KRN/I-Ag7 mouse arthritis is independent of complement C3

Journal of Clinical Immunology

Volumn 31, Issue 5, 2011, Pages 857-863

  Tsao, Patricia Y ^a   Arora, Vaishali ^a   Ji, Mei Qing ^a   Wright, Alexander C ^a   Eisenberg, Robert A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Arthritis; autoantibody; complement C3; GPI; KRN

Indexed keywords

AUTOANTIBODY; COMPLEMENT COMPONENT C3; GLUCOSE 6 PHOSPHATE ISOMERASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; AUTOANTIGEN; HLA ANTIGEN CLASS 2; I A G7 ANTIGEN; I-A G7 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY DETECTION; ARTICLE; BLOOD TRANSFUSION; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; IMMUNOPATHOLOGY; MALE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; ANIMAL; BLOOD; C57BL MOUSE; COMPLEMENT ACTIVATION; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; PASSIVE IMMUNIZATION; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; COMPLEMENT ACTIVATION; COMPLEMENT C3; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE-6-PHOSPHATE ISOMERASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNIZATION, PASSIVE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC;

EID: 80755153225     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-011-9562-2     Document Type: Article

References (33)

1. DM Lee ME Weinblatt 2001 Rheumatoid arthritis Lancet 358 903 11 11567728 10.1016/S0140-6736(01)06075-5 1:CAS:528:DC%2BD3MXmvVKmtr8%3D (Pubitemid 32900579)
2. M Feldmann FM Brennan RN Maini 1996 Rheumatoid arthritis Cell 85 307 10 8616886 10.1016/S0092-8674(00)81109-5 1:CAS:528:DyaK28XivVyrs7w%3D (Pubitemid 26160702)
3. DA Fox 1997 The role of T cells in the immunopathogenesis of rheumatoid arthritis: new perspectives Arthritis Rheum 40 598 609 9125240 10.1002/art.1780400403 1:STN:280:DyaK2s3ksVaqsA%3D%3D (Pubitemid 27157563)
4. SB Petkova KN Konstantinov TJ Sproule BL Lyons MA Awwami DC Roopenian 2006 Human antibodies induce arthritis in mice deficient in the low-affinity inhibitory IgG receptor Fc gamma RIIB J Exp Med 203 275 80 16476768 10.1084/jem.20051951 (Pubitemid 43290836)
5. P Youinou C Jamin A Saraux 2007 B-cell: a logical target for treatment of rheumatoid arthritis Clin Exp Rheumatol 25 318 28 17543163 1:STN:280: DC%2BD2szjtF2mug%3D%3D (Pubitemid 46851441)
6. JS Smolen EC Keystone P Emery FC Breedveld N Betteridge GR Burmester M Dougados G Ferraccioli U Jaeger L Klareskog TK Kvien E Martin-Mola K Pavelka 2007 Consensus statement on the use of rituximab in patients with rheumatoid arthritis Ann Rheum Dis 66 143 50 17068064 10.1136/ard.2006.061002 1:CAS:528:DC%2BD2sXislChs74%3D (Pubitemid 46226045)
7. PA Monach C Benoist D Mathis 2004 The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease Adv Immunol 82 217 48 14975258 10.1016/S0065-2776(04)82005-4 1:CAS:528:DC%2BD2cXivFCjurc%3D (Pubitemid 38209512)
8. V Kouskoff AS Korganow V Duchatelle C Degott C Benoist D Mathis 1996 Organ-specific disease provoked by systemic autoimmunity Cell 87 811 22 8945509 10.1016/S0092-8674(00)81989-3 1:CAS:528:DyaK28Xntlymsbs%3D (Pubitemid 26404281)
