Organic anion and cation transporters are possibly involved in renal excretion of entecavir in rats

Life Sciences

Volumn 89, Issue 1-2, 2011, Pages 1-6

  Yanxiao, Chen ^a   Ruijuan, Xu ^a   Jin, Yang ^a   Lei, Chen ^a   Qian, Wang ^a   Xuefen, Yin ^a   Hong, Tang ^a   Xueying, Zhang ^a   Davey, Andrew K ^b   Jiping, Wang ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

Entecavir; MRP2; Organic anion and cation transporters; P glycoprotein; Renal excretion

Indexed keywords

BROMSULFOPHTHALEIN; CIMETIDINE; ENTECAVIR; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; ORGANIC CATION TRANSPORTER; PROBENECID; VERAPAMIL;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG STRUCTURE; MALE; NONHUMAN; RAT; STEADY STATE; URINARY EXCRETION;

ANALYSIS OF VARIANCE; ANIMALS; AREA UNDER CURVE; ATP-BINDING CASSETTE TRANSPORTERS; CHROMATOGRAPHY, LIQUID; CIMETIDINE; GUANINE; HALF-LIFE; ION PUMPS; KIDNEY; MALE; MASS SPECTROMETRY; METABOLIC CLEARANCE RATE; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; PROBENECID; RATS; RATS, SPRAGUE-DAWLEY; SULFOBROMOPHTHALEIN; VERAPAMIL;

RATTUS;

EID: 80955180092     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.03.018     Document Type: Article

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