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Volumn 13, Issue 6, 2011, Pages

Epigenetics in breast cancer: What's new?

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; BENZAMIDE; BISULFITE; DNA GLYCOSYLTRANSFERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ENTINOSTAT; HISTONE; HISTONE DEACETYLASE; HISTONE METHYLTRANSFERASE; HYDROGEN PEROXIDE; HYDROXAMIC ACID; LYSINE; LYSINE SPECIFIC DEMETHYLASE 1; METHYLTRANSFERASE; PARGYLINE; RESTRICTION ENDONUCLEASE; ROMIDEPSIN; SHORT CHAIN FATTY ACID; TETRAPEPTIDE; TRANSCRIPTION FACTOR EZH2; TRANYLCYPROMINE; UNCLASSIFIED DRUG; VORINOSTAT;

EID: 80755173292     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr2925     Document Type: Review
Times cited : (109)

References (82)
  • 1
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • 10.1126/science.1063127, 11498575
    • Jenuwein T, Allis CD. Translating the histone code. Science 2001, 293:1074-1080. 10.1126/science.1063127, 11498575.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 2
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • 10.1016/j.cell.2007.01.029, 17320506
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007, 128:683-692. 10.1016/j.cell.2007.01.029, 17320506.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 3
    • 36849037857 scopus 로고    scopus 로고
    • Epigenetic regulation as a new target for breast cancer therapy
    • 10.1080/07357900701719234, 18058459
    • Stearns V, Zhou Q, Davidson NE. Epigenetic regulation as a new target for breast cancer therapy. Cancer Invest 2007, 25:659-665. 10.1080/07357900701719234, 18058459.
    • (2007) Cancer Invest , vol.25 , pp. 659-665
    • Stearns, V.1    Zhou, Q.2    Davidson, N.E.3
  • 4
    • 30344477367 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
    • 10.1038/nrc1779, 16397526
    • Minucci S, Pelicci PG. Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nat Rev Cancer 2006, 6:38-51. 10.1038/nrc1779, 16397526.
    • (2006) Nat Rev Cancer , vol.6 , pp. 38-51
    • Minucci, S.1    Pelicci, P.G.2
  • 5
    • 26444439216 scopus 로고    scopus 로고
    • Prospects: histone deacetylase inhibitors
    • 10.1002/jcb.20532, 16088937
    • Dokmanovic M, Marks PA. Prospects: histone deacetylase inhibitors. J Cell Biochem 2005, 96:293-304. 10.1002/jcb.20532, 16088937.
    • (2005) J Cell Biochem , vol.96 , pp. 293-304
    • Dokmanovic, M.1    Marks, P.A.2
  • 7
    • 65449166411 scopus 로고    scopus 로고
    • Novel structural insights into class I and II histone deacetylases
    • 10.2174/156802609788085304, 19355988
    • Ficner R. Novel structural insights into class I and II histone deacetylases. Curr Top Med Chem 2009, 9:235-240. 10.2174/156802609788085304, 19355988.
    • (2009) Curr Top Med Chem , vol.9 , pp. 235-240
    • Ficner, R.1
  • 8
    • 70349128205 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: design, structure-activity relationships and therapeutic implications for cancer
    • Marson CM. Histone deacetylase inhibitors: design, structure-activity relationships and therapeutic implications for cancer. Anticancer Agents Med Chem 2009, 9:661-692.
    • (2009) Anticancer Agents Med Chem , vol.9 , pp. 661-692
    • Marson, C.M.1
  • 9
    • 57049120498 scopus 로고    scopus 로고
    • Drug Insight: histone deacetylase inhibitor-based therapies for cutaneous T-cell lymphomas
    • 10.1038/ncponc1238, 18839006
    • Khan O, La Thangue NB. Drug Insight: histone deacetylase inhibitor-based therapies for cutaneous T-cell lymphomas. Nat Clin Pract Oncol 2008, 5:714-726. 10.1038/ncponc1238, 18839006.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 714-726
    • Khan, O.1    La Thangue, N.B.2
  • 10
    • 0242330341 scopus 로고    scopus 로고
    • A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine
    • 10.1023/A:1026146524737, 14620913
    • Keen JC, Yan L, Mack KM, Pettit C, Smith D, Sharma D, Davidson NE. A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine. Breast Cancer Res Treat 2003, 81:177-186. 10.1023/A:1026146524737, 14620913.
