Comparison of 4 radiolabeled antagonists for serotonin 5-HT 7 receptor neuroimaging: Toward the first PET radiotracer

Journal of Nuclear Medicine

Volumn 52, Issue 11, 2011, Pages 1811-1818

  Lemoine, Laetitia ^a,b   Andries, Julien ^c   Le Bars, Didier ^a,c,d   Billard, Thierry ^a,c   Zimmer, Luc ^a,b,d  

^a CERMEP IMAGERIE DU VIVANT   (France)

^b UNIVERSITÉ LYON 1   (France)

^c UNIVERSITÉ LYON 1   (France)

^d HOSPICES CIVILS DE LYON   (France)

Author keywords

5 HT 7 receptors; Cat; PET; Rat; Tracer development

Indexed keywords

1 [2 [1 [(FLUOROPHENYL)SULFONYL]PYRROLIDIN 2 YL]ETHYL] 4 (2 METHOXYPHENYL)PIPERAZINE DERIVATIVE; 1 [2 [1 [(FLUOROPHENYL)SULFONYL]PYRROLIDIN 2 YL]ETHYL] 4 METHYLPIPERIDINE DERIVATIVE; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; FLUORINE 18; SEROTONIN 7 RECEPTOR; SEROTONIN 7 RECEPTOR ANTAGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BLOOD BRAIN BARRIER; CELL ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG DISTRIBUTION; DRUG EFFECT; DRUG METABOLISM; DRUG PENETRATION; DRUG PURITY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EX VIVO STUDY; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; LIPOPHILICITY; MALE; NEUROIMAGING; NONHUMAN; NUCLEOPHILICITY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RADIOACTIVITY; RADIOCHEMISTRY; RAT; RECEPTOR BLOCKING;

ANIMALS; BIOLOGICAL TRANSPORT; BRAIN; CATS; ISOTOPE LABELING; MALE; NEUROIMAGING; PIPERAZINES; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS; RATS; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SPECIES SPECIFICITY;

EID: 80455132099     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.111.089185     Document Type: Article

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