Peripheral blood immune response elicited by beta-lactoglobulin in childhood cow's milk allergy

Pediatric Research

Volumn 70, Issue 6, 2011, Pages 549-554

  Vocca, Immacolata ^a   Canani, Roberto Berni ^b   Camarca, Alessandra ^a   Ruotolo, Serena ^b   Nocerino, Rita ^b   Radano, Giorgia ^a   Del Mastro, Andrea ^b   Troncone, Riccardo ^b   Gianfrani, Carmen ^a  

^a CNR   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTOGLOBULIN; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4;

ARTICLE; BLOOD ANALYSIS; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; INFANT; MALE; MILK ALLERGY; MONONUCLEAR CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; TH1 CELL; TH2 CELL;

AGE FACTORS; ANIMALS; CASE-CONTROL STUDIES; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INFANT; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-4; LACTOGLOBULINS; LEUKOCYTES, MONONUCLEAR; MALE; MILK; MILK HYPERSENSITIVITY; STATISTICS, NONPARAMETRIC; TH2 CELLS;

EID: 80855156784     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e318232739c     Document Type: Article

References (31)

1. Sicherer SH, Sampson HA 2009 Food allergy: recent advances in pathophysiology and treatment. Annu Rev Med 60:261-277
2. Lee LA, Burks W 2006 Food allergies: prevalence, molecular characterization, and treatment/prevention strategies. Annu Rev Nutr 26:539-565
3. Ruiter B, Trégoat V, M'rabet L, Garssen J, Bruijnzeel-Koomen CA, Knol EF, Hoffen E 2006 Characterization of T cell epitopes in alphas1-casein in cow's milk allergic, atopic and non-atopic children. Clin Exp Allergy 36:303-310 (Pubitemid 43344711)
4. Picariello G, Ferranti P, Fierro O, Mamone G, Caira S, Di Luccia A, Monica S, Addeo F 2010 Peptides surviving the simulated gastrointestinal digestion of milk proteins: biological and toxicological implications. J Chromatogr B Analyt Technol Biomed Life Sci 878:295-308
5. Tiemessen MM, Van Ieperen-Van Dijk AG, Bruijnzeel-Koomen CA, Garssen J, Knol EF, Van Hoffen E 2004 Cow's milk-specific T-cell reactivity of children with and without persistent cow's milk allergy: key role for IL-10. J Allergy Clin Immunol 113:932-939 (Pubitemid 38608604)
6. Schade RP, Van Ieperen-Van Dijk AG, Van Reijsen FC, Versluis C, Kimpen JL, Knol EF, Bruijnzeel-Koomen CA, Van Hoffen E 2000 Differences in antigenspecific T-cell responses between infants with atopic dermatitis with and without cow's milk allergy: relevance of TH2 cytokines. J Allergy Clin Immunol 106:1155-1162 (Pubitemid 32006271)
7. Schade RP, Van Ieperen-Van Dijk AG, Versluis C, Van Reijsen FC, Kimpen JL, Bruijnzeel-Koomen CA, Knol EF, Van Hoffen E 2002 Cell-surface expression of CD25, CD26, and CD30 by allergen-specific T cells is intrinsically different in cow's milk allergy. J Allergy Clin Immunol 109:357-362 (Pubitemid 34158306)
8. Tiemessen MM, Kunzmann S, Schmidt-Weber CB, Garssen J, Bruijnzeel-Koomen CA, Knol EF, van Hoffen E 2003 Transforming growth factor-beta inhibits human antigen-specific CD4+T cell proliferation without modulating the cytokine response. Int Immunol 15:1495-1504 (Pubitemid 37536750)
9. Ruiter B, Rozemuller EH, van Dijk AJ, Garssen J, Bruijnzeel-Koomen CA, Tilanus MG, Knol EF, van Hoffen E 2007 Role of human leucocyte antigen DQ in the presentation of T cell epitopes in the major cow's milk allergen alphas1-casein. Int Arch Allergy Immunol 143:119-126 (Pubitemid 46742348)
10. Kondo M, Kaneko H, Fukao T, Suzuki K, Sakaguchi H, Shinoda S, Kato Z, Matsui E, Teramoto T, Nakano T, Kondo N 2008 The response of bovine betalactoglobulin-specific T-cell clones to single amino acid substitution of T-cell core epitope. Pediatr Allergy Immunol 19:592-598
11. Inoue R, Matsushita S, Kaneko H, Shinoda S, Sakaguchi H, Nishimura Y, Kondo N 2001 Identification of beta-lactoglobulin-derived peptides and class II HLA molecules recognized by T cells from patients with milk allergy. Clin Exp Allergy 31:1126-1134 (Pubitemid 32862844)
12. Beyer K, Castro R, Birnbaum A, Benkov K, Pittman N, Sampson HA 2002 Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile. J Allergy Clin Immunol 109:707-713 (Pubitemid 34327201)