    • (2003) Breast Cancer Res Treat , vol.81 , pp. 177-186
    • Keen, J.C.1    Yan, L.2    Mack, K.M.3    Pettit, C.4    Smith, D.5    Sharma, D.6    Davidson, N.E.7
  • 11
    • 33847111684 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation
    • 10.4161/cbt.6.1.3549, 17172825
    • Zhou Q, Atadja P, Davidson NE. Histone deacetylase inhibitor LBH589 reactivates silenced estrogen receptor alpha (ER) gene expression without loss of DNA hypermethylation. Cancer Biol Ther 2007, 6:64-69. 10.4161/cbt.6.1.3549, 17172825.
    • (2007) Cancer Biol Ther , vol.6 , pp. 64-69
    • Zhou, Q.1    Atadja, P.2    Davidson, N.E.3
  • 13
    • 33745685866 scopus 로고    scopus 로고
    • Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifenbound reactivated ER recruits distinctive corepressor complexes
    • 10.1158/0008-5472.CAN-06-0402, 2925469, 16778215
    • Sharma D, Saxena NK, Davidson NE, Vertino PM. Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifenbound reactivated ER recruits distinctive corepressor complexes. Cancer Res 2006, 66:6370-6378. 10.1158/0008-5472.CAN-06-0402, 2925469, 16778215.
    • (2006) Cancer Res , vol.66 , pp. 6370-6378
    • Sharma, D.1    Saxena, N.K.2    Davidson, N.E.3    Vertino, P.M.4
  • 14
    • 79959190386 scopus 로고    scopus 로고
    • Progesterone receptor isoform-specific promoter methylation - Association of PRA methylation with worse outcome in breast cancer patients
    • 10.1158/1078-0432.CCR-10-2950, 21459801
    • Pathiraja TN, Shetty TB, Jelinek J, He R, Hartmaier R, Margossian AL, Hilsenbeck SG, Issa JP, Oesterreich S. Progesterone receptor isoform-specific promoter methylation - Association of PRA methylation with worse outcome in breast cancer patients. Clin Cancer Res 2011, 17:4177-4186. 10.1158/1078-0432.CCR-10-2950, 21459801.
    • (2011) Clin Cancer Res , vol.17 , pp. 4177-4186
    • Pathiraja, T.N.1    Shetty, T.B.2    Jelinek, J.3    He, R.4    Hartmaier, R.5    Margossian, A.L.6    Hilsenbeck, S.G.7    Issa, J.P.8    Oesterreich, S.9
  • 15
    • 33645768490 scopus 로고    scopus 로고
    • Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
    • 10.1371/journal.pgen.0020040, 1420676, 16596166
    • Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet 2006, 2:e40. 10.1371/journal.pgen.0020040, 1420676, 16596166.
    • (2006) PLoS Genet , vol.2
    • Pruitt, K.1    Zinn, R.L.2    Ohm, J.E.3    McGarvey, K.M.4    Kang, S.H.5    Watkins, D.N.6    Herman, J.G.7    Baylin, S.B.8
  • 16
    • 37249013214 scopus 로고    scopus 로고
    • ClinicalTrials.gov
    • ClinicalTrials.gov. , http://clinicaltrials.gov
  • 17
    • 77149122714 scopus 로고    scopus 로고
    • Epigenetic regulation in estrogen receptor positive breast cancer - role in treatment response
    • 10.1007/s10911-010-9166-0, 2874203, 20101445
    • Pathiraja TN, Stearns V, Oesterreich S. Epigenetic regulation in estrogen receptor positive breast cancer - role in treatment response. J Mammary Gland Biol Neoplasia 2010, 15:35-47. 10.1007/s10911-010-9166-0, 2874203, 20101445.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 35-47
    • Pathiraja, T.N.1    Stearns, V.2    Oesterreich, S.3
  • 18
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
    • 10.1038/5047, 9916800
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 1999, 21:103-107. 10.1038/5047, 9916800.
