Selective inhibition of 5-HT7 receptor reduces CGRP release in an experimental model for migraine

Headache

Volumn 50, Issue 4, 2010, Pages 579-587

  Wang, Xiaojuan ^a   Fang, Yannan ^a   Liang, Jianbo ^a   Yin, Zhao ^a   Miao, Jiayin ^a   Luo, Ning ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Calcitonin gene related peptide; Migraine; Serotonin 5 HT7 receptor; Trigeminovascular system

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; AS 19; CALCITONIN GENE RELATED PEPTIDE; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; SUMATRIPTAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ELECTROSTIMULATION; EVOKED BRAIN STEM RESPONSE; JUGULAR VEIN; MALE; MIGRAINE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SPRAGUE DAWLEY RAT; TRIGEMINUS GANGLION;

ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CALMODULIN-BINDING PROTEINS; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; MALE; MIGRAINE DISORDERS; MYOSIN-LIGHT-CHAIN KINASE; NEURAL INHIBITION; NOCICEPTORS; PEPTIDE FRAGMENTS; PHENOLS; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SENSORY RECEPTOR CELLS; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SULFONAMIDES; TRIGEMINAL GANGLION; TRIGEMINAL NERVE; TRYPTAMINES;

EID: 77950534272     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2010.01632.x     Document Type: Article

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