Fish oil combined with SCFA synergistically prevent tissue accumulation of NEFA during weight loss in obese mice

British Journal of Nutrition

Volumn 106, Issue 10, 2011, Pages 1449-1456

  Pedersen, Maiken H ^a,b   Lauritzen, Lotte ^b   Hellgren, Lars I ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Acetate; Fish oil; SCFA; Tissue NEFA; Weight loss

Indexed keywords

FATTY ACID; FISH OIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INSULIN RECEPTOR; LARD; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLASMINOGEN ACTIVATOR INHIBITOR 1; RESISTIN; SAFFLOWER OIL; SALATRIM; SHORT CHAIN FATTY ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CALORIC INTAKE; CONTROLLED STUDY; DIETARY INTAKE; FATTY ACID BLOOD LEVEL; HEART; INSULIN BLOOD LEVEL; LIPID COMPOSITION; LIPID LIVER LEVEL; LOW FAT DIET; MALE; MOUSE; NONHUMAN; OBESITY; TISSUE LEVEL; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE;

CARTHAMUS TINCTORIUS; MUS;

EID: 80755185126     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511001917     Document Type: Article

References (41)

1. Thorsdottir I, Tomasson H, Gunnarsdottir I, et al. (2007) Randomized trial of weight-loss-diets for young adults varying in fish and fish oil content. Int J Obes 31, 1560-1566. (Pubitemid 47482660)
2. Hill AM, Buckley JD, Murphy KJ, et al. (2007) Combining fish-oil supplements with regular aerobic exercise improves body composition and cardiovascular disease risk factors. Am J Clin Nutr 85, 1267-1274. (Pubitemid 46740468)
3. Kunesova M, Braunerova R, Hlavaty P, et al. (2006) The influence of n-3 polyunsaturated fatty acids and very low calorie diet during a short-term weight reducing regimen on weight loss and serum fatty acid composition in severely obese women. Physiol Res 55, 63-72. (Pubitemid 43276813)
4. Sjoholm A & Nystrom T (2006) Inflammation and the etiology of type 2 diabetes. Diabetes Metab Res Rev 22, 4-10. (Pubitemid 43154455)
5. Kanda H, Tateya S, Tamori Y, et al. (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116, 1494-1505.
6. Lee YH, Nair S, Rousseau E, et al. (2005) Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes. Diabetologia 48, 1776-1783. (Pubitemid 41317831)
7. Curat CA, Miranville A, Sengenes C, et al. (2004) From blood monocytes to adipose tissue-residentmacrophages-induction of diapedesis by human mature adipocytes. Diabetes 53, 1285-1292. (Pubitemid 38569015)
8. Fain JN (2006) Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Interleukins 74, 443-477.
9. Nieto-Vazquez I, Fernandez-Veledo S, Kraemer DK, et al. (2008) Insulin resistance associated to obesity: the link TNF-alpha. Arch Physiol Biochem 114, 183-194. (Pubitemid 352009305)
10. de Alvaro C, Teruel T, Hernandez R, et al. (2004) Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappa B kinase in a p38 MAPK-dependent manner. J Biol Chem 279, 17070-17078. (Pubitemid 38560462)
11. Feinstein R, Kanety H, Papa MZ, et al. (1993) Tumornecrosis-factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin-receptor and its substrates. J Biol Chem 268, 26055-26058.
12. Boden G (2002) Interaction between free fatty acids and glucose metabolism. Curr Opin Clin Nutr Metab Care 5, 545-549. (Pubitemid 40684651)
13. Todoric J, Loffler M, Huber J, et al. (2006) Adipose tissue inflammation induced by high-fat diet in obese diabetic mice is prevented by n-3 polyunsaturated fatty acids. Diabetologia 49, 2109-2119. (Pubitemid 44168479)
14. Krebs JD, Browning LM, Mclean NK, et al. (2006) Additive benefits of long-chain n-3 polyunsaturated fatty acids and weight-loss in the management of cardiovascular disease risk in overweight hyperinsulinaemic women. Int J Obes 30, 1535-1544. (Pubitemid 44470203)
15. Jiang CY, Ting AT & Seed B (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391, 82-86. (Pubitemid 28079219)
16. Guri AJ, Hontecillas R & Bassaganya-Riera J (2006) Peroxisome proliferator-activated receptors: bridging metabolic syndrome with molecular nutrition. Clin Nutr 25, 871-885. (Pubitemid 44743162)