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 21
    • 44749085668 scopus 로고    scopus 로고
    • ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor
    • 10.1007/s00432-008-0354-x, 18264725
    • Fan J, Yin WJ, Lu JS, Wang L, Wu J, Wu FY, Di GH, Shen ZZ, Shao ZM. ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor. J Cancer Res Clin Oncol 2008, 134:883-890. 10.1007/s00432-008-0354-x, 18264725.
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 883-890
    • Fan, J.1    Yin, W.J.2    Lu, J.S.3    Wang, L.4    Wu, J.5    Wu, F.Y.6    Di, G.H.7    Shen, Z.Z.8    Shao, Z.M.9
  • 22
    • 33645083241 scopus 로고    scopus 로고
    • Six (or more) drugs in search of a mechanism: DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes
    • Gore SD. Six (or more) drugs in search of a mechanism: DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes. J Natl Compr Canc Netw 2006, 4:83-90.
    • (2006) J Natl Compr Canc Netw , vol.4 , pp. 83-90
    • Gore, S.D.1
  • 24
    • 27644589675 scopus 로고    scopus 로고
    • The diverse functions of histone lysine methylation
    • 10.1038/nrm1761, 16261189
    • Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 2005, 6:838-849. 10.1038/nrm1761, 16261189.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 838-849
    • Martin, C.1    Zhang, Y.2
  • 25
    • 33847084602 scopus 로고    scopus 로고
    • Genome regulation by polycomb and trithorax proteins
    • 10.1016/j.cell.2007.02.009, 17320510
    • Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007, 128:735-745. 10.1016/j.cell.2007.02.009, 17320510.
    • (2007) Cell , vol.128 , pp. 735-745
    • Schuettengruber, B.1    Chourrout, D.2    Vervoort, M.3    Leblanc, B.4    Cavalli, G.5
  • 26
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • 10.1038/nrc1799, 16491070
    • Baylin S, Ohm J. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?. Nat Rev Cancer 2006, 6:107-116. 10.1038/nrc1799, 16491070.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.1    Ohm, J.2
  • 28
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • 10.1038/70602, 10581039
    • van der Vlag J, Otte AP. Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat Genet 1999, 23:474-478. 10.1038/70602, 10581039.
    • (1999) Nat Genet , vol.23 , pp. 474-478
    • van der Vlag, J.1    Otte, A.P.2
  • 30
    • 33644765912 scopus 로고    scopus 로고
    • Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer
    • 10.1158/1078-0432.CCR-05-1533, 16489070
    • Collett K, Eide GE, Arnes J, Stefansson IM, Eide J, Braaten A, Aas T, Otte AP, Akslen LA. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clin Cancer Res 2006, 12:1168-1174. 10.1158/1078-0432.CCR-05-1533, 16489070.
    • (2006) Clin Cancer Res , vol.12 , pp. 1168-1174
    • Collett, K.1    Eide, G.E.2    Arnes, J.3    Stefansson, I.M.4    Eide, J.5    Braaten, A.6    Aas, T.7    Otte, A.P.8    Akslen, L.A.9
  • 31
    • 33644822360 scopus 로고    scopus 로고
    • EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
    • Bachmann IM, Halvorsen OJ, Collett K, Stefansson IM, Straume O, Haukaas SA, Salvesen HB, Otte AP, Akslen LA. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. J Clin Oncol 2006, 24:268-273.
