-
1
-
-
1642565876
-
Tumor hypoxia and malignant progression
-
Vaupel P., Mayer A., and Hockel M. Tumor hypoxia and malignant progression. Methods Enzymol. 381 (2004) 335-354
-
(2004)
Methods Enzymol.
, vol.381
, pp. 335-354
-
-
Vaupel, P.1
Mayer, A.2
Hockel, M.3
-
2
-
-
0034021690
-
Hypoxia, clonal selection, and the role of HIF-1 in tumor progression
-
Semenza G.L. Hypoxia, clonal selection, and the role of HIF-1 in tumor progression. Crit. Rev. Biochem. Mol. Biol. 35 (2000) 71-103
-
(2000)
Crit. Rev. Biochem. Mol. Biol.
, vol.35
, pp. 71-103
-
-
Semenza, G.L.1
-
3
-
-
0036216692
-
HIF-1 and tumor progression: pathophysiology and therapeutics
-
Semenza G.L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 8 (2002) S62-S67
-
(2002)
Trends Mol. Med.
, vol.8
-
-
Semenza, G.L.1
-
4
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell P.H., Dachs G.U., Gleadle J.M., Nicholls L.G., Harris A.L., Stratford I.J., Hankinson O., Pugh C.W., and Ratcliffe P.J. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc. Natl. Acad. Sci. USA 94 (1997) 8104-8109
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
Nicholls, L.G.4
Harris, A.L.5
Stratford, I.J.6
Hankinson, O.7
Pugh, C.W.8
Ratcliffe, P.J.9
-
5
-
-
0036569941
-
Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients
-
Beasley N.J., Leek R., Alam M., Turley H., Cox G.J., Gatter K., Millard P., Fuggle S., and Harris A.L. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 62 (2002) 2493-2497
-
(2002)
Cancer Res.
, vol.62
, pp. 2493-2497
-
-
Beasley, N.J.1
Leek, R.2
Alam, M.3
Turley, H.4
Cox, G.J.5
Gatter, K.6
Millard, P.7
Fuggle, S.8
Harris, A.L.9
-
6
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H., De Marzo A.M., Laughner E., Lim M., Hilton D.A., Zagzag D., Buechler P., Isaacs W.B., Semenza G.L., and Simons J.W. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res. 59 (1999) 5830-5835
-
(1999)
Cancer Res.
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
Buechler, P.7
Isaacs, W.B.8
Semenza, G.L.9
Simons, J.W.10
-
7
-
-
0038751965
-
Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression
-
Acs G., Zhang P.J., McGrath C.M., Acs P., McBroom J., Mohyeldin A., Liu S., Lu H., and Verma A. Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am. J. Pathol. 162 (2003) 1789-1806
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1789-1806
-
-
Acs, G.1
Zhang, P.J.2
McGrath, C.M.3
Acs, P.4
McBroom, J.5
Mohyeldin, A.6
Liu, S.7
Lu, H.8
Verma, A.9
-
9
-
-
0026542056
-
Integrin expression in human melanoma cells with differing invasive and metastatic properties
-
Gehlsen K.R., Davis G.E., and Sriramarao P. Integrin expression in human melanoma cells with differing invasive and metastatic properties. Clin. Exp. Metastasis 10 (1992) 111-120
-
(1992)
Clin. Exp. Metastasis
, vol.10
, pp. 111-120
-
-
Gehlsen, K.R.1
Davis, G.E.2
Sriramarao, P.3
-
10
-
-
0026451947
-
Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin
-
Nip J., Shibata H., Loskutoff D.J., Cheresh D.A., and Brodt P. Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin. J. Clin. Invest. 90 (1992) 1406-1413
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1406-1413
-
-
Nip, J.1
Shibata, H.2
Loskutoff, D.J.3
Cheresh, D.A.4
Brodt, P.5
-
11
-
-
0035019920
-
Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta4 integrin
-
Mercurio A.M., and Rabinovitz I. Towards a mechanistic understanding of tumor invasion-lessons from the alpha6beta4 integrin. Semin. Cancer Biol. 11 (2001) 129-141
-
(2001)
Semin. Cancer Biol.
