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Volumn 58, Issue 1, 2012, Pages 144-148

The Endocannabinoid System: Role in Energy Regulation

Author keywords

Anandamide; Appetite; Endogenous cannabinoid; Lipogenesis; Obesity; Rimonabant

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABIS; DRONABINOL; ENDOCANNABINOID;

EID: 81155125290     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23367     Document Type: Review
Times cited : (30)

References (84)
  • 2
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni Y, Mechoulam R. Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc 1964;86:1646-1647.
    • (1964) J Am Chem Soc , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 3
    • 27844525479 scopus 로고    scopus 로고
    • Chemical constituents of marijuana: The complex mixture of natural cannabinoids
    • Elsohly MA, Slade D. Chemical constituents of marijuana: The complex mixture of natural cannabinoids. Life Sci 2005;78:539-548.
    • (2005) Life Sci , vol.78 , pp. 539-548
    • Elsohly, M.A.1    Slade, D.2
  • 4
    • 33847363278 scopus 로고    scopus 로고
    • Chemotherapy-induced nausea and vomiting: Clinician and patient perspectives
    • Schwartzberg L. Chemotherapy-induced nausea and vomiting: Clinician and patient perspectives. J Support Oncol 2007;5:5-12.
    • (2007) J Support Oncol , vol.5 , pp. 5-12
    • Schwartzberg, L.1
  • 5
    • 34548255920 scopus 로고    scopus 로고
    • Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: Beyond prevention of acute emesis
    • Slatkin N. Cannabinoids in the treatment of chemotherapy-induced nausea and vomiting: Beyond prevention of acute emesis. J Support Oncol 2007;5:1-9.
    • (2007) J Support Oncol , vol.5 , pp. 1-9
    • Slatkin, N.1
  • 6
    • 41149130137 scopus 로고    scopus 로고
    • Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program
    • Van Gaal L, Pi-Sunyer X, Despres JP, et al. Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: Pooled 1-year data from the Rimonabant in Obesity (RIO) program. Diabetes Care 2008;31:S229-S240.
    • (2008) Diabetes Care , vol.31
    • Van Gaal, L.1    Pi-Sunyer, X.2    Despres, J.P.3
  • 7
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L, Lolait S, Brownstein M, et al. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990;346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.1    Lolait, S.2    Brownstein, M.3
  • 8
    • 81155122829 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids.
    • Munro S, Thomas K, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. 1993.
    • (1993)
    • Munro, S.1    Thomas, K.2    Abu-Shaar, M.3
  • 9
    • 0028987880 scopus 로고
    • Pharmacology of cannabinoid receptors
    • Howlett A. Pharmacology of cannabinoid receptors. Annu Rev Pharmacol Toxicol 1995;35:607-634.
    • (1995) Annu Rev Pharmacol Toxicol , vol.35 , pp. 607-634
    • Howlett, A.1
  • 10
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • Pacher P, Batkai S, Kunos G. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 2006;58:389-462.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Batkai, S.2    Kunos, G.3
  • 11
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee R. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol 2009;156:397-411.
    • (2009) Br J Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.1
  • 12
    • 0033538346 scopus 로고    scopus 로고
    • Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors
    • Pertwee R. Evidence for the presence of CB1 cannabinoid receptors on peripheral neurones and for the existence of neuronal non-CB1 cannabinoid receptors. Life Sci 1999;65:597-605.
    • (1999) Life Sci , vol.65 , pp. 597-605
    • Pertwee, R.1
  • 13
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
    • Herkenham M, Lynn A, Johnson M, et al. Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study. J Neurosci 1991;11:563.
    • (1991) J Neurosci , vol.11 , pp. 563
    • Herkenham, M.1    Lynn, A.2    Johnson, M.3
  • 14
    • 0029012014 scopus 로고
    • Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
    • Mechoulam R, Ben-Shabat S, Hanus L, et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 1995;50:83-90.
    • (1995) Biochem Pharmacol , vol.50 , pp. 83-90
    • Mechoulam, R.1    Ben-Shabat, S.2    Hanus, L.3
  • 15
    • 0028970517 scopus 로고
    • 2-Arachidonoyglycerol: A possible endogenous cannabinoid receptor ligand in brain
    • Sugiura T, Kondo S, Sukagawa A, et al. 2-Arachidonoyglycerol: A possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Commun 1995;215:89-97.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 89-97
    • Sugiura, T.1    Kondo, S.2    Sukagawa, A.3
  • 16
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane W, Hanus L, Breuer A, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992;258:1946.