    • (2006) J Clin Oncol , vol.24 , pp. 268-273
    • Bachmann, I.M.1    Halvorsen, O.J.2    Collett, K.3    Stefansson, I.M.4    Straume, O.5    Haukaas, S.A.6    Salvesen, H.B.7    Otte, A.P.8    Akslen, L.A.9
  • 32
    • 78651454089 scopus 로고    scopus 로고
    • EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling
    • 10.1016/j.ccr.2010.10.035, 21215703
    • Chang CJ, Yang JY, Xia W, Chen CT, Xie X, Chao CH, Woodward WA, Hsu JM, Hortobagyi GN, Hung MC. EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-beta-catenin signaling. Cancer Cell 2011, 19:86-100. 10.1016/j.ccr.2010.10.035, 21215703.
    • (2011) Cancer Cell , vol.19 , pp. 86-100
    • Chang, C.J.1    Yang, J.Y.2    Xia, W.3    Chen, C.T.4    Xie, X.5    Chao, C.H.6    Woodward, W.A.7    Hsu, J.M.8    Hortobagyi, G.N.9    Hung, M.C.10
  • 33
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • 10.1016/j.cell.2004.12.012, 15620353
    • Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004, 119:941-953. 10.1016/j.cell.2004.12.012, 15620353.
    • (2004) Cell , vol.119 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5    Cole, P.A.6    Casero, R.A.7
  • 34
    • 25144519737 scopus 로고    scopus 로고
    • An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
    • Lee MG, Wynder C, Cooch N, Shiekhattar R. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature 2005, 437:432-435.
    • (2005) Nature , vol.437 , pp. 432-435
    • Lee, M.G.1    Wynder, C.2    Cooch, N.3    Shiekhattar, R.4
  • 35
    • 77950868547 scopus 로고    scopus 로고
    • Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology
    • 10.1093/carcin/bgp324, 20042638
    • Lim S, Janzer A, Becker A, Zimmer A, Schule R, Buettner R, Kirfel J. Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology. Carcinogenesis 2010, 31:512-520. 10.1093/carcin/bgp324, 20042638.
    • (2010) Carcinogenesis , vol.31 , pp. 512-520
    • Lim, S.1    Janzer, A.2    Becker, A.3    Zimmer, A.4    Schule, R.5    Buettner, R.6    Kirfel, J.7
  • 38
    • 84856221673 scopus 로고    scopus 로고
    • Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells
    • [Epub ahead of print]
    • Huang Y, Vasilatos SN, Boric L, Shaw PG, Davidson NE. Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells. Breast Cancer Res Treat 2011, [Epub ahead of print].
    • (2011) Breast Cancer Res Treat
    • Huang, Y.1    Vasilatos, S.N.2    Boric, L.3    Shaw, P.G.4    Davidson, N.E.5
  • 42
    • 33745847680 scopus 로고    scopus 로고
    • The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    • 10.1038/nature04853, 16732292
    • Klose RJ, Yamane K, Bae Y, Zhang D, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature 2006, 442:312-316. 10.1038/nature04853, 16732292.
    • (2006) Nature , vol.442 , pp. 312-316
    • Klose, R.J.1    Yamane, K.2    Bae, Y.3    Zhang, D.4    Erdjument-Bromage, H.5    Tempst, P.6    Wong, J.7    Zhang, Y.8
  • 43
    • 33646138230 scopus 로고    scopus 로고
    • JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor
    • 10.1016/j.cell.2006.03.027, 16603237
    • Yamane K, Toumazou C, Tsukada Y, Erdjument-Bromage H, Tempst P, Wong J, Zhang Y. JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 2006, 125:483-495. 10.1016/j.cell.2006.03.027, 16603237.
    • (2006) Cell , vol.125 , pp. 483-495
    • Yamane, K.1    Toumazou, C.2    Tsukada, Y.3    Erdjument-Bromage, H.4    Tempst, P.5    Wong, J.6    Zhang, Y.7
  • 48
    • 30644474460 scopus 로고    scopus 로고
    • Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9
    • Greiner D, Bonaldi T, Eskeland R, Roemer E, Imhof A. Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. Nat Chem Biol 2005, 1:143-145.