, vol.11
, pp. 129-141
-
-
Mercurio, A.M.1
Rabinovitz, I.2
-
12
-
-
0031059664
-
Exposure to hypoxia, glucose starvation and acidosis: effect on invasive capacity of murine tumor cells and correlation with cathepsin (L + B) secretion
-
Cuvier C., Jang A., and Hill R.P. Exposure to hypoxia, glucose starvation and acidosis: effect on invasive capacity of murine tumor cells and correlation with cathepsin (L + B) secretion. Clin. Exp. Metastasis 15 (1997) 19-25
-
(1997)
Clin. Exp. Metastasis
, vol.15
, pp. 19-25
-
-
Cuvier, C.1
Jang, A.2
Hill, R.P.3
-
13
-
-
0033521864
-
Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression
-
Graham C.H., Forsdike J., Fitzgerald C.J., and Macdonald-Goodfellow S. Hypoxia-mediated stimulation of carcinoma cell invasiveness via upregulation of urokinase receptor expression. Int. J. Cancer 80 (1999) 617-623
-
(1999)
Int. J. Cancer
, vol.80
, pp. 617-623
-
-
Graham, C.H.1
Forsdike, J.2
Fitzgerald, C.J.3
Macdonald-Goodfellow, S.4
-
14
-
-
0034213146
-
Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression
-
Zagzag D., Zhong H., Scalzitti J.M., Laughner E., Simons J.W., and Semenza G.L. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88 (2000) 2606-2618
-
(2000)
Cancer
, vol.88
, pp. 2606-2618
-
-
Zagzag, D.1
Zhong, H.2
Scalzitti, J.M.3
Laughner, E.4
Simons, J.W.5
Semenza, G.L.6
-
15
-
-
57349164238
-
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells
-
Cannito S., Novo E., Compagnone A., Valfre di Bonzo L., Busletta C., Zamara E., Paternostro C., Povero D., Bandino A., Bozzo F., Cravanzola C., Bravoco V., Colombatto S., and Parola M. Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells. Carcinogenesis 29 (2008) 2267-2278
-
(2008)
Carcinogenesis
, vol.29
, pp. 2267-2278
-
-
Cannito, S.1
Novo, E.2
Compagnone, A.3
Valfre di Bonzo, L.4
Busletta, C.5
Zamara, E.6
Paternostro, C.7
Povero, D.8
Bandino, A.9
Bozzo, F.10
Cravanzola, C.11
Bravoco, V.12
Colombatto, S.13
Parola, M.14
-
16
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1
-
Krishnamachary B., Berg-Dixon S., Kelly B., Agani F., Feldser D., Ferreira G., Iyer N., LaRusch J., Pak B., Taghavi P., and Semenza G.L. Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1. Cancer Res. 63 (2003) 1138-1143
-
(2003)
Cancer Res.
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
Iyer, N.7
LaRusch, J.8
Pak, B.9
Taghavi, P.10
Semenza, G.L.11
-
17
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat. Rev. Cancer 3 (2003) 721-732
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
18
-
-
2542588628
-
Hypoxia induces adhesion molecules on cancer cells: a missing link between Warburg effect and induction of selectin-ligand carbohydrates
-
Koike T., Kimura N., Miyazaki K., Yabuta T., Kumamoto K., Takenoshita S., Chen J., Kobayashi M., Hosokawa M., Taniguchi A., Kojima T., Ishida N., Kawakita M., Yamamoto H., Takematsu H., Suzuki A., Kozutsumi Y., and Kannagi R. Hypoxia induces adhesion molecules on cancer cells: a missing link between Warburg effect and induction of selectin-ligand carbohydrates. Proc. Natl. Acad. Sci. USA 101 (2004) 8132-8137
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8132-8137
-
-
Koike, T.1
Kimura, N.2
Miyazaki, K.3
Yabuta, T.4
Kumamoto, K.5
Takenoshita, S.6
Chen, J.7
Kobayashi, M.8
Hosokawa, M.9
Taniguchi, A.10
Kojima, T.11
Ishida, N.12
Kawakita, M.13
Yamamoto, H.14
Takematsu, H.15
Suzuki, A.16
Kozutsumi, Y.17
Kannagi, R.18
-
19
-
-
33645730359
-
ERBB2-mediated transcriptional up-regulation of the alpha5beta1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions
-
Spangenberg C., Lausch E.U., Trost T.M., Prawitt D., May A., Keppler R., Fees S.A., Reutzel D., Bell C., Schmitt S., Schiffer I.B., Weber A., Brenner W., Hermes M., Sahin U., Tureci O., Koelbl H., Hengstler J.G., and Zabel B.U. ERBB2-mediated transcriptional up-regulation of the alpha5beta1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions. Cancer Res. 66 (2006) 3715-3725
-
(2006)
Cancer Res.
