-
1
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways
-
DOI 10.1074/jbc.M706762200
-
Nguyen MT, Favelyukis S, Nguyen AK, et al. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 2007;282:35279-35292 (Pubitemid 350232441)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35279-35292
-
-
Nguyen, M.T.A.1
Favelyukis, S.2
Nguyen, A.-K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
2
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
DOI 10.1038/nm1185
-
Arkan MC, Hevener AL, Greten FR, et al. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med 2005;11:191-198 (Pubitemid 40321355)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.-W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
3
-
-
77952083245
-
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice
-
Li P, Lu M, Nguyen MT, et al. Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem 2010;285:15333-15345
-
(2010)
J Biol Chem
, vol.285
, pp. 15333-15345
-
-
Li, P.1
Lu, M.2
Nguyen, M.T.3
-
4
-
-
34249907880
-
Macrophage PPARgamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
DOI 10.1172/JCI31561
-
Hevener AL, Olefsky JM, Reichart D, et al. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest 2007;117:1658-1669 (Pubitemid 46871350)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
Nguyen, M.T.A.4
Bandyopadyhay, G.5
Leung, H.-Y.6
Watt, M.J.7
Benner, C.8
Febbraio, M.A.9
Nguyen, A.-K.10
Folian, B.11
Subramaniam, S.12
Gonzalez, F.J.13
Glass, C.K.14
Ricote, M.15
-
5
-
-
77649144555
-
Pioglitazone: Side effect and safety profile
-
Shah P, Mudaliar S. Pioglitazone: side effect and safety profile. Expert Opin Drug Saf 2010;9:347-354
-
(2010)
Expert Opin Drug Saf
, vol.9
, pp. 347-354
-
-
Shah, P.1
Mudaliar, S.2
-
6
-
-
46349088791
-
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
-
DOI 10.1210/en.2008-0262
-
Weisberg SP, Leibel R, Tortoriello DV. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 2008;149:3549-3558 (Pubitemid 351919581)
-
(2008)
Endocrinology
, vol.149
, Issue.7
, pp. 3549-3558
-
-
Weisberg, S.P.1
Leibel, R.2
Tortoriello, D.V.3
-
8
-
-
34248385769
-
Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine
-
DOI 10.1007/s00280-006-0355-x
-
Marczylo TH, Verschoyle RD, Cooke DN, Morazzoni P, Steward WP, Gescher AJ. Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine. Cancer Chemother Pharmacol 2007;60:171-177 (Pubitemid 46742531)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, Issue.2
, pp. 171-177
-
-
Marczylo, T.H.1
Verschoyle, R.D.2
Cooke, D.N.3
Morazzoni, P.4
Steward, W.P.5
Gescher, A.J.6
-
9
-
-
57849106304
-
An in vitro study of liposomal curcumin: Stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells
-
Chen C, Johnston TD, Jeon H, et al. An in vitro study of liposomal curcumin: stability, toxicity and biological activity in human lymphocytes and Epstein-Barr virus-transformed human B-cells. Int J Pharm 2009;366:133-139
-
(2009)
Int J Pharm
, vol.366
, pp. 133-139
-
-
Chen, C.1
Johnston, T.D.2
Jeon, H.3
-
10
-
-
65449183747
-
Antigen-specific suppression of inflammatory arthritis using liposomes
-
Capini C, Jaturanpinyo M, Chang HI, et al. Antigen-specific suppression of inflammatory arthritis using liposomes. J Immunol 2009;182:3556-3565
-
(2009)
J Immunol
, vol.182
, pp. 3556-3565
-
-
Capini, C.1
Jaturanpinyo, M.2
Chang, H.I.3
-
11
-
-
0021146385
-
In vitro determination of phagocyte activity by luminol- and lucigenin-amplified chemiluminescence
-
DOI 10.1016/0192-0561(84)90084-5
-
Müller-Peddinghaus R. In vitro determination of phagocyte activity by luminol- and lucigenin-amplified chemiluminescence. Int J Immunopharmacol 1984;6:455-466 (Pubitemid 14031886)
-
(1984)
International Journal of Immunopharmacology
, vol.6
, Issue.5
, pp. 455-466
-
-
Muller-Peddinghaus, R.1
-
12
-
-
77953728203
-
High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay
-
Bhattacharya N, Sarno A, Idler IS, et al. High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay. Int J Cancer 2010;127:404-411
-
(2010)
Int J Cancer
, vol.127
, pp. 404-411