    • (1992) Science , vol.258 , pp. 1946
    • Devane, W.1    Hanus, L.2    Breuer, A.3
  • 17
    • 44849141696 scopus 로고    scopus 로고
    • Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
    • Ahn K, McKinney MK, Cravatt BF. Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chem Rev 2008;108:1687-1707.
    • (2008) Chem Rev , vol.108 , pp. 1687-1707
    • Ahn, K.1    McKinney, M.K.2    Cravatt, B.F.3
  • 18
    • 81155139454 scopus 로고
    • Formation and inactivation of endogenous cannabinoid anandamide in central neurons.
    • Di Marzo V, Fontana A, Cadas H, et al. Formation and inactivation of endogenous cannabinoid anandamide in central neurons. 1994.
    • (1994)
    • Di Marzo, V.1    Fontana, A.2    Cadas, H.3
  • 19
    • 58249113979 scopus 로고    scopus 로고
    • Endocannabinoid-mediated control of synaptic transmission
    • Kano M, Ohno-Shosaku T, Hashimotodani Y, et al. Endocannabinoid-mediated control of synaptic transmission. Physiol Rev 2009;89:309.
    • (2009) Physiol Rev , vol.89 , pp. 309
    • Kano, M.1    Ohno-Shosaku, T.2    Hashimotodani, Y.3
  • 20
    • 0030870722 scopus 로고    scopus 로고
    • A second endogenous cannabinoid that modulates long-term potentiation
    • Stella N, Schweitzer P, Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature 1997;388:773-778.
    • (1997) Nature , vol.388 , pp. 773-778
    • Stella, N.1    Schweitzer, P.2    Piomelli, D.3
  • 21
    • 76649137560 scopus 로고    scopus 로고
    • Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
    • Gao Y, Vasilyev DV, Goncalves MB, et al. Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J Neurosci 2010;30:2017-2024.
    • (2010) J Neurosci , vol.30 , pp. 2017-2024
    • Gao, Y.1    Vasilyev, D.V.2    Goncalves, M.B.3
  • 22
    • 77249139698 scopus 로고    scopus 로고
    • Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus
    • Min R, Testa-Silva G, Heistek TS, et al. Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus. J Neurosci 2010;30:2710-2715.
    • (2010) J Neurosci , vol.30 , pp. 2710-2715
    • Min, R.1    Testa-Silva, G.2    Heistek, T.S.3
  • 23
    • 37349085419 scopus 로고    scopus 로고
    • The stimulatory effect of phosphatidylethanolamine on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD)
    • Wang J, Okamoto Y, Tsuboi K, et al. The stimulatory effect of phosphatidylethanolamine on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD). Neuropharmacology 2008;54:8-15.
    • (2008) Neuropharmacology , vol.54 , pp. 8-15
    • Wang, J.1    Okamoto, Y.2    Tsuboi, K.3
  • 24
    • 33645935391 scopus 로고    scopus 로고
    • Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
    • Leung D, Saghatelian A, Simon G, et al. Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry 2006;45:4720-4726.
    • (2006) Biochemistry , vol.45 , pp. 4720-4726
    • Leung, D.1    Saghatelian, A.2    Simon, G.3
  • 25
    • 77954819357 scopus 로고    scopus 로고
    • Endocannabinoid biosynthesis and inactivation, from simple to complex
    • Muccioli G. Endocannabinoid biosynthesis and inactivation, from simple to complex. Drug Discov Today 2010.
    • (2010) Drug Discov Today
    • Muccioli, G.1
  • 26
    • 33748743637 scopus 로고    scopus 로고
    • Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway
    • Simon GM, Cravatt BF. Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway. J Biol Chem 2006;281:26465-26472.
    • (2006) J Biol Chem , vol.281 , pp. 26465-26472
    • Simon, G.M.1    Cravatt, B.F.2
  • 27
    • 77954582423 scopus 로고    scopus 로고
    • Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo
    • Simon GM, Cravatt BF. Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo. Mol Biosyst 2010;6:1411-1418.