17. Jump DB, Botolin D, Wang Y, et al. (2005) Fatty acid regulation of hepatic gene transcription. J Nutr 135, 2503-2506. (Pubitemid 43156586)
18. Finley JW, Klemann LP, Leveille GA, et al. (1994) Caloric availability of salatrim in rats and humans. J Agric Food Chem 42, 495-499.
19. Zapolska-Downar D, Siennicka A, Kaczmarczyk M, et al. (2004) Butyrate inhibits cytokine-induced VCAM-1 and ICAM-1 expression in cultured endothelial cells: the role of NF-kappa B and PPAR alpha. J Nutr Biochem 15, 220-228. (Pubitemid 38447260)
20. Maslowski KM, Vieira AT, Ng A, et al. (2009) Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 461, 1282-1286.
21. Covington DK, Briscoe CA, Brown AJ, et al. (2006) The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing. Biochem Soc Trans 34, 770-773. (Pubitemid 44796417)
22. Tiwari A (2010) GPR43: an emerging target for the potential treatment of type 2 diabetes, obesity and insulin resistance. Curr Opin Investig Drugs 11, 385-393.
23. Folch J, Lees M & Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226, 497-509.
24. Artmann A, Petersen G, Hellgren LI, et al. (2008) Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine. Biochim Biophys Acta 1781, 200-212.
25. Artmann A, Petersen G, Hellgren LI, et al. (2008) Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine. Biochim Biophys Acta 1781, 200-212.
26. Mori TA, Bao DQ, Burke V, et al. (1999) Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects. Am J Clin Nutr 70, 817-825. (Pubitemid 29512906)
27. Abete I, Parra D, Crujeiras AB, et al. (2008) Specific insulin sensitivity and leptin responses to a nutritional treatment of obesity via a combination of energy restriction and fatty fish intake. J Hum Nutr Diet 21, 591-600.
28. Nakatani T, Kim HJ, Kaburagi Y, et al. (2003) A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver: relationship to anti-obesity. J Lipid Res 44, 369-379. (Pubitemid 37287780)
29. Ikemoto S, Takahashi M, Tsunoda N, et al. (1996) High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils. Metabolism 45, 1539-1546. (Pubitemid 26424584)
30. Hassanali Z, Ametaj BN, Field CJ, et al. (2010) Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat. Diabetes Obes Metab 12, 139-147.
31. Arai T, Kim HJ, Chiba H, et al. (2009) Anti-obesity effect of fish oil and fish oil-fenofibrate combination in female KK mice. J Atheroscler Thromb 16, 674-683.
32. Mori T, Kondo H, Hase T, et al. (2007) Dietary fish oil upregulates intestinal lipid metabolism and reduces body weight gain in C57BL/6J mice. J Nutr 137, 2629-2634. (Pubitemid 350255289)
33. Storlien LH, Kraegen EW, Chisholm DJ, et al. (1987) Fish oil prevents insulin resistance induced by high-fat feeding in rats. Science 237, 885-888. (Pubitemid 17128276)
34. Neschen S, Morino K, Dong JY, et al. (2007) N-3 fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner. Diabetes 56, 1034-1041. (Pubitemid 46525082)
35. JuckerBM, ClineGW, Barucci N, et al. (1999) Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle-a C-13 nuclear magnetic resonance study. Diabetes 48, 134-140. (Pubitemid 29019364)
36. Ramel A, Martinez A, Kiely M, et al. (2008) Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults. Diabetologia 51, 1261-1268.
37. Trauner M, Arrese M & Wagner M (2010) Fatty liver and lipotoxicity. Biochim Biophys Acta 1801, 299-310.
38. Szczepaniak LS, Victor RG, Orci L, et al. (2007) Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res 101, 759-767. (Pubitemid 350287190)
39. Cummings JH, Pomare EW, Branch WJ, et al. (1987) Short chain fatty-acids in human large-intestine, portal, hepatic and venous-blood. Gut 28, 1221-1227. (Pubitemid 17156038)
40. Yin L, Laevsky G & Giardina C (2001) Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. J Biol Chem 276, 44641-44646.
41. Ge HF, Li XF, Weiszmann J, et al. (2008) Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology 149, 4519-4526.