9. E Carrasco-Marin J Shimizu O Kanagawa ER Unanue 1996 The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders J Immunol 156 450 8 8543793 1:CAS:528:DyaK28XksV2lsQ%3D%3D
10. I Matsumoto A Staub C Benoist D Mathis 1999 Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme Science (New York, N.Y) 286 1732 5 10.1126/science.286.5445.1732 1:CAS:528:DyaK1MXnsl2gurg%3D (Pubitemid 129515879)
11. D Basu S Horvath I Matsumoto DH Fremont PM Allen 2000 Molecular basis for recognition of an arthritic peptide and a foreign epitope on distinct MHC molecules by a single TCR J Immunol 164 5788 96 10820257 1:CAS:528: DC%2BD3cXjslemt7w%3D (Pubitemid 30389822)
12. AS Korganow H Ji S Mangialaio V Duchatelle R Pelanda T Martin C Degott H Kikutani K Rajewsky JL Pasquali C Benoist D Mathis 1999 From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins Immunity 10 451 61 10229188 10.1016/S1074-7613(00)80045-X 1:CAS:528: DyaK1MXjtVart7g%3D (Pubitemid 29205481)
13. H Ji D Gauguier K Ohmura A Gonzalez V Duchatelle P Danoy HJ Garchon C Degott M Lathrop C Benoist D Mathis 2001 Genetic influences on the end-stage effector phase of arthritis J Exp Med 194 321 30 11489951 10.1084/jem.194.3.321 1:CAS:528:DC%2BD3MXlvFShu7k%3D (Pubitemid 32730806)
14. S Solomon N Rajasekaran E Jeisy-Walder SB Snapper H Illges 2005 A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis Eur J Immunol 35 3064 73 16180250 10.1002/eji.200526167 1:CAS:528:DC%2BD2MXhtFKjt7nN (Pubitemid 41555102)
15. A Circolo G Garnier W Fukuda X Wang T Hidvegi AJ Szalai DE Briles JE Volanakis RA Wetsel HR Colten 1999 Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA Immunopharmacology 42 135 49 10408374 10.1016/S0162-3109(99)00021-1 1:CAS:528:DyaK1MXjs1Siu74%3D (Pubitemid 29322296)
16. PA Monach A Verschoor JP Jacobs MC Carroll AJ Wagers C Benoist D Mathis 2007 Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model Arthritis Rheum 56 2968 74 17763447 10.1002/art.22859 (Pubitemid 47502743)
17. S Solomon C Kolb S Mohanty E Jeisy-Walder R Preyer V Schollhorn H Illges 2002 Transmission of antibody-induced arthritis is independent of complement component 4 (C4) and the complement receptors 1 and 2 (CD21/35) Eur J Immunol 32 644 51 11857338 10.1002/1521-4141(200203)32:3<644::AID-IMMU644>3.0.CO;2-5 1:CAS:528:DC%2BD38Xitl2nsrw%3D (Pubitemid 34257541)
18. H Ji AS Korganow S Mangialaio P Hoglund I Andre F Luhder A Gonzalez L Poirot C Benoist D Mathis 1999 Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems Immunol Rev 169 139 46 10450514 10.1111/j.1600-065X.1999.tb01312.x 1:STN:280: DyaK1MznvFSjug%3D%3D (Pubitemid 29338729)
19. DM Lee DS Friend MF Gurish C Benoist D Mathis MB Brenner 2002 Mast cells: a cellular link between autoantibodies and inflammatory arthritis Science (New York, N.Y) 297 1689 92 10.1126/science.1073176 1:CAS:528:DC%2BD38XmvFymtL0%3D (Pubitemid 35000781)
20. BT Wipke PM Allen 2001 Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis J Immunol 167 1601 8 11466382 1:CAS:528:DC%2BD3MXls1WrsL4%3D (Pubitemid 32703161)
21. Monach PA, Mathis D, Benoist C. The K/BxN arthritis model. In: Coligan JE et al., editors. Current protocols in immunology, Chapter 15: Unit 15 22. New York: Wiley; 2008.