    • (2010) Mol Biosyst , vol.6 , pp. 1411-1418
    • Simon, G.M.1    Cravatt, B.F.2
  • 28
    • 0030865871 scopus 로고    scopus 로고
    • Functional role of high-affinity anandamide transport, as revealed by selective inhibition
    • Beltramo M, Stella N, Calignano A, et al. Functional role of high-affinity anandamide transport, as revealed by selective inhibition. Science 1997;277:1094-1097.
    • (1997) Science , vol.277 , pp. 1094-1097
    • Beltramo, M.1    Stella, N.2    Calignano, A.3
  • 29
    • 0033545991 scopus 로고    scopus 로고
    • Structural determinants for recognition and translocation by the anandamide transporter
    • Piomelli D, Beltramo M, Glasnapp S, et al. Structural determinants for recognition and translocation by the anandamide transporter. Proc Natl Acad Sci USA 1999;96:5802-5807.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5802-5807
    • Piomelli, D.1    Beltramo, M.2    Glasnapp, S.3
  • 30
    • 0035979244 scopus 로고    scopus 로고
    • Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
    • Cravatt BF, Demarest K, Patricelli MP, et al. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc Natl Acad Sci USA 2001;98:9371-9376.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9371-9376
    • Cravatt, B.F.1    Demarest, K.2    Patricelli, M.P.3
  • 31
    • 0036678094 scopus 로고    scopus 로고
    • Brain monoglyceride lipase participating in endocannabinoid inactivation
    • Dinh TP, Carpenter D, Leslie FM, et al. Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc Natl Acad Sci USA 2002;99:10819-10824.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10819-10824
    • Dinh, T.P.1    Carpenter, D.2    Leslie, F.M.3
  • 32
    • 37149013708 scopus 로고    scopus 로고
    • A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
    • Blankman J, Simon G, Cravatt B. A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol. Chem Biol 2007;14:1347-1356.
    • (2007) Chem Biol , vol.14 , pp. 1347-1356
    • Blankman, J.1    Simon, G.2    Cravatt, B.3
  • 33
    • 77955053537 scopus 로고    scopus 로고
    • The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
    • Marrs W, Blankman J, Horne E, et al. The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors. Nat Neurosci 2010;13:951-957.
    • (2010) Nat Neurosci , vol.13 , pp. 951-957
    • Marrs, W.1    Blankman, J.2    Horne, E.3
  • 34
    • 33745487912 scopus 로고    scopus 로고
    • Endocannabinoid synthesis and degradation, and their regulation in the framework of energy balance
    • Matias I, Di Marzo V. Endocannabinoid synthesis and degradation, and their regulation in the framework of energy balance. J Endocrinol Invest 2006;29:15.
    • (2006) J Endocrinol Invest , vol.29 , pp. 15
    • Matias, I.1    Di Marzo, V.2
  • 35
    • 33645507624 scopus 로고    scopus 로고
    • Endocannabinoids, feeding and suckling-From our perspective
    • Mechoulam R, Berry E, Avraham Y, et al. Endocannabinoids, feeding and suckling-From our perspective. Int J Obes 2006;30:S24-S28.
    • (2006) Int J Obes , vol.30
    • Mechoulam, R.1    Berry, E.2    Avraham, Y.3
  • 36
    • 0014975470 scopus 로고
    • Hunger and appetite after single doses of marihuana, alcohol, and dextroamphetamine
    • Hollister LE. Hunger and appetite after single doses of marihuana, alcohol, and dextroamphetamine. Clin Pharmacol Ther 1971;12:44-49.
    • (1971) Clin Pharmacol Ther , vol.12 , pp. 44-49
    • Hollister, L.E.1
  • 37
    • 0015243053 scopus 로고
    • Effects of marihuana on the solution of anagrams, memory and appetite
    • Abel E. Effects of marihuana on the solution of anagrams, memory and appetite. Nature 1971;231:260-261.
    • (1971) Nature , vol.231 , pp. 260-261
    • Abel, E.1
  • 38
    • 0141975204 scopus 로고    scopus 로고
    • The cannabinoid system: A role in both the homeostatic and hedonic control of eating
    • Harrold J, Williams G. The cannabinoid system: A role in both the homeostatic and hedonic control of eating? Br J Nutr 2007;90:729-734.
