Vascular contribution of adrenomedullin to microcirculatory improvement in experimental colitis

European Journal of Pharmacology

Volumn 670, Issue 2-3, 2011, Pages 601-607

  Talero, Elena ^a   Alvarez De Sotomayor, Maria ^a   Sánchez Fidalgo, Susana ^a   Motilva, Virginia ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Adrenomedullin; Cyclooxygenase; Inflammatory bowel disease; Nitric oxide synthase; Small mesenteric artery

Indexed keywords

ADRENOMEDULLIN; CYCLOOXYGENASE 2; GAMMA INTERFERON; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MYELOPEROXIDASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NITRATE; NITRITE; PHENYLEPHRINE; TRINITROBENZENESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; CHRONIC DRUG ADMINISTRATION; COLITIS; CONTROLLED STUDY; MALE; MESENTERIC ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT;

ADRENOMEDULLIN; ANIMALS; BIOLOGICAL MARKERS; COLITIS; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATORY BOWEL DISEASES; MALE; MESENTERIC ARTERIES; MICROCIRCULATION; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHENYLEPHRINE; RATS; RATS, WISTAR; VASOCONSTRICTION;

EID: 80755186517     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.032     Document Type: Article

References (36)

1. M. Alvarez de Sotomayor, R. Bueno, C. Pérez-Guerrero, and M.D. Herrera Effect of L-carnitine and propionyl-L-carnitine on endothelial function of small mesenteric arteries from SHR J. Vasc. Res. 44 2007 354 364 (Pubitemid 47312656)
2. S. Ashizuka, N. Ishikawa, J. Kato, J. Yamaga, H. Inatsu, T. Eto, and K. Kitamura Effect of adrenomedullin administration on acetic acid-induced colitis in rats Peptides 26 2005 2610 2615 (Pubitemid 41676739)
3. S. Ashizuka, K. Inagaki-Ohara, K. Kuwasako, J. Kato, H. Inatsu, and K. Kitamura Adrenomedullin treatment reduces intestinal inflammation and maintains epithelial barrier function in mice administered dextran sulphate sodium Microbiol. Immunol. 53 2009 573 581
4. S.D. Brain, and A.D. Grant Vascular actions of calcitonin gene-related peptide and adrenomedullin Physiol. Rev. 84 2004 903 934 (Pubitemid 38823770)
5. D.C. Bunton, M.C. Petrie, C. Hillier, F. Johnston, and J.J. McMurray The clinical relevance of adrenomedullin: a promising profile? Pharmacol. Ther. 103 2004 179 201 (Pubitemid 39302634)
6. G. Cantarella, G. Martinez, V.M. Cutuli, C. Loreto, M. D'Alcamo, A. Prato, M. Amico-Roxas, R. Bernardini, and G. Clementi Adrenomedullin modulates COX-2 and HGF expression in reserpine-injuried gastric mucosa in the rat Eur. J. Pharmacol. 518 2005 221 226 (Pubitemid 41133648)
7. R. Di Paola, E. Talero, M. Galuppo, E. Mazzon, P. Bramanti, V. Motilva, and S. Cuzzocrea Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis Respir. Res. 12 2011 41
8. M.A. Engel, and M.F. Neurath New pathophysiological insights and modern treatment of IBD J. Gastroenterol. 45 2010 571 583
9. E. Gonzalez-Rey, A. Chorny, N. Varela, G. Robledo, and M. Delgado Urocortin and adrenomedullin prevent lethal endotoxemia by down-regulating the inflammatory response Am. J. Pathol. 168 2006 1921 1930 (Pubitemid 43825312)
10. E. Gonzalez-Rey, A. Fernandez-Martin, A. Chorny, and M. Delgado Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease Gut 55 2006 824 832 (Pubitemid 43764553)
11. D.L. Granger, R.R. Taintor, K.S. Boockvar, and J.B. Hibbs Jr. Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction Methods Enzymol. 268 1996 142 151 (Pubitemid 26286356)
12. M.B. Grisham, J.N. Beniot, and D.N. Granger Assessment of leukocyte involvement during ischemia and reperfusion of intestine Methods Enzymol. 186 1990 729 742 (Pubitemid 20280020)
13. O.A. Hatoum, D.G. Binion, M.F. Otterson, and D.D. Gutterman Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation Gastroenterology 125 2003 58 69 (Pubitemid 36799107)
14. O.A. Hatoum, J. Heidemann, and D.G. Binion The intestinal microvasculature as a therapeutic target in inflammatory bowel disease Ann. N. Y. Acad. Sci. 1072 2006 78 97 (Pubitemid 44448445)
15. C.B. Ibrahim, O.C. Aroniadis, and L.J. Brandt On the role of ischemia in the pathogenesis of IBD: a review Inflamm. Bowel Dis. 16 2010 696 702
16. Y. Ichiki, K. Kitamura, K. Kangawa, M. Kawamoto, H. Matsuo, and T. Eto Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma FEBS Lett. 338 1994 6 10 (Pubitemid 24047772)
