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Volumn 1811, Issue 12, 2011, Pages 1136-1145

Synthetic LXR agonist inhibits the development of atherosclerosis in New Zealand White rabbits

Author keywords

Atherosclerosis; CETP; Cloning; HDL; LXR; Rabbit

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; LIPID; LIVER X RECEPTOR AGONIST; LIVER X RECEPTOR ALPHA; LIVER X RECEPTOR BETA; LOW DENSITY LIPOPROTEIN; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; TRIACYLGLYCEROL;

EID: 80755143100     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2011.08.009     Document Type: Article
Times cited : (20)

References (40)
  • 1
    • 0035851188 scopus 로고    scopus 로고
    • Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism
    • T.T. Lu, J.J. Repa, and D.J. Mangelsdorf Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism J. Biol. Chem. 276 2001 37735 37738
    • (2001) J. Biol. Chem. , vol.276 , pp. 37735-37738
    • Lu, T.T.1    Repa, J.J.2    Mangelsdorf, D.J.3
  • 3
    • 0028836714 scopus 로고
    • Isolation of proteins that interact specifically with the retinoid X receptor: Two novel orphan receptors
    • W. Seol, H.S. Choi, and D.D. Moore Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors Mol. Endocrinol. 9 1995 72 85
    • (1995) Mol. Endocrinol. , vol.9 , pp. 72-85
    • Seol, W.1    Choi, H.S.2    Moore, D.D.3
  • 5
    • 0028918963 scopus 로고
    • OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor
    • M. Teboul, E. Enmark, and Q. Li OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor Proc. Natl. Acad. Sci. U.S.A. 92 1995 2096 2100
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 2096-2100
    • Teboul, M.1    Enmark, E.2    Li, Q.3
  • 6
    • 0028025654 scopus 로고
    • A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily
    • R. Apfel, D. Benbrook, and E. Lernhardt A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily Mol. Cell. Biol. 14 1994 7025 7035
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7025-7035
    • Apfel, R.1    Benbrook, D.2    Lernhardt, E.3
  • 7
    • 0028059845 scopus 로고
    • NER, a new member of the gene family encoding the human steroid hormone nuclear receptor
    • DOI 10.1016/0378-1119(94)90080-9
    • D.M. Shinar, N. Endo, and S.J. Rutledge NER, a new member of the gene family encoding the human steroid hormone nuclear receptor Gene 147 1994 273 276 (Pubitemid 24306344)
    • (1994) Gene , vol.147 , Issue.2 , pp. 273-276
    • Shinar, D.M.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Rodan, G.A.5    Schmidt, A.6
  • 8
    • 0031042762 scopus 로고    scopus 로고
    • Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
    • P.J. Willy, and D.J. Mangelsdorf Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR Genes Dev. 11 1997 289 298 (Pubitemid 27079907)
    • (1997) Genes and Development , vol.11 , Issue.3 , pp. 289-298
    • Willy, P.J.1    Mangelsdorf, D.J.2
  • 9
    • 0029805887 scopus 로고    scopus 로고
    • An oxysterol signalling pathway mediated by the nuclear receptor LXRα
    • DOI 10.1038/383728a0
    • B.A. Janowski, P.J. Willy, and T.R. Devi An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha Nature 383 1996 728 731 (Pubitemid 26360651)
    • (1996) Nature , vol.383 , Issue.6602 , pp. 728-731
    • Janowski, B.A.1    Willy, P.J.2    Devi, T.R.3    Falck, J.R.4    Mangelsdorf, D.J.5
  • 12
    • 0034284918 scopus 로고    scopus 로고
    • Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
    • J.J. Repa, S.D. Turley, and J.A. Lobaccaro Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers Science 289 2000 1524 1529
    • (2000) Science , vol.289 , pp. 1524-1529
    • Repa, J.J.1    Turley, S.D.2    Lobaccaro, J.A.3
  • 13
    • 0034623288 scopus 로고    scopus 로고
    • Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
    • P. Costet, Y. Luo, and N. Wang Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor J. Biol. Chem. 275 2000 28240 28245
    • (2000) J. Biol. Chem. , vol.275 , pp. 28240-28245
    • Costet, P.1    Luo, Y.2    Wang, N.3
  • 14
    • 0034640288 scopus 로고    scopus 로고
    • Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages
    • A. Venkateswaran, J.J. Repa, and J.-M. Lobaccaro Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages J. Biol. Chem. 275 2000 14700 14707
    • (2000) J. Biol. Chem. , vol.275 , pp. 14700-14707
    • Venkateswaran, A.1    Repa, J.J.2    Lobaccaro, J.-M.3
  • 17
    • 0037432165 scopus 로고    scopus 로고
    • T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice
    • DOI 10.1016/S0014-5793(02)03578-0, PII S0014579302035780
    • N. Terasaka, A. Hiroshima, and T. Koieyama T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice FEBS Lett. 536 2003 6 11 (Pubitemid 36206397)
    • (2003) FEBS Letters , vol.536 , Issue.1-3 , pp. 6-11
    • Terasaka, N.1    Hiroshima, A.2    Koieyama, T.3    Ubukata, N.4    Morikawa, Y.5    Nakai, D.6    Inaba, T.7
  • 19
    • 77955129487 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways and atherosclerosis
    • A.C. Calkin, and P. Tontonoz Liver X receptor signaling pathways and atherosclerosis Arterioscler. Thromb. Vasc. Biol. 30 2010 1513 1518
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 1513-1518
    • Calkin, A.C.1    Tontonoz, P.2
  • 20
    • 0034669171 scopus 로고    scopus 로고
    • Role of LXRs in control of lipogenesis
    • J.R. Schultz, H. Tu, and A. Luk Role of LXRs in control of lipogenesis Genes Dev. 14 2000 2831 2838
    • (2000) Genes Dev. , vol.14 , pp. 2831-2838
    • Schultz, J.R.1    Tu, H.2    Luk, A.3
  • 23
    • 0033997752 scopus 로고    scopus 로고
    • Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
    • Y. Luo, and A.R. Tall Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element J. Clin. Invest. 106 2000 513 520 (Pubitemid 30127252)
    • (2000) Journal of Clinical Investigation , vol.105 , Issue.4 , pp. 513-520
    • Luo, Y.1    Tall, A.R.2
  • 24
    • 77956230932 scopus 로고    scopus 로고
    • LXRα regulates human CETP expression in vitro and in transgenic mice
    • S. Honzumi, A. Shima, and A. Hiroshima LXRα regulates human CETP expression in vitro and in transgenic mice Atherosclerosis 212 2010 139 145
    • (2010) Atherosclerosis , vol.212 , pp. 139-145
    • Honzumi, S.1    Shima, A.2    Hiroshima, A.3
  • 25
    • 42649134146 scopus 로고    scopus 로고
    • HDL, ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis
    • DOI 10.1016/j.cmet.2008.03.001, PII S1550413108000727
    • A.R. Tall, L. Yvan-Charvet, and N. Terasaka HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis Cell Metab. 7 2008 365 375 (Pubitemid 351598023)
    • (2008) Cell Metabolism , vol.7 , Issue.5 , pp. 365-375
    • Tall, A.R.1    Yvan-Charvet, L.2    Terasaka, N.3    Pagler, T.4    Wang, N.5
  • 28
    • 55349087953 scopus 로고    scopus 로고
    • Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells
    • E.A. DiBlasio-Smith, M. Arai, and E.M. Quinet Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells J. Transl. Med. 6 2008 59
    • (2008) J. Transl. Med. , vol.6 , pp. 59
    • Diblasio-Smith, E.A.1    Arai, M.2    Quinet, E.M.3
  • 32
    • 0037385266 scopus 로고    scopus 로고
    • LXRs: New therapeutic targets in atherosclerosis?
    • DOI 10.1016/S1471-4892(03)00009-2, PII S1471489203000092
    • S.B. Joseph, and P. Tontonoz LXRs: new therapeutic targets in atherosclerosis? Curr. Opin. Pharmacol. 3 2003 192 197 (Pubitemid 36411245)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.2 , pp. 192-197
    • Joseph, S.B.1    Tontonoz, P.2
  • 34
    • 58149386896 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: Insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
    • S.J. Nicholls, E.M. Tuzcu, and D.M. Brennan Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation) Circulation 118 2008 2506 2514
    • (2008) Circulation , vol.118 , pp. 2506-2514
    • Nicholls, S.J.1    Tuzcu, E.M.2    Brennan, D.M.3
  • 40
    • 0036851863 scopus 로고    scopus 로고
    • The liver X receptor gene team: Potential new players in atherosclerosis
    • DOI 10.1038/nm1102-1243
    • J.J. Repa, and D.J. Mangelsdorf The liver X receptor gene team: potential new players in atherosclerosis Nat. Med. 9 2002 1243 1248 (Pubitemid 35373555)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1243-1248
    • Repa, J.J.1    Mangelsdorf, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.