    • (2007) Br J Nutr , vol.90 , pp. 729-734
    • Harrold, J.1    Williams, G.2
  • 39
    • 0017064020 scopus 로고
    • Effects of marihuana use on body weight and caloric intake in humans
    • Greenberg I, Kuehnle J, Mendelson J, et al. Effects of marihuana use on body weight and caloric intake in humans. Psychopharmacology 1976;49:79-84.
    • (1976) Psychopharmacology , vol.49 , pp. 79-84
    • Greenberg, I.1    Kuehnle, J.2    Mendelson, J.3
  • 40
    • 0022900093 scopus 로고
    • Behavioral analysis of marijuana effects on food intake in humans
    • Foltin R, Brady J, Fischman M. Behavioral analysis of marijuana effects on food intake in humans. Pharmacol Biochem Behav 1986;25:577-582.
    • (1986) Pharmacol Biochem Behav , vol.25 , pp. 577-582
    • Foltin, R.1    Brady, J.2    Fischman, M.3
  • 41
    • 67649563560 scopus 로고    scopus 로고
    • The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation
    • Di Marzo V, Ligresti A, Cristino L. The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation. Int J Obes 2009;33:S18-S24.
    • (2009) Int J Obes , vol.33
    • Di Marzo, V.1    Ligresti, A.2    Cristino, L.3
  • 42
    • 50349086035 scopus 로고    scopus 로고
    • Therapeutic use of Cannabis sativa on chemotherapy-induced nausea and vomiting among cancer patients: Systematic review and meta-analysis
    • Machado R, Stéfano S, De Cássia H, et al. Therapeutic use of Cannabis sativa on chemotherapy-induced nausea and vomiting among cancer patients: Systematic review and meta-analysis. Eur J Cancer Care 2008;17:431.
    • (2008) Eur J Cancer Care , vol.17 , pp. 431
    • Machado, R.1    Stéfano, S.2    De Cássia, H.3
  • 44
    • 0030886734 scopus 로고    scopus 로고
    • Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease
    • Volicer L, Stelly M, Morris J, et al. Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease. Int J Geriatr Psychiatry 1997;12:913-919.
    • (1997) Int J Geriatr Psychiatry , vol.12 , pp. 913-919
    • Volicer, L.1    Stelly, M.2    Morris, J.3
  • 46
    • 0017187470 scopus 로고
    • Comparative effects of various naturally occurring cannabinoids on food, sucrose and water consumption by rats
    • Sofia R, Knobloch L. Comparative effects of various naturally occurring cannabinoids on food, sucrose and water consumption by rats. Pharmacol Biochem Behav 1976;4:591-599.
    • (1976) Pharmacol Biochem Behav , vol.4 , pp. 591-599
    • Sofia, R.1    Knobloch, L.2
  • 47
    • 0002539423 scopus 로고
    • Increased and decreased eating following THC administration
    • Glick S, Milloy S. Increased and decreased eating following THC administration. Psychon Sci 1972;29:6.
    • (1972) Psychon Sci , vol.29 , pp. 6
    • Glick, S.1    Milloy, S.2
  • 48
    • 0017645859 scopus 로고
    • Kinetic studies of food intake and sucrose solution preference by rats treated with low doses of [Delta] 9-tetrahydrocannabinol1
    • Brown J, Kassouny M, Cross J. Kinetic studies of food intake and sucrose solution preference by rats treated with low doses of [Delta] 9-tetrahydrocannabinol1. Behavioral biology 1977;20:104-110.
    • (1977) Behavioral biology , vol.20 , pp. 104-110
    • Brown, J.1    Kassouny, M.2    Cross, J.3
  • 49
    • 0018223768 scopus 로고
    • Food and water intake, meal patterns and activity of obese and lean Zucker rats following chronic and acute treatment with delta9-tetrahydrocannabinol
    • Drewnowski A, Grinker J. Food and water intake, meal patterns and activity of obese and lean Zucker rats following chronic and acute treatment with delta9-tetrahydrocannabinol. Pharmacol biochem behav 1978;9:619.
