Two mitogen-activated protein kinase signalling cascades mediate basal resistance to antifungal plant defensins in Fusarium graminearum

Cellular Microbiology

Volumn 9, Issue 6, 2007, Pages 1491-1506

  Ramamoorthy, Vellaisamy ^a   Zhao, Xinhua ^b   Snyder, Anita K ^a   Xu, Jin Rong ^b   Shah, Dilip M ^a  

^a DONALD DANFORTH PLANT SCIENCE CENTER   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN MSDEF1; PROTEIN MSDEF4; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; CONTROLLED STUDY; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS GROWTH; FUNGUS ISOLATION; FUNGUS MUTANT; FUSARIUM GRAMINEARUM; HYPEROSMOTIC STRESS; MOLECULAR DYNAMICS; NONHUMAN; PLASMID; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TOMATO; WHEAT;

DEFENSINS; FUNGAL PROTEINS; FUSARIUM; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MEDICAGO SATIVA; MEDICAGO TRUNCATULA; MUTATION; PLANT DISEASES; PLANT PROTEINS; TRANSFORMATION, GENETIC;

FUNGI; GIBBERELLA ZEAE; LYCOPERSICON ESCULENTUM; MEDICAGO; TRITICUM AESTIVUM;

EID: 34248646785     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2006.00887.x     Document Type: Article

References (47)

