Survivin inhibition and DNA double-strand break repair: A molecular mechanism to overcome radioresistance in glioblastoma

Radiotherapy and Oncology

Volumn 101, Issue 1, 2011, Pages 51-58

  Reichert, Sebastian ^a   Rödel, Claus ^a   Mirsch, Johanna ^a   Harter, Patrick N ^a   Tomicic, Maja T ^b   Mittelbronn, Michel ^a   Kaina, Bernd ^b   Rödel, Franz ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Apoptosis; DNA PKcs; DNA repair; Glioblastoma; Phospho histone H2AX; Survivin

Indexed keywords

BINDING PROTEIN; CASPASE 3; CASPASE 7; HISTONE H2AX; PROTEIN KINASE; SMALL INTERFERING RNA; SURVIVIN;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CLONOGENIC ASSAY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GEL ELECTROPHORESIS; GLIOBLASTOMA; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; STAINING; SURVIVAL;

APOPTOSIS; CASPASES; CELL SURVIVAL; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; IMMUNOPRECIPITATION; INHIBITOR OF APOPTOSIS PROTEINS; RADIATION DOSAGE; RADIATION TOLERANCE; RADIATION, IONIZING; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED;

EID: 80655124597     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2011.06.037     Document Type: Article

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