Evidence of Endothelial Dysfunction in Patients With Inflammatory Bowel Disease

Clinical Gastroenterology and Hepatology

Volumn 7, Issue 2, 2009, Pages 175-182

  Roifman, Idan ^a   Sun, Yichun C ^b   Fedwick, Jason P ^a   Panaccione, Remo ^a   Buret, Andre G ^a   Liu, Hongqun ^a   Rostom, Alaa ^a   Anderson, Todd J ^b   Beck, Paul L ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 ACETAMIDOSALICYLIC ACID; AZATHIOPRINE; CORTICOSTEROID; INFLIXIMAB; MESALAZINE;

ABDOMINAL PAIN; ADULT; ANEMIA; ARTERY BLOOD FLOW; ARTERY DIAMETER; ARTICLE; BLOOD FLOW VELOCITY; BRACHIAL ARTERY; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DEMOGRAPHY; DISEASE ACTIVITY; DISEASE DURATION; ENDOTHELIAL DYSFUNCTION; ENTERITIS; FEMALE; HUMAN; HYPEREMIA; LEUKOCYTOSIS; MALE; MICROVASCULATURE; PLETHYSMOGRAPHY; PULSE WAVE; RECTUM HEMORRHAGE; SCORING SYSTEM; SHEAR STRESS; THROMBOCYTOSIS; TONOMETRY; ULCERATIVE COLITIS;

ADULT; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MANOMETRY; PERIPHERAL VASCULAR DISEASES; SEVERITY OF ILLNESS INDEX; ULTRASONOGRAPHY, INTERVENTIONAL;

EID: 58849127465     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2008.10.021     Document Type: Article

References (66)

