A comparison of uptake of metformin and phenformin mediated by hOCT1 in human hepatocytes

Biopharmaceutics and Drug Disposition

Volumn 30, Issue 8, 2009, Pages 476-484

  Sogame, Yoshihisa ^a   Kitamura, Atsushi ^a   Yabuki, Masashi ^a   Komuro, Setsuko ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Hepatocytes; Human organic cation transporter 1 (hOCT1); Metformin; Oocytes; Phenformin

Indexed keywords

CARBON 14; METFORMIN; ORGANIC CATION TRANSPORTER 1; PHENFORMIN; POTASSIUM ION;

ACTIVE TRANSPORT; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG PROTEIN BINDING; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; LIVER CELL; LIVER FUNCTION; NONHUMAN; PASSIVE TRANSPORT; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSPORT KINETICS;

ALANINE TRANSAMINASE; ANIMALS; BILE ACIDS AND SALTS; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; CRICETULUS; HEPATOCYTES; HUMANS; HYPOGLYCEMIC AGENTS; LIVER; METFORMIN; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1; PHENFORMIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 70549094220     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.684     Document Type: Article

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