1. Broekaert, W.F., Terras, F.R.G., Cammue, B.P.A., and Vanderleyden, J. (1990) An automated quantitative assay for fungal growth inhibition. FEMS Microbiol Lett 69: 55-59.
2. Broekaert, W.F., Terras, F.R.G., Cammue, B.P.A., and Osborn, R.W. (1995) Plant defensins: Novel antimicrobial peptides as components of the host defense system. Plant Physiol 108: 1353-1358.
3. Cammue, B.P.A., De Bolle, M.F., Terras, F.R., Proost, P., Van Damme, J., Rees, S.B., et al. (1992) Isolation and characterization of a novel class of plant antimicrobial peptides form Mirabilis jalapa L. seeds. J Biol Chem 267: 2228-2233.
4. Cappelini, R.A., and Peterson, J.L. (1965) Macroconidium formation in submerged cultures by a non-sporulating strain of Gibberella zeae. Mycologia 57: 962-966.
5. Carroll, A.M., Sweigard, J.A., and Valent, B. (1994) Improved vectors for selecting resistance to hygromycin. Fungal Genet Newsl 41: 22.
6. Catlett, N.L., Lee, B.N., Yoder, O.C., and Turgeon, B.G. (2003) Split-marker recombination for efficient targeted deletion of fungal genes. Fungal Genet Newsl 50: 9-11.
7. Correll, J.C., Klittich, C.J.R., and Leslie, J.F. (1987) Nitrate nonutilizing mutants of Fusarium oxysporum and their use in vegetative compatibility tests. Phytopathology 77: 1640-1646.
8. Cullen, P.J., Schultz, J., Horecka, J., Stevenson, B.J., Jigami, Y., and Sprague, G.F., Jr (2000) Defects in protein glycosylation cause SHO1 -dependent activation of a STE12 signaling pathway in yeast. Genetics 155: 1005-1018.
9. Di Pietro, A., Garcia-MacEira, F.I., Meglecz, E., and Roncero, M.I. (2001) A MAP kinase of the vascular wilt fungus Fusarium oxysporum is essential for root penetration and pathogenesis. Mol Microbiol 39: 1140-1452.
10. Dixon, K.P., Xu, J.R., Smirnoff, N., and Talbot, N.J. (1999) Independent signaling pathways regulate cellular turgor during hyperosmotic stress and appressorium-mediated plant infection by Magnaporthe grisea. Plant Cell 11: 2045-2058.
11. Gao, A.G., Hakimi, S.M., Mittanck, C.A., Wu, Y., Woerner, B.M., Stark, D.M., et al. (2000) Fungal pathogen protection in potato by expression of a plant defensin peptide. Nat Biotechnol 18: 1307-1310.
12. Goswami, R.S., and Kistler, H.C. (2004) Heading for disaster: Fusarium graminearum on cereal crops. Mol Plant Pathol 5: 515-525.
13. Gustin, M.C., Albertyn, J., Alexander, M., and Davenport, K. (1998) MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62: 1264-1300.
14. Hanks, J.N., Snyder, A.K., Graham, M.A., Shah, R.K., Blaylock, L.A., Harrison, M.J., and Shah, D.M. (2005) Defensin gene family in Medicago truncatula: Structure, expression and induction by signal molecules. Plant Mol Biol 58: 385-399.
15. Heinisch, J.J., Lorberg, A., Schmitz, H.P., and Jacoby, J.J. (1999) The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae. Mol Microbiol 32: 671-680.
16. Hohn, T.M., and Desjardins, A.E. (1992) Isolation and gene disruption of the Tox5 gene encoding trichodiene synthase in Gibberella pulicaris. Mol Plant Microbe Interact 5: 249-256.
17. Hou, Z., Xue, C., Peng, Y., Katan, T., Kistler, H.C., and Xu, J.R. (2002) A mitogen-activated protein kinase gene (MGV1) in Fusarium graminearum is required for female fertility, heterokaryon formation, and plant infection. Mol Plant Microbe Interact 15: 1119-1127.
18. Jenczmionka, N.J., and Schafer, W. (2005) The Gpmk1 MAP kinase of Fusarium graminearum regulates the induction of specific secreted enzymes. Curr Genet 47: 29-36.
19. Jenczmionka, N.J., Maier, F.J., Losch, A.P., and Schafer, W. (2003) Mating, conidiation and pathogenicity of Fusarium graminearum, the main causal agent of the head-blight disease of wheat, are regulated by the MAP kinase gpmk1. Curr Genet 43: 87-95.
20. Kahmann, R., and Kamper, J. (2004) Ustilago maydis: How its biology relates to pathogenic development. New Phytol 164: 31-42.
21. Kojima, K., Kikuchi, T., Takano, Y., Oshiro, E., and Okuno, T. (2002) The mitogen-activated protein kinase gene MAF1 is essential for the early differentiation phase of appressorium formation in Colletotrichum lagenarium. Mol Plant Microbe Interact 15: 1268-1276.
22. Kojima, K., Takano, Y., Yoshimi, A., Tanaka, C., Kikuchi, T., and Okuno, T. (2004) Fungicide activity through activation of a fungal signalling pathway. Mol Microbiol 53: 1785-1796.
23. Kojima, K., Bahn, Y.S., and Heitman, J. (2006) Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans. Microbiology 152: 591-604.