-
-
Bhattacharya, N.1
Sarno, A.2
Idler, I.S.3
-
13
-
-
77958124602
-
Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling
-
Bosschaerts T, Guilliams M, Stijlemans B, et al. Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling. PLoS Pathog 2010;6:e1001045
-
(2010)
PLoS Pathog
, vol.6
-
-
Bosschaerts, T.1
Guilliams, M.2
Stijlemans, B.3
-
14
-
-
0032742418
-
The disease burden associated with overweight and obesity
-
DOI 10.1001/jama.282.16.1523
-
Must A, Spadano J, Coakley EH, Field AE, Colditz G, Dietz WH. The disease burden associated with overweight and obesity. JAMA 1999;282:1523-1529 (Pubitemid 29504045)
-
(1999)
Journal of the American Medical Association
, vol.282
, Issue.16
, pp. 1523-1529
-
-
Must, A.1
Spadano, J.2
Coakley, E.H.3
Field, A.E.4
Colditz, G.5
Dietz, W.H.6
-
15
-
-
0142057121
-
Obesity and health-related quality of life: A cross-sectional analysis of the US population
-
DOI 10.1038/sj.ijo.0802396
-
Hassan MK, Joshi AV, Madhavan SS, Amonkar MM. Obesity and health-related quality of life: a cross-sectional analysis of the US population. Int J Obes Relat Metab Disord 2003;27:1227-1232 (Pubitemid 37281671)
-
(2003)
International Journal of Obesity
, vol.27
, Issue.10
, pp. 1227-1232
-
-
Hassan, M.K.1
Joshi, A.V.2
Madhavan, S.S.3
Amonkar, M.M.4
-
16
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-1808 (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
17
-
-
52749092267
-
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
-
Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 2008;8:301-309
-
(2008)
Cell Metab
, vol.8
, pp. 301-309
-
-
Patsouris, D.1
Li, P.P.2
Thapar, D.3
Chapman, J.4
Olefsky, J.M.5
Neels, J.G.6
-
18
-
-
77956335194
-
Interleukin-6 signaling in liverparenchymal cells suppresses hepatic inflammation and improves systemic insulin action
-
Wunderlich FT, Ströhle P, Könner AC, et al. Interleukin-6 signaling in liverparenchymal cells suppresses hepatic inflammation and improves systemic insulin action. Cell Metab 2010;12:237-249
-
(2010)
Cell Metab
, vol.12
, pp. 237-249
-
-
Wunderlich, F.T.1
Ströhle, P.2
Könner, A.C.3
-
19
-
-
44749093175
-
Curcumin: From ancient medicine to current clinical trials
-
Hatcher H, Planalp R, Cho J, Torti FM, Torti SV. Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci 2008;65:1631-1652
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 1631-1652
-
-
Hatcher, H.1
Planalp, R.2
Cho, J.3
Torti, F.M.4
Torti, S.V.5
-
21
-
-
2442607612
-
Curcumin (Diferuloylmethane) Inhibits Receptor Activator of NF-κB Ligand-Induced NF-κB Activation in Osteoclast Precursors and Suppresses Osteoclastogenesis
-
Bharti AC, Takada Y, Aggarwal BB. Curcumin (diferuloylmethane) inhibits receptor activator of NF-kappa B ligand-induced NF-kappa B activation in osteoclast precursors and suppresses osteoclastogenesis. J Immunol 2004;172:5940-5947 (Pubitemid 38621193)
-
(2004)
Journal of Immunology
, vol.172
, Issue.10
, pp. 5940-5947
-
-
Bharti, A.C.1
Takada, Y.2
Aggarwal, B.B.3
-
22
-
-
34248573808
-
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products
-
DOI 10.1158/0008-5472.CAN-06-4257
-
Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, Aggarwal BB. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products. Cancer Res 2007;67:3853-3861 (Pubitemid 46762173)
-
(2007)
Cancer Research
, vol.67
, Issue.8
, pp. 3853-3861
-
-
Kunnumakkara, A.B.1
Guha, S.2
Krishnan, S.3
Diagaradjane, P.4
Gelovani, J.5
Aggarwal, B.B.6
-
23
-
-
33947373996
-
Suppression of NF-κB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis
-
DOI 10.1016/j.bcp.2007.01.005, PII S0006295207000147
-
Shakibaei M, John T, Schulze-Tanzil G, Lehmann I, Mobasheri A. Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: implications for the treatment of osteoarthritis. Biochem Pharmacol 2007;73:1434-1445 (Pubitemid 46452591)
-
(2007)
Biochemical Pharmacology
, vol.73
, Issue.9
, pp. 1434-1445
-
-
Shakibaei, M.1
John, T.2
Schulze-Tanzil, G.3
Lehmann, I.4
Mobasheri, A.5
-
24
-
-
58149090424
-
Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats
-
Jain SK, Rains J, Croad J, Larson B, Jones K. Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats. Antioxid Redox Signal 2009;11:241-249
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 241-249
-
-
Jain, S.K.1
Rains, J.2
Croad, J.3
Larson, B.4
Jones, K.5
-
25
-
-
0001513966
-
Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
-
DOI 10.1073/pnas.94.6.2557
-
Yang SQ, Lin HZ, Lane MD, Clemens M, Diehl AM. Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis. Proc Natl Acad Sci USA 1997;94:2557-2562 (Pubitemid 27136914)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.6
, pp. 2557-2562
-
-
Yang, S.Q.1
Lin, H.Z.2
Lane, M.D.3
Clemens, M.4
Diehl, A.M.5
-
26
-
-
0036894480
-
NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States
-
Marrero JA, Fontana RJ, Su GL, Conjeevaram HS, Emick DM, Lok AS. NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States. Hepatology 2002;36:1349-1354
-
(2002)
Hepatology
, vol.36
, pp. 1349-1354
-
-
Marrero, J.A.1
Fontana, R.J.2
Su, G.L.3
Conjeevaram, H.S.4
Emick, D.M.5
Lok, A.S.6
-
27
-
-
34347354309
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, et al. Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Nature 2007;447:1116-1120 (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
28
-
-
44349161098
-
Alternative M2 Activation of Kupffer Cells by PPARdelta Ameliorates Obesity-Induced Insulin Resistance
-
DOI 10.1016/j.cmet.2008.04.003, PII S1550413108001137
-
Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, et al. Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab 2008;7:496-507 (Pubitemid 351729205)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red, E.A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
29
-
-
77952562218
-
Natural killer T cells within the liver: Conductors of the hepatic immune orchestra
-
Swain MG. Natural killer T cells within the liver: conductors of the hepatic immune orchestra. Dig Dis 2010;28:7-13
-
(2010)
Dig Dis
, vol.28
, pp. 7-13
-
-
Swain, M.G.1
-
30
-
-
10044286529
-
Going both ways: Immune regulation via CD1d-dependent NKT cells
-
DOI 10.1172/JCI200423594
-
Godfrey DI, Kronenberg M. Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest 2004;114:1379-1388 (Pubitemid 40385565)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.10
, pp. 1379-1388
-
-
Godfrey, D.I.1
Kronenberg, M.2
-
32
-
-
33745486749
-
CD4+CD25+ Tregs and NKT cells: Regulators regulating regulators
-
La Cava A, Van Kaer L, Fu-Dong-Shi. CD4+CD25+ Tregs and NKT cells: regulators regulating regulators. Trends Immunol 2006;27:322-327
-
(2006)
Trends Immunol
, vol.27
, pp. 322-327
-
-
La Cava, A.1
Van Kaer, L.2
Fu, D.-S.3
-
33
-
-
0034005303
-
Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: Potential mechanism for sensitization to liver damage
-
Guebre-Xabier M, Yang S, Lin HZ, Schwenk R, Krzych U, Diehl AM. Altered hepatic lymphocyte subpopulations in obesity-related murine fatty livers: potential mechanism for sensitization to liver damage. Hepatology 2000;31:633-640 (Pubitemid 30118631)
-
(2000)
Hepatology
, vol.31
, Issue.3
, pp. 633-640
-
-
Guebre-Xabier, M.1
Yang, S.2
Lin, H.Z.3
Schwenk, R.4
Krzych, U.5
Diehl, A.M.6
-
34
-
-
33646016323
-
Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping
-
Elinav E, Pappo O, Sklair-Levy M, et al. Adoptive transfer of regulatory NKT lymphocytes ameliorates non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice and is associated with intrahepatic CD8 trapping. J Pathol 2006;209:121-128
-
(2006)
J Pathol
, vol.209
, pp. 121-128
-
-
Elinav, E.1
Pappo, O.2
Sklair-Levy, M.3
-
35
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009;15:930-939
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
-
36
-
-
77953110535
-
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
-
Ilan Y, Maron R, Tukpah AM, et al. Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice. Proc Natl Acad Sci USA 2010;107:9765-9770
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 9765-9770
-
-
Ilan, Y.1
Maron, R.2
Tukpah, A.M.3
|