메뉴 건너뛰기




Volumn 6, Issue 11, 2011, Pages 1373-1377

Maintenance of DNA methylation: Dnmt3b joins the dance

Author keywords

DNA methylation; Dnmt1; Dnmt3b; Gene expression; Germ line genes; Silencing

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; TRANSCRIPTION FACTOR E2F6;

EID: 81055136654     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.6.11.17978     Document Type: Article
Times cited : (54)

References (50)
  • 1
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar H. DNA methylation and gene activity. Cell 1988; 53:3-4.
    • (1988) Cell , vol.53 , pp. 3-4
    • Cedar, H.1
  • 2
    • 64349091471 scopus 로고    scopus 로고
    • Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
    • Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 2009; 27:361-8.
    • (2009) Nat Biotechnol , vol.27 , pp. 361-368
    • Ball, M.P.1    Li, J.B.2    Gao, Y.3    Lee, J.H.4    Leproust, E.M.5    Park, I.H.6
  • 3
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird A. DNA methylation patterns and epigenetic memory. Genes Dev 2002; 16:6-21.
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 6
    • 34047116826 scopus 로고    scopus 로고
    • Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
    • Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007; 39:457-66.
    • (2007) Nat Genet , vol.39 , pp. 457-466
    • Weber, M.1    Hellmann, I.2    Stadler, M.B.3    Ramos, L.4    Paabo, S.5    Rebhan, M.6
  • 7
    • 0036000250 scopus 로고    scopus 로고
    • A human CpG island randomly inserted into a plant genome is protected from methylation
    • Meza TJ, Enerly E, Boru B, Larsen F, Mandal A, Aalen RB, et al. A human CpG island randomly inserted into a plant genome is protected from methylation. Transgenic Res 2002; 11:133-42.
    • (2002) Transgenic Res , vol.11 , pp. 133-142
    • Meza, T.J.1    Enerly, E.2    Boru, B.3    Larsen, F.4    Mandal, A.5    Aalen, R.B.6
  • 8
    • 0022000776 scopus 로고
    • A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA
    • Bird A, Taggart M, Frommer M, Miller OJ, Macleod D. A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA. Cell 1985; 40:91-9.
    • (1985) Cell , vol.40 , pp. 91-99
    • Bird, A.1    Taggart, M.2    Frommer, M.3    Miller, O.J.4    Macleod, D.5
  • 9
    • 52949138674 scopus 로고    scopus 로고
    • On the nature of human housekeeping genes
    • Zhu J, He F, Hu S, Yu J. On the nature of human housekeeping genes. Trends Genet 2008; 24:481-4.
    • (2008) Trends Genet , vol.24 , pp. 481-484
    • Zhu, J.1    He, F.2    Hu, S.3    Yu, J.4
  • 10
    • 0026742792 scopus 로고
    • CpG islands as gene markers in the human genome
    • Larsen F, Gundersen G, Lopez R, Prydz H. CpG islands as gene markers in the human genome. Genomics 1992; 13:1095-107.
    • (1992) Genomics , vol.13 , pp. 1095-1107
    • Larsen, F.1    Gundersen, G.2    Lopez, R.3    Prydz, H.4
  • 11
    • 66149108044 scopus 로고    scopus 로고
    • CpG islands: Starting blocks for replication and transcription
    • Prioleau MN. CpG islands: starting blocks for replication and transcription. PLoS Genet 2009; 5:1000454.
    • (2009) PLoS Genet , vol.5 , pp. 1000454
    • Prioleau, M.N.1
  • 12
    • 2642647114 scopus 로고    scopus 로고
    • Initiation of DNA replication at CpG islands in mammalian chromosomes
    • Delgado S, Gomez M, Bird A, Antequera F. Initiation of DNA replication at CpG islands in mammalian chromosomes. EMBO J 1998; 17:2426-35.
    • (1998) EMBO J , vol.17 , pp. 2426-2435
    • Delgado, S.1    Gomez, M.2    Bird, A.3    Antequera, F.4
  • 13
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W, Dean W, Walter J. Epigenetic reprogramming in mammalian development. Science 2001; 293:1089-93.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 14
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat Rev Genet 2002; 3:662-73.