    • (2005) Nat Chem Biol , vol.1 , pp. 143-145
    • Greiner, D.1    Bonaldi, T.2    Eskeland, R.3    Roemer, E.4    Imhof, A.5
  • 49
    • 34247625135 scopus 로고    scopus 로고
    • Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
    • 10.1101/gad.1524107, 1855231, 17437993
    • Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. Genes Dev 2007, 21:1050-1063. 10.1101/gad.1524107, 1855231, 17437993.
    • (2007) Genes Dev , vol.21 , pp. 1050-1063
    • Tan, J.1    Yang, X.2    Zhuang, L.3    Jiang, X.4    Chen, W.5    Lee, P.L.6    Karuturi, R.K.7    Tan, P.B.8    Liu, E.T.9    Yu, Q.10
  • 50
    • 33644929027 scopus 로고    scopus 로고
    • Enhanced SMYD3 expression is essential for the growth of breast cancer cells
    • 10.1111/j.1349-7006.2006.00146.x, 16441421
    • Hamamoto R, Silva FP, Tsuge M, Nishidate T, Katagiri T, Nakamura Y, Furukawa Y. Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Sci 2006, 97:113-118. 10.1111/j.1349-7006.2006.00146.x, 16441421.
    • (2006) Cancer Sci , vol.97 , pp. 113-118
    • Hamamoto, R.1    Silva, F.P.2    Tsuge, M.3    Nishidate, T.4    Katagiri, T.5    Nakamura, Y.6    Furukawa, Y.7
  • 51
    • 77951122152 scopus 로고    scopus 로고
    • Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells
    • Luo XG, Zou JN, Wang SZ, Zhang TC, Xi T. Novobiocin decreases SMYD3 expression and inhibits the migration of MDA-MB-231 human breast cancer cells. IUBMB Life 2010, 62:194-199.
    • (2010) IUBMB Life , vol.62 , pp. 194-199
    • Luo, X.G.1    Zou, J.N.2    Wang, S.Z.3    Zhang, T.C.4    Xi, T.5
  • 52
    • 33745187327 scopus 로고    scopus 로고
    • Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications
    • 10.1016/j.chembiol.2006.05.004, 16793513
    • Lee M, Wynder C, Schmidt D, McCafferty D, Shiekhattar R. Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol 2006, 13:563-567. 10.1016/j.chembiol.2006.05.004, 16793513.
    • (2006) Chem Biol , vol.13 , pp. 563-567
    • Lee, M.1    Wynder, C.2    Schmidt, D.3    McCafferty, D.4    Shiekhattar, R.5
  • 54
    • 34249934238 scopus 로고    scopus 로고
    • Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
    • 10.1073/pnas.0700720104, 1857229, 17463086
    • Huang Y, Greene E, Stewart TM, Goodwin AC, Baylin SB, Woster PM, Casero RA. Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. Proc Natl Acad Sci USA 2007, 104:8023-8028. 10.1073/pnas.0700720104, 1857229, 17463086.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8023-8028
    • Huang, Y.1    Greene, E.2    Stewart, T.M.3    Goodwin, A.C.4    Baylin, S.B.5    Woster, P.M.6    Casero, R.A.7
  • 55
    • 73149118652 scopus 로고    scopus 로고
    • Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
    • 10.1158/1078-0432.CCR-09-1293, 2927136, 19934284
    • Huang Y, Stewart TM, Wu Y, Baylin SB, Marton LJ, Perkins B, ones RJ, Woster PM Casero JRA. Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. Clin Cancer Res 2009, 15:7217-7228. 10.1158/1078-0432.CCR-09-1293, 2927136, 19934284.
    • (2009) Clin Cancer Res , vol.15 , pp. 7217-7228
    • Huang, Y.1    Stewart, T.M.2    Wu, Y.3    Baylin, S.B.4    Marton, L.J.5    Perkins, B.6    ones, R.J.7    Woster PM Casero, J.R.A.8
  • 56
    • 84862673738 scopus 로고    scopus 로고
    • Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells
    • [Epub ahead of print]
    • Zhu Q, Huang Y, Marton LJ, Woster PM, Davidson NE, Casero RA. Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells. Amino Acids 2011, [Epub ahead of print].
