Suppression of pro-inflammatory and proliferative pathways by diferuloylmethane (curcumin) and its analogues dibenzoylmethane, dibenzoylpropane, and dibenzylideneacetone: Role of Michael acceptors and Michael donors

Biochemical Pharmacology

Volumn 82, Issue 12, 2011, Pages 1901-1909

  Anand, Preetha ^a   Sung, Bokyung ^a   Kunnumakkara, Ajaikumar B ^a   Rajasekharan, Kallikat N ^b   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF KERALA   (India)

Author keywords

Cell proliferation; Curcumin analogues; Michael acceptor; NF B

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CURCUMIN; CYCLIN D1; CYCLOOXYGENASE 2; DIBENZOYLMETHANE; DIBENZOYLPROPANE; DIBENZYLIDENEACETONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL PROLIFERATION; DRUG DNA BINDING; DRUG POTENCY; GENE CONTROL; GENE REPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MICHAEL ADDITION; PRIORITY JOURNAL;

ANGIOGENIC PROTEINS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONES; CURCUMIN; GENE EXPRESSION REGULATION; HUMANS; MAP KINASE KINASE KINASES; MOLECULAR STRUCTURE; PENTANONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80555131124     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.09.001     Document Type: Article

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