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Volumn 27, Issue 8, 2011, Pages 919-924

Mast cell stabilization: Novel medication for obesity and diabetes

Author keywords

Cromolyn; Diabetes; Ketotifen (Zaditor); Mast cell; Obesity

Indexed keywords

CROMOGLYCATE DISODIUM; KETOTIFEN; KETOTIFEN FUMARATE;

EID: 80855138406     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.1272     Document Type: Review
Times cited : (46)

References (61)
  • 1
    • 61449100408 scopus 로고    scopus 로고
    • IgE influences the number and function of mature mast cells, but not progenitor recruitment in allergic pulmonary inflammation
    • Mathias CB, Freyschmidt EJ, Caplan B, et al. IgE influences the number and function of mature mast cells, but not progenitor recruitment in allergic pulmonary inflammation. J Immunol 2009; 182(4): 2416-2424.
    • (2009) J Immunol , vol.182 , Issue.4 , pp. 2416-2424
    • Mathias, C.B.1    Freyschmidt, E.J.2    Caplan, B.3
  • 3
    • 9244230028 scopus 로고    scopus 로고
    • Mast cell contribution to angiogenesis related to tumour progression
    • Ribatti D, Crivellato E, Roccaro AM, Ria R, Vacca A. Mast cell contribution to angiogenesis related to tumour progression. Clin Exp Allergy 2004; 34(11): 1660-1664.
    • (2004) Clin Exp Allergy , vol.34 , Issue.11 , pp. 1660-1664
    • Ribatti, D.1    Crivellato, E.2    Roccaro, A.M.3    Ria, R.4    Vacca, A.5
  • 4
    • 77957872537 scopus 로고    scopus 로고
    • Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice
    • Chichlowski M, Westwood GS, Abraham SN, Hale LP. Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice. PLoS One 2010; 5(8): e12220.
    • (2010) PLoS One , vol.5 , Issue.8
    • Chichlowski, M.1    Westwood, G.S.2    Abraham, S.N.3    Hale, L.P.4
  • 6
    • 72949098107 scopus 로고    scopus 로고
    • Basophils and mast cells in renal injury
    • Mack M, Rosenkranz AR. Basophils and mast cells in renal injury. Kidney Int 2009; 76(11): 1142-1147.
    • (2009) Kidney Int , vol.76 , Issue.11 , pp. 1142-1147
    • Mack, M.1    Rosenkranz, A.R.2
  • 7
    • 34248177826 scopus 로고    scopus 로고
    • Synovial mast cells: role in acute and chronic arthritis
    • Nigrovic PA, Lee DM. Synovial mast cells: role in acute and chronic arthritis. Immunol Rev 2007; 217: 19-37.
    • (2007) Immunol Rev , vol.217 , pp. 19-37
    • Nigrovic, P.A.1    Lee, D.M.2
  • 8
    • 34250014988 scopus 로고    scopus 로고
    • Mast cells promote atherosclerosis by releasing proinflammatory cytokines
    • Sun J, Sukhova GK, Wolters PJ, et al. Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat Med 2007; 13(6): 719-724.
    • (2007) Nat Med , vol.13 , Issue.6 , pp. 719-724
    • Sun, J.1    Sukhova, G.K.2    Wolters, P.J.3
  • 9
    • 36048932955 scopus 로고    scopus 로고
    • Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice
    • Sun J, Sukhova GK, Yang M, et al. Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in mice. J Clin Invest 2007; 117(11): 3359-3368.
    • (2007) J Clin Invest , vol.117 , Issue.11 , pp. 3359-3368
    • Sun, J.1    Sukhova, G.K.2    Yang, M.3
  • 10
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009; 15(8): 940-945.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3
  • 11
    • 79953713651 scopus 로고    scopus 로고
    • Biological implications of preformed mast cell mediators
    • Lundequist A, Pejler G. Biological implications of preformed mast cell mediators. Cell Mol Life Sci 2011; 68(6): 965-975.
    • (2011) Cell Mol Life Sci , vol.68 , Issue.6 , pp. 965-975
    • Lundequist, A.1    Pejler, G.2
  • 12
    • 79960150092 scopus 로고    scopus 로고
    • Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases
    • Qin Y, Shi GP. Cysteinyl cathepsins and mast cell proteases in the pathogenesis and therapeutics of cardiovascular diseases. Pharmacol Ther 2011; 131(3): 338-350.
