Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers

Journal of Medical Genetics

Volumn 47, Issue 9, 2010, Pages 579-585

  Sjursen, Wenche ^a,b   Haukanes, Bjørn Ivar ^c   Grindedal, Eli Marie ^d   Aarset, Harald ^a   Stormorken, Astrid ^e   Engebretsen, Lars F ^c   Jonsrud, Christoffer ^f   Bjørnevoll, Inga ^a   Andresen, Per Arne ^d   Ariansen, Sarah ^d   Lavik, Liss Anne S ^a   Gilde, Bodil ^a   Bowitz Lothe, Inger Marie ^e   Mæhle, Lovise ^d   Møller, Pål ^d  

^a TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^f UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

MISMATCH REPAIR PROTEIN; MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ARTICLE; CLINICAL ASSESSMENT; COLORECTAL CANCER; CONTROLLED STUDY; FAMILY STUDY; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOTE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; NUCLEOTIDE SEQUENCE; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

EID: 77956127299     PISSN: 00222593     EISSN: 14686244     Source Type: Journal    
DOI: 10.1136/jmg.2010.077677     Document Type: Article

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