Enhancement of the fraction of the active form of an antitumor drug topotecan via an injectable hydrogel

Journal of Controlled Release

Volumn 156, Issue 1, 2011, Pages 21-27

  Chang, Guangtao ^a   Ci, Tianyuan ^a   Yu, Lin ^a   Ding, Jiandong ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Anticancer; Camptothecin (CPT); Drug material interaction; Injectable hydrogel; Local chemotherapy; Topotecan (TPT)

Indexed keywords

BIOMATERIALS; BODY FLUIDS; CARBOXYLATION; CHEMOTHERAPY; CONTROLLED DRUG DELIVERY; DRUG INTERACTIONS; HYDROPHOBICITY; LACTIC ACID; PH EFFECTS; POLYETHYLENE GLYCOLS; TARGETED DRUG DELIVERY;

ANTICANCER; CAMPTOTHECIN (CPT); DRUG MATERIALS; INJECTABLE HYDROGELS; TOPOTECAN;

HYDROGELS;

BIOMATERIAL; CAMPTOTHECIN; LACTONE; MACROGOL; POLYGLACTIN; TOPOTECAN;

ACIDITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; CANCER INHIBITION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ENCAPSULATION; FEMALE; HYDROGEL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

EID: 80855130910     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.008     Document Type: Article

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