    • (2011) Pharmacol Ther , vol.131 , Issue.3 , pp. 338-350
    • Qin, Y.1    Shi, G.P.2
  • 13
    • 22844437863 scopus 로고    scopus 로고
    • Endocrine and signalling role of adipose tissue: new perspectives on fat
    • Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand 2005; 184(4): 285-293.
    • (2005) Acta Physiol Scand , vol.184 , Issue.4 , pp. 285-293
    • Trayhurn, P.1
  • 14
    • 0034852332 scopus 로고    scopus 로고
    • Adipose tissues display differential phagocytic and microbicidal activities depending on their localization
    • Villena JA, Cousin B, Pénicaud L, Casteilla L. Adipose tissues display differential phagocytic and microbicidal activities depending on their localization. Int J Obes Relat Metab Disord 2001; 25(9): 1275-1280.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , Issue.9 , pp. 1275-1280
    • Villena, J.A.1    Cousin, B.2    Pénicaud, L.3    Casteilla, L.4
  • 16
    • 9144223683 scopus 로고    scopus 로고
    • Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
    • Xu H, Barnes GT, Yang Q, et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003; 112(12): 1821-1830.
    • (2003) J Clin Invest , vol.112 , Issue.12 , pp. 1821-1830
    • Xu, H.1    Barnes, G.T.2    Yang, Q.3
  • 17
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009; 15(8): 930-939.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 18
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009; 15(8): 914-920.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 19
    • 68349137821 scopus 로고    scopus 로고
    • Normalization of obesity-associated insulin resistance through immunotherapy
    • Winer S, Chan Y, Paltser G, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009; 15(8): 921-929.
    • (2009) Nat Med , vol.15 , Issue.8 , pp. 921-929
    • Winer, S.1    Chan, Y.2    Paltser, G.3
  • 20
    • 75149169811 scopus 로고    scopus 로고
    • Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
    • Ohmura K, Ishimori N, Ohmura Y, et al. Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler Thromb Vasc Biol 2010; 30(2): 193-199.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.2 , pp. 193-199
    • Ohmura, K.1    Ishimori, N.2    Ohmura, Y.3
  • 21
    • 33748992313 scopus 로고    scopus 로고
    • Adipocytokines: mediators linking adipose tissue, inflammation and immunity
    • Tilg H, Moschen AR. Adipocytokines: mediators linking adipose tissue, inflammation and immunity. Nat Rev Immunol 2006; 6(10): 772-783.
    • (2006) Nat Rev Immunol , vol.6 , Issue.10 , pp. 772-783
    • Tilg, H.1    Moschen, A.R.2
  • 22
    • 33947730162 scopus 로고
    • Mast cell content and fatty acid metabolism in the epididymal fat pad of obese mice
    • Hellman B, Larsson S, Westman S. Mast cell content and fatty acid metabolism in the epididymal fat pad of obese mice. Acta Physiol Scand 1963; 58: 255-262.
    • (1963) Acta Physiol Scand , vol.58 , pp. 255-262
    • Hellman, B.1    Larsson, S.2    Westman, S.3
  • 23
    • 0013844346 scopus 로고
    • Studies in obese-hyperglycemic mice
    • Hellman B. Studies in obese-hyperglycemic mice. Ann N Y Acad Sci 1965; 131(1): 541-558.
    • (1965) Ann N Y Acad Sci , vol.131 , Issue.1 , pp. 541-558
    • Hellman, B.1
  • 24
    • 34047214102 scopus 로고    scopus 로고
    • Overweight, obesity, and incident asthma: a meta analysis of prospective epidemiologic studies
    • Beuther DA, Sutherland ER. Overweight, obesity, and incident asthma: a meta analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007; 175(7): 661-666.
    • (2007) Am J Respir Crit Care Med , vol.175 , Issue.7 , pp. 661-666
    • Beuther, D.A.1    Sutherland, E.R.2
  • 25
    • 18144391936 scopus 로고    scopus 로고
    • The epidemiology of obesity and asthma
    • quiz 910.
    • Ford ES. The epidemiology of obesity and asthma. J Allergy Clin Immunol 2005; 115(5): 897-909; quiz 910.