    • (2002) Nat Rev Genet , vol.3 , pp. 662-673
    • Li, E.1
  • 15
  • 16
    • 35948981875 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
    • Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, et al. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet 2007; 3:2023-36.
    • (2007) PLoS Genet , vol.3 , pp. 2023-2036
    • Shen, L.1    Kondo, Y.2    Guo, Y.3    Zhang, J.4    Zhang, L.5    Ahmed, S.6
  • 17
    • 33749396836 scopus 로고    scopus 로고
    • DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
    • Maatouk DM, Kellam LD, Mann MR, Lei H, Li E, Bartolomei MS, et al. DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development 2006; 133:3411-8.
    • (2006) Development , vol.133 , pp. 3411-3418
    • Maatouk, D.M.1    Kellam, L.D.2    Mann, M.R.3    Lei, H.4    Li, E.5    Bartolomei, M.S.6
  • 18
    • 38949212693 scopus 로고    scopus 로고
    • A novel CpG island set identifies tissuespecific methylation at developmental gene loci
    • Illingworth R, Kerr A, Desousa D, Jorgensen H, Ellis P, Stalker J, et al. A novel CpG island set identifies tissuespecific methylation at developmental gene loci. PLoS Biol 2008; 6:22.
    • (2008) PLoS Biol , vol.6 , pp. 22
    • Illingworth, R.1    Kerr, A.2    Desousa, D.3    Jorgensen, H.4    Ellis, P.5    Stalker, J.6
  • 19
    • 78649459828 scopus 로고    scopus 로고
    • Targets and dynamics of promoter DNA methylation during early mouse development
    • Borgel J, Guibert S, Li Y, Chiba H, Schubeler D, Sasaki H, et al. Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet 2010; 42:1093-100.
    • (2010) Nat Genet , vol.42 , pp. 1093-1100
    • Borgel, J.1    Guibert, S.2    Li, Y.3    Chiba, H.4    Schubeler, D.5    Sasaki, H.6
  • 20
    • 77952695371 scopus 로고    scopus 로고
    • Dnmt3b recruitment through E2F6 transcriptional repressor mediates germline gene silencing in murine somatic tissues
    • Velasco G, Hube F, Rollin J, Neuillet D, Philippe C, Bouzinba-Segard H, et al. Dnmt3b recruitment through E2F6 transcriptional repressor mediates germline gene silencing in murine somatic tissues. Proc Natl Acad Sci USA 2010; 107:9281-6.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9281-9286
    • Velasco, G.1    Hube, F.2    Rollin, J.3    Neuillet, D.4    Philippe, C.5    Bouzinba-Segard, H.6
  • 21
    • 0032694084 scopus 로고    scopus 로고
    • DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter
    • De Smet C, Lurquin C, Lethe B, Martelange V, Boon T. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Mol Cell Biol 1999; 19:7327-35.
    • (1999) Mol Cell Biol , vol.19 , pp. 7327-7335
    • de Smet, C.1    Lurquin, C.2    Lethe, B.3    Martelange, V.4    Boon, T.5
  • 22
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999; 99:247-57.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 23
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992; 69:915-26.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 24
    • 0034305821 scopus 로고    scopus 로고
    • DNA methylation in health and disease
    • Robertson KD, Wolffe AP. DNA methylation in health and disease. Nat Rev Genet 2000; 1:11-9.
    • (2000) Nat Rev Genet , vol.1 , pp. 11-19
    • Robertson, K.D.1    Wolffe, A.P.2
  • 25
    • 78149478781 scopus 로고    scopus 로고
    • Aberrant epigenetic landscape in cancer: How cellular identity goes awry
    • Berdasco M, Esteller M. Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev Cell 2010; 19:698-711.
    • (2010) Dev Cell , vol.19 , pp. 698-711
    • Berdasco, M.1    Esteller, M.2
  • 26
    • 0034069652 scopus 로고    scopus 로고
    • Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
    • Gibbons RJ, McDowell TL, Raman S, O'Rourke DM, Garrick D, Ayyub H, et al. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat Genet 2000; 24:368-71.