24. Lay, F.T., and Anderson, M.A. (2005) Defensins-components of the innate immune system in plants. Curr Protein Pept Sci 6: 85-101.
25. Lengeler, K.B., Davidson, R.C., D'Souza, C., Harashima, T., Shen, W.C., Wang, P., et al. (2000) Signal transduction cascades regulating fungal development and virulence. Microbiol Mol Biol Rev 64: 746-785.
26. Lev, S., and Horwitz, B.A. (2003) A mitogen-activated protein kinase pathway modulates the expression of two cellulase genes in Cochliobolus heterostrophus during plant infection. Plant Cell 15: 835-844.
27. Mehrabi, R., Van der Lee, T., Waalwijk, C., and Kema, G.H.J. (2006) MgSlt2, a cellular integrity MAP kinase gene of the fungal wheat pathogen Mycosphaerella graminicola, is dispensable for penetration but essential for invasive growth. Mol Plant Microbe Interact 19: 389-398.
28. Pandey, A., Roca, M.G., Read, N.D., and Glass, N.L. (2004) Role of a mitogen-activated protein kinase pathway during conidial germination and hyphal fusion in Neurospora crassa. Eukaryot Cell 3: 348-358.
29. Ruiz-Roldan, M.C., Maier, F.J., and Schafer, W. (2001) PTK1, a mitogen-activated-protein kinase gene, is required for conidiation, appressorium formation, and pathogenicity of Pyrenophora teres on barley. Mol Plant Microbe Interact 14: 116-125.
30. Sambrook, J., and Russell, D.W. (2001) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
31. Seong, K., Hou, Z., Tracy, M., Kistler, H.C., and Xu, J.R. (2005) Random insertional mutagenesis identifies genes associated with virulence in the wheat scab fungus Fusarium graminearum. Phytopathology 95: 744-750.
32. da Silva Conceicao, A., and Broekaert, W.F. (1999) Plant defensins. In Pathogenesis-Related Proteins in Plants. Datta, S.K., and Muthukrishnan, S. (eds). New York: CRC Press, pp. 247-260.
33. Solomon, P.S., Waters, O.D., Simmonds, J., Cooper, R.M., and Oliver, R.P. (2005) The Mak2 MAP kinase signal transduction pathway is required for pathogenicity in Stagonospora nodorum. Curr Genet 48: 60-68.
34. Spelbrink, R.G., Dilmac, N., Allen, A., Smith, T.J., Shah, D.M., and Hockerman, G.H. (2004) Differential antifungal and calcium channel-blocking activity among structurally related plant defensins. Plant Physiol 135: 2055-2067.
35. Terras, F.R., Schoofs, H.M.E., De Bolle, M.F.C., Van Leuven, F., Rees, S.B., Vanderleyden, J., et al. (1992) Analysis of two novel classes of plant antifungal proteins from radish (Raphanus sativus L.) seeds. J Biol Chem 267: 15301-15309.
36. Thevissen, K., Cammue, B.P.A., Lemaire, K., Winderickx, J., Dickson, R.C., Lester, R.L., et al. (2000) A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii). Proc Natl Acad Sci USA 97: 9531-9536.
37. Thevissen, K., Warnecke, D.C., Francois, I.E.J.A., Leipelt, M., Heinz, E., Ott, C., et al. (2004) Defensins from insects and plants interact with fungal glucosylceramides. J Biol Chem 279: 3900-3905.
38. Thevissen, K., Francois, I.E., Aerts, A.M., and Cammue, B.P.A. (2005) Fungal sphingolipids as targets for the development of selective antifungal therapeutics. Curr Drug Targets 6: 923-928.
39. Thomma, B.P.H.J., Cammue, B.P.A., and Thevissen, K. (2002) Plant defensins. Planta 216: 193-202.
40. Urban, M., Mott, E., Farley, T., and Hammond-Kosack, K. (2003) The Fusarium graminearum MAP1 gene is essential for pathogenicity and development of perithecia. Mol Plant Pathol 4: 347-359.
41. Xu, J.R. (2000) Map kinases in fungal pathogens. Fungal Genet Biol 31: 137-152.
42. Xu, J.R., and Hamer, J.E. (1996) MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev 10: 2696-2706.
43. Xu, J.R., and Leslie, J.F. (1996) A genetic map of Gibberella fujikuroi mating population A (Fusarium moniliforme). Genetics 143: 175-189.
44. Xu, J.R., Staiger, C.J., and Hamer, J.E. (1998) Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses. Proc Natl Acad Sci USA 95: 12713-12718.
45. Xue, C., Park, G., Choi, W., Zheng, L., Dean, R.A., and Xu, J.R. (2002) Two novel fungal virulence genes specifically expressed in appressoria of the rice blast fungus. Plant Cell 14: 2107-2119.
46. Zhang, Y., Lamm, R., Pillonel, C., Lam, S., and Xu, J.R. (2002) Osmoregulation and fungicide resistance: The Neurospora crassa os-2 gene encodes a HOG1 mitogen-activated protein kinase homologue. Appl Environ Microbiol 68: 532-538.
47. Zhao, X., Kim, Y., Park, G., and Xu, J.R. (2005) A mitogen-activated protein kinase cascade regulating infection-related morphogenesis in Magnaporthe grisea. Plant Cell 17: 1317-1329.