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Mavridou E, Bruggemann RJ, Melchers WJ, et al. Efficacy of posaconazole against three clinical Aspergillus fumigatus isolates with mutations in the cyp51A gene. Antimicrob Agents Chemother. 2010;54:860-5.
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Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: Clinical implications for antifungal therapy
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Howard SJ, Lestner JM, Sharp A, et al. Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapy. J Infect Dis. 2011;203:1324-32.
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Data mining validation of fluconazole breakpoints established by the European Committee on Antimicrobial Susceptibility Testing
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This article shows that the validation of clinical breakpoints can be done by means of data mining. With this approach, the sensitivity, specificity, false-positive rate, and area under the ROC curve are obtained
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Cuesta I, Bielza C, Larranaga P, et al. Data mining validation of fluconazole breakpoints established by the European Committee on Antimicrobial Susceptibility Testing. Antimicrob Agents Chemother 2009;53:2949-54. This article shows that the validation of clinical breakpoints can be done by means of data mining. With this approach, the sensitivity, specificity, false-positive rate, and area under the ROC curve are obtained.
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Cuesta, I.1
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Correlation of the MIC and dose/MIC ratio of fluconazole to the therapeutic response of patients with mucosal candidiasis and candidemia
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Rodriguez-Tudela JL, Almirante B, Rodriguez-Pardo D, et al. Correlation of the MIC and dose/MIC ratio of fluconazole to the therapeutic response of patients with mucosal candidiasis and candidemia. Antimicrob Agents Chemother. 2007;51:3599-604. (Pubitemid 47519349)
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Multiple-azoleresistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery
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Hodiamont CJ, Dolman KM, Ten berge IJM, et al. Multiple-azoleresistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery. Med Mycol. 2009;47:217-20.
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Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis
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This article shows the outcome of several patients with azole-resistant strains of A. fumigatus
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Howard SJ, Pasqualotto AC, Denning DW. Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis. Clin Microbiol Infect 2010;16:683-8. This article shows the outcome of several patients with azole-resistant strains of A. fumigatus.
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Howard, S.J.1
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