Efficient production of Fah-null heterozygote pigs by chimeric adeno-associated virus-mediated gene knockout and somatic cell nuclear transfer

Hepatology

Volumn 54, Issue 4, 2011, Pages 1351-1359

  Hickey, Raymond D ^a   Lillegard, Joseph B ^b   Fisher, James E ^b   McKenzie, Travis J ^b   Hofherr, Sean E ^c   Finegold, Milton J ^d   Nyberg, Scott L ^b   Grompe, Markus ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

^c Mayo Clinic College of Medicine   (United States)

^d TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; FAH PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ARTICLE; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; EMBRYO TRANSFER; ENZYME ACTIVITY; FEMALE; FETUS; FETUS LIVER; FIBROBLAST; GENE INACTIVATION; GENE TARGETING; HETEROZYGOTE; HYBRID; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PHENOTYPE; PIGLET; PRIORITY JOURNAL; SEROTYPE; SOMATIC CELL; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, SOUTHERN; CHIMERA; DEPENDOVIRUS; FETUS; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; GENETIC VECTORS; HETEROZYGOTE; HOMOLOGOUS RECOMBINATION; HYDROLASES; MODELS, ANIMAL; NUCLEAR TRANSFER TECHNIQUES; OOCYTES; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SWINE; TYROSINEMIAS;

EID: 81155162423     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24490     Document Type: Article

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