13. Tsuge I, Kondo Y, Tokuda R, Kakami M, Kawamura M, Nakajima Y, Komatsubara R, Yamada K, Urisu A 2006 Allergen-specific helper T cell response in patients with cow's milk allergy: simultaneous analysis of proliferation and cytokine production by carboxyfluorescein succinimidyl ester dilution assay. Clin Exp Allergy 36:1538-1545 (Pubitemid 44902931)
14. Crittenden RG, Bennett LE 2005 Cow's milk allergy: a complex disorder. J Am Coll Nutr 24:582S-591S (Pubitemid 46202338)
15. Karlsson MR, Rugtveit J, Brandtzaeg P 2004 Allergen-responsive CD4+CD25+regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 199:1679-1688 (Pubitemid 38822001)
16. Shreffler WG, Wanich N, Moloney M, Nowak-Wegrzyn A, Sampson HA 2009 Association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein. J Allergy Clin Immunol 123:43-52
17. Akdis M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, Crameri R, Thunberg S, Deniz G, Valenta R, Fiebig H, Kegel C, Disch R, Schmidt-Weber CB, Blaser K, Akdis CA 2004 Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 199:1567-1575 (Pubitemid 38780411)
18. Turcanu V, Maleki SJ, Lack G 2003 Characterization of lymphocyte responses to peanuts in normal children, peanut-allergic children, and allergic children who acquired tolerance to peanuts. J Clin Invest 111:1065-1072 (Pubitemid 36397483)
19. Maggi L, Santarlasci V, Liotta F, Frosali F, Angeli R, Cosmi L, Maggi E, Romagnani S, Annunziato F 2007 Demonstration of circulating allergen-specific CD4+CD25highFoxp3 T-regulatory cells in both nonatopic and atopic individuals. J Allergy Clin Immunol 120:429-436 (Pubitemid 47411530)
20. Berni Canani R, Ruotolo S, Discepolo V, Troncone R 2008 The diagnosis of food allergy in children. Curr Opin Pediatr 20:584-589
21. Gianfrani C, Levings MK, Sartirana C, Mazzarella G, Barba G, Zanzi D, Camarca A, Iaquinto G, Giardullo N, Auricchio S, Troncone R, Roncarolo MG 2006 Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells. J Immunol 177:4178-4186 (Pubitemid 44359953)
22. Ng TW, Holt PG, Prescott SL 2002 Cellular immune responses to ovalbumin and house dust mite in egg-allergic children. Allergy 57:207-214 (Pubitemid 34250751)
23. Sakaguchi H, Inoue R, Kaneko H, Watanabe M, Suzuki K, Kato Z, Matsushita S, Kondo N 2002 Interaction among human leucocyte antigen-peptide-T cell receptor complexes in cow's milk allergy: the significance of human leucocyte antigen and T cell receptor-complementarity determining region 3 loops. Clin Exp Allergy 32:762-770 (Pubitemid 34534025)
24. Kondo N, Fukutomi O, Agata H, Motoyoshi F, Shinoda S, Kobayashi Y, Kuwabara N, Kameyama T, Orii T 1993 The role of T lymphocytes in patients with foodsensitive atopic dermatitis. J Allergy Clin Immunol 91:658-668 (Pubitemid 23062937)
25. Hoffman KM, Ho DG, Sampson HA 1997 Evaluation of the usefulness of lymphocyte proliferation assays in the diagnosis of allergy to cow's milk. J Allergy Clin Immunol 99:360-366 (Pubitemid 27123916)
26. Savilahti EM, Karinen S, Salo HM, Klemetti P, Saarinen KM, Klemola T, Kuitunen M, Hautaniemi S, Savilahti E, Vaarala O 2010 Combined T regulatory cell and Th2 expression profile identifies children with cow's milk allergy. Clin Immunol 136:16-20
27. Hawrylowicz CM, O'Garra A 2005 Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol 5:271-283 (Pubitemid 40516153)
28. Brix S, Bovetto L, Fritsché R, Barkholt V, Frøkiaer H 2003 Immunostimulatory potential of beta-lactoglobulin preparations: effects caused by endotoxin contamination. J Allergy Clin Immunol 112:1216-1222 (Pubitemid 37550019)
29. Yamazaki K, Murray JA, Kita H 2008 Innate immunomodulatory effects of cereal grains through induction of IL-10. J Allergy Clin Immunol 121:172-178
30. Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A 2010 Molecular determinants of T cell epitope recognition to the common Timothy grass allergen. J Immunol 185:943-955
31. Souwer Y, Szegedi K, Kapsenberg ML, de Jong EC 2010 IL-17 and IL-22 in atopic allergic disease. Curr Opin Immunol 22:821-826