T., Kato, M., Kobayashi, T., and Tsukagoshi, N., In vivo and in vitro analyses of the AmyR binding site of the Aspergillus nidulans agdA promoter; requirement of the CGG direct repeat for induction and high affinity binding of AmyR. Biosci. Biotechnol. Biochem., 65, 1568-1574 (2001).
29. 8AGG sequence in the Aspergillus oryzae taaG2 promoter. Biosci. Biotechnol. Biochem., 68, 1906-1911 (2004).
30. Nakamura, T., Makita, T., Maeda, Y., Tanoue, N., Kato, M., and Kobayashi, T., Expression profile of amylolytic genes in Aspergillus nidulans. Biosci. Biotechnol. Biochem., 70, 2363-2370 (2006).
31. Rowlands, R. T., and Turner, G., Nuclear and extranuclear inheritance of oligomycin resistance in Aspergillus nidulans. Mol. Gen. Genet., 126, 201-206 (1973).
32. Ballance, D. J., and Turner, G., Development of a high-frequency transforming vector for Aspergillus nidulans. Gene, 36, 321-331 (1985).
33. Niwa, Y., Hirano, T., Yoshimoto, K., Shimizu, M., and Kobayashi, H., Non-invasive quantitative detection and applications of non-toxic, S65T-type green fluorescent protein in living plants. Plant J., 18, 455-463 (1999).
34. Gems, D., Johnstone, I. L., and Clutterbuck, A. J., An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene, 98, 61-67 (1991).
35. Higuchi, R., Recombinant PCR. In "PCR Protocols: A Guide to Methods and Applications," eds. Innis, M. A., Gelfand, D. H., Sininsky, J. J., and White, T. J., Academic Press, San Diego, pp. 177-183 (1990).
36. Kato, M., Hayashi, K., Kobayashi, T., and Tsukagoshi, N., A simple and rapid method for the preparation of a cell-free extract with CCAAT-binding activity from filamentous fungi. Biosci. Biotechnol. Biochem., 64, 455-457 (2000).
37. Walker, G. R., Feather, K. D., Davis, P. D., and Hines, K. K., SuperSignal CL-HRP: a new enhanced chemiluminescent substrate for the development of the horseradish peroxidase label in Western blotting applications. J. NIH Res., 7, 76 (1995).
38. Tsukagoshi, N., Furusawa, M., Nagaba, H., Kirita, N., Tuboi, A., and Udaka, S., Isolation of a cDNA encoding Aspergillus oryzae Taka-amylase A: evidence for multiple related genes. Gene, 84, 319-327 (1989).
39. Flipphi, M., Kocialkowska, J., and Felenbok, B., Characteristics of physiological inducers of the ethanol utilization (alc) pathway in Aspergillus nidulans. Biochem. J., 364, 25-31 (2002).
40. Tani, S., Kawaguchi, T., Kato, M., Kobayashi, T., and Tsukagoshi, N., A novel nuclear factor SREB binds to a cis-acting element SRE, required for inducible expression of the Aspergillus oryzae Taka-amylase A Gene in A. nidulans. Mol. Gen. Genet., 263, 232-238 (2000).
41. Chang, Y. S. M., Dubin, R. A., Perkins, E., Forrest, D., Michels, C. A., and Needleman, R. B., MAL63 codes for a positive regulator of maltose fermentation in Saccharomyces cerevisiae. Curr. Genet., 14, 201-209 (1988).
42. Bernreiter, A., Ramon, A., Fernandez-Martinez, J., Berger, H., Araujo-Bazan, L., Espeso, E. A., Pachlinger, R., Gallmetzer, A., Anderl, I., Scazzocchio, C, and Strauss, J., Nuclear export of the transcription factor NirA is a regulatory checkpoint for nitrate induction in Aspergillus nidulans. Mol. Cell. Biol., 27, 791-802 (2007).
43. Peñalva, M. A., and Arst, H. N., Jr., Regulation of gene expression by ambient pH in filamentous fungi and yeasts. Microbiol. Mol. Biol. Rev., 66, 426-446 (2002).
44. Danzi, E. S., Bali, M., and Michels, C. A., Clustered-charge to alanine scanning mutagenesis of the Mal63 MAL-activator C-terminal regulatory domain. Curr. Genet., 44, 173-183 (2003).
45. Ran, F., Bali, M., and Michels, C. A., Hsp90/Hsp70 chaperone machine regulation of the Saccharomyces MAL-activator as determined in vivo using noninducible and constitutive mutant alleles. Genetics, 179, 331-343 (2008).
46. Pratt, W. B., and Toft, D. O., Regulation of signaling protein function and trafficking by the hsp90/hsp70-based cahaperone machinery. Exp. Biol. Med., 228, 111-133 (2003).
47. Yang, J., and DeFranco, D. B., Assessment of glucocorticoid receptor-heat shock protein 90 interactions in vivo during nucleocytoplasmic trafficking. Mol. Endocrinol., 10, 3-13 (1996).