17. K. Ito, H. Yoshii, T. Asano, K. Seta, Y. Mizuguchi, M. Yamanaka, S. Tokonabe, M. Hayakawa, and T. Asano Adrenomedullin increases renal nitric oxide production and ameliorates renal injury in mice with unilateral ureteral obstruction J. Urol. 183 2010 1630 1635
18. M. Kerem, A. Bedirli, H. Pasaoglu, E. Ofluoǧlu, D. Yilmazer, B. Salman, and T.U. Yilmaz Effect of adrenomedullin on hepatic damage in hepatic ischaemia/reperfusion injury in rats Liver Int. 28 2008 972 981 (Pubitemid 352044445)
19. F. Lamine, J. Fioramonti, L. Bueno, F. Nepveu, E. Cauquil, I. Lobysheva, H. Eutamène, and V. Théodorou Nitric oxide released by Lactobacillus farciminis improves TNBS-induced colitis in rats Scand. J. Gastroenterol. 39 2004 37 45 (Pubitemid 38221712)
20. E.G. Lee, S.I. Lee, H.J. Chae, S.J. Park, Y.C. Lee, and W.H. Yoo Adrenomedullin inhibits IL-1beta-induced rheumatoid synovial fibroblast proliferation and MMPs, COX-2 and PGE2 production Inflammation 34 2011 335 343
21. Y.H. Looi, K.A. Kane, A.R. McPhaden, and C.L. Wainwright Adrenomedullin acts via nitric oxide and peroxynitrite to protect against myocardial ischaemia-induced arrhythmias in anaesthetized rats Br. J. Pharmacol. 148 2006 599 609 (Pubitemid 43996779)
22. J.O. Lundberg Rectal NO and fecal calprotectin in IBD Scand. J. Gastroenterol. 44 2009 128
23. G.P. Morris, P.L. Beck, M.S. Herridge, W.T. Depew, M.R. Szewczuk, and J.L. Wallace Hapten-induced model of chronic inflammation and ulceration in the rat colon Gastroenterology 96 1989 795 803 (Pubitemid 19057602)
24. V. Motilva, E. Talero, J.R. Calvo, I. Villegas, C. Alarcón-de-la- Lastra, and S. Sánchez-Fidalgo Intestinal immunomodulation. Role of regulative peptides and promising pharmacological activities Curr. Pharm. Des. 14 2008 71 95 (Pubitemid 351266986)
25. M.F. Neurath, S. Finotto, and L.H. Glimcher The role of Th1/Th2 polarization in mucosal immunity Nat. Med. 8 2002 567 573 (Pubitemid 34633433)
26. A.P. Paiotti, R. Artigiani Neto, N.M. Forones, C.T. Oshima, S.J. Miszputen, and M. Franco Immunoexpression of cyclooxygenase-1 and -2 in ulcerative colitis Braz. J. Med. Biol. Res. 40 2007 911 918 (Pubitemid 47232875)
27. A. Papa, F. Scaldaferri, S. Danese, S. Guglielmo, I. Roberto, M. Bonizzi, G. Mocci, C. Felice, C. Ricci, G. Andrisani, G. Fedeli, G. Gasbarrini, and A. Gasbarrini Vascular involvement in inflammatory bowel disease: pathogenesis and clinical aspects Dig. Dis. 26 2008 149 155 (Pubitemid 351572140)
28. J. Petersson, O. Schreiber, A. Steege, A. Patzak, A. Hellsten, M. Phillipson, and L. Holm eNOS involved in colitis-induced mucosal blood flow increase Am. J. Physiol. Gastrointest. Liver Physiol. 293 2007 G1281 G1287 (Pubitemid 350255047)
29. I. Roifman, Y.C. Sun, J.P. Fedwick, R. Panaccione, A.G. Buret, H. Liu, A. Rostom, T.J. Anderson, and P.L. Beck Evidence of endothelial dysfunction in patients with inflammatory bowel disease Clin. Gastroenterol. Hepatol. 7 2009 175 182
30. G.R. Ross, and C. Yallampalli Endothelium-independent relaxation by adrenomedullin in pregnant rat mesenteric artery: role of cAMP-dependent protein kinase A and calcium-activated potassium channels J. Pharmacol. Exp. Ther. 317 2006 1269 1275 (Pubitemid 43764133)
31. S. Sánchez-Fidalgo, A. Cárdeno, I. Villegas, E. Talero, and C.A. de la Lastra Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice Eur. J. Pharmacol. 633 2010 78 84
32. A. Tabernero, J.M. Reimund, S. Chasserot, C.D. Muller, and R. Andriantsitohaina Cyclooxygenase-2 expression and role of vasoconstrictor prostanoids in small mesenteric arteries from patients with Crohn's disease Circulation 107 2003 1407 1410 (Pubitemid 36350740)
33. E. Talero, S. Sánchez-Fidalgo, J.R. Calvo, and V. Motilva Chronic administration of galanin attenuates the TNBS-induced colitis in rats Regul. Pept. 141 2007 96 104 (Pubitemid 46482689)
34. E. Talero, S. Sánchez-Fidalgo, C.A. de la Lastra, M. Illanes, J.R. Calvo, and V. Motilva Acute and chronic responses associated with adrenomedullin administration in experimental colitis Peptides 29 2008 2001 2012
35. B. Temmesfeld-Wollbrück, A.C. Hocke, N. Suttorp, and S. Hippenstiel Adrenomedullin and endothelial barrier function Thromb. Haemost. 98 2007 944 951 (Pubitemid 350107695)
36. J.L. Wallace, and M.J. Miller Nitric oxide in mucosal defence: a little goes a long way Gastroenterology 119 2000 512 520 (Pubitemid 30622002)