-
1
-
-
0142059776
-
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
-
Bhave G, Hu HJ, Glauner KS, Zhu W, Wang H, Brasier DJ, Oxford GS, and Gereau RWT 4th (2003) Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1). Proc Natl Acad Sci U S A 100: 12480-12485.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12480-12485
-
-
Bhave, G.1
Hu, H.J.2
Glauner, K.S.3
Zhu, W.4
Wang, H.5
Brasier, D.J.6
Oxford, G.S.7
Gereau, R.W.T.8
-
2
-
-
0037104657
-
cAMP -dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation
-
Bhave G, Zhu W, Wang H, Brasier DJ, Oxford GS, and Gereau RWT (2002) cAMP -dependent protein kinase regulates desensitization of the capsaicin receptor (VR1) by direct phosphorylation. Neuron 35: 721-731.
-
(2002)
Neuron
, vol.35
, pp. 721-731
-
-
Bhave, G.1
Zhu, W.2
Wang, H.3
Brasier, D.J.4
Oxford, G.S.5
Gereau, R.W.T.6
-
3
-
-
0033166535
-
Specific involvement of PKC -epsilon in sensitization of the neuronal response to painful heat
-
Cesare P, Dekker LV, Sardini A, Parker PJ, and McNaughton PA (1999) Specific involvement of PKC -epsilon in sensitization of the neuronal response to painful heat. Neuron 23: 617-624.
-
(1999)
Neuron
, vol.23
, pp. 617-624
-
-
Cesare, P.1
Dekker, L.V.2
Sardini, A.3
Parker, P.J.4
McNaughton, P.A.5
-
4
-
-
0030446311
-
A novel heat -activated current in nociceptive neurons and its sensitization by bradykinin
-
Cesare P and McNaughton P (1996) A novel heat -activated current in nociceptive neurons and its sensitization by bradykinin. Proc Natl Acad Sci U S A 93: 15435-15439.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 15435-15439
-
-
Cesare, P.1
McNaughton, P.2
-
5
-
-
5644280204
-
Cloning and pharmacological characterization of mouse TRPV1
-
Correll CC, Phelps PT, Anthes JC, Umland S, and Greenfeder S (2004) Cloning and pharmacological characterization of mouse TRPV1. Neurosci Lett 370: 55-60.
-
(2004)
Neurosci Lett
, vol.370
, pp. 55-60
-
-
Correll, C.C.1
Phelps, P.T.2
Anthes, J.C.3
Umland, S.4
Greenfeder, S.5
-
6
-
-
2442498381
-
Molecular determinants of vanilloid sensitivity in TRPV1
-
Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, Wild K, Louis JC, and Treanor JJ (2004) Molecular determinants of vanilloid sensitivity in TRPV1. J Biol Chem 279: 20283-20295.
-
(2004)
J Biol Chem
, vol.279
, pp. 20283-20295
-
-
Gavva, N.R.1
Klionsky, L.2
Qu, Y.3
Shi, L.4
Tamir, R.5
Edenson, S.6
Zhang, T.J.7
Viswanadhan, V.N.8
Toth, A.9
Pearce, L.V.10
Vanderah, T.W.11
Porreca, F.12
Blumberg, P.M.13
Lile, J.14
Sun, Y.15
Wild, K.16
Louis, J.C.17
Treanor, J.J.18
-
7
-
-
33747609110
-
Functional mapping of the transient receptor potential vanilloid 1 intracellular binding site
-
Johnson DM, Garrett EM, Rutter R, Bonnert TP, Gao YD, Middleton RE, and Sutton KG (2006) Functional mapping of the transient receptor potential vanilloid 1 intracellular binding site. Mol Pharmacol 70: 1005-1012.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1005-1012
-
-
Johnson, D.M.1
Garrett, E.M.2
Rutter, R.3
Bonnert, T.P.4
Gao, Y.D.5
Middleton, R.E.6
Sutton, K.G.7
-
8
-
-
0036183319
-
Molecular basis for species -specific sensitivity to "hot" chili peppers
-
Jordt SE and Julius D (2002) Molecular basis for species -specific sensitivity to "hot" chili peppers. Cell 108 (3): 421-430.
