메뉴 건너뛰기




Volumn 414, Issue 4, 2011, Pages 694-699

Relevance of the OCT1 transporter to the antineoplastic effect of biguanides

Author keywords

Biguanides; Cancer; Metformin; Organic cation transporter 1; Phenformin

Indexed keywords

ADENYLATE KINASE; BIGUANIDE DERIVATIVE; METFORMIN; ORGANIC CATION TRANSPORTER 1; PHENFORMIN; SMALL INTERFERING RNA;

EID: 80555149233     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.09.134     Document Type: Article
Times cited : (73)

References (28)
  • 1
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 2008, 8:915-928.
    • (2008) Nat Rev Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 3
    • 61449113987 scopus 로고    scopus 로고
    • The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase
    • Zakikhani M., Dowling R.J., Sonenberg N., Pollak M.N. The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase. Cancer Prev Res (Phila) 2008, 1:369-375.
    • (2008) Cancer Prev Res (Phila) , vol.1 , pp. 369-375
    • Zakikhani, M.1    Dowling, R.J.2    Sonenberg, N.3    Pollak, M.N.4
  • 4
    • 0036224169 scopus 로고    scopus 로고
    • Homocysteine induces protein kinase C activation and stimulates c-Fos and lipoprotein lipase expression in macrophages
    • Beauchamp M.C., Renier G. Homocysteine induces protein kinase C activation and stimulates c-Fos and lipoprotein lipase expression in macrophages. Diabetes 2002, 51:1180-1187.
    • (2002) Diabetes , vol.51 , pp. 1180-1187
    • Beauchamp, M.C.1    Renier, G.2
  • 6
    • 79955834631 scopus 로고    scopus 로고
    • Metformin suppresses ovarian cancer growth and metastasis with enhancement of Cisplatin cytotoxicity in vivo
    • Rattan R., Graham R.P., Maguire J.L., Giri S., Shridhar V. Metformin suppresses ovarian cancer growth and metastasis with enhancement of Cisplatin cytotoxicity in vivo. Neoplasia 2011, 13:483-491.
    • (2011) Neoplasia , vol.13 , pp. 483-491
    • Rattan, R.1    Graham, R.P.2    Maguire, J.L.3    Giri, S.4    Shridhar, V.5
  • 8
    • 67649958571 scopus 로고    scopus 로고
    • Current status and challenges associated with targeting mTOR for cancer therapy
    • Dowling R.J., Pollak M., Sonenberg N. Current status and challenges associated with targeting mTOR for cancer therapy. BioDrugs 2009, 23:77-91.
    • (2009) BioDrugs , vol.23 , pp. 77-91
    • Dowling, R.J.1    Pollak, M.2    Sonenberg, N.3
  • 9
    • 36348950449 scopus 로고    scopus 로고
    • Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
    • Dowling R.J., Zakikhani M., Fantus I.G., Pollak M., Sonenberg N. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. Cancer Res 2007, 67:10804-10812.
    • (2007) Cancer Res , vol.67 , pp. 10804-10812
    • Dowling, R.J.1    Zakikhani, M.2    Fantus, I.G.3    Pollak, M.4    Sonenberg, N.5
  • 10
    • 17144474893 scopus 로고    scopus 로고
    • Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, Phenformin, and AICAR
    • Sakamoto K., Goransson O., Hardie D.G., Alessi D.R. Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, Phenformin, and AICAR. Am J Physiol Endocrinol Metab 2004, 287:E310-E317.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Sakamoto, K.1    Goransson, O.2    Hardie, D.G.3    Alessi, D.R.4
  • 11
    • 0031733673 scopus 로고    scopus 로고
    • Phenformin and lactic acidosis: a case report and review
    • Kwong S.C., Brubacher J. Phenformin and lactic acidosis: a case report and review. J Emerg Med 1998, 16:881-886.
    • (1998) J Emerg Med , vol.16 , pp. 881-886
    • Kwong, S.C.1    Brubacher, J.2
  • 13
    • 0018895934 scopus 로고
    • Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice
    • Dilman V.M., Anisimov V.N. Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice. Gerontology 1980, 26:241-246.
    • (1980) Gerontology , vol.26 , pp. 241-246
    • Dilman, V.M.1    Anisimov, V.N.2
  • 14
    • 0019477055 scopus 로고
    • Inhibiting effect of phenformin (phenethyl biguanide) on the growth of Ehrlich carcinoma
    • Shikhman A.R., Lebedev K.A., Dil'man V.M. Inhibiting effect of phenformin (phenethyl biguanide) on the growth of Ehrlich carcinoma. Vopr Onkol 1981, 27:67-69.
    • (1981) Vopr Onkol , vol.27 , pp. 67-69
    • Shikhman, A.R.1    Lebedev, K.A.2    Dil'man, V.M.3
  • 17
    • 78649646556 scopus 로고    scopus 로고
    • Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy
    • Nies A.T., Koepsell H., Damme K., Schwab M. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy. Handb Exp Pharmacol 2011, 105-167.
    • (2011) Handb Exp Pharmacol , pp. 105-167
    • Nies, A.T.1    Koepsell, H.2    Damme, K.3    Schwab, M.4
  • 18
    • 70549094220 scopus 로고    scopus 로고
    • A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes
    • Sogame Y., Kitamura A., Yabuki M., Komuro S. A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes. Biopharm Drug Dispos 2009, 30:476-484.
    • (2009) Biopharm Drug Dispos , vol.30 , pp. 476-484
    • Sogame, Y.1    Kitamura, A.2    Yabuki, M.3    Komuro, S.4
  • 24
    • 34249943356 scopus 로고    scopus 로고
    • Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications
    • Koepsell H., Lips K., Volk C. Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications. Pharm Res 2007, 24:1227-1251.
    • (2007) Pharm Res , vol.24 , pp. 1227-1251
    • Koepsell, H.1    Lips, K.2    Volk, C.3
  • 25
    • 0034614420 scopus 로고    scopus 로고
    • Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
    • El-Mir M.Y., Nogueira V., Fontaine E., Averet N., Rigoulet M., Leverve X. Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem 2000, 275:223-228.
    • (2000) J Biol Chem , vol.275 , pp. 223-228
    • El-Mir, M.Y.1    Nogueira, V.2    Fontaine, E.3    Averet, N.4    Rigoulet, M.5    Leverve, X.6
  • 27
    • 79952538201 scopus 로고    scopus 로고
    • Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo
    • Algire C., Amrein L., Bazile M., David S., Zakikhani M., Pollak M. Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo. Oncogene 2011, 30:1174-1182.
    • (2011) Oncogene , vol.30 , pp. 1174-1182
    • Algire, C.1    Amrein, L.2    Bazile, M.3    David, S.4    Zakikhani, M.5    Pollak, M.6
  • 28
    • 77956401999 scopus 로고    scopus 로고
    • Metformin other biguanides in oncology: advancing the research agenda
    • Pollak M. Metformin other biguanides in oncology: advancing the research agenda. Cancer Prev Res (Phila) 2010, 3:1060-1065.
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 1060-1065
    • Pollak, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.