Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology

Journal of Proteome Research

Volumn 10, Issue 11, 2011, Pages 4935-4947

  Chang, Kai Ping ^a   Yu, Jau Song ^b,c   Chien, Kun Yi ^b,c   Lee, Chien Wei ^c   Liang, Ying ^b   Liao, Chun Ta ^a   Yen, Tzu Chen ^a   Lee, Li Yu ^a   Huang, Ling Ling ^b   Liu, Shiau Chin ^a   Chang, Yu Sun ^b,c   Chi, Lang Ming ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

iTRAQ based proteomics; LCM; metastasis; oral cancer; OSCC; P4HA2; PRDX4

Indexed keywords

PEROXIREDOXIN 4; PROTEIN P4HA2; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CELL FUNCTION; CELL INVASION; CELL MIGRATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; ISOBARIC TAGS FOR RELATIVE AND ABSOLUTE QUANTITATION; LYMPH NODE METASTASIS; METASTASIS; MICRODISSECTION; MOUTH CARCINOMA; MULTIVARIATE ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; UNIVARIATE ANALYSIS;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHROMATOGRAPHY, LIQUID; HUMANS; KAPLAN-MEIER ESTIMATE; LASER CAPTURE MICRODISSECTION; LYMPHATIC METASTASIS; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM PROTEINS; PEROXIREDOXINS; PROCOLLAGEN-PROLINE DIOXYGENASE; PROPORTIONAL HAZARDS MODELS; PROTEOME; TANDEM MASS SPECTROMETRY; UP-REGULATION;

EID: 80655126737     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200311p     Document Type: Article

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