Induction of apoptosis by hydroxydibenzoylmethane through coordinative modulation of cyclin D3, Bcl-XL, and Bax, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells

Journal of Agricultural and Food Chemistry

Volumn 51, Issue 14, 2003, Pages 3977-3984

  Pan, Min Hsiung ^a   Huang, Mei Chen ^a,d   Wang, Ying Jan ^b   Lin, Jen Kun ^c   Lin, Chao Hsien ^d  

^a NATIONAL KAOHSIUNG UNIVERSITY OF APPLIED SCIENCES   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Apoptosis; Caspase 2; Caspase 3; Caspase 9; Caspase activated deoxyribonuclease; Cytochrome c; DBM; DNA fragmentation factor; HDB; HMDB; Poly (ADP ribose) polymerase

Indexed keywords

ANTIMUTAGENIC AGENT; CASPASE; CASPASE 2; CASPASE 3; CYCLIN D3; CYTOCHROME C; DEOXYRIBONUCLEASE; DIKETONE; ENZYME INHIBITOR; ENZYME PRECURSOR; HYDROXYDIBENZOYLMETHANE; HYDROXYMETHYLDIBENZOYLMETHANE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P21; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL LINE; CELL STRAIN COLO 205; CELL VIABILITY; CHEMOPROPHYLAXIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; DNA DEGRADATION; DNA STRAND BREAKAGE; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; GENE EXPRESSION; GLYCYRRHIZA; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BENZOATES; CASPASE 3; CASPASES; CELL SURVIVAL; CHALCONES; COLORECTAL NEOPLASMS; CYCLINS; CYTOCHROME C GROUP; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE EXPRESSION; HUMANS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

GLYCYRRHIZA;

EID: 0038353471     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf034094i     Document Type: Article

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