-
(2002)
Cell
, vol.108
, Issue.3
, pp. 421-430
-
-
Jordt, S.E.1
Julius, D.2
-
9
-
-
0037113918
-
Agonist recognition sites in the cytosolic tails of vanilloid receptor 1
-
Jung J, Lee SY, Hwang SW, Cho H, Shin J, Kang YS, Kim S, and Oh U (2002) Agonist recognition sites in the cytosolic tails of vanilloid receptor 1. J Biol Chem 277: 44448-44454.
-
(2002)
J Biol Chem
, vol.277
, pp. 44448-44454
-
-
Jung, J.1
Lee, S.Y.2
Hwang, S.W.3
Cho, H.4
Shin, J.5
Kang, Y.S.6
Kim, S.7
Oh, U.8
-
10
-
-
85047690839
-
Deletion of vanilloid receptor 1 -expressing primary afferent neurons for pain control
-
Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, and Iadarola MJ (2004) Deletion of vanilloid receptor 1 -expressing primary afferent neurons for pain control. J Clin Invest 113: 1344-1352.
-
(2004)
J Clin Invest
, vol.113
, pp. 1344-1352
-
-
Karai, L.1
Brown, D.C.2
Mannes, A.J.3
Connelly, S.T.4
Brown, J.5
Gandal, M.6
Wellisch, O.M.7
Neubert, J.K.8
Olah, Z.9
Iadarola, M.J.10
-
11
-
-
42949125051
-
Pirt, a phosphoinositide -binding protein, functions as a regulatory subunit of TRPV1
-
Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, and Dong X (2008) Pirt, a phosphoinositide -binding protein, functions as a regulatory subunit of TRPV1. Cell 133: 475-485.
-
(2008)
Cell
, vol.133
, pp. 475-485
-
-
Kim, A.Y.1
Tang, Z.2
Liu, Q.3
Patel, K.N.4
Maag, D.5
Geng, Y.6
Dong, X.7
-
12
-
-
33846269106
-
Genetic predictors for acute experimental cold and heat pain sensitivity in humans
-
Kim H, Mittal DP, Iadarola MJ, and Dionne RA (2006) Genetic predictors for acute experimental cold and heat pain sensitivity in humans. J Med Genet 43: e40.
-
(2006)
J Med Genet
, vol.43
-
-
Kim, H.1
Mittal, D.P.2
Iadarola, M.J.3
Dionne, R.A.4
-
13
-
-
2442420245
-
Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
-
Kim H, Neubert JK, San Miguel A, Xu K, Krishnaraju RK, Iadarola MJ, Goldman D, and Dionne RA (2004) Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament. Pain 109: 488-496.
-
(2004)
Pain
, vol.109
, pp. 488-496
-
-
Kim, H.1
Neubert, J.K.2
San Miguel, A.3
Xu, K.4
Krishnaraju, R.K.5
Iadarola, M.J.6
Goldman, D.7
Dionne, R.A.8
-
14
-
-
0035889970
-
Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation
-
Kuzhikandathil EV, Wang H, Szabo T, Morozova N, Blumberg PM, and Oxford GS (2001) Functional analysis of capsaicin receptor (vanilloid receptor subtype 1) multimerization and agonist responsiveness using a dominant negative mutation. J Neurosci 21: 8697-8706.
-
(2001)
J Neurosci
, vol.21
, pp. 8697-8706
-
-
Kuzhikandathil, E.V.1
Wang, H.2
Szabo, T.3
Morozova, N.4
Blumberg, P.M.5
Oxford, G.S.6
-
15
-
-
0028285307
-
Irreversible conduction block in isolated nerve by high concentrations of local anesthetics
-
Lambert LA, Lambert DH, and Strichartz GR (1994) Irreversible conduction block in isolated nerve by high concentrations of local anesthetics. Anesthesiology 80: 1082-1093.