    • (2005) J Allergy Clin Immunol , vol.115 , Issue.5 , pp. 897-909
    • Ford, E.S.1
  • 26
    • 42749091447 scopus 로고    scopus 로고
    • Asthma and obesity: common early-life influences in the inception of disease
    • quiz 1085-1086.
    • Litonjua AA, Gold DR. Asthma and obesity: common early-life influences in the inception of disease. J Allergy Clin Immunol 2008; 121(5): 1075-1084; quiz 1085-1086.
    • (2008) J Allergy Clin Immunol , vol.121 , Issue.5 , pp. 1075-1084
    • Litonjua, A.A.1    Gold, D.R.2
  • 28
    • 50949108389 scopus 로고    scopus 로고
    • The relationship between obesity and asthma severity and control in adults
    • Mosen DM, Schatz M, Magid DJ, Camargo CA, Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008; 122(3): 507-511.e6.
    • (2008) J Allergy Clin Immunol , vol.122 , Issue.3
    • Mosen, D.M.1    Schatz, M.2    Magid, D.J.3    Camargo Jr., C.A.4
  • 31
    • 33645230177 scopus 로고    scopus 로고
    • Increased bone fracture prevalence in postmenopausal women suffering from pollen-allergy
    • Ferencz V, Meszaros S, Csupor E, et al. Increased bone fracture prevalence in postmenopausal women suffering from pollen-allergy. Osteoporos Int 2006; 17(3): 484-491.
    • (2006) Osteoporos Int , vol.17 , Issue.3 , pp. 484-491
    • Ferencz, V.1    Meszaros, S.2    Csupor, E.3
  • 35
    • 49649113435 scopus 로고    scopus 로고
    • Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation
    • Johnston RA, Theman TA, Lu FL, Terry RD, Williams ES, Shore SA. Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation. J Appl Physiol 2008; 104(6): 1727-1735.
    • (2008) J Appl Physiol , vol.104 , Issue.6 , pp. 1727-1735
    • Johnston, R.A.1    Theman, T.A.2    Lu, F.L.3    Terry, R.D.4    Williams, E.S.5    Shore, S.A.6
  • 37
    • 33646589670 scopus 로고    scopus 로고
    • Increased pulmonary responses to acute ozone exposure in obese db/db mice
    • Lu FL, Johnston RA, Flynt L, et al. Increased pulmonary responses to acute ozone exposure in obese db/db mice. Am J Physiol Lung Cell Mol Physiol 2006; 290(5): L856-L865.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290 , Issue.5
    • Lu, F.L.1    Johnston, R.A.2    Flynt, L.3
  • 38
    • 33746516349 scopus 로고    scopus 로고
    • Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
    • Shore SA, Terry RD, Flynt L, Xu A, Hug C. Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol 2006; 118(2): 389-395.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.2 , pp. 389-395
    • Shore, S.A.1    Terry, R.D.2    Flynt, L.3    Xu, A.4    Hug, C.5
  • 39
    • 70349160768 scopus 로고    scopus 로고
    • Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling
    • Medoff BD, Okamoto Y, Leyton P, et al. Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol 2009; 41(4): 397-406.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , Issue.4 , pp. 397-406
    • Medoff, B.D.1    Okamoto, Y.2    Leyton, P.3
  • 40
    • 79251570613 scopus 로고    scopus 로고
    • Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils
    • Zhang J, Alcaide P, Liu L, et al. Regulation of endothelial cell adhesion molecule expression by mast cells, macrophages, and neutrophils. PLoS One 2011; 6(1): e14525.
    • (2011) PLoS One , vol.6 , Issue.1
    • Zhang, J.1    Alcaide, P.2    Liu, L.3
  • 41
    • 0019211131 scopus 로고
    • A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma
    • Clarke CW, May CS. A comparison of the efficacy of ketotifen (HC 20-511) with sodium cromoglycate (SCG) in skin test positive asthma. Br J Clin Pharmacol 1980; 10(5): 473-476.
    • (1980) Br J Clin Pharmacol , vol.10 , Issue.5 , pp. 473-476
    • Clarke, C.W.1    May, C.S.2
  • 42
    • 85004805756 scopus 로고
    • Effect of disodium cromoglycate on activation of human eosinophils and neutrophils following reversed (anti-IgE) anaphylaxis
    • Moqbel R, Walsh GM, Macdonald AJ, Kay B. Effect of disodium cromoglycate on activation of human eosinophils and neutrophils following reversed (anti-IgE) anaphylaxis. Clin Allergy 1986; 16(1): 73-83.
