Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA-Rock and Src-FAK signalling in colon cancer cells

European Journal of Pharmacology

Volumn 671, Issue 1-3, 2011, Pages 7-17

  Leve, Fernanda ^a   Marcondes, Taline Guimarães Corrêa ^a   Bastos, Lilian Gonçalves R ^a   Rabello, Sarah Vieira ^a   Tanaka, Marcelo Neves ^a   Morgado Díaz, José Andrés ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Actin cytoskeleton; Adherent junction; Cell migration; Colorectal cancer; Lysophosphatidic acid; Rho GTPase

Indexed keywords

ACTIN; FOCAL ADHESION KINASE; LYSOPHOSPHATIDIC ACID; PROTEIN TYROSINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ROCK PROTEIN; SRC PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL JUNCTION; CELL MIGRATION; CELL STRAIN CACO 2; COLON CANCER; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVATION; FOCAL ADHESION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WOUND HEALING;

ADHERENS JUNCTIONS; CACO-2 CELLS; CELL MOVEMENT; COLONIC NEOPLASMS; DISEASE PROGRESSION; FOCAL ADHESION KINASE 1; FOCAL ADHESIONS; HUMANS; LYSOPHOSPHOLIPIDS; PHENOTYPE; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; STRESS FIBERS;

EID: 80455160168     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.09.006     Document Type: Article

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