Induction of apoptosis by metformin in epithelial ovarian cancer: Involvement of the Bcl-2 family proteins

Gynecologic Oncology

Volumn 121, Issue 3, 2011, Pages 492-498

  Yasmeen, Amber ^a,b   Beauchamp, Marie Claude ^a,b   Piura, Ettie ^b   Segal, Eric ^a,b   Pollak, Michael ^b   Gotlieb, Walter H ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Apoptosis; Bcl 2; Metformin; Ovarian cancer

Indexed keywords

CASPASE 3; CASPASE 7; CISPLATIN; METFORMIN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOWN REGULATION; EPTHELIAL OVARIAN CANCER; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOW CYTOMETRY; HUMANS; METFORMIN; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 79957438835     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2011.02.021     Document Type: Article

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