    • (1986) Clin Allergy , vol.16 , Issue.1 , pp. 73-83
    • Moqbel, R.1    Walsh, G.M.2    Macdonald, A.J.3    Kay, B.4
  • 43
    • 0020074529 scopus 로고
    • Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells
    • Pearce FL, Befus AD, Gauldie J, Bienenstock J. Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells. J Immunol 1982; 128(6): 2481-2486.
    • (1982) J Immunol , vol.128 , Issue.6 , pp. 2481-2486
    • Pearce, F.L.1    Befus, A.D.2    Gauldie, J.3    Bienenstock, J.4
  • 44
    • 0023122046 scopus 로고
    • Mast cells from the human intestinal lamina propria. Isolation, histochemical subtypes, and functional characterization
    • Befus AD, Dyck N, Goodacre R, Bienenstock J. Mast cells from the human intestinal lamina propria. Isolation, histochemical subtypes, and functional characterization. J Immunol 1987; 138(8): 2604-2610.
    • (1987) J Immunol , vol.138 , Issue.8 , pp. 2604-2610
    • Befus, A.D.1    Dyck, N.2    Goodacre, R.3    Bienenstock, J.4
  • 46
    • 4444324067 scopus 로고    scopus 로고
    • Tranilast reduces mesenteric vascular collagen deposition and chymase-positive mast cells in experimental diabetes
    • Jones SE, Gilbert RE, Kelly DJ. Tranilast reduces mesenteric vascular collagen deposition and chymase-positive mast cells in experimental diabetes. J Diabetes Complicat 2004; 18(5): 309-315.
    • (2004) J Diabetes Complicat , vol.18 , Issue.5 , pp. 309-315
    • Jones, S.E.1    Gilbert, R.E.2    Kelly, D.J.3
  • 47
    • 4444232912 scopus 로고    scopus 로고
    • Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma
    • Djukanović R, Wilson SJ, Kraft M, et al. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med 2004; 170(6): 583-593.
    • (2004) Am J Respir Crit Care Med , vol.170 , Issue.6 , pp. 583-593
    • Djukanović, R.1    Wilson, S.J.2    Kraft, M.3
  • 48
    • 68349095055 scopus 로고    scopus 로고
    • The immunoglobulin E-Toll-like receptor network
    • Novak N, Bieber T, Peng WM. The immunoglobulin E-Toll-like receptor network. Int Arch Allergy Immunol 2010; 151(1): 1-7.
    • (2010) Int Arch Allergy Immunol , vol.151 , Issue.1 , pp. 1-7
    • Novak, N.1    Bieber, T.2    Peng, W.M.3
  • 49
    • 16244397342 scopus 로고    scopus 로고
    • An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment
    • Meltzer EO, Berkowitz RB, Grossbard EB. An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment. J Allergy Clin Immunol 2005; 115(4): 791-796.
    • (2005) J Allergy Clin Immunol , vol.115 , Issue.4 , pp. 791-796
    • Meltzer, E.O.1    Berkowitz, R.B.2    Grossbard, E.B.3
  • 50
    • 70349763716 scopus 로고    scopus 로고
    • Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation
    • Sun J, Zhang J, Lindholt JS, et al. Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation 2009; 120(11): 973-982.
    • (2009) Circulation , vol.120 , Issue.11 , pp. 973-982
    • Sun, J.1    Zhang, J.2    Lindholt, J.S.3
  • 51
    • 79958142090 scopus 로고    scopus 로고
    • Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation
    • Zhang J, Sun J, Lindholt JS, et al. Mast cell tryptase deficiency attenuates mouse abdominal aortic aneurysm formation. Circ Res 2011; 108(11): 1316-1327.
    • (2011) Circ Res , vol.108 , Issue.11 , pp. 1316-1327
    • Zhang, J.1    Sun, J.2    Lindholt, J.S.3
  • 52
    • 33750338721 scopus 로고    scopus 로고
    • Desquamation of human coronary artery endothelium by human mast cell proteases: implications for plaque erosion
    • Mäyränpää MI, Heikkilä HM, Lindstedt KA, Walls AF, Kovanen PT. Desquamation of human coronary artery endothelium by human mast cell proteases: implications for plaque erosion. Coron Artery Dis 2006; 17(7): 611-621.
