EGFRvIII-mediated radioresistance through a strong cytoprotective response

Oncogene

Volumn 22, Issue 36, 2003, Pages 5545-5553

  Lammering, Guido ^a   Hewit, Theodore H ^b   Valerie, Kristoffer ^b   Contessa, Joseph N ^b   Amorino, George P ^b   Dent, Paul ^b   Schmidt Ullrich, Rupert K ^b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

AKT; EGFR; EGFRvIII; MAP kinase; PI3 kinase; Radiation

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENIC ACTIVITY; CELL PROTECTION; CHO CELL; COLONY FORMING CELL; CONTROLLED STUDY; DOWNSTREAM PROCESSING; GENETIC TRANSFECTION; GLIOBLASTOMA; IONIZING RADIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIATION DOSE; RADIATION EXPOSURE; RADIOSENSITIVITY; TARGET CELL; TUMOR CELL; WILD TYPE; XENOGRAFT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CHO CELLS; CRICETINAE; CYTOPROTECTION; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION TOLERANCE; RECEPTOR, EPIDERMAL GROWTH FACTOR; TYRPHOSTINS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0042838298     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206788     Document Type: Article

References (31)

1. Amorino GP, Hamilton VM, Valeric K, Dent P, Lammering G and Schmidt-Ullrich RK. (2002). Mol. Biol. Cell., 13, 2233-2244.
2. Batra SK, Castelino-Prabhu S, Wikstrand CJ, Zhu X, Humphrey PA, Friedman HS and Bigner DD. (1995). Cell Growth Differ., 6, 1251-1259.
3. Bigner SH, Humphrey PA, Wong AJ, Vogelstein B, Mark J, Friedman HS and Bigner DD. (1990). Cancer Res., 50, 8017-8022.
4. Bowers G, Reardon D, Hewitt T, Dent P, Mikkelsen RB, Valerie K, Lammering G, Amir C and Schmidt-Ullrich RK. (2001). Oncogene, 20, 1388-1397.
5. Chu CT, Everiss KD, Wikstrand CJ, Batra SK, Kung HJ and Bigner DD. (1997). Biochem. J., 324 (Part 3), 855-861.
6. Contessa JN, Hampton J, Lammering G, Mikkelsen RB, Dent P, Valerie K and Schmidt-Ullrich RK. (2002). Oncogene, 21, 4032-4041.
7. Contessa JN, Reardon DB, Todd D, Dent P, Mikkelsen RB, Valerie K, Bowers GD and Schmidt-Ullrich RK. (1999). Clin. Cancer Res., 5, 405-411.
8. Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K and Schmidt-Ullrich R. (1999). Mol. Biol. Cell, 10, 2493-2506.
9. Ekstrand AJ, Longo N, Hamid ML, Olson JJ, Liu L, Collins VP and James CD. (1994). Oncogene, 9, 2313-2320.
10. Frederick L, Wang XY, Eley G and James CD. (2000). Cancer Res., 60, 1383-1387.
11. Han Y, Caday CG, Nanda A, Cavenee WK and Huang HJ. (1996). Cancer Res., 56, 3859-3861.
12. Huang HS, Nagane M, Klingbeil CK, Lin H, Nishikawa R, Ji XD, Huang CM, Gill GN, Wiley HS and Cavenee WK. (1997). J. Biol. Chem., 272, 2927-2935.
13. Kennedy SG, Kandel ES, Cross TK and Hay N. (1999). Mol. Cell. Biol., 19, 5800-5810.
14. Lammering G, Hewit TH, Hawkins WT, Contessa JN, Reardon DB, Lin PS, Valerie K, Dent P, Mikkelsen RB and Schmidt-Ullrich RK. (2001a). J. Natl. Cancer Inst., 93, 921-929.
15. Lammering G, Lin PS, Contessa JN, Hampton JL, Valerie K and Schmidt-Ullrich RK. (2001b). Int. J. Radiat. Oncol. Biol. Phys., 51, 775-784.
16. Lammering G, Valerie K, Lin PS, Mikkelsen RB, Contessa JN, Feden JP, Farnsworth J, Dent P and Schmidt-Ullrich RK. (2001c). Clin. Cancer Res., 7, 682-690.
17. Montgomery RB, Moscatello DK, Wong AJ, Cooper JA and Stahl WL. (1995). J. Biol. Chem., 270, 30562-30566.
18. Moscatello DK, Holgado-Madruga M, Emlet DR, Montgomery RB and Wong AJ. (1998). J. Biol. Chem., 273, 200-206.
19. Moscatello DK, Holgado-Madruga M, Godwin AK, Ramirez G, Gunn G, Zoltick PW, Biegel JA, Hayes RL and Wong AJ. (1995). Cancer Res., 55, 5536-5539.
20. Moscatello DK, Montgomery RB, Sundareshan P, McDanel H, Wong MY and Wong AJ. (1996). Oncogene, 13, 85-96.
21. Nagane M, Coufal F, Lin H, Bogler O, Cavenee WK and Huang HJ. (1996). Cancer Res., 56, 5079-5086.
22. Nishikawa R, Ji XD, Harmon RC, Lazar CS, Gill GN, Cavenee WK and Huang HJ. (1994). Proc. Natl. Acad. Sci. USA, 91, 7727-7731.
23. O'Rourke DM, Kao GD, Singh N, Park BW, Muschel RJ, Wu CJ and Greene MI. (1998a). Proc. Natl. Acad. Sci. USA, 95, 10842-10847.
24. O'Rourke DM, Nute EJ, Davis JG, Wu C, Lee A, Murali R, Zhang HT, Qian X, Kao CC and Greene MI. (1998b). Oncogene, 16, 1197-1207.
25. O'Rourke DM, Qian X, Zhang HT, Davis JG, Nute E, Meinkoth J and Greene MI. (1997). Proc. Natl. Acad. Sci. USA, 94, 3250-3255.
26. Reardon DB, Contessa JN, Mikkelsen RB, Valerie K, Amir C, Dent P and Schmidt-Ullrich RK. (1999). Oncogene, 18, 4756-4766.
27. Schmidt-Ullrich RK, Contessa JN, Dent P, Mikkelsen RB, Valerie K, Reardon DB, Bowers G and Lin PS. (1999). Radiat. Oncol. Invest., 7, 321-330.
28. Schmidt-Ullrich RK, Dent P, Grant S, Mikkelsen RB and Valerie K. (2000). Radiat. Res., 153, 245-257.
29. Schmidt-Ullrich RK, Mikkelsen RB, Dent P, Todd DG, Valerie K, Kavanagh BD, Contessa JN, Rorrer WK and Chen PB. (1997). Oncogene, 15, 1191-1197.
30. Schmidt-Ullrich RK, Valerie K, Fogleman PB and Walters J. (1996). Radiat. Res., 145, 81-85.
31. Wong AJ, Ruppert JM, Bigner SH, Grzeschik CH, Humphrey PA, Bigner DS and Vogelstein B. (1992). Proc. Natl. Acad. Sci. USA, 89, 2965-2969.