Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell-cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells

Cancer Chemotherapy and Pharmacology

Volumn 68, Issue 1, 2011, Pages 227-238

  De Freitas Jr , Julio Cesar Madureira ^a   Silva, Bárbara Du Rocher D'Aguiar ^a   De Souza, Waldemir Fernandes ^a   De Araújo, Wallace Martins ^a   Abdelhay, Eliana Saul Furquim Werneck ^a   Morgado Díaz, José Andrés ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Adherens junctions; Colorectal cancer; E cadherin; N glycosylation; Swainsonine; Tunicamycin

Indexed keywords

ERYTHROAGGLUTININ; GLYCAN; LEUKOAGGLUTININ; PLANT LECTIN; SWAINSONINE; TUNICAMYCIN; UNCLASSIFIED DRUG; UVOMORULIN;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL JUNCTION; CELL PROLIFERATION; CELL STRAIN CACO 2; CELL STRAIN HCT116; COLORECTAL CANCER; CONTROLLED STUDY; DRUG MECHANISM; ELECTRON MICROSCOPY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PHASEOLUS VULGARIS; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN SYNTHESIS; WESTERN BLOTTING;

ADHERENS JUNCTIONS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CACO-2 CELLS; CADHERINS; CALCIUM; CELL ADHESION; CELL PROLIFERATION; COLONIC NEOPLASMS; GLYCOSYLATION; HCT116 CELLS; HUMANS; MICE; POLYSACCHARIDES; TUNICAMYCIN;

EID: 79959630759     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-010-1477-8     Document Type: Article

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