-
(1994)
Anesthesiology
, vol.80
, pp. 1082-1093
-
-
Lambert, L.A.1
Lambert, D.H.2
Strichartz, G.R.3
-
16
-
-
38849094740
-
The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons
-
Leffler A, Fischer MJ, Rehner D, Kienel S, Kistner K, Sauer SK, Gavva NR, Reeh PW, and Nau C (2008) The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons. J Clin Invest 118: 763-776.
-
(2008)
J Clin Invest
, vol.118
, pp. 763-776
-
-
Leffler, A.1
Fischer, M.J.2
Rehner, D.3
Kienel, S.4
Kistner, K.5
Sauer, S.K.6
Gavva, N.R.7
Reeh, P.W.8
Nau, C.9
-
17
-
-
34250190946
-
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
-
Lishko PV, Procko E, Jin X, Phelps CB, and Gaudet R (2007) The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity. Neuron 54: 905-918.
-
(2007)
Neuron
, vol.54
, pp. 905-918
-
-
Lishko, P.V.1
Procko, E.2
Jin, X.3
Phelps, C.B.4
Gaudet, R.5
-
19
-
-
42949117400
-
A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating
-
Myers BR, Bohlen CJ, and Julius D (2008) A yeast genetic screen reveals a critical role for the pore helix domain in TRP channel gating. Neuron 58: 362-373.
-
(2008)
Neuron
, vol.58
, pp. 362-373
-
-
Myers, B.R.1
Bohlen, C.J.2
Julius, D.3
-
20
-
-
34848889243
-
Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization
-
Novakova -Tousova K, Vyklicky L, Susankova K, Benedikt J, Samad A, Teisinger J, and Vlachova V (2007) Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization. Neuroscience 149: 144-154.
-
(2007)
Neuroscience
, vol.149
, pp. 144-154
-
-
Novakova-Tousova, K.1
Vyklicky, L.2
Susankova, K.3
Benedikt, J.4
Samad, A.5
Teisinger, J.6
Vlachova, V.7
-
21
-
-
28244489582
-
Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1
-
Ohta T, Komatsu R, Imagawa T, Otsuguro K, and Ito S (2005) Molecular cloning, functional characterization of the porcine transient receptor potential V1 (pTRPV1) and pharmacological comparison with endogenous pTRPV1. Biochem Pharmacol 71: 173-187.
-
(2005)
Biochem Pharmacol
, vol.71
, pp. 173-187
-
-
Ohta, T.1
Komatsu, R.2
Imagawa, T.3
Otsuguro, K.4
Ito, S.5
-
22
-
-
33751405456
-
Induction of total insensitivity to capsaicin and hypersensitivity to garlic extract in human by decreased expression of TRPV1
-
Park JJ, Lee J, Kim MA, Back SK, Hong SK, and Na HS (2007) Induction of total insensitivity to capsaicin and hypersensitivity to garlic extract in human by decreased expression of TRPV1. Neurosci Lett 411: 87-91.
-
(2007)
Neurosci Lett
, vol.411
, pp. 87-91
-
-
Park, J.J.1
Lee, J.2
Kim, M.A.3
Back, S.K.4
Hong, S.K.5
Na, H.S.6
-
23
-
-
18844439410
-
Cloning and functional characterization of dog transient receptor potential vanilloid receptor -1 (TRPV1)
-
Phelps PT, Anthes JC, and Correll CC (2005) Cloning and functional characterization of dog transient receptor potential vanilloid receptor -1 (TRPV1). Eur J Pharmacol 513: 57-66.
-
(2005)
Eur J Pharmacol
, vol.513
, pp. 57-66
-
-
Phelps, P.T.1
Anthes, J.C.2
Correll, C.C.3
-
24
-
-
2342439775
-
Identification of species -specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1
-
Phillips E, Reeve A, Bevan S, and McIntyre P (2004) Identification of species -specific determinants of the action of the antagonist capsazepine and the agonist PPAHV on TRPV1. J Biol Chem 279: 17165-17172.
