Chromosome and DNA damage analysis in individuals occupationally exposed to pesticides with relation to genetic polymorphism for CYP 1A1gene in Ecuador

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 562, Issue 1-2, 2004, Pages 77-89

  Paz Y Miño, Cesar ^a   Arévalo, Melissa ^a   Sanchez, María Eugenia ^a   Leone, Paola E ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DEL ECUADOR   (Ecuador)

Author keywords

Comet assay; CYP 1A1; Gene; Pesticides

Indexed keywords

DNA; PESTICIDE;

ADULT; ALLELE; ARTICLE; CELL NUCLEUS; CHROMOSOME ABERRATION; CHROMOSOME DAMAGE; COMET ASSAY; CONTROLLED STUDY; CYTOCHROME P450 1A1 GENE; DNA DAMAGE; ECUADOR; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTOXICITY; HUMAN; MALE; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; OCCUPATIONAL TOXICOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL SIGNIFICANCE;

CHROMOSOME ABERRATIONS; COMET ASSAY; CYTOCHROME P-450 CYP1A1; DNA DAMAGE; ECUADOR; FEMALE; GENOTYPE; HUMANS; MALE; OCCUPATIONAL EXPOSURE; PESTICIDES; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 3242763896     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.05.005     Document Type: Article

References (52)

1. Dulout F.N., Pastori M.C., Olivero O.A., Gonzalez Cid M., Loria D., Matos E., Sobel N., de Bujan E.C., Albiano N. Sister-chromatid exchanges and chromosomal aberrations in a population exposed to pesticides. Mutat. Res. 143:1985;237-244
2. Paz-y-Miño C., Bustamante G., Sánchez M.E., Leone P.E. Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador. Environ. Health Perspect. 110(11):2002a;1077-1085
3. Lioi M.B., Scarfi M.R., Santoro A., Barbieri R., Zeni O., Di Berardino D., Ursini M.V. Genotoxicity and oxidative stress induced by pesticide exposure in bovine lymphocyte cultures in vitro. Mutat. Res. 403:1998;13-20
4. Dahlhaus M., Almstadt E., Henschke P., Luttgert S., Apple K.E. Induction of 8-hydroxyl-2-deoxyguanosine and single-strand break in DNA of V79 cells by tetrachloro-p-hydroquinone. Mutat. Res. 329:1995;29-36
5. Petrovská H., Dušinska M. Oxidative DNA damage in human cells induced by Paraquat. ATLA. 27:1999;387-395
6. C. Castelnouvo, A. Castelnouvo, J. Oviedo, X. Santacruz [on line], Ecuador Trabajo Infantil en la Floricultura: Una Evaluación Rápida, Organización Internacional del Trabajo Programa Internacional para la Erradicación del Trabajo Infantil (IPEC), Ginebra, 2000, available in: http://www.ilo.org/public/spanish/standards/ipec/simpoc/ ecuador/ra/flowers.pdf.
7. Pilinskaya M.A. Cytogenetic effect of the herbicide 2,4-D on human and animal chromosomes. Cytol. Genet. (Tsitologiya I Genetika). 8(3):1974;6-10
8. Falck G.C.M., Hirvonen A., Scarpato R., Saarokoski S.T., Migliore L., Norppa H. Micronuclei in blood lymphocytes and genetic polymorphism for GSTM1, GSTT1 and NAT2 in pesticide-exposed greenhouse workers. Mutat. Res. 441:1999;225-237
9. Rabello N.M., Becak W., de Almeida W.F., Pigati P., Húngaro M.T., Murata T., Percira C.A.B. Cytogenetic study on individuals occupationally exposed to DDT. Mutat. Res. 28:1975;449-454
10. Nehéz M., Berecsi G., Páldy A., Selypes A., Czeizel A., Szentesi I., Csakó J., Levay K., Maurer J., Nagy E. Data on the chromosome examinations of workers exposed to pesticides. Regul. Toxicol. Pharmacol. 1:1981;116-122
11. Páldy A., Puskás N., Vincze K., Hadházi M. Cytogenetic studies on rural populations exposed to pesticides. Mutat. Res. 187:1987;127-132
12. Jablonická A., Poláková H., Karelová J., Varqová M. Analysis of chromosome aberrations and sister-chromatid exchanges in peripheral blood lymphocytes of workers with occupational exposure to the mancozeb-containing fungicide Novozir Mn 80. Mutat. Res. 224(2):1989;143-146
13. Joksić G., Vidaković A., Spasojević-Tišma V. Cytogenetic monitoring of pesticide sprayers. Environ. Res. 75:1997;113-118
14. Scarpato R., Hirvonen A., Migliore L., Falck G., Norppa H. Influence of GSTM1 and GSTT1 polymorphisms on the frequency of chromosome aberrations in lymphocytes of smokers and pesticide-exposed greenhouse workers. Mutat. Res. 389:1997;227-235
15. Antonucci G.A., de Syllos Cólus I.M. Chromosomal aberrations in a Brazilian population exposed to pesticides. Teratog. Carcinog. Mutagen. 20(5):2000;265-272
16. Carbonell E., Valbuena A., Xamena N., Creus A., Marcos R. Temporary variations in chromosomal aberrations in a group of agricultural workers exposed to pesticides. Mutat. Res. 344:1995;127-134
17. Garaj-Vrhovac V., Zeljezic D. Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay Pesticide genotoxicity revealed by comet assay. Mutat. Res. 469:2000;279-285
18. Lebailly P., Vigreux C., Lechevrel C., Ledememey D., Godart T., Sichel F., Le Talaër J.Y., Henry-Amar M., Gauduchon P. DNA damage in mononuclear leukocytes of farmers measured using the alkaline comet assay: discussion of critical parameters and evaluation of seasonal variations in relation to pesticides exposure. Cancer Epidemol. Biomarkers Prev. 7:1998a;917-927
19. Lebailly P., Vigreux C., Lechevrel C., Ledememey D., Godart T., Sichel F., Le Talaër J.Y., Henry-Amar M., Gauduchon P. DNA damage in mononuclear leukocytes of farmers measured using the alkaline comet assay: modifications of DNA damage levels after a one-day field spraying period with selected pesticides. Cancer Epidemol. Biomarkers Prev. 7:1998;929-940
20. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 175:1988;184-191
21. Raunio H., Husgafvel-Pursiainen K., Anttilas S., Hietanen E., Hirvonen A., Pelkonen O. Diagnosis of polymorphism in carcinogen-activating and innactivating enzymes and cancer susceptibility - a review. Gene. 159:1995;113-121
22. Nebert D.W., Dieter M.Z. The evolution of drug metabolism. Pharmacology. 61:2000;124-135
23. Quiñones L., Berthou F., Varela N., Simon B., Gil L., Lucas D. Ethnic suceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations. Cancer Lett. 141:1999;167-171
24. Omura T. Forty years of Cytochrome P450. Biochem. Biophys. Res. Commun. 266:1999;690-698
25. Sarmanová J., Benešová K., Gut I., Nedelcheva-Kristensen V., Týnková L., Soucek P. Genetic polymorphism of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's Lymphoma. Hum. Mol. Genet. 10(12):2001;1265-1273
26. Larsen S., Williams A. Transplacental exposure to indole-3-carbinol induces sex specific expression of CYP1A1 and CYP1B2 in the liver of fisher 344 neonatal rats. Toxicol. Sci. 64:2001;162-168
27. Kiss I., Sandor J., Pajkos G., Bogner B., Ilededus G., Ember I. Colorectal Cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1 and glutatione-S-transferase M1 enzymes. Anticancer Res. 20:2000;519-522
28. J. Sambrook, E.F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, New York, USA, 1989.
29. Paz-y-Miño C., Davalos V., Sánchez M.E., Arevalo M., Leone P.E. Should gaps be included in chromosomal aberration analysis? Evidence based on the comet assay. Mutat. Res. 516:2002;57-61
30. Chan D.K.Y., Mellick G.O., Buchanan D.D., Hung W.T., Ng P.W., Woo J., Kay R. Lack of association between CYP 1A1 polymorphism and Parkinson's disease in a Chinese population. J. Neural Transm. 109:2002;35-39
31. Kawajiri K., Nakachi K., Imai K., Yoshii A., Shinoda N., Wanatabe J. Identification of genetically high risk individuals to lung cancer by DNA polymorphism of the cytochrome P450 1A1 gene. FEBS Lett. 263:1990;131-133
32. W.K. Kaufman, Pathways of human all post-replication repair, Carcinogenesis, 1989, pp. 1-11.
33. Rupa D.S., Reddi P.P., Reddi O.S. Clastogenic effect of pesticides in peripheral lymphocytes of cotton-field workers. Mutat. Res. 261:1991;177-180
34. C.H. Sierra-Torres, N. Cajas Salazar, L.S. Hoyos, L.S. Zuleta, E.B. Whorton, W.W. Au, In vitro and in vivo genotoxic activity of miral, an organophosphorus insectidic used in Colombia, Mutat. Res. (1998) 56-57.
35. Garaj-Vrhovac V., Zeljezic D. Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay Pesticide genotoxicity revealed by comet assay. Mutat. Res. 469:2000;279-285
36. Bagchi D., Bagchi M., Hassoun E.A., Stohs S.J. In vitro and in vivo generation of reactive oxygen species. Toxicology. 104:1995;129-140
37. Dahlhaus M., Almstadt E., Henschke P., Luttgert S., Apple K.E. Induction of 8-hydroxu-2-deoxyguanosine and single-strand break in DNA of V79 cells by tetrachloro-p-hydroquinone. Mutat. Res. 329:1995;29-36
38. Petrovská H., Dušinska M. Oxidative DNA damage in human cells induced by Paraquat. ATLA. 27:1999;387-395
39. Šram R.J., Podrazilova K., Dejmek J., Mraèoba G., Pilèik T. Single cell gel eletrophoresis assay: sensitivity of peripheral blood cells in human population studies. Mutagenesis. 13:1998;99-103
40. Hartmann A., Herkommer K., Glück M., Speit G. DNA-damaging effect of Cyclophosphamide on human blood cells in vivo and in vitro studies with the single-cell gel test (comet assay). Environ. Mol. Mutagen. 25:1995;180-187
41. Quiñones L., Lucas D., Godoy J., Cáceres D., Berthou F., Varela N., Lee K., Acevedo C., Martínez L., Aguilera A.M., Gu L. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms the effect of single and combined genotypes on lung cancer susceptibility in Chilean people. Cancer Lett. 174:2001;25-44
42. Wong T.K., Everson R.B., Hsu S.T. Potent induction of human placental monoxygenase activity by previous dietary exposure to polychlorinated byphenyls and their termal degradation products. Lancet. 1:1987;721-724
43. Lucier G.W., Nelson K.G., Everson R.B., Wong T.K., Philpot R.M., Tierman T., Taylor M., Sunahara G.I. Placental markers of human exposure to polychlorinated byphenyls and polychlorinated dibenzofurand. Environ. Health Perpect. 76:1987;79-87
44. Pereg D., De Wailly E., Poirier G.G., Ayotte P. Environmental exposure to polychlorinated biphenyls and placental CYP 1A1 activity in Iniut women from Northern Québec. Environ. Health Perpect. 11(6):2002;607-612
45. Arinç E., Sen A., Bozcaarmutlu A. Cytochrome P450 1A and associated mixed-function oxidase induction in fish as a biomarker for toxic carcinogenic polutants in the aquatic environment. Pure Appl. Chem. 72(6):2000;985-994
46. Basham V.M., Pharoah P.D., Healey C.S., Lieben C.S., Day N.E., Easton D.F., Donder B.A.J., Dunning A.M. Polymorphisms in CYP1A1 and smoking: no association with breast cancer risk. Carcinogenesis. 22(11):2001;1797-1800
47. Muñoz S., Vollrath V., Vallejos M.P., Miguel J.F., Covarrubias C., Raddatz A., Chianale J. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the south Amerindian population of Chile. Pharmacogenetics. 8:1998;343-351
48. Kvitko K., Nunes J.C.B., Weimer T.A., Salzano F.M., Hutz M.H. Cytochrome P4501A1 polymorphisms in South American Indians. Hum. Biol. 72(6):2000;1039-1043
49. Cartensen U., Alexandrie A.K., Högstedt B., Rannug A., Bratt I., Hagmar L. B- and T-lymphocyte micronuclei in chimney sweeps with respect to genetic polymorphism for CYP1A1 and GST1 (class Mu). Mutat. Res. 289:1993;187-195
50. Nerurkar P.V., Okinaka L., Aoki C., Seifried A., Lum-Jones A., Wilkens L.R., Marchand L.L. CYP1A1, GSTM1 and GSTP1 genetic polymorphisms and urinary 1-hydroxypyrene excretion in non-occupationally exposed individuals, Cancer Epidemiology. Biomarkers Prev. 9:2000;1119-1122
51. Garte S. Metabolic susceptibility genes as cancer risk factors: time for a reassessment? Cancer Epidemiol. Biomarkers Prev. 10:2001;1233-1237
52. WHO, The WHP Recommended Classification of Pesticides by Hazard and Guidelines to Classification 2001-2002, World Health Organization Programme on Chemical Safety, Geneva, 2001.