Costunolide induces apoptosis in platinum-resistant human ovarian cancer cells by generating reactive oxygen species

Gynecologic Oncology

Volumn 123, Issue 3, 2011, Pages 588-596

  Yang, Yeong In ^a   Kim, Ji Hyun ^a   Lee, Kyung Tae ^a   Choi, Jung Hye ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Apoptosis; Costunolide; Keywords; Ovarian cancer; Platinum resistance; ROS

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CASPASE 9; CISPLATIN; COSTUNOLIDE; LIPOCORTIN 5; PLATINUM; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SESQUITERPENE LACTONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL CYCLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CASPASES; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; ENZYME ACTIVATION; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; ORGANOPLATINUM COMPOUNDS; OVARIAN NEOPLASMS; REACTIVE OXYGEN SPECIES; SESQUITERPENES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 81155123109     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.08.031     Document Type: Article

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