22. PY Tsao J Jiao MQ Ji PL Cohen RA Eisenberg 2008 T cell-independent spontaneous loss of tolerance by anti-double-stranded DNA B cells in C57BL/6 mice J Immunol 181 7770 7 19017966 1:CAS:528:DC%2BD1cXhtl2gsL7P
23. H Ji K Ohmura U Mahmood DM Lee FM Hofhuis SA Boackle K Takahashi VM Holers M Walport C Gerard A Ezekowitz MC Carroll M Brenner R Weissleder JS Verbeek V Duchatelle C Degott C Benoist D Mathis 2002 Arthritis critically dependent on innate immune system players Immunity 16 157 68 11869678 10.1016/S1074-7613(02)00275-3 1:CAS:528:DC%2BD38XitVCju7k%3D (Pubitemid 34211957)
24. M Maccioni G Zeder-Lutz H Huang C Ebel P Gerber J Hergueux P Marchal V Duchatelle C Degott M van Regenmortel C Benoist D Mathis 2002 Arthritogenic monoclonal antibodies from K/BxN mice J Exp Med 195 1071 7 11956298 10.1084/jem.20011941 1:CAS:528:DC%2BD38XivFyksbo%3D (Pubitemid 34412009)
25. M Kneilling L Hultner BJ Pichler R Mailhammer L Morawietz S Solomon M Eichner J Sabatino T Biedermann V Krenn WA Weber H Illges R Haubner M Rocken 2007 Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice Arthritis Rheum 56 1806 16 17530709 10.1002/art.22602 1:CAS:528:DC%2BD2sXnsVOhtL0%3D (Pubitemid 47110380)
26. PA Monach PA Nigrovic M Chen H Hock DM Lee C Benoist D Mathis 2010 Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1 Arthritis Rheum 62 753 64 20191628 10.1002/art.27238 1:CAS:528:DC%2BC3cXhtFaltLrL
27. P Victoratos G Kollias 2009 Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells Immunity 30 130 42 19119026 10.1016/j.immuni.2008.10.019 1:CAS:528:DC%2BD1MXhtlCnsbs%3D
28. BR Raposo P Rodrigues-Santos H Carvalheiro AM Agua-Doce L Carvalho JA Pereira da Silva L Graca MM Souto-Carneiro 2010 Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse model of spontaneous chronic polyarthritis Arthritis Rheum 62 2953 62 20931654 10.1002/art.27729 1:CAS:528:DC%2BC3cXhsVSqtrvO
29. S Einav OO Pozdnyakova M Ma MC Carroll 2002 Complement C4 is protective for lupus disease independent of C3 J Immunol 168 1036 41 11801636 1:CAS:528:DC%2BD38XpsFegtw%3D%3D (Pubitemid 34094466)
30. H Sekine CM Reilly ID Molano G Garnier A Circolo P Ruiz VM Holers SA Boackle GS Gilkeson 2001 Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice J Immunol 166 6444 51 11342671 1:CAS:528:DC%2BD3MXjsFCqtbo%3D (Pubitemid 32440780)
31. MK Elliott T Jarmi P Ruiz Y Xu VM Holers GS Gilkeson 2004 Effects of complement factor D deficiency on the renal disease of MRL/lpr mice Kidney Int 65 129 38 14675043 10.1111/j.1523-1755.2004.00371.x 1:CAS:528: DC%2BD2cXmt1Wjtw%3D%3D (Pubitemid 38037497)
32. H Watanabe G Garnier A Circolo RA Wetsel P Ruiz VM Holers SA Boackle HR Colten GS Gilkeson 2000 Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B J Immunol 164 786 94 10623824 1:CAS:528:DC%2BD3cXlt1CmtA%3D%3D (Pubitemid 30043702)
33. AJ Swaak A Van Rooyen O Planten H Han O Hattink E Hack 1987 An analysis of the levels of complement components in the synovial fluid in rheumatic diseases Clin Rheumatol 6 350 7 3442962 10.1007/BF02206833 1:STN:280: DyaL1c7msFyitQ%3D%3D