-
(2004)
J Biol Chem
, vol.279
, pp. 17165-17172
-
-
Phillips, E.1
Reeve, A.2
Bevan, S.3
McIntyre, P.4
-
25
-
-
33845382786
-
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes
-
Razavi R, Chan Y, Afifiyan FN, Liu XJ, Wan X, Yantha J, Tsui H, Tang L, Tsai S, Santamaria P, Driver JP, Serreze D, Salter MW, and Dosch HM (2006) TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell 127: 1123-1135.
-
(2006)
Cell
, vol.127
, pp. 1123-1135
-
-
Razavi, R.1
Chan, Y.2
Afifiyan, F.N.3
Liu, X.J.4
Wan, X.5
Yantha, J.6
Tsui, H.7
Tang, L.8
Tsai, S.9
Santamaria, P.10
Driver, J.P.11
Serreze, D.12
Salter, M.W.13
Dosch, H.M.14
-
26
-
-
34447515681
-
Contribution of the putative inner -pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1)
-
Susankova K, Ettrich R, Vyklicky L, Teisinger J, and Vlachova V (2007) Contribution of the putative inner -pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1). J Neurosci 27: 7578-7585.
-
(2007)
J Neurosci
, vol.27
, pp. 7578-7585
-
-
Susankova, K.1
Ettrich, R.2
Vyklicky, L.3
Teisinger, J.4
Vlachova, V.5
-
27
-
-
33745263762
-
Reducing and oxidizing agents sensitize heat -activated vanilloid receptor (TRPV1) current
-
Susankova K, Tousova K, Vyklicky L, Teisinger J, and Vlachova V (2006) Reducing and oxidizing agents sensitize heat -activated vanilloid receptor (TRPV1) current. Mol Pharmacol 70: 383-394.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 383-394
-
-
Susankova, K.1
Tousova, K.2
Vyklicky, L.3
Teisinger, J.4
Vlachova, V.5
-
28
-
-
27644570846
-
Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor
-
Sutton KG, Garrett EM, Rutter AR, Bonnert TP, Jarolimek W, and Seabrook GR (2005) Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor. Br J Pharmacol 146: 702-711.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 702-711
-
-
Sutton, K.G.1
Garrett, E.M.2
Rutter, A.R.3
Bonnert, T.P.4
Jarolimek, W.5
Seabrook, G.R.6
-
29
-
-
36849090468
-
Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function
-
Tan PL, Barr T, Inglis PN, Mitsuma N, Huang SM, Garcia -Gonzalez MA, Bradley BA, Coforio S, Albrecht PJ, Watnick T, Germino GG, Beales PL, Caterina MJ, Leroux MR, Rice FL, and Katsanis N (2007) Loss of Bardet Biedl syndrome proteins causes defects in peripheral sensory innervation and function. Proc Natl Acad Sci U S A 104: 17524-17529.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17524-17529
-
-
Tan, P.L.1
Barr, T.2
Inglis, P.N.3
Mitsuma, N.4
Huang, S.M.5
Garcia-Gonzalez, M.A.6
Bradley, B.A.7
Coforio, S.8
Albrecht, P.J.9
Watnick, T.10
Germino, G.G.11
Beales, P.L.12
Caterina, M.J.13
Leroux, M.R.14
Rice, F.L.15
Katsanis, N.16
-
30
-
-
33644796336
-
Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant
-
Tian W, Fu Y, Wang DH, and Cohen DM (2006) Regulation of TRPV1 by a novel renally expressed rat TRPV1 splice variant. Am J Physiol Renal Physiol 290: F117-126.
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Tian, W.1
Fu, Y.2
Wang, D.H.3
Cohen, D.M.4
-
31
-
-
35248899861
-
' Sensing ' autoimmunity in type 1 diabetes
-
Tsui H, Razavi R, Chan Y, Yantha J, and Dosch HM (2007) ' Sensing ' autoimmunity in type 1 diabetes. Trends Mol Med 13: 405-413.