    • (1978) Pharmacol biochem behav , vol.9 , pp. 619
    • Drewnowski, A.1    Grinker, J.2
  • 50
    • 21244434879 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor-mediated modulation of food intake in mice
    • Wiley JL, Burston JJ, Leggett DC, et al. CB1 cannabinoid receptor-mediated modulation of food intake in mice. Br J Pharmacol 2005;145:293-300.
    • (2005) Br J Pharmacol , vol.145 , pp. 293-300
    • Wiley, J.L.1    Burston, J.J.2    Leggett, D.C.3
  • 52
    • 0019976180 scopus 로고
    • Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens
    • Vaupel D, Morton E. Anorexia and hyperphagia produced by five pharmacologic classes of hallucinogens. Pharmacol Biochem Behav 1982;17:539-545.
    • (1982) Pharmacol Biochem Behav , vol.17 , pp. 539-545
    • Vaupel, D.1    Morton, E.2
  • 53
    • 0034737597 scopus 로고    scopus 로고
    • Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice
    • Hao S, Avraham Y, Mechoulam R, et al. Low dose anandamide affects food intake, cognitive function, neurotransmitter and corticosterone levels in diet-restricted mice. Eur J Pharmacol 2000;392:147-156.
    • (2000) Eur J Pharmacol , vol.392 , pp. 147-156
    • Hao, S.1    Avraham, Y.2    Mechoulam, R.3
  • 54
    • 0036607403 scopus 로고    scopus 로고
    • Observational analysis of feeding induced by Delta9-THC and anandamide
    • Williams CM, Kirkham TC. Observational analysis of feeding induced by Delta9-THC and anandamide. Physiol Behav 2002;76:241-250.
    • (2002) Physiol Behav , vol.76 , pp. 241-250
    • Williams, C.M.1    Kirkham, T.C.2
  • 55
    • 0036849961 scopus 로고    scopus 로고
    • A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding
    • Gomez R, Navarro M, Ferrer B, et al. A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding. J Neurosci 2002;22:9612.
    • (2002) J Neurosci , vol.22 , pp. 9612
    • Gomez, R.1    Navarro, M.2    Ferrer, B.3
  • 56
    • 0032936642 scopus 로고    scopus 로고
    • Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
    • Williams C, Kirkham T. Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors. Psychopharmacology 1999;143:315-317.
    • (1999) Psychopharmacology , vol.143 , pp. 315-317
    • Williams, C.1    Kirkham, T.2
  • 57
    • 0030738512 scopus 로고    scopus 로고
    • Selective inhibition of sucrose and ethanol intake by SR141716, an antagonist of central cannabinoid (CB1) receptors
    • Arnone M, Maruani J, Chaperon F, et al. Selective inhibition of sucrose and ethanol intake by SR141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 1997;132:104-106.
    • (1997) Psychopharmacology (Berl) , vol.132 , pp. 104-106
    • Arnone, M.1    Maruani, J.2    Chaperon, F.3
  • 58
    • 0026031930 scopus 로고
    • Facilitory effect of 9-tetrahydrocannabinol on hypothalamically induced feeding
    • Trojniar W, Wise R. Facilitory effect of 9-tetrahydrocannabinol on hypothalamically induced feeding. Psychopharmacology 1991;103:172-176.
    • (1991) Psychopharmacology , vol.103 , pp. 172-176
    • Trojniar, W.1    Wise, R.2
  • 59
    • 0035185205 scopus 로고    scopus 로고
    • Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
    • Jamshidi N, Taylor D. Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. Br J Pharmacol 2001;134:1151-1154.
    • (2001) Br J Pharmacol , vol.134 , pp. 1151-1154
    • Jamshidi, N.1    Taylor, D.2
  • 60
    • 0035848818 scopus 로고    scopus 로고
    • Leptin-regulated endocannabinoids are involved in maintaining food intake
    • Di Marzo V, Goparaju SK, Wang L, et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001;410:822-825.
    • (2001) Nature , vol.410 , pp. 822-825
    • Di Marzo, V.1    Goparaju, S.K.2    Wang, L.3
  • 61
    • 0035984946 scopus 로고    scopus 로고
    • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
    • Kirkham T, Williams C, Fezza F, et al. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 2002;136:550-557.
