Characterization of T cell epitopes in αs1-casein in cow's milk allergic, atopic and non-atopic children

Clinical and Experimental Allergy

Volumn 36, Issue 3, 2006, Pages 303-310

  Ruiter, B ^a   Tregoat V ^b   M'Rabet, L ^b   Garssen, J ^b,c   Bruijnzeel Koomen, C A F M ^a   Knol, E F ^a   Van Hoffen, E ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NUMICO RESEARCH   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

s1 casein; Atopy; Cow's milk allergy; Cytokine; IL 10; Immunodominant; T cell epitope; Tolerance

Indexed keywords

ALPHA S1 CASEIN; AMINO ACID; CASEIN; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; MILK PROTEIN; PEPTIDE; T LYMPHOCYTE ANTIGEN; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG;

ADOLESCENT; AMINO ACID SEQUENCE; ANTIGEN SPECIFICITY; ARTICLE; ATOPY; CELLULAR IMMUNITY; CHILD; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; INFANT; LYMPHOCYTE CULTURE; LYMPHOCYTE PROLIFERATION; MILK ALLERGY; MOLECULAR RECOGNITION; NEWBORN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN TARGETING; T LYMPHOCYTE ACTIVATION; TH1 CELL; TH2 CELL;

ADOLESCENT; AMINO ACID SEQUENCE; ANIMALS; CASEINS; CELL LINE; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; CYTOKINES; DOUBLE-BLIND METHOD; EPITOPES, T-LYMPHOCYTE; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNE TOLERANCE; IMMUNODOMINANT EPITOPES; INFANT; LYMPHOCYTE ACTIVATION; MILK; MILK HYPERSENSITIVITY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 33644759221     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02436.x     Document Type: Article

References (21)

1. Høst A Halken S Jacobsen HP Estmann A Mortensen S Mygil S. The natural course of cow's milk protein allergy/intolerance [abstract] J Allergy Clin Immunol 1997 99 S490
2. Wal J-M. Bovine milk allergenicity Ann Allergy Asthma Immunol 2004 93 S2 11
3. Bernard H Créminon C Yvon M Wal J-M. Specificity of the human IgE response to the different purified caseins in allergy to cow's milk proteins Int Arch Allergy Immunol 1998 115 235 44
4. Kumosinski TF Brown EM Farrell Jr. HM. Three-dimensional molecular modeling of bovine caseins αs1-casein J Dairy Sci 1991 74 2889 95
5. Chatchatee P Järvinen K-M Bardina L Beyer K Sampson HA. Identification of IgE- and IgG-binding epitopes on αs1-casein differences in patients with persistent and transient cow's milk allergy J Allergy Clin Immunol 2001 107 379 83
6. Järvinen K-M Beyer K Vila L Chatchatee P Busse PJ Sampson HA. B-cell epitopes as a screening instrument for persistent cow's milk allergy J Allergy Clin Immunol 2002 110 293 97
7. Nakajima-Adachi H Hachimura S Ise W et al Determinant analysis of IgE and IgG4 antibodies and T cells specific for bovine αs1-casein from the same patients allergic to cow's milk existence of αs1-casein-specific B cells and T cells characteristic in cow's milk allergy J Allergy Clin Immunol 1998 101 660 71
8. Elsayed S Eriksen J Oysaed LK Idsoe R Hill DJ. T cell recognition pattern of bovine milk αs1-casein and its peptides Mol Immunol 2004 41 1225 34
9. Schade RP Van Ieperen-Van Dijk AG Van Reijsen FC et al Differences in antigen-specific T cell responses between infants with atopic dermatitis with and without cow's milk allergy relevance of Th2 cytokines J Allergy Clin Immunol 2000 106 1155 62
10. Tiemessen MM Van Ieperen-Van Dijk AG Bruijnzeel-Koomen CAFM Garssen J Knol EF Van Hoffen E. Cow's milk-specific T cell reactivity of children with and without persistent cow's milk allergy key role for IL-10 J Allergy Clin Immunol 2004 113 932 9
11. Carballido JM Carballido-Perrig N Kagi MK et al T cell epitope specificity in human allergic and non-allergic subjects to bee venom phospholipase A2 J Immunol 1993 150 3582 91
12. Ebner C Schenk S Najafian N et al Non-allergic individuals recognize the same T cell epitopes of Bet v 1, the major birch pollen allergen, as atopic patients J Immunol 1995 154 1932 40
13. Haselden BM Syrigou E Jones M et al Proliferation and release of IL-5 and IFNγ by peripheral blood mononuclear cells from cat-allergic asthmatics and rhinitics, non-cat-allergic asthmatics, and normal controls to peptides derived from Fel d 1 chain 1 J Allergy Clin Immunol 2001 108 349 56
14. Bohle B Zwölfer B Fischer GF et al Characterization of the human T cell response to antigen 5 from Vespula vulgaris (Ves v 5) Clin Exp Allergy 2005 35 367 73
15. Punnonen J Aversa G Cocks BG et al Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells Proc Natl Acad Sci USA 1993 90 3730 4
16. Reefer AJ Carneiro RM Custis NJ et al A role for IL-10-mediated HLA-DR7-restricted T cell-dependent events in development of the modified Th2 response to cat allergen J Immunol 2004 172 2763 72
17. Akdis CA Blesken T Akdis M Wuthrich B Blaser K. Role of interleukin 10 in specific immunotherapy J Clin Invest 1998 102 98 106
18. Kane P Erickson J Fewtrell C Baird B Holowka D. Cross-linking of IgE-receptor complexes at the cell surface synthesis and characterization of a long bivalent hapten that is capable of triggering mast cells and rat basophilic leukemia cells Mol Immunol 1986 23 783 90
19. Müller U Akdis CA Fricker M et al Succesful immunotherapy with T cell epitope peptides of bee venom phospholipase A2 induces specific T cell allergy in patients allergic to bee venom J Allergy Clin Immunol 1998 101 747 54
20. Oldfield WL Larché M Kay AB. Effect of T cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats a randomised controlled trial Lancet 2002 360 47 53
21. Hirahara K Hisatsune T Choi CY Kaminogawa S. Profound immunological tolerance in the antibody response against bovine αs1-casein induced by intradermal administration of a dominant T cell determinant Clin Immunol Immunopathol 1995 76 12 8