1. Danese S. Inflammation and the mucosal microcirculation in inflammatory bowel disease: the ebb and flow. Curr Opin Gastroenterol 23 (2007) 384-389
2. Huerta C., Johansson S., Wallander M.A., et al. Risk factors and short-term mortality of venous thromboembolism diagnosed in the primary care setting in the United Kingdom. Arch Intern Med 167 (2007) 935-943
3. Chidlow Jr. J.H., Shukla D., Grisham M.B., et al. Pathogenic angiogenesis in IBD and experimental colitis: new ideas and therapeutic avenues. Am J Physiol 293 (2007) G5-G18
4. Danese S., Scaldaferri F., Vetrano S., et al. Critical role of the CD40 CD40-ligand pathway in regulating mucosal inflammation-driven angiogenesis in inflammatory bowel disease. Gut 56 (2007) 1248-1256
5. Hatoum O.A., Miura H., and Binion D.G. The vascular contribution in the pathogenesis of inflammatory bowel disease. Am J Physiol Heart Circ Physiol 285 (2003) H1791-H1796
6. Bernstein C.N., Wajda A., and Blanchard J.F. The incidence of arterial thromboembolic diseases in inflammatory bowel disease: a population-based study. Clin Gastroenterol Hepatol 6 (2008) 41-45
7. Zurawski J., Wozniak A., Salwa-Zurawska W., et al. Vascular changes in ulcerative colitis and Lesniowski-Crohn's disease. Pol J Pathol 58 (2007) 13-21
8. Scaldaferri F., Sans M., Vetrano S., et al. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J Clin Invest 117 (2007) 1951-1960
9. Wakefield A.J., Sankey E.A., Dhillon A.P., et al. Granulomatous vasculitis in Crohn's disease. Gastroenterology 100 (1991) 1279-1287
10. Danese S., Sans M., Scaldaferri F., et al. TNF-alpha blockade down-regulates the CD40/CD40L pathway in the mucosal microcirculation: a novel anti-inflammatory mechanism of infliximab in Crohn's disease. J Immunol 176 (2006) 2617-2624
11. Peyrin-Biroulet L., Rodriguez-Gueant R.M., Chamaillard M., et al. Vascular and cellular stress in inflammatory bowel disease: revisiting the role of homocysteine. Am J Gastroenterol 102 (2007) 1108-1115
12. Hatoum O.A., Heidemann J., and Binion D.G. The intestinal microvasculature as a therapeutic target in inflammatory bowel disease. Ann N Y Acad Sci 1072 (2006) 78-97
13. Gulubova M.V., Manolova I.M., Vlaykova T.I., et al. Adhesion molecules in chronic ulcerative colitis. Int J Colorectal Dis 22 (2007) 581-589
14. Kullo I.J., Seward J.B., Bailey K.R., et al. C-reactive protein is related to arterial wave reflection and stiffness in asymptomatic subjects from the community. Am J Hypertens 18 (2005) 1123-1129
15. Kathiresan S., Larson M.G., Vasan R.S., et al. Common genetic variation at the endothelial nitric oxide synthase locus and relations to brachial artery vasodilator function in the community. Circulation 112 (2005) 1419-1427
16. Vita J.A., Keaney Jr. J.F., Larson M.G., et al. Brachial artery vasodilator function and systemic inflammation in the Framingham Offspring Study. Circulation 110 (2004) 3604-3609
17. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362 (1993) 801-809
18. Anderson T.J. Nitric oxide, atherosclerosis and the clinical relevance of endothelial dysfunction. Heart Fail Rev 8 (2003) 71-86
19. Anderson T.J. Assessment and treatment of endothelial dysfunction in humans. J Am Coll Cardiol 34 (1999) 631-638
20. Zebrack J.S., Muhlestein J.B., Horne B.D., et al. C-reactive protein and angiographic coronary artery disease: independent and additive predictors of risk in subjects with angina. J Am Coll Cardiol 39 (2002) 632-637
21. Pyke K.E., and Tschakovsky M.E. The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol 568 (2005) 357-369
22. Lee M.Y., Chu C.S., Lee K.T., et al. Reactive hyperemic pre-ejection shear stress of brachial artery determines endothelial function in patients with untreated essential hypertension. Int J Cardiol 122 (2007) 68-71
23. Wright S.A., O'Prey F.M., Rea D.J., et al. Microcirculatory hemodynamics and endothelial dysfunction in systemic lupus erythematosus. Arterioscler Thromb Vasc Biol 26 (2006) 2281-2287
24. Mitchell G.F., Parise H., Vita J.A., et al. Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study. Hypertension 44 (2004) 134-139
25. Irace C., Cortese C., Fiaschi E., et al. Wall shear stress is associated with intima-media thickness and carotid atherosclerosis in subjects at low coronary heart disease risk. Stroke 35 (2004) 464-468
26. Irace C., Carallo C., Crescenzo A., et al. NIDDM is associated with lower wall shear stress of the common carotid artery. Diabetes 48 (1999) 193-197
27. Gnasso A., Irace C., Carallo C., et al. In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis. Stroke 28 (1997) 993-998
28. Irace C., Tamburrini S., Bertucci B., et al. Effects of iodinated contrast media on common carotid and brachial artery blood flow and wall shear stress. Eur Radiol 16 (2006) 2721-2727
29. Bonetti P.O., Pumper G.M., Higano S.T., et al. Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J Am Coll Cardiol 44 (2004) 2137-2141
30. Kuvin J.T., Mammen A., Mooney P., et al. Assessment of peripheral vascular endothelial function in the ambulatory setting. Vasc Med 12 (2007) 13-16
31. Anderson T.J., Uehata A., Gerhard M.D., et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 26 (1995) 1235-1241
32. Anderson T.J., Elstein E., Haber H., et al. Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study). J Am Coll Cardiol 35 (2000) 60-66
33. Beckman J.A., Liao J.K., Hurley S., et al. Atorvastatin restores endothelial function in normocholesterolemic smokers independent of changes in low-density lipoprotein. Circ Res 95 (2004) 217-223
