Defining the role of essential genes in human disease

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Dickerson, Jonathan E ^a,b   Zhu, Ana ^a,c   Robertson, David L ^a   Hentges, Kathryn E ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; BIRTH DEFECT; CELLULAR DISTRIBUTION; CHROMOSOME TRANSLOCATION; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE GENE; DISEASE LETHAL GENE; DISEASE VIABLE GENE; ESSENTIAL GENE; GAIN OF FUNCTION MUTATION; GENE CONVERSION; GENE INACTIVATION; GENE SEGREGATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HOUSEKEEPING GENE; HUMAN; HUMAN GENOME; KNOCKOUT MOUSE; LETHAL GENE; LOSS OF FUNCTION MUTATION; NONHUMAN; ORTHOLOGY; PHENOTYPE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SPONTANEOUS ABORTION; TUMOR GENE; ANIMAL; DISEASES; GENETICS; MOUSE; PHYSIOLOGY;

ANIMALS; DISEASE; GENES, ESSENTIAL; HUMANS; MICE; PROTEIN INTERACTION MAPS;

EID: 80855134313     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027368     Document Type: Article

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