-
(2007)
Trends Mol Med
, vol.13
, pp. 405-413
-
-
Tsui, H.1
Razavi, R.2
Chan, Y.3
Yantha, J.4
Dosch, H.M.5
-
32
-
-
0037443098
-
Functional role of C -terminal cytoplasmic tail of rat vanilloid receptor 1
-
Vlachova V, Teisinger J, Susankova K, Lyfenko A, Ettrich R, and Vyklicky L (2003) Functional role of C -terminal cytoplasmic tail of rat vanilloid receptor 1. J Neurosci 23: 1340-1350.
-
(2003)
J Neurosci
, vol.23
, pp. 1340-1350
-
-
Vlachova, V.1
Teisinger, J.2
Susankova, K.3
Lyfenko, A.4
Ettrich, R.5
Vyklicky, L.6
-
33
-
-
33750427895
-
TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells
-
Vos MH, Neelands TR, McDonald HA, Choi W, Kroeger PE, Puttfarcken PS, Faltynek CR, Moreland RB, and Han P (2006) TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells. J Neurochem 99: 1088-1102.
-
(2006)
J Neurochem
, vol.99
, pp. 1088-1102
-
-
Vos, M.H.1
Neelands, T.R.2
McDonald, H.A.3
Choi, W.4
Kroeger, P.E.5
Puttfarcken, P.S.6
Faltynek, C.R.7
Moreland, R.B.8
Han, P.9
-
34
-
-
3342938159
-
Subtelomere FISH in 50 children with mental retardation and minor anomalies, identified by a checklist, detects 10 rearrangements including a de novo balanced translocation of chromosomes 17p13.3 and 20q13.33
-
Walter S, Sandig K, Hinkel GK, Mitulla B, Ounap K, Sims G, Sitska M, Utermann B, Viertel P, Kalscheuer V, and Bartsch O (2004) Subtelomere FISH in 50 children with mental retardation and minor anomalies, identified by a checklist, detects 10 rearrangements including a de novo balanced translocation of chromosomes 17p13.3 and 20q13.33. Am J Med Genet A 128: 364-373.
-
(2004)
Am J Med Genet A
, vol.128
, pp. 364-373
-
-
Walter, S.1
Sandig, K.2
Hinkel, G.K.3
Mitulla, B.4
Ounap, K.5
Sims, G.6
Sitska, M.7
Utermann, B.8
Viertel, P.9
Kalscheuer, V.10
Bartsch, O.11
-
35
-
-
4444258203
-
An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels
-
Wang C, Hu HZ, Colton CK, Wood JD, and Zhu MX (2004) An alternative splicing product of the murine trpv1 gene dominant negatively modulates the activity of TRPV1 channels. J Biol Chem 279: 37423-37430.
-
(2004)
J Biol Chem
, vol.279
, pp. 37423-37430
-
-
Wang, C.1
Hu, H.Z.2
Colton, C.K.3
Wood, J.D.4
Zhu, M.X.5
-
36
-
-
21344439776
-
Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N -glycosylation site N604
-
Wirkner K, Hognestad H, Jahnel R, Hucho F, and Illes P (2005) Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N -glycosylation site N604. Neuroreport 16: 997-1001.
-
(2005)
Neuroreport
, vol.16
, pp. 997-1001
-
-
Wirkner, K.1
Hognestad, H.2
Jahnel, R.3
Hucho, F.4
Illes, P.5
-
37
-
-
36549004459
-
Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene
-
Xu H, Tian W, Fu Y, Oyama TT, Anderson S, and Cohen DM (2007) Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. Am J Physiol Renal Physiol 293: F1865 -F1876.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Xu, H.1
Tian, W.2
Fu, Y.3
Oyama, T.T.4
Anderson, S.5
Cohen, D.M.6
-
38
-
-
29244484493
-
NGF rapidly increases membrane expression of TRPV1 heat -gated ion channels
-
Zhang X, Huang J, and McNaughton PA (2005) NGF rapidly increases membrane expression of TRPV1 heat -gated ion channels. EMBO J 24: 4211-4223.
-
(2005)
EMBO J
, vol.24
, pp. 4211-4223
-
-
Zhang, X.1
Huang, J.2
McNaughton, P.A.3
|