    • (2000) Nat Genet , vol.24 , pp. 368-371
    • Gibbons, R.J.1    McDowell, T.L.2    Raman, S.3    O'Rourke, D.M.4    Garrick, D.5    Ayyub, H.6
  • 27
    • 42649130058 scopus 로고    scopus 로고
    • ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies and gene dysregulation
    • Ehrlich M, Sanchez C, Shao C, Nishiyama R, Kehrl J, Kuick R, et al. ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies and gene dysregulation. Autoimmunity 2008; 41:253-71.
    • (2008) Autoimmunity , vol.41 , pp. 253-271
    • Ehrlich, M.1    Sanchez, C.2    Shao, C.3    Nishiyama, R.4    Kehrl, J.5    Kuick, R.6
  • 28
    • 0024213022 scopus 로고
    • Cloning of a mammalian DNA methyltransferase
    • Bestor TH. Cloning of a mammalian DNA methyltransferase. Gene 1988; 74:9-12.
    • (1988) Gene , vol.74 , pp. 9-12
    • Bestor, T.H.1
  • 29
    • 0032722062 scopus 로고    scopus 로고
    • Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification and comparison of de novo and maintenance methylation
    • Pradhan S, Bacolla A, Wells RD, Roberts RJ. Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification and comparison of de novo and maintenance methylation. J Biol Chem 1999; 274:33002-10.
    • (1999) J Biol Chem , vol.274 , pp. 33002-33010
    • Pradhan, S.1    Bacolla, A.2    Wells, R.D.3    Roberts, R.J.4
  • 30
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang LS, Ian HI, Koh TW, Ng HH, Xu G, Li BF. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 1997; 277:1996-2000.
    • (1997) Science , vol.277 , pp. 1996-2000
    • Chuang, L.S.1    Ian, H.I.2    Koh, T.W.3    Ng, H.H.4    Xu, G.5    Li, B.F.6
  • 32
    • 36849072573 scopus 로고    scopus 로고
    • The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
    • Sharif J, Muto M, Takebayashi S, Suetake I, Iwamatsu A, Endo TA, et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 2007; 450:908-12.
    • (2007) Nature , vol.450 , pp. 908-912
    • Sharif, J.1    Muto, M.2    Takebayashi, S.3    Suetake, I.4    Iwamatsu, A.5    Endo, T.A.6
  • 33
    • 79952836260 scopus 로고    scopus 로고
    • Dnmt1/ Transcription factor interactions: An alternative mechanism of DNA methylation inheritance
    • Hervouet E, Vallette FM, Cartron PF. Dnmt1/ Transcription factor interactions: an alternative mechanism of DNA methylation inheritance. Genes Cancer 2010; 1:434-43.
    • (2010) Genes Cancer , vol.1 , pp. 434-443
    • Hervouet, E.1    Vallette, F.M.2    Cartron, P.F.3
  • 34
    • 33847348016 scopus 로고    scopus 로고
    • DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
    • Spada F, Haemmer A, Kuch D, Rothbauer U, Schermelleh L, Kremmer E, et al. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J Cell Biol 2007; 176:565-71.
    • (2007) J Cell Biol , vol.176 , pp. 565-571
    • Spada, F.1    Haemmer, A.2    Kuch, D.3    Rothbauer, U.4    Schermelleh, L.5    Kremmer, E.6
  • 36
    • 0036135014 scopus 로고    scopus 로고
    • Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
    • Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, et al. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol 2002; 22:480-91.
    • (2002) Mol Cell Biol , vol.22 , pp. 480-491
    • Liang, G.1    Chan, M.F.2    Tomigahara, Y.3    Tsai, Y.C.4    Gonzales, F.A.5    Li, E.6
  • 37
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 1998; 19:219-20.
    • (1998) Nat Genet , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 38
    • 0037023761 scopus 로고    scopus 로고
    • Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a
    • Yokochi T, Robertson KD. Preferential methylation of unmethylated DNA by Mammalian de novo DNA methyltransferase Dnmt3a. J Biol Chem 2002; 277:11735-45.
    • (2002) J Biol Chem , vol.277 , pp. 11735-11745
    • Yokochi, T.1    Robertson, K.D.2
  • 39
    • 9144228185 scopus 로고    scopus 로고