    • (2011) Amino Acids
    • Zhu, Q.1    Huang, Y.2    Marton, L.J.3    Woster, P.M.4    Davidson, N.E.5    Casero, R.A.6
  • 59
    • 77149122714 scopus 로고    scopus 로고
    • Epigenetic regulation in estrogen receptor positive breast cancer - role in treatment response
    • 10.1007/s10911-010-9166-0, 2874203, 20101445
    • Pathiraja TN, Stearns V, Oesterreich S. Epigenetic regulation in estrogen receptor positive breast cancer - role in treatment response. J Mammary Gland Biol Neoplasia 2010, 15:35-47. 10.1007/s10911-010-9166-0, 2874203, 20101445.
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 35-47
    • Pathiraja, T.N.1    Stearns, V.2    Oesterreich, S.3
  • 60
    • 0036389638 scopus 로고    scopus 로고
    • BRCA1 methylation: a significant role in tumour development?
    • 10.1016/S1044-579X(02)00056-1, 12191635
    • Catteau A, Morris JR. BRCA1 methylation: a significant role in tumour development?. Semin Cancer Biol 2002, 12:359-371. 10.1016/S1044-579X(02)00056-1, 12191635.
    • (2002) Semin Cancer Biol , vol.12 , pp. 359-371
    • Catteau, A.1    Morris, J.R.2
  • 63
    • 38049073696 scopus 로고    scopus 로고
    • Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA
    • 2134785, 18032725
    • Korshunova Y, Maloney RK, Lakey N, Citek RW, Bacher B, Budiman A, Ordway JM, McCombie WR, Leon J, Jeddeloh JA, McPherson JD. Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA. Genome Res 2008, 18:19-29. 2134785, 18032725.
    • (2008) Genome Res , vol.18 , pp. 19-29
    • Korshunova, Y.1    Maloney, R.K.2    Lakey, N.3    Citek, R.W.4    Bacher, B.5    Budiman, A.6    Ordway, J.M.7    McCombie, W.R.8    Leon, J.9    Jeddeloh, J.A.10    McPherson, J.D.11
  • 64
    • 77950409567 scopus 로고    scopus 로고
    • Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing
    • 10.1186/1471-2164-11-137, 2838848, 20181289
    • Ruike Y, Imanaka Y, Sato F, Shimizu K, Tsujimoto G. Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing. BMC Genomics 2010, 11:137. 10.1186/1471-2164-11-137, 2838848, 20181289.
    • (2010) BMC Genomics , vol.11 , pp. 137
    • Ruike, Y.1    Imanaka, Y.2    Sato, F.3    Shimizu, K.4    Tsujimoto, G.5
  • 66
    • 79952716583 scopus 로고    scopus 로고
    • Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer
    • 10.1073/pnas.1013224108, 3060255, 21368160
    • Sproul D, Nestor C, Culley J, Dickson JH, Dixon JM, Harrison DJ, Meehan RR, Sims AH, Ramsahoye BH. Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proc Natl Acad Sci USA 2011, 108:4364-4369. 10.1073/pnas.1013224108, 3060255, 21368160.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4364-4369
    • Sproul, D.1    Nestor, C.2    Culley, J.3    Dickson, J.H.4    Dixon, J.M.5    Harrison, D.J.6    Meehan, R.R.7    Sims, A.H.8    Ramsahoye, B.H.9
  • 67
    • 84944035947 scopus 로고    scopus 로고
    • International Human Epigenome Consortium
    • International Human Epigenome Consortium. , http://www.ihec-epigenomes.org
  • 70
    • 78650747491 scopus 로고    scopus 로고
    • Discovery and characterization of chromatin states for systematic annotation of the human genome
    • 10.1038/nbt.1662, 2919626, 20657582
    • Ernst J, Kellis M. Discovery and characterization of chromatin states for systematic annotation of the human genome. Nat Biotechnol 2010, 28:817-825. 10.1038/nbt.1662, 2919626, 20657582.