    • (2006) Coron Artery Dis , vol.17 , Issue.7 , pp. 611-621
    • Mäyränpää, M.I.1    Heikkilä, H.M.2    Lindstedt, K.A.3    Walls, A.F.4    Kovanen, P.T.5
  • 53
    • 0031010717 scopus 로고    scopus 로고
    • Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor
    • Blair RJ, Meng H, Marchese MJ, et al. Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor. J Clin Invest 1997; 99(11): 2691-2700.
    • (1997) J Clin Invest , vol.99 , Issue.11 , pp. 2691-2700
    • Blair, R.J.1    Meng, H.2    Marchese, M.J.3
  • 54
    • 0034008405 scopus 로고    scopus 로고
    • Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model
    • Muramatsu M, Katada J, Hayashi I, Majima M. Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model. J Biol Chem 2000; 275(8): 5545-5552.
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5545-5552
    • Muramatsu, M.1    Katada, J.2    Hayashi, I.3    Majima, M.4
  • 55
    • 34547564529 scopus 로고    scopus 로고
    • Cathepsin L activity controls adipogenesis and glucose tolerance
    • Yang M, Zhang Y, Pan J, et al. Cathepsin L activity controls adipogenesis and glucose tolerance. Nat Cell Biol 2007; 9(8): 970-977.
    • (2007) Nat Cell Biol , vol.9 , Issue.8 , pp. 970-977
    • Yang, M.1    Zhang, Y.2    Pan, J.3
  • 56
    • 57549118164 scopus 로고    scopus 로고
    • Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice
    • Yang M, Sun J, Zhang T, et al. Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice. Arterioscler Thromb Vasc Biol 2008; 28(12): 2202-2208.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.12 , pp. 2202-2208
    • Yang, M.1    Sun, J.2    Zhang, T.3
  • 57
    • 45749117243 scopus 로고    scopus 로고
    • A functional role of gelatinase A in the development of nutritionally induced obesity in mice
    • Van Hul M, Lijnen HR. A functional role of gelatinase A in the development of nutritionally induced obesity in mice. J Thromb Haemost 2008; 6(7): 1198-1206.
    • (2008) J Thromb Haemost , vol.6 , Issue.7 , pp. 1198-1206
    • Van Hul, M.1    Lijnen, H.R.2
  • 58
    • 77957559421 scopus 로고    scopus 로고
    • Genetic link between obesity and MMP14-dependent adipogenic collagen turnover
    • Chun TH, Inoue M, Morisaki H, et al. Genetic link between obesity and MMP14-dependent adipogenic collagen turnover. Diabetes 2010; 59(10): 2484-2494.
    • (2010) Diabetes , vol.59 , Issue.10 , pp. 2484-2494
    • Chun, T.H.1    Inoue, M.2    Morisaki, H.3
  • 59
    • 0036188833 scopus 로고    scopus 로고
    • Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study
    • Tremaine WJ, Brzezinski A, Katz JA, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther 2002; 16(3): 407-413.
    • (2002) Aliment Pharmacol Ther , vol.16 , Issue.3 , pp. 407-413
    • Tremaine, W.J.1    Brzezinski, A.2    Katz, J.A.3
  • 60
    • 0035912953 scopus 로고    scopus 로고
    • Heparin antagonists are potent inhibitors of mast cell tryptase
    • Hallgren J, Estrada S, Karlson U, Alving K, Pejler G. Heparin antagonists are potent inhibitors of mast cell tryptase. Biochemistry 2001; 40(24): 7342-7349.
    • (2001) Biochemistry , vol.40 , Issue.24 , pp. 7342-7349
    • Hallgren, J.1    Estrada, S.2    Karlson, U.3    Alving, K.4    Pejler, G.5
  • 61
    • 1342281660 scopus 로고    scopus 로고
    • Vascular chymase: pathophysiological role and therapeutic potential of inhibition
    • Doggrell SA, Wanstall JC. Vascular chymase: pathophysiological role and therapeutic potential of inhibition. Cardiovasc Res 2004; 61(4): 653-662.
    • (2004) Cardiovasc Res , vol.61 , Issue.4 , pp. 653-662
    • Doggrell, S.A.1    Wanstall, J.C.2


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