34. Kathiresan S., Gona P., Larson M.G., et al. Cross-sectional relations of multiple biomarkers from distinct biological pathways to brachial artery endothelial function. Circulation 113 (2006) 938-945
35. Corretti M.C., Anderson T.J., Benjamin E.J., et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39 (2002) 257-265
36. Bacon P.A., Stevens R.J., Carruthers D.M., et al. Accelerated atherogenesis in autoimmune rheumatic diseases. Autoimmun Rev 1 (2002) 338-347
37. Abou-Raya A., and Abou-Raya S. Inflammation: a pivotal link between autoimmune diseases and atherosclerosis. Autoimmun Rev 5 (2006) 331-337
38. Shepshelovich D., Sherer Y., and Shoenfeld Y. [Accelerated atherosclerosis in rheumatoid arthritis]. Harefuah 144 (2005) 561-563 98
39. Seriolo B., Sulli A., Burroni A., et al. [Rheumatoid arthritis and atherosclerosis]. Reumatismo 55 (2003) 140-146
40. Doria A., Sherer Y., Meroni P.L., et al. Inflammation and accelerated atherosclerosis: basic mechanisms. Rheum Dis Clin North Am 31 (2005) 355-362 viii
41. Murtagh B.M., and Anderson H.V. Inflammation and atherosclerosis in acute coronary syndromes. J Invasive Cardiol 16 (2004) 377-384
42. Verma S., Wang C.H., Lonn E., et al. Cross-sectional evaluation of brachial artery flow-mediated vasodilation and C-reactive protein in healthy individuals. Eur Heart J 25 (2004) 1754-1760
43. Vita J.A., Brennan M.L., Gokce N., et al. Serum myeloperoxidase levels independently predict endothelial dysfunction in humans. Circulation 110 (2004) 1134-1139
44. Walmsley R.S., Ayres R.C., Pounder R.E., et al. A simple clinical colitis activity index. Gut 43 (1998) 29-32
45. Graff L.A., Walker J.R., Lix L., et al. The relationship of inflammatory bowel disease type and activity to psychological functioning and quality of life. Clin Gastroenterol Hepatol 4 (2006) 1491-1501
46. Hatoum O.A., Spinelli K.S., Abu-Hajir M., et al. Mesenteric venous thrombosis in inflammatory bowel disease. J Clin Gastroenterol 39 (2005) 27-31
47. Funayama Y., Sasaki I., Imamura M., et al. [The analyses of intestinal microcirculation by histometrical studies of arterial media in Crohn's disease]. Nippon Geka Gakkai Zasshi 88 (1987) 1695-1704
48. Taylor C.T., and Colgan S.P. Hypoxia and gastrointestinal disease. J Mol Med 85 (2007) 1295-1300
49. Maconi G., Imbesi V., and Bianchi Porro G. Doppler ultrasound measurement of intestinal blood flow in inflammatory bowel disease. Scand J Gastroenterol 31 (1996) 590-593
50. Giatromanolaki A., Sivridis E., Maltezos E., et al. Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease. J Clin Pathol 56 (2003) 209-213
51. Bolondi L., Gaiani S., Brignola C., et al. Changes in splanchnic hemodynamics in inflammatory bowel disease. Non-invasive assessment by Doppler ultrasound flowmetry. Scand J Gastroenterol 27 (1992) 501-507
52. Mori M., Stokes K.Y., Vowinkel T., et al. Colonic blood flow responses in experimental colitis: time course and underlying mechanisms. Am J Physiol 289 (2005) G1024-G1029
53. Homann N., Klarmann U., Fellermann K., et al. Mesenteric pulsatility index analysis predicts response to azathioprine in patients with Crohn's disease. Inflamm Bowel Dis 11 (2005) 126-132
54. Palatka K., Serfozo Z., Vereb Z., et al. Effect of IBD sera on expression of inducible and endothelial nitric oxide synthase in human umbilical vein endothelial cells. World J Gastroenterol 12 (2006) 1730-1738
55. Hatoum O.A., Gauthier K.M., Binion D.G., et al. Novel mechanism of vasodilation in inflammatory bowel disease. Arterioscler Thromb Vasc Biol 25 (2005) 2355-2361
56. Hatoum O.A., Binion D.G., Otterson M.F., et al. Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation. Gastroenterology 125 (2003) 58-69
57. Schinzari F., Armuzzi A., De Pascalis B., et al. Tumor necrosis factor-alpha antagonism improves endothelial dysfunction in patients with Crohn's disease. Clin Pharmacol Ther 83 (2008) 70-76
58. Hurlimann D., Forster A., Noll G., et al. Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis. Circulation 106 (2002) 2184-2187
59. Celermajer D.S., Sorensen K.E., Bull C., et al. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J Am Coll Cardiol 24 (1994) 1468-1474
60. Dorn S.D., and Sandler R.S. Inflammatory bowel disease is not a risk factor for cardiovascular disease mortality: results from a systematic review and meta-analysis. Am J Gastroenterol 102 (2007) 662-667
61. Papa A., Danese S., Urgesi R., et al. Early atherosclerosis in patients with inflammatory bowel disease. Eur Rev Med Pharmacol Sci 10 (2006) 7-11
62. Papa A., Santoliquido A., Danese S., et al. Increased carotid intima-media thickness in patients with inflammatory bowel disease. Aliment Pharmacol Ther 22 (2005) 839-846
63. Levy P.J., Tabares A.H., and Olin J.W. Lower extremity arterial occlusions in young patients with Crohn's colitis and premature atherosclerosis: report of six cases. Am J Gastroenterol 92 (1997) 494-497
64. Maharshak N., Arbel Y., Bornstein N.M., et al. Inflammatory bowel disease is not associated with increased intimal media thickening. Am J Gastroenterol 102 (2007) 1050-1055
65. Andre P., Nannizzi-Alaimo L., Prasad S.K., et al. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation 106 (2002) 896-899
66. Danese S., de la Motte C., Sturm A., et al. Platelets trigger a CD40-dependent inflammatory response in the microvasculature of inflammatory bowel disease patients. Gastroenterology 124 (2003) 1249-1264