    • (2010) Nat Biotechnol , vol.28 , pp. 817-825
    • Ernst, J.1    Kellis, M.2
  • 73
    • 0030977226 scopus 로고    scopus 로고
    • An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region
    • 10.1074/jbc.272.17.11463, 9111059
    • Dickinson LA, Dickinson CD, Kohwi-Shigematsu T. An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region. J Biol Chem 1997, 272:11463-11470. 10.1074/jbc.272.17.11463, 9111059.
    • (1997) J Biol Chem , vol.272 , pp. 11463-11470
    • Dickinson, L.A.1    Dickinson, C.D.2    Kohwi-Shigematsu, T.3
  • 74
    • 0032550174 scopus 로고    scopus 로고
    • The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops
    • 10.1083/jcb.141.2.335, 2148460, 9548713
    • de Belle I, Cai S, Kohwi-Shigematsu T. The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. J Cell Biol 1998, 141:335-348. 10.1083/jcb.141.2.335, 2148460, 9548713.
    • (1998) J Cell Biol , vol.141 , pp. 335-348
    • de Belle, I.1    Cai, S.2    Kohwi-Shigematsu, T.3
  • 75
    • 0034161939 scopus 로고    scopus 로고
    • The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development
    • 316425, 10716941
    • Alvarez JD, Yasui DH, Niida H, Joh T, Loh DY, ohwi-Shigematsu T. The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Genes Dev 2000, 14:521-535. 316425, 10716941.
    • (2000) Genes Dev , vol.14 , pp. 521-535
    • Alvarez, J.D.1    Yasui, D.H.2    Niida, H.3    Joh, T.4    Loh, D.Y.5    ohwi-Shigematsu, T.6
  • 76
    • 40749094918 scopus 로고    scopus 로고
    • SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
    • 10.1038/nature06781, 18337816
    • Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008, 452:187-193. 10.1038/nature06781, 18337816.
    • (2008) Nature , vol.452 , pp. 187-193
    • Han, H.J.1    Russo, J.2    Kohwi, Y.3    Kohwi-Shigematsu, T.4
  • 78
    • 33750465872 scopus 로고    scopus 로고
    • SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes
    • 10.1038/ng1913, 17057718
    • Cai S, Lee CC, Kohwi-Shigematsu T. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes. Nat Genet 2006, 38:1278-1288. 10.1038/ng1913, 17057718.
    • (2006) Nat Genet , vol.38 , pp. 1278-1288
    • Cai, S.1    Lee, C.C.2    Kohwi-Shigematsu, T.3
  • 79
    • 79952254109 scopus 로고    scopus 로고
    • Cancer. New epigenetic drivers of cancers
    • 10.1126/science.1203280, 21385704
    • Elsasser SJ, Allis CD, Lewis PW. Cancer. New epigenetic drivers of cancers. Science 2011, 331:1145-1146. 10.1126/science.1203280, 21385704.
    • (2011) Science , vol.331 , pp. 1145-1146
    • Elsasser, S.J.1    Allis, C.D.2    Lewis, P.W.3
  • 80
    • 84907680521 scopus 로고    scopus 로고
    • Roadmap Epigenomics Project
    • Roadmap Epigenomics Project. , http://www.roadmapepigenomics.org/data
  • 81
    • 77957969687 scopus 로고    scopus 로고
    • Putting epigenome comparison into practice
    • 10.1038/nbt1010-1053, 20944597
    • Milosavljevic A. Putting epigenome comparison into practice. Nat Biotechnol 2010, 28:1053-1056. 10.1038/nbt1010-1053, 20944597.
    • (2010) Nat Biotechnol , vol.28 , pp. 1053-1056
    • Milosavljevic, A.1
  • 82
    • 84864819611 scopus 로고    scopus 로고
    • The Cancer Genome Atlas Data Portal
    • The Cancer Genome Atlas Data Portal. , http://tcga-data.nci.nih.gov/tcga/


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.