, vol.66
, pp. 3715-3725
-
-
Spangenberg, C.1
Lausch, E.U.2
Trost, T.M.3
Prawitt, D.4
May, A.5
Keppler, R.6
Fees, S.A.7
Reutzel, D.8
Bell, C.9
Schmitt, S.10
Schiffer, I.B.11
Weber, A.12
Brenner, W.13
Hermes, M.14
Sahin, U.15
Tureci, O.16
Koelbl, H.17
Hengstler, J.G.18
Zabel, B.U.19
-
20
-
-
1942533531
-
Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene
-
Wykoff C.C., Sotiriou C., Cockman M.E., Ratcliffe P.J., Maxwell P., Liu E., and Harris A.L. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br. J. Cancer 90 (2004) 1235-1243
-
(2004)
Br. J. Cancer
, vol.90
, pp. 1235-1243
-
-
Wykoff, C.C.1
Sotiriou, C.2
Cockman, M.E.3
Ratcliffe, P.J.4
Maxwell, P.5
Liu, E.6
Harris, A.L.7
-
21
-
-
0141869070
-
Investigating hypoxic tumor physiology through gene expression patterns
-
Denko N.C., Fontana L.A., Hudson K.M., Sutphin P.D., Raychaudhuri S., Altman R., and Giaccia A.J. Investigating hypoxic tumor physiology through gene expression patterns. Oncogene 22 (2003) 5907-5914
-
(2003)
Oncogene
, vol.22
, pp. 5907-5914
-
-
Denko, N.C.1
Fontana, L.A.2
Hudson, K.M.3
Sutphin, P.D.4
Raychaudhuri, S.5
Altman, R.6
Giaccia, A.J.7
-
22
-
-
69249129752
-
Up-regulation of alpha5-integrin by E-cadherin loss in hypoxia and its key role in the migration of extravillous trophoblast cells during early implantation
-
Arimoto-Ishida E., Sakata M., Sawada K., Nakayama M., Nishimoto F., Mabuchi S., Takeda T., Yamamoto T., Isobe A., Okamoto Y., Lengyel E., Suehara N., Morishige K., and Kimura T. Up-regulation of alpha5-integrin by E-cadherin loss in hypoxia and its key role in the migration of extravillous trophoblast cells during early implantation. Endocrinology 150 (2009) 4306-4315
-
(2009)
Endocrinology
, vol.150
, pp. 4306-4315
-
-
Arimoto-Ishida, E.1
Sakata, M.2
Sawada, K.3
Nakayama, M.4
Nishimoto, F.5
Mabuchi, S.6
Takeda, T.7
Yamamoto, T.8
Isobe, A.9
Okamoto, Y.10
Lengyel, E.11
Suehara, N.12
Morishige, K.13
Kimura, T.14
-
23
-
-
0032079312
-
Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway
-
Graham C.H., Fitzpatrick T.E., and McCrae K.R. Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway. Blood 91 (1998) 3300-3307
-
(1998)
Blood
, vol.91
, pp. 3300-3307
-
-
Graham, C.H.1
Fitzpatrick, T.E.2
McCrae, K.R.3
-
24
-
-
59649126066
-
N-Acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5beta1 integrin
-
Yamamoto E., Ino K., Miyoshi E., Inamori K., Abe A., Sumigama S., Iwase A., Kajiyama H., Shibata K., Nawa A., and Kikkawa F. N-Acetylglucosaminyltransferase V regulates extravillous trophoblast invasion through glycosylation of alpha5beta1 integrin. Endocrinology 150 (2009) 990-999
-
(2009)
Endocrinology
, vol.150
, pp. 990-999
-
-
Yamamoto, E.1
Ino, K.2
Miyoshi, E.3
Inamori, K.4
Abe, A.5
Sumigama, S.6
Iwase, A.7
Kajiyama, H.8
Shibata, K.9
Nawa, A.10
Kikkawa, F.11
|