    • Hairpin-bisulfite PCR: Assessing epigenetic methylation patterns on complementary strands of individual DNA molecules
    • Laird CD, Pleasant ND, Clark AD, Sneeden JL, Hassan KM, Manley NC, et al. Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules. Proc Natl Acad Sci USA 2004; 101:204-9.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 204-209
    • Laird, C.D.1    Pleasant, N.D.2    Clark, A.D.3    Sneeden, J.L.4    Hassan, K.M.5    Manley, N.C.6
  • 40
    • 0025119812 scopus 로고
    • Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: Methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability
    • Pfeifer GP, Steigerwald SD, Hansen RS, Gartler SM, Riggs AD. Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc Natl Acad Sci USA 1990; 87:8252-6.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8252-8256
    • Pfeifer, G.P.1    Steigerwald, S.D.2    Hansen, R.S.3    Gartler, S.M.4    Riggs, A.D.5
  • 41
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of enomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen T, Ueda Y, Dodge JE, Wang Z, Li E. Establishment and maintenance of enomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 2003; 23:5594-605.
    • (2003) Mol Cell Biol , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 42
    • 70350046301 scopus 로고    scopus 로고
    • Rethinking how DNA methylation patterns are maintained
    • Jones PA, Liang G. Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 2009; 10:805-11.
    • (2009) Nat Rev Genet , vol.10 , pp. 805-811
    • Jones, P.A.1    Liang, G.2
  • 43
    • 70349322609 scopus 로고    scopus 로고
    • Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
    • Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, et al. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol 2009; 29:5366-76.
    • (2009) Mol Cell Biol , vol.29 , pp. 5366-5376
    • Jeong, S.1    Liang, G.2    Sharma, S.3    Lin, J.C.4    Choi, S.H.5    Han, H.6
  • 44
    • 79952258043 scopus 로고    scopus 로고
    • Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance
    • Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G. Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet 2011; 7:1001286.
    • (2011) PLoS Genet , vol.7 , pp. 1001286
    • Sharma, S.1    de Carvalho, D.D.2    Jeong, S.3    Jones, P.A.4    Liang, G.5
  • 46
    • 33745270104 scopus 로고    scopus 로고
    • Maintenance of selfrenewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
    • Tsumura A, Hayakawa T, Kumaki Y, Takebayashi S, Sakaue M, Matsuoka C, et al. Maintenance of selfrenewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 2006; 11:805-14.
    • (2006) Genes Cells , vol.11 , pp. 805-814
    • Tsumura, A.1    Hayakawa, T.2    Kumaki, Y.3    Takebayashi, S.4    Sakaue, M.5    Matsuoka, C.6
  • 47
    • 72449197125 scopus 로고    scopus 로고
    • A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding
    • Gopalakrishnan S, Van Emburgh BO, Shan J, Su Z, Fields CR, Vieweg J, et al. A novel DNMT3B splice variant expressed in tumor and pluripotent cells modulates genomic DNA methylation patterns and displays altered DNA binding. Mol Cancer Res 2009; 7:1622-34.
    • (2009) Mol Cancer Res , vol.7 , pp. 1622-1634
    • Gopalakrishnan, S.1    van Emburgh, B.O.2    Shan, J.3    Su, Z.4    Fields, C.R.5    Vieweg, J.6
  • 49
    • 0037162542 scopus 로고    scopus 로고
    • Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
    • Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hirohashi S. Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis. Proc Natl Acad Sci USA 2002; 99:10060-5.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10060-10065
    • Saito, Y.1    Kanai, Y.2    Sakamoto, M.3    Saito, H.4    Ishii, H.5    Hirohashi, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.