    • (2002) Br J Pharmacol , vol.136 , pp. 550-557
    • Kirkham, T.1    Williams, C.2    Fezza, F.3
  • 62
    • 70349681070 scopus 로고    scopus 로고
    • Cannabinoid in the nucleus accumbens enhances the intake of palatable solution
    • Shinohara Y, Inui T, Yamamoto T, et al. Cannabinoid in the nucleus accumbens enhances the intake of palatable solution. Neuroreport 2009;20:1382.
    • (2009) Neuroreport , vol.20 , pp. 1382
    • Shinohara, Y.1    Inui, T.2    Yamamoto, T.3
  • 63
    • 81155122830 scopus 로고    scopus 로고
    • The cannabinoid receptor antagonist SR141716 fails to suppress sucrose sham feeding
    • Kirkham T, Williams C. The cannabinoid receptor antagonist SR141716 fails to suppress sucrose sham feeding. J Psychopharmacol 1998:12.
    • J Psychopharmacol , vol.1998 , pp. 12
    • Kirkham, T.1    Williams, C.2
  • 64
    • 55749101589 scopus 로고    scopus 로고
    • Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats
    • DiPatrizio N, Simansky K. Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. J Neurosci 2008;28:9702.
    • (2008) J Neurosci , vol.28 , pp. 9702
    • DiPatrizio, N.1    Simansky, K.2
  • 65
  • 66
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • Cota D, Marsicano G, Tschop M, et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003;112:423-431.
    • (2003) J Clin Invest , vol.112 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschop, M.3
  • 67
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D, DePetrillo M, Pacher P, et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 2005;115:1298-1305.
    • (2005) J Clin Invest , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    DePetrillo, M.2    Pacher, P.3
  • 68
    • 0031902759 scopus 로고    scopus 로고
    • SR141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset
    • Simiand J, Keane M, Keane P, et al. SR141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset. Behav Pharmacol 1998;9:179.
    • (1998) Behav Pharmacol , vol.9 , pp. 179
    • Simiand, J.1    Keane, M.2    Keane, P.3
  • 69
    • 0032541111 scopus 로고    scopus 로고
    • Appetite suppression and weight loss after the cannabinoid antagonist SR141716
    • Colombo G, Agabio R, Diaz G, et al. Appetite suppression and weight loss after the cannabinoid antagonist SR141716. Life Sci 1998;63:PL113-117.
    • (1998) Life Sci , vol.63
    • Colombo, G.1    Agabio, R.2    Diaz, G.3
  • 70
    • 0034535520 scopus 로고    scopus 로고
    • Effects of SR141716A, a central cannabinoid receptor antagonist, on food-maintained responding
    • Freedland C, Poston J, Porrino L. Effects of SR141716A, a central cannabinoid receptor antagonist, on food-maintained responding. Pharmacol Biochem Behav 2000;67:265-270.
    • (2000) Pharmacol Biochem Behav , vol.67 , pp. 265-270
    • Freedland, C.1    Poston, J.2    Porrino, L.3
  • 71
    • 26044473133 scopus 로고    scopus 로고
    • The role of CB1 receptors in sweet versus fat reinforcement: Effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940)
    • Ward S, Dykstra L. The role of CB1 receptors in sweet versus fat reinforcement: Effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940). Behav Pharmacol 2005;16:381.
    • (2005) Behav Pharmacol , vol.16 , pp. 381
    • Ward, S.1    Dykstra, L.2
  • 72
    • 17644367480 scopus 로고    scopus 로고
    • The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consummatory responses for food
    • Thornton-Jones Z, Vickers S, Clifton P. The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consummatory responses for food. Psychopharmacology 2005;179:452-460.
    • (2005) Psychopharmacology , vol.179 , pp. 452-460
    • Thornton-Jones, Z.1    Vickers, S.2    Clifton, P.3
  • 73
    • 0042667093 scopus 로고    scopus 로고
    • The cannabinoid receptor antagonist SR141716 attenuates overfeeding induced by systemic or intracranial morphine
    • Verty A, Singh M, McGregor I, et al. The cannabinoid receptor antagonist SR141716 attenuates overfeeding induced by systemic or intracranial morphine. Psychopharmacology 2003;168:314-323.
    • (2003) Psychopharmacology , vol.168 , pp. 314-323
    • Verty, A.1    Singh, M.2    McGregor, I.3
  • 74
    • 0037053104 scopus 로고    scopus 로고
    • Effect of opioid and cannabinoid receptor antagonism on orphanin FQ-induced hyperphagia in rats
    • Pietras T, Rowland N. Effect of opioid and cannabinoid receptor antagonism on orphanin FQ-induced hyperphagia in rats. Eur J Pharmacol 2002;442:237-239.
    • (2002) Eur J Pharmacol , vol.442 , pp. 237-239
    • Pietras, T.1    Rowland, N.2
  • 75
    • 0035142565 scopus 로고    scopus 로고
    • Synergistic effects of opioid and cannabinoid antagonists on food intake
    • Kirkham T, Williams C. Synergistic effects of opioid and cannabinoid antagonists on food intake. Psychopharmacologia 2001;153:267-270.
    • (2001) Psychopharmacologia , vol.153 , pp. 267-270
    • Kirkham, T.1    Williams, C.2
  • 76
    • 3042640680 scopus 로고    scopus 로고
    • Evidence for an interaction between CB1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake
    • Verty A, McFarlane J, McGregor I, et al. Evidence for an interaction between CB1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake. Endocrinology 2004;145:3224.
    • (2004) Endocrinology , vol.145 , pp. 3224
    • Verty, A.1    McFarlane, J.2    McGregor, I.3
  • 77
    • 4544280481 scopus 로고    scopus 로고
    • Evidence for an interaction between CB1 cannabinoid and oxytocin receptors in food and water intake
    • Verty A, McFarlane J, McGregor I, et al. Evidence for an interaction between CB1 cannabinoid and oxytocin receptors in food and water intake. Neuropharmacology 2004;47:593-5603.
    • (2004) Neuropharmacology , vol.47 , pp. 593-5603
    • Verty, A.1    McFarlane, J.2    McGregor, I.3
  • 78
    • 33746110406 scopus 로고    scopus 로고
    • Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole-LH 21
    • Pavon F, Bilbao A, Hernández-Folgado L, et al. Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2, 4-dichlorophenyl)-3-hexyl-1H-1, 2, 4-triazole-LH 21. Neuropharmacology 2006;51:358-366.
    • (2006) Neuropharmacology , vol.51 , pp. 358-366
    • Pavon, F.1    Bilbao, A.2    Hernández-Folgado, L.3
  • 80
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
    • Pi-Sunyer F, Aronne L, Heshmati H, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial. JAMA 2006;295:761.
    • (2006) JAMA , vol.295 , pp. 761
    • Pi-Sunyer, F.1    Aronne, L.2    Heshmati, H.3
  • 81
    • 78649954020 scopus 로고    scopus 로고
    • A Randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet
    • Wadden TA, Fujioka K, Toubro S, et al. A Randomized trial of lifestyle modification and taranabant for maintaining weight loss achieved with a low-calorie diet. Obesity (Silver Spring) 2010.
    • (2010) Obesity (Silver Spring)
    • Wadden, T.A.1    Fujioka, K.2    Toubro, S.3
  • 82
    • 75949122654 scopus 로고    scopus 로고
    • Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant
    • Martin-Garcia E, Burokas A, Martin M, et al. Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant. J Neurochem 2010;112:1338-1351.
    • (2010) J Neurochem , vol.112 , pp. 1338-1351
    • Martin-Garcia, E.1    Burokas, A.2    Martin, M.3
  • 83
    • 77957749920 scopus 로고    scopus 로고
    • The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior
    • Randall PA, Vemuri VK, Segovia KN, et al. The novel cannabinoid CB1 antagonist AM6545 suppresses food intake and food-reinforced behavior. Pharmacol Biochem Behav 2010.
    • (2010) Pharmacol Biochem Behav
    • Randall, P.A.1    Vemuri, V.K.2    Segovia, K.N.3
  • 84
    • 77955286305 scopus 로고    scopus 로고
    • Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity
    • Tam J, Vemuri VK, Liu J, et al. Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity. J Clin Invest 2010;120:2953-2966.
    • (2010) J Clin Invest , vol.120 , pp. 2953-2966
    • Tam, J.1    Vemuri, V.K.2    Liu, J.3


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