Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8 + T cells in early viral evolution

Journal of Virology

Volumn 85, Issue 22, 2011, Pages 11833-11845

  Callendret, Benoît ^a   Bukh, Jens ^b,c,d   Eccleston, Heather B ^a   Heksch, Ryan ^a   Hasselschwert, Dana L ^e   Purcell, Robert H ^b   Hughes, Austin L ^f   Walker, Christopher M ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c HVIDOVRE HOSPITAL   (Denmark)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF LOUISIANA AT LAFAYETTE   (United States)

^f UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CHIMPANZEE; CLONE; CONSENSUS SEQUENCE; CONTROLLED STUDY; GENE MUTATION; GENETIC DRIFT; GENETIC SELECTION; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; MOLECULAR EVOLUTION; NONHUMAN; NONSYNONYMOUS MUTATION; NUCLEOTIDE SEQUENCE; POSITIVE SELECTION PRESSURE; PRIORITY JOURNAL; SYNONYMOUS MUTATION; VIRUS GENOME; VIRUS REPLICATION; VIRUS TRANSMISSION;

AMINO ACID SUBSTITUTION; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CLUSTER ANALYSIS; DISEASE MODELS, ANIMAL; EPITOPES; EVOLUTION, MOLECULAR; GENOME, VIRAL; GENOTYPE; HEPACIVIRUS; HEPATITIS C; MUTATION, MISSENSE; PAN TROGLODYTES; PRIMATE DISEASES; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

HEPATITIS C VIRUS; PAN;

EID: 80655142505     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02654-10     Document Type: Article

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