Challenges in the identification of MSH6-associated colorectal cancer: Rectal location, less typical histology, and a subset with retained mismatch repair function

American Journal of Surgical Pathology

Volumn 35, Issue 9, 2011, Pages 1391-1399

  Klarskov, Louise ^a   Holck, Susanne ^a   Bernstein, Inge ^b   Okkels, Henrik ^c   Rambech, Eva ^d   Baldetorp, Bo ^d   Nilbert, Mef ^a,d  

^a HVIDOVRE HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d LUND UNIVERSITY   (Sweden)

Author keywords

histopathology; HNPCC; immunohistochemistry; lynch syndrome; microsatellite instability

Indexed keywords

DNA BINDING PROTEIN; G T MISMATCH BINDING PROTEIN; G-T MISMATCH-BINDING PROTEIN; MLH1 PROTEIN, HUMAN; MSH2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN MSH2; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER;

AGE; AGED; ARTICLE; CANCER STAGING; CHEMISTRY; CHI SQUARE DISTRIBUTION; DENMARK; FEMALE; GENETIC PREDISPOSITION; GENETICS; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MISMATCH REPAIR; MUTATION; NECROSIS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHENOTYPE; PREDICTIVE VALUE; RECTUM; REGISTER; TUMOR ASSOCIATED LEUKOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGE FACTORS; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DENMARK; DNA MISMATCH REPAIR; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTATION; MUTS HOMOLOG 2 PROTEIN; NECROSIS; NEOPLASM STAGING; NUCLEAR PROTEINS; PHENOTYPE; PREDICTIVE VALUE OF TESTS; RECTUM; REGISTRIES; TUMOR MARKERS, BIOLOGICAL;

EID: 81155162622